Abstract:
PURPOSE:This study was designed to study an alternative technique of lamellar separation of corneal layers for therapeutic keratoplasty in place of an en bloc removal of host corneal button in eyes with perforated corneal ulcers with pseudocornea. METHODS:Twelve eyes with perforated corneal ulcers with pseudocornea in which therapeutic keratoplasty was planned were included in the study. A new technique was used in which the host corneal tissue was removed in layers by lamellar dissection started peripherally and proceeding centripetally with care taken to prevent perforation at the site of iris incarceration. After injection of viscoelastic into the anterior chamber with a 26-gauge needle entered tangentially, the deeper layer of the cornea was then gently dissected and peeled away from the iris tissue, with care not to avulse the fragile iris and the overlying fibrotic membrane. Adjunctive procedures were performed, and the donor tissue was secured over the host bed. RESULTS:A complete separation of the iris tissue from corneal button and the fibrous membrane was achieved in 9 eyes. In 3 eyes, iris was partly trimmed along with the fibrous membrane, because the membrane was totally adherent to the iris tissue. Eight patients required pupilloplasty. Apart from minimal bleeding, no other complication was encountered. At the end of 3 months, 9 of 12 grafts remained clear. CONCLUSIONS:Debulking and layer-by-layer removal of host corneal tissue is effective in preservation of iris while performing therapeutic keratoplasty in eyes with perforated corneal ulcers with pseudocornea.
journal_name
Corneajournal_title
Corneaauthors
Vajpayee RB,Singhvi A,Sharma N,Sinha Rdoi
10.1097/01.ico.0000177834.85507.28subject
Has Abstractpub_date
2006-01-01 00:00:00pages
44-6issue
1eissn
0277-3740issn
1536-4798pii
00003226-200601000-00008journal_volume
25pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To compare optical low-coherence reflectometry (OLCR) and ultrasound pachymetry in measuring corneal graft thickness in patients after keratoplasty. METHODS:We retrospectively measured the central graft thickness in 41 eyes of 41 patients with the OLCR pachymeter (Haag Streit, Koeniz, Switzerland) and the SP-2...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000248387.62637.12
更新日期:2007-02-01 00:00:00
abstract::The fellow normal-appearing eyes of 23 patients with unilateral aphakic bullous keratopathy were examined by wide-field specular microscopy and pachymetry. All patients had: pseudophakic or aphakic bullous keratopathy in one eye; unoperated fellow eye on no medication; no other ocular disease; and no endothelial gutta...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:This report describes a case of multiple myeloma that presented as bilateral eyelid ecchymoses and corneal crystals in the absence of widespread signs of systemic disease. METHODS:A 55-year-old man was found to have the sudden appearance of bilateral eyelid ecchymoses after he flexed 90 degrees at the waist. O...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000154381.13237.a3
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:The expression of peroxiredoxin 2 and vascular endothelial growth factor receptor 2 (VEGFR2) was detected in pterygium to investigate whether they are involved in the pathogenesis or recurrence of pterygium and to evaluate the association between peroxiredoxin 2 and VEGFR2 in pterygium. METHODS:Ten normal bulb...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001213
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:To report the use of excimer laser phototherapeutic keratectomy (PTK) in the treatment of corneal subepithelial nodular scarring in a child with Rothmund-Thomson syndrome (RTS), a form of ectodermal dysplasia. METHODS:A case report and review of the literature. RESULTS:Excimer laser PTK successfully treated t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200001000-00022
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819717f4
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:To describe a distinct and unusual superficial dendriform keratopathy that can be seen in postkeratoplasty eyes. METHOD:Three Caucasian women in their sixth decade of life were referred to the Corneal and External Disease Service at the University of California, Davis, and underwent penetrating keratoplasty fo...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:PURPOSE:To report eyes with keratoconus that progressed during pregnancy. METHODS:Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was docu...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182068adc
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to describe the clinical features of infectious scleritis with distinct inciting events and to analyze the factors associated with poor visual outcome. METHODS:We retrospectively reviewed the predisposing factors, clinical findings, isolated organisms, complications, and outcomes of p...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000174
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318041f0c0
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To examine the efficacy of corneal collagen cross-linking (CXL) for the treatment of keratoconus (KCN). METHODS:A systemic literature review and meta-analysis of ocular functional and structural parameters of patients with KCN undergoing cross-linking procedures were performed using PubMed and the web of scien...
