Successful transplantation of bioengineered tissue replacements in patients with ocular surface disease.

abstract：PURPOSE:To evaluate trends in the acquisition, storage, and utilization of donated corneal tissue in New Zealand, 2000 to 2009. METHODS:The New Zealand National Eye Bank records were analyzed for the decade January 2000 to December 2009. Variables analyzed included donor demographics (age, sex, and ethnicity), donor s...

journal_title：Cornea

authors： Cunningham WJ,Moffatt SL,Brookes NH,Twohill HC,Pendergrast DG,Stewart JM,McGhee CN

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To study the expression of toll-like receptors (TLRs) in healthy corneas and corneas with active or nonactive herpetic stromal keratitis (HSK). METHODS:Eight corneas with HSK (including 5 active and 3 nonactive cases) and 8 healthy corneas were evaluated for TLR1-10 mRNA by reverse transcription-polymerase cha...

journal_title：Cornea

authors： Jin X,Qin Q,Chen W,Qu J

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:We standardized quality-controlled cord blood serum (CBS)-based eye drops and evaluated the efficacy of 1-month CBS treatment in the healing of diseased corneal epithelium in severe dry eye (DE) patients. METHODS:Seventeen graft-versus-host disease (GVHD) and 13 Sjogren syndrome patients with severe persistent...

journal_title：Cornea

authors： Versura P,Profazio V,Buzzi M,Stancari A,Arpinati M,Malavolta N,Campos EC

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:This study was designed to study an alternative technique of lamellar separation of corneal layers for therapeutic keratoplasty in place of an en bloc removal of host corneal button in eyes with perforated corneal ulcers with pseudocornea. METHODS:Twelve eyes with perforated corneal ulcers with pseudocornea in...

journal_title：Cornea

authors： Vajpayee RB,Singhvi A,Sharma N,Sinha R

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:The efficacy of gene therapy using nonviral vector based on polyplex micelle has been studied against corneal neovascularization in mice. METHODS:A block copolymer, poly(ethylene glycol) (PEG)-block-polycation carrying ethylenediamine units in the side chain (PEG-b-P[Asp(DET)]), was prepared. PEG-b-P[Asp(DET)]...

journal_title：Cornea

authors： Iriyama A,Usui T,Yanagi Y,Amano S,Oba M,Miyata K,Nishiyama N,Kataoka K

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of corneal cross-linking (CXL; riboflavin/ultraviolet A) as a simple therapy for Acanthamoeba keratitis. METHODS:Twenty rabbits were systemically anesthetized and the stroma of their right corneas was inoculated with a suspension of Acanthamoeba. Rabbits were divided into 2 groups: one...

journal_title：Cornea

authors： Berra M,Galperín G,Boscaro G,Zarate J,Tau J,Chiaradia P,Berra A

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To describe a new technique for donor insertion in cases of Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:This is a retrospective case series study of a novel method to introduce the donor tissue in DSAEK. This is a report of 16 cases that underwent the DSAEK procedure. The surgical te...

journal_title：Cornea

authors： Sarnicola V,Toro P

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To investigate the pachymetric changes of collagen cross-linking in corneas with edema because of endothelial dysfunction. METHODS:Interventional case series included 25 eyes of 25 consecutive patients with corneal edema for at least 4 months related to Fuchs endothelial dystrophy, corneal graft failure, and p...

journal_title：Cornea

authors： Cordeiro Barbosa MM,Barbosa JB Jr,Hirai FE,Hofling-Lima AL

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:To develop and measure the uptake of a local guideline for herpes simplex keratitis (HSK) and to standardize initial antiviral therapy in Australia. METHODS:The Registered Nurses' Association of Ontario Toolkit: "Implementation of Best Practice Guidelines" was used to develop, implement, and evaluate the guide...

journal_title：Cornea

authors： Cabrera-Aguas M,Kerdraon Y,Symes RJ,McCluskey P,Samarawickrama C,Rawlinson W,Watson SL

