Optimizing Reading Tests for Dry Eye Disease.

Abstract:

PURPOSE:The aim of this study was to evaluate the visual function information obtained from multiple reading tests in a dry eye population. METHODS:In this case-control, single-center clinical research center-based study, 15 subjects with dry eye (mean age 65 years) and 10 normal subjects (mean age 40 years) were included. The Standardized Mini-Mental Examination was given to assure that subjects had normal cognitive function. Reading tests were both sentence based (Radner reading acuity test, reading contrast sensitivity test at a fixed print size, and menu-reading test) and paragraph based (Wilkins test and International Reading Speed Texts [IReST]). Wilkins and IReST tests were slightly modified to increase difficulty and visual stress. The main outcome measures were cognitive function, fatigue, dry eye symptoms, reading acuity, reading rate, and blink rate. RESULTS:Results showed significantly lower rates in all reading tests in subjects with dry eye than in normal subjects; in the age-matched subgroup, only the menu and contrast sensitivity tests lost significance. Fatigue was significantly related to the IReST test, both at normal and critical print sizes. Reflex tearing was monitored and shown to significantly decrease the reading rate. IReST scores were considered the baseline, and the percent change from one test to IReST was also used to differentiate dry eye and normal subjects. The blink rate, symptoms, and demographics were not significantly correlated with reading tests. CONCLUSIONS:Reading is a relevant end point that differentiates dry eye and normal subjects. This study evaluated a variety of reading tests for relevance as a measurable assessment of visual function in dry eye disease.

journal_name

Cornea

journal_title

Cornea

authors

Ousler GW 3rd,Rodriguez JD,Smith LM,Lane KJ,Heckley C,Angjeli E,Abelson MB

doi

10.1097/ICO.0000000000000490

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

917-21

issue

8

eissn

0277-3740

issn

1536-4798

journal_volume

34

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Ocular surface squamous neoplasia: a survey of changes in the standard of care from 2003 to 2012.

    abstract:PURPOSE:To evaluate the current standard of care of ophthalmologists who are likely to encounter ocular surface squamous neoplasia (OSSN) in their practices and to compare this with data gathered in 2003. METHODS:Invitations to a web-based survey were sent to members of the Ocular Microbiology and Immunology Group. In...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182a6ea6c

    authors: Adler E,Turner JR,Stone DU

    更新日期:2013-12-01 00:00:00

  • Recovery of Corneal Clarity After DMEK Followed by Rebubbling Versus Uneventful DMEK.

    abstract:PURPOSE:To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS:Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DM...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001554

    authors: Lazaridis A,Fydanaki O,Giallouros E,Georgalas I,Kymionis G,Sekundo W,Droutsas K

    更新日期:2018-07-01 00:00:00

  • Xerophthalmia because of dietary-induced vitamin a deficiency in a young Scottish man.

    abstract::Vitamin A deficiency causing xerophthalmia, although a major public health issue in sub-Saharan Africa, is rarely seen in people living in developed countries. In such cases, it is usually associated with severe malnutrition caused by intestinal disorders, such as celiac disease, pancreatitis, or extensive bowel surge...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181bd9ed5

    authors: Collins CE,Koay P

    更新日期:2010-07-01 00:00:00

  • Ocular Manifestations of Chordin-like 1 Knockout Mice.

    abstract:PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002371

    authors: Chen D,Liu Y,Shu G,Chen C,Sullivan DA,Kam WR,Hann S,Fowler M,Warman ML

    更新日期:2020-09-01 00:00:00

  • Mycobacterium chelonae keratitis: resolution after debridement and presoaked collagen shields.

    abstract::We report a case of Mycobacterium chelonae keratitis following corneal injury by a foreign body. Diagnosis was made by Ziehl-Neelsen staining and Löwenstein-Jensen culture of corneal scrapings. On the basis of the in vitro susceptibility testing, the patient was treated with topical fortified amikacin. Given the lack ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Lois N,Perez del Molino ML