journal_title:Cornea
pub_type: 杂志文章,meta分析,评审
doi:10.1097/ICO.0000000000000723
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/ICO.0b013e3182114661
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to establish a new rhesus monkey model of severe dry eye. METHODS:A total of 8 rhesus monkeys were used for the study. Four monkeys had their main lacrimal gland and nictitating membrane surgically removed (group 1). Another 4 monkeys had a similar surgery with further application of ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000085
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:Peters anomaly is the most common cause of congenital corneal opacities. Although conservative management is often ineffective except in mild cases, surgical intervention in the form of penetrating keratoplasty is fraught with unpredictability and often has unacceptable postoperative outcomes. As such, there is...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000001472
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the corneal thickness asymmetry indices in a large pool of patients with keratoconus derived using anterior segment optical coherence tomography (AS-OCT) in comparison with established Scheimpflug imaging-derived keratoconus classification indices. METHODS:Six specific ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000275
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To investigate the effects of diquafosol sodium (DQS) eye drops, a purinergic P2Y2 receptor agonist, on tear film stability in patients with unstable tear film (UTF). METHODS:Two prospective studies were conducted. One was an exploratory nonrandomized trial on 39 eyes with dry eye symptoms and short tear film ...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/ICO.0b013e3182930b1d
更新日期:2013-08-01 00:00:00
abstract::We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199209000-00010
更新日期:1992-09-01 00:00:00
abstract::A modified relaxing incision technique for postkeratoplasty astigmatism is described in this article. Following the initial, standard relaxing incision techniques, a planned spreading and recutting of the initial relaxing incision was performed at 1-3-week intervals following the initial surgery. The wound may be deep...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To investigate the pachymetric changes of collagen cross-linking in corneas with edema because of endothelial dysfunction. METHODS:Interventional case series included 25 eyes of 25 consecutive patients with corneal edema for at least 4 months related to Fuchs endothelial dystrophy, corneal graft failure, and p...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181c296c2
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:To determine whether glucocorticoids suppress corneal lymphatic vessel growth (lymphangiogenesis) or induce lymphatic vessel regression. METHODS:We measured human lymphatic endothelial cell proliferation and collagen-induced tubulogenesis in culture conditions with and without dexamethasone, a potent glucocort...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318213f39f
更新日期:2011-12-01 00:00:00
abstract::To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue stainin...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To report the clinical impact of conjunctivochalasis on the ocular surface by evaluating the effect of a new concept of conjunctivochalasis operation on the resolution of patients' symptoms and corneal epithelial damage. Also, the association of inflammation with conjunctivochalasis is examined. PATIENTS AND M...
journal_title:Cornea
pub_type: 临床试验,杂志文章
doi:10.1097/01.ico.0000178740.14212.1a
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To determine the intrastromal layer of corneal deposits in granular corneal dystrophy (GCD). DESIGN:Investigative case report. METHODS:A 32-year-old woman with bilateral decreased vision because of corneal deposits was examined with cross-sectional scans using optical coherence tomography (OCT). RESULTS:Vi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200404000-00009
更新日期:2004-04-01 00:00:00
abstract::The authors sought to determine whether adenovirus could infect human corneal epithelium in vivo. They reviewed the medical records of six patients with adenovirus-positive viral corneal cultures who were examined at the Bascom Palmer Eye Institute between March 21, 1986, and December 31, 1992. The six patients with a...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::Specular microscopy can provide a noninvasive morphologic analysis of the corneal endothelial cell layer from subjects enrolled in clinical trials. The analysis provides a measure of the endothelial cell physiologic reserve from aging, ocular surgical procedures, pharmaceutical exposure, and general health of the corn...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0b013e31815892da
更新日期:2008-01-01 00:00:00
abstract::Fresh and organ-culture preserved human corneas were examined for HLA-A,B,C (class I) and HLA-DR (class II) histocompatibility antigens using mouse monoclonal antibodies and an indirect immunofluorescence technique. HLA-A,B,C antigens were detected on epithelial cells and on keratocytes, but not on endothelial cells i...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:Corneal transplantation is the standard of care for pediatric corneal opacities, but little consensus exists on optimal surgical management. Our goal was to evaluate cross-sectional data of donor and recipient characteristics collected from eye banks providing tissue for pediatric corneal transplant cases to as...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001900
更新日期:2019-05-01 00:00:00
abstract::We report a case of Mycobacterium chelonae keratitis following corneal injury by a foreign body. Diagnosis was made by Ziehl-Neelsen staining and Löwenstein-Jensen culture of corneal scrapings. On the basis of the in vitro susceptibility testing, the patient was treated with topical fortified amikacin. Given the lack ...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:To study the factors affecting the time to onset of ocular graft-versus-host disease (GVHD) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:A retrospective chart review of 200 patients with ocular GVHD was performed to evaluate the association between various do...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000340
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002371
更新日期:2020-09-01 00:00:00