Cell Therapy of Corneal Diseases.

abstract：PURPOSE:To evaluate changes in the anterior chamber of eyes that have undergone Descemet membrane endothelial keratoplasty (DMEK) and to identify factors that affect these changes. METHODS:This retrospective study included 25 pseudophakic eyes of 25 patients who underwent DMEK. We determined the preoperative and posto...

journal_title：Cornea

authors： Onouchi H,Hayashi T,Shimizu T,Matsuzawa A,Suzuki Y,Kato N

更新日期：2020-09-29 00:00:00

abstract：PURPOSE:To study the tolerance and biocompatibility of mineral pigments for corneal pigmentation histopathologically and immunologically in an experimental animal model. METHODS:Manual intralamellar keratopigmentation was performed in 28 New Zealand white rabbits using micronized mineral pigments. Histopathological ex...

journal_title：Cornea

authors： Amesty MA,Rodriguez AE,Hernández E,De Miguel MP,Alio JL

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To examine the carbohydrate sulfotransferase 6 (CHST6) gene in Chinese patients with macular corneal dystrophy (MCD). METHODS:Nineteen unrelated Chinese families with MCD, including 24 patients and 3 unaffected relatives, were examined. Genomic DNA was extracted from peripheral blood leukocytes. The coding reg...

journal_title：Cornea

authors： Liu Z,Tian X,Iida N,Fujiki K,Xie P,Wang W,Ma Z,Kanai A,Murakami A

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:The purpose of this research is 2-fold. First of all, the level of keratopathy development in patients with congenital aniridia is studied. In addition, a correlation between the effects of ocular surgery on the severity of keratopathy is made. METHODS:A thorough search for the total number of patients with an...

journal_title：Cornea

authors： Edén U,Riise R,Tornqvist K

更新日期：2010-10-01 00:00:00

abstract：PURPOSE:To compare corneal endothelial cell loss after cataract surgery by phacoemulsification and by Aqualase. METHODS:This was a prospective, randomized study of 75 eyes of 75 patients undergoing cataract surgery. Patients were randomly assigned to receive either phacoemulsification or Aqualase for cataract removal....

journal_title：Cornea

authors： Hu V,Hughes EH,Patel N,Whitefield LA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To compare endothelial cell analysis by the center and flex-center methods in corneas with guttae of differing severity and to determine the minimum countable cell number for using only the flex-center method. METHODS:Forty-seven eyes with corneal guttae and 50 age-matched normal controls were enrolled in the ...

journal_title：Cornea

authors： Huang J,Liu X,Tepelus TC,Nazikyan T,Chopra V,Sadda SR,Lee OL

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To report the histopathologic findings in the host tissue of 2 human keratoconic corneas undergoing maximum-depth anterior lamellar keratoplasty (MDALK) using the manual dissection technique described by Melles. METHODS:Corneal buttons were examined from 2 patients with keratoconus who underwent MDALK using th...

journal_title：Cornea

authors： Saw VP,Ng T,Crouch R,Maloof AJ

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...

journal_title：Cornea

authors： Chen D,Liu Y,Shu G,Chen C,Sullivan DA,Kam WR,Hann S,Fowler M,Warman ML

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the possibility of light damage to the retina by a surgical microscope during implantation of a Boston Keratoprosthesis (B-KPro) in rabbits. METHODS:The retinal irradiance from a Zeiss OPMI Lumera S7 operating microscope was measured at the working distance (16.5 cm). Light ...

journal_title：Cornea

authors： Salvador-Culla B,Behlau I,Sayegh RR,Stacy RC,Dohlman CH,Delori F

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:To report that spontaneous postkeratoplasty wound dehiscence or gaps caused by suture removal may occur years after penetrating and deep lamellar keratoplasty. METHODS:We retrospectively reviewed the medical records of 667 keratoplasty patients (890 eyes). This study included 8 eyes of 8 patients (3 men and 5 ...

journal_title：Cornea

authors： Fujii S,Matsumoto Y,Fukui M,Fujitake J,Kawakita T,Shimmura S,Tsubota K

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To evaluate outcomes of endothelial keratoplasty (EK) without Descemet membrane stripping for treatment of failed penetrating keratoplasty (PKP). METHODS:Retrospective cohort study of all eyes that underwent EK without Descemet membrane stripping for failed PKP at one institution between May 2008 and June 2010...

journal_title：Cornea

authors： Heitor de Paula F,Kamyar R,Shtein RM,Sugar A,Mian SI

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To evaluate changes in the donor corneal endothelium in the intact globe and in the in vivo rabbit cornea to characterize more fully the formation of "dark events" without relief images in the endothelial mosaic. METHODS:Six ex vivo human donor corneas in the intact globe and an in vivo rabbit model were used ...

journal_title：Cornea

authors： Nartey IN,Cavanagh HD,Jester JV,Andrews P,Petroll WM

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To present outcomes of combined pars plana vitrectomy, silicone oil (SO) injection, and permanent keratoprosthesis (Kpro) procedure in prephthisical eyes. METHODS:All 3 patients were monocular with chronic severe hypotony, aphakia, and total corneal opacity in their vital eye. Preoperative visual acuity ranged...

journal_title：Cornea

authors： Utine CA,Gehlbach PL,Zimmer-Galler I,Akpek EK

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:To evaluate the incidence, clinical course, and management of fungal interface keratitis (IK) after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This is a single-center retrospective observational case series of 3950 eyes undergoing DMEK. Six eyes with fungal IK were detected and analyzed. Analys...