    更新日期:1995-09-01 00:00:00

  • Effects of corneal cross-linking on contrast sensitivity, visual acuity, and corneal topography in patients with keratoconus.

    abstract:PURPOSE:To assess the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), visual acuity, and corneal topography investigating possible predictors of efficacy. METHODS:Sixty-eight eyes of 34 patients with progressive keratoconus were enrolled in this prospective study. CXL was performed in one...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31826672e2

    authors: Lamy R,Netto CF,Reis RG,Procopio B,Porco TC,Stewart JM,Dantas AM,Moraes HV Jr

    更新日期:2013-05-01 00:00:00

  • Treatment of Acanthamoeba keratitis by corneal cross-linking.

    abstract:PURPOSE:To evaluate the efficacy of corneal cross-linking (CXL; riboflavin/ultraviolet A) as a simple therapy for Acanthamoeba keratitis. METHODS:Twenty rabbits were systemically anesthetized and the stroma of their right corneas was inoculated with a suspension of Acanthamoeba. Rabbits were divided into 2 groups: one...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31825cea99

    authors: Berra M,Galperín G,Boscaro G,Zarate J,Tau J,Chiaradia P,Berra A

    更新日期:2013-02-01 00:00:00

  • Evaluation of endothelial mucin layer thickness after phacoemulsification with next generation ophthalmic irrigating solution.

    abstract:PURPOSE:To evaluate human corneal endothelial mucin layer thickness and ultrastructure after phacoemulsification and irrigation-aspiration with either next generation ophthalmic irrigating solution (NGOIS) or BSS PLUS. METHODS:Paired human corneas were mounted in an artificial anterior chamber, exposed to 3 minutes of...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31817313cb

    authors: Ghate DA,Holley G,Dollinger H,Bullock JP,Markwardt K,Edelhauser HF

    更新日期:2008-10-01 00:00:00

  • Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model.

    abstract:PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318041f08e

    authors: Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

    更新日期:2007-06-01 00:00:00

  • Endothelial keratoplasty without Descemet stripping after failed penetrating keratoplasty.

    abstract:PURPOSE:To evaluate outcomes of endothelial keratoplasty (EK) without Descemet membrane stripping for treatment of failed penetrating keratoplasty (PKP). METHODS:Retrospective cohort study of all eyes that underwent EK without Descemet membrane stripping for failed PKP at one institution between May 2008 and June 2010...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31823f8c59

    authors: Heitor de Paula F,Kamyar R,Shtein RM,Sugar A,Mian SI

    更新日期:2012-06-01 00:00:00

  • Infectious scleritis in Taiwan-a 10-year review in a tertiary-care hospital.

    abstract:PURPOSE:The aim of this study was to describe the clinical features of infectious scleritis with distinct inciting events and to analyze the factors associated with poor visual outcome. METHODS:We retrospectively reviewed the predisposing factors, clinical findings, isolated organisms, complications, and outcomes of p...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000174

    authors: Ho YF,Yeh LK,Tan HY,Chen HC,Chen YF,Lin HC,Chen SY,Hui-Kang D,Hsiao CH

    更新日期:2014-08-01 00:00:00

  • Intraocular lens exchange 1 week after descemet stripping automated endothelial keratoplasty.

    abstract:PURPOSE:To report a case of intraocular lens (IOL) exchange performed 1 week after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:Describe the clinical findings and outcome of IOL exchange in an 80-year-old man with pseudophakic bullous keratopathy and retained Artisan (Ophtec BV, Groningen, th...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181a1669e

    authors: Lapenna L,Kadyan A,Busin M

    更新日期:2010-02-01 00:00:00

  • Conjunctival epithelial cells cultured on human amniotic membrane fail to transdifferentiate into corneal epithelial-type cells.