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to establish a new rhesus monkey model of severe dry eye. METHODS:A total of 8 rhesus monkeys were used for the study. Four monkeys had their main lacrimal gland and nictitating membrane surgically removed (group 1). Another 4 monkeys had a similar surgery with further application of ...

journal_title：Cornea

authors： Qin Y,Tan X,Zhang Y,Jie Y,Labbe A,Pan Z

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To describe cataract extraction and intraocular lens placement in a patient with an existing Type I Boston keratoprosthesis. METHODS:Case report to describe the surgical technique used to remove a cataract that developed after Boston keratoprosthesis placement. RESULTS:Extracapsular cataract extraction by usi...

journal_title：Cornea

authors： Harissi-Dagher M,Colby KA

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:To describe the clinical characteristics, diagnosis, treatment, and visual outcome of 61 cases of Fusarium keratitis in Mexico. METHODS:Retrospective, comparative study of 61 patients with clinically and culture-confirmed Fusarium keratitis, who were attended at an eye hospital in Mexico City from 1981 to 2001...

journal_title：Cornea

authors： Pérez-Balbuena AL,Vanzzini-Rosano V,Valadéz-Virgen Jde J,Campos-Möller X

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To describe the association of water exposure with contact lens (CL)-related disease and explore the guidelines regarding water exposure to CL wearers, provided by CL manufacturing industry, global public health, and CL-related professional associations. METHODS:A review of the literature was conducted by sear...

journal_title：Cornea

authors： Arshad M,Carnt N,Tan J,Ekkeshis I,Stapleton F

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:Light reflex from the cornea and tear film as contributors to beautiful eyes ("eye sparkling") are reviewed. METHODS:A systematic literature review was conducted using "Purkinje-Sanson image," "corneal light reflex," "corneal topography," "corneal wavefront aberration," and "tear interference image" as search ...

journal_title：Cornea

authors： Goto E

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To evaluate the reliability between pneumatonometry intraocular pressure (IOP) measurement in different scleral locations and corneal IOP in a penetrating keratoplasty (PK) setting. Our aim is to validate a method that can potentially be used for patients with keratoprostheses. METHODS:This is a prospective ob...

journal_title：Cornea

authors： Magalhaes OA,Aldave AJ

更新日期：2017-10-01 00:00:00

abstract：:Streptococcal infections are an important cause of corneal ulcers, endophthalmitis, conjunctivitis, and dacryocystitis. We retrospectively reviewed 53 ocular streptococcal infections diagnosed and followed at Wills Eye Hospital between January 1, 1984, and July 1, 1986. Corneal ulcers (23 of 53; 43%) and endophthalmit...

journal_title：Cornea

authors： Jones S,Cohen EJ,Arentsen JJ,Laibson PR

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To investigate the safety of intracameral injection of minimum bactericidal concentration (MBC) of povidone iodine (PI) on the corneal endothelium in a rabbit model as a proposed method of prophylaxis against postoperative endophthalmitis. METHODS:We included 32 New Zealand white rabbits in the study. Twenty-f...

journal_title：Cornea

authors： ElKitkat RS,Ebeid WM,Habib EK,Shoukry Y

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Surgical management of advanced pellucid marginal degeneration is challenging. To correct both corneal thinning and induced corneal astigmatism, we propose a modified intrastromal lamellar sclero-keratoplasty. METHODS:Corneal thinning was mapped using perioperative optical coherence tomography (OCT). Then thro...

journal_title：Cornea

authors： Guindolet D,Petrovic A,Doan S,Cochereau I,Gabison EE

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To report the indications, long-term structural and functional outcomes, and prognostic factors for the success of penetrating and lamellar corneal patch grafts. METHODS:This is a retrospective analysis of 49 patients who underwent the corneal patch graft procedure over 8 years. The baseline, preoperative, and...

journal_title：Cornea

authors： Sharma S,Rathi A,Murthy SI,Trivedi M,Patel C,Mohamed A,Chaurasia S

更新日期：2020-09-29 00:00:00

abstract：PURPOSE:To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS:Interventional case report. RESULTS:A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retra...