journal_title：Cornea

authors： Augustin VA,Weller JM,Kruse FE,Tourtas T

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...

journal_title：Cornea

authors： Yoeruek E,Saygili O,Spitzer MS,Tatar O,Bartz-Schmidt KU,Szurman P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To evaluate clinical and ultrasonographic findings associated with advanced microbial keratitis with concurrent endophthalmitis. METHODS:We performed a retrospective analytical study of patients with severe microbial keratitis who underwent ocular ultrasonography for possible endophthalmitis at our institution...

journal_title：Cornea

authors： Christopher KL,Hood CT,Mian SI,Ayres B

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To evaluate endothelial cell damage after eye bank preparation and passage through 1 of 2 different injectors for Descemet membrane endothelial keratoplasty grafts. METHODS:Eighteen Descemet membrane endothelial keratoplasty grafts were prepared by Lions VisionGift with the standard partial prepeel technique a...

journal_title：Cornea

authors： Schallhorn JM,Holiman JD,Stoeger CG,Chamberlain W

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:The aim of this study is to expand the limited knowledge regarding autologous contralateral penetrating keratoplasty. METHODS:We report the retrospective outcomes of patients who received autokeratoplasty and contralateral opaque corneas in the donor eye at a tertiary care ophthalmology hospital in Mexico City...

journal_title：Cornea

authors： Perez-Balbuena AL,Ancona-Lezama D,Delgado-Pelayo S,Martinez JD

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To report a case of delayed bilateral Descemet's detachment with spontaneous resolution in one eye following successful treatment of the fellow eye. METHOD:Case report. RESULTS:A 78-year-old male who underwent uncomplicated bilateral cataract extraction with phacoemulsification developed delayed bilateral Des...

journal_title：Cornea

authors： Couch SM,Baratz KH

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the reliability of tear film osmolarity as a diagnostic tool for detecting dry eye disease (DED) in patients with rheumatoid arthritis (RA). The second aim was to determine whether there is a relationship between tear film osmolarity, a commonly used RA score, and diagnosti...

journal_title：Cornea

authors： Schargus M,Wolf F,Tony HP,Meyer-Ter-Vehn T,Geerling G

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To investigate the effects of diquafosol sodium (DQS) eye drops, a purinergic P2Y2 receptor agonist, on tear film stability in patients with unstable tear film (UTF). METHODS:Two prospective studies were conducted. One was an exploratory nonrandomized trial on 39 eyes with dry eye symptoms and short tear film ...

journal_title：Cornea

authors： Shimazaki-Den S,Iseda H,Dogru M,Shimazaki J

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:To report a case of corneal endothelial deposits associated with rifabutin therapy for Crohn's disease. METHOD:Case report, anterior segment photography, and current literature search. RESULTS:Persistence of corneal endothelial deposits was found to occur in a 55-year-old gentleman 6 years after cessation of ...

journal_title：Cornea

authors： Williams K,Ilari L

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...

journal_title：Cornea

authors： Panda A,Jain M,Vanathi M,Velpandian T,Khokhar S,Dada T

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To identify risk factors for ocular graft-versus-host disease (oGVHD) in children with graft-versus-host disease (GVHD). METHODS:This retrospective cohort study identified 38 children diagnosed with GVHD who underwent an ophthalmological examination. Survival to onset of oGVHD after transplant was analyzed usi...

journal_title：Cornea

authors： Hébert M,Archambault C,Doyon C,Ospina LH,Robert MC

更新日期：2021-01-18 00:00:00

abstract：PURPOSE:To describe the association of water exposure with contact lens (CL)-related disease and explore the guidelines regarding water exposure to CL wearers, provided by CL manufacturing industry, global public health, and CL-related professional associations. METHODS:A review of the literature was conducted by sear...

journal_title：Cornea

authors： Arshad M,Carnt N,Tan J,Ekkeshis I,Stapleton F

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...

journal_title：Cornea

authors： Kadar T,Dachir S,Cohen M,Gutman H,Cohen L,Brandeis R,Horwitz V,Amir A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Patients undergoing primary pterygium excision with autologous conjunctival autograft and human tissue adhesive in New Zealand, currently receive subconjunctival anesthesia with oral postoperative analgesia for pain. Our aim was to investigate the potential added benefit of intraoperative subtenon bupivacaine t...

journal_title：Cornea

authors： Bhikoo R,Hughes K,Vather R,Murphy C

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To evaluate the influence of incision size on dry eye symptoms in the small incision lenticule extraction (SMILE) procedure. METHODS:Ninety-four eyes of 47 patients with myopia and/or myopic astigmatism who had undergone the SMILE procedure were enrolled in this study. The patients were divided into 3 groups a...

journal_title：Cornea

authors： Cetinkaya S,Gulmez M,Mestan E,Ucar F,Ali N

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To bioengineer a corneal surface replacement using ex vivo expanded, cultured corneal epithelial stem cells seeded on a matrix derived from amniotic membrane and use this bioengineered graft to manage difficult ocular surface disease. METHODS:Fourteen patients with ocular surface disease unresponsive to standa...

journal_title：Cornea

authors： Schwab IR,Reyes M,Isseroff RR

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:To report a case of epithelial ingrowth (downgrowth) occurring in a phakic corneal transplant patient after traumatic wound dehiscence with iris prolapse that was successfully eradicated with early surgical intervention. METHODS:Interventional case report of a 70-year-old monocular, phakic patient who develope...

journal_title：Cornea

authors： Nagra PK,Raber IM

更新日期：2003-03-01 00:00:00