    abstract:PURPOSE:Previous studies on the use of human amniotic membrane (HAM) in rabbit stem cell deficiency models have found the new epithelium growing over the HAM to express cornea-specific keratins (K3 and K12) in 40% of the cases, suggesting that HAM may have induced conjunctival epithelial cells to transdifferentiate int...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199903000-00013

    authors: Cho BJ,Djalilian AR,Obritsch WF,Matteson DM,Chan CC,Holland EJ

    更新日期:1999-03-01 00:00:00

  • Femtosecond laser-assisted inverted mushroom keratoplasty.

    abstract:PURPOSE:To evaluate best-corrected visual acuity (BCVA), refractive outcome, corneal topography, optical coherence tomography, and endothelial cell density 12 months after femtosecond laser-assisted inverted mushroom keratoplasty. METHODS:We performed a prospective study of a surgical case series of 5 patients undergo...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/QAI.0b013e31815bad0c

    authors: Cheng YY,Tahzib NG,van Rij G,van Cleynenbreugel H,Pels E,Hendrikse F,Nuijts R

    更新日期:2008-07-01 00:00:00

  • Posterior amorphous corneal dystrophy: ultrasound biomicroscopy findings in two cases.

    abstract::We present two cases of posterior amorphous corneal dystrophy in members of the same family. We correlated the clinical findings with refraction, topography, and ultrasound biomicroscopy (UBM). This is the first report of UBM findings in amorphous corneal dystrophy and we describe the depth of stromal opacification me...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200203000-00020

    authors: Castelo Branco B,Chalita MR,Casanova FH,Castelo Branco AB,Allemann N,de Freitas D

    更新日期:2002-03-01 00:00:00

  • The influence of age on the refractive index of the human corneal stroma resected using a mechanical microkeratome.

    abstract:PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:The VCH-1 was calibrated against a standard subjective Abbé refractometer using 7 randomly selected turbid semiliquid media. VCH...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31821008d5

    authors: Patel S,Alió JL,Amparo F,Rodriguez-Prats JL

    更新日期:2011-12-01 00:00:00

  • Correlation of corneal elevation with severity of keratoconus by means of anterior and posterior topographic analysis.

    abstract:PURPOSE:To investigate the severity of keratoconus in terms of corneal elevation differences with 2 different reference surfaces using topographic analysis. METHODS:Eighty-six eyes of 50 patients with keratoconus of various clinical stages (61 male and 25 female eyes) with mean age of 37.3 ± 11.6 years were evaluated....

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0B013E31823D1EE0

    authors: Ishii R,Kamiya K,Igarashi A,Shimizu K,Utsumi Y,Kumanomido T

    更新日期:2012-03-01 00:00:00

  • Preliminary in vitro evaluation of 2-octyl cyanoacrylate (Dermabond) to seal corneal incisions.

    abstract:OBJECTIVE:To compare the efficacy of Dermabond with conventional nylon sutures for sealing linear corneal incisions. METHODS:A keratome knife was used to create a 4-mm full-thickness linear corneal incision anterior to the limbal arcade in 20 fresh pig eyes. The incision was sealed with Dermabond tissue adhesive or cl...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000159734.75672.c4

    authors: Leung GY,Peponis V,Varnell ED,Lam DS,Kaufman HE

    更新日期:2005-11-01 00:00:00

  • Terrien marginal degeneration presenting with spontaneous corneal perforation.

    abstract:PURPOSE:To report spontaneous corneal perforation as a presenting sign of unilateral Terrien marginal degeneration in a young adult. METHODS:A 19-year-old woman presented with sudden loss of vision in her left eye of 1-day duration. Examination revealed superior corneal thinning with superficial vascularization and se...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000226367.41925.ab

    authors: Srinivasan S,Murphy CC,Fisher AC,Freeman LB,Kaye SB

    更新日期:2006-09-01 00:00:00

  • In vivo confocal microscopy and anterior segment optical coherence tomography in a case of alternaria keratitis.

    abstract:PURPOSE:To report a case of Alternaria alternata keratitis