journal_title：Cornea

authors： Gregory ME,Weir CR,Ramaesh K

更新日期：2010-05-01 00:00:00

abstract：:Primary graft failure is a rare but major complication of penetrating keratoplasty. An apparent clustering of four cases during a 1-month period led to a review of all 778 keratoplasties performed by nine surgeons at Massachusetts Eye and Ear Infirmary from July 1, 1986 to June 30, 1988. The objectives of this study w...

journal_title：Cornea

authors： Mead MD,Hyman L,Grimson R,Schein OD

更新日期：1994-07-01 00:00:00

abstract：PURPOSE:To investigate the distribution and relative level of expression of the receptor tyrosine kinases, epidermal growth factor receptor (EGFR), ErbB2 and ErbB3, in human ocular surface epithelia. METHODS:Immunofluorescent staining was performed to identify expression of the EGFR, ErbB2 and ErbB3 in the corneal, li...

journal_title：Cornea

authors： Liu Z,Carvajal M,Carraway CA,Carraway K,Pflugfelder SC

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To study alterations of the extracellular matrix (ECM) and basement membrane (BM) components in human keratoconus corneas. METHODS:Fifteen normal and 13 keratoconus corneas were characterized by immunofluorescence with antibodies to 23 ECM and BM components. RESULTS:Keratoconus staining patterns for posterior...

journal_title：Cornea

authors： Kenney MC,Nesburn AB,Burgeson RE,Butkowski RJ,Ljubimov AV

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:To study dry eye and analyze pathogenic factors in patients after cataract surgery. METHODS:A total of 37 patients (50 eyes) were studied by using a 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ25) and Ocular Surface Disease Index (OSDI) 3 days before and 1 week, 1 month, and 3 months a...

journal_title：Cornea

authors： Li XM,Hu L,Hu J,Wang W

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Our study fills the spatiotemporal gaps in dry eye disease (DED) epidemiology by using Google Trends as a novel epidemiological tool for geographically mapping DED in relation to environmental risk factors. METHODS:We used Google Trends to extract DED-related queries estimating users' intent from 2004 to 2019 ...

journal_title：Cornea

authors： Azzam DB,Nag N,Tran J,Chen L,Visnagra K,Marshall K,Wade M

更新日期：2020-11-06 00:00:00

abstract：PURPOSE:To report the case of a 67-year-old woman with a diagnosis of multiple myeloma (MM) and atypical corneal opacity as the first appearance. METHODS:The patient consulted an ophthalmologist regarding blurred vision that progressed gradually without any systemic symptoms. The corneal epithelium and anterior stroma...

journal_title：Cornea

authors： Nakatsukasa M,Sotozono C,Tanioka H,Shimazaki C,Kinoshita S

更新日期：2008-02-01 00:00:00

abstract：:Contact lens (CL) fitting carries the risk of transmitting infectious agents, including adenovirus and Pseudomonas. Therefore, a number of precautions must be observed to ensure safety in the office. Paramount among these is hand washing, both immediately after contact with a patient's eyes and again between patients....

journal_title：Cornea

authors： Cohen EJ

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To describe a surgical technique to achieve the desired plane during deep anterior lamellar keratoplasty (DALK) in eyes with Descemet membrane (DM) tears due to previous hydrops. METHODS:This was a prospective, consecutive, interventional case series of DALK in 12 keratoconic eyes with healed hydrops. Dissecti...

journal_title：Cornea

authors： Goweida MB,Sobhy M,Seifelnasr M,Liu C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:To report a case of intraocular lens (IOL) exchange performed 1 week after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:Describe the clinical findings and outcome of IOL exchange in an 80-year-old man with pseudophakic bullous keratopathy and retained Artisan (Ophtec BV, Groningen, th...

journal_title：Cornea

authors： Lapenna L,Kadyan A,Busin M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...

journal_title：Cornea

authors： Garcia DD,Shtein RM,Musch DC,Elner VM

更新日期：2009-10-01 00:00:00