Pregnancy-induced progression of keratoconus.

Abstract:

PURPOSE:To report eyes with keratoconus that progressed during pregnancy. METHODS:Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was documented with changes in refraction, corneal topography, and rigid gas-permeable lens fitting pattern. Patients with accompanying systemic and ocular diseases associated with keratoconus, uncontrolled atopic disease, and eye rubbing were excluded. RESULTS:Mean increase in spherical equivalent refraction and simulated keratometry values were 1.4 ± 1.1 and 1.1 ± 0.8 diopters, respectively. In eyes wearing rigid gas-permeable lenses, increase in corneal apical touch and decrease in the base curve radius of the best-fitting contact lens were observed. CONCLUSIONS:Hormonal changes during pregnancy may affect corneal biomechanics negatively, and pregnancy may be a previously unrecognized risk factor for progression of keratoconus. To our knowledge, this is the first study showing pregnancy-induced keratoconus progression in patients with no accompanying disease.

journal_name

Cornea

journal_title

Cornea

authors

Bilgihan K,Hondur A,Sul S,Ozturk S

doi

10.1097/ICO.0b013e3182068adc

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

991-4

issue

9

eissn

0277-3740

issn

1536-4798

journal_volume

30

pub_type

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