Abstract:
PURPOSE:To report eyes with keratoconus that progressed during pregnancy. METHODS:Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was documented with changes in refraction, corneal topography, and rigid gas-permeable lens fitting pattern. Patients with accompanying systemic and ocular diseases associated with keratoconus, uncontrolled atopic disease, and eye rubbing were excluded. RESULTS:Mean increase in spherical equivalent refraction and simulated keratometry values were 1.4 ± 1.1 and 1.1 ± 0.8 diopters, respectively. In eyes wearing rigid gas-permeable lenses, increase in corneal apical touch and decrease in the base curve radius of the best-fitting contact lens were observed. CONCLUSIONS:Hormonal changes during pregnancy may affect corneal biomechanics negatively, and pregnancy may be a previously unrecognized risk factor for progression of keratoconus. To our knowledge, this is the first study showing pregnancy-induced keratoconus progression in patients with no accompanying disease.
journal_name
Corneajournal_title
Corneaauthors
Bilgihan K,Hondur A,Sul S,Ozturk Sdoi
10.1097/ICO.0b013e3182068adcsubject
Has Abstractpub_date
2011-09-01 00:00:00pages
991-4issue
9eissn
0277-3740issn
1536-4798journal_volume
30pub_type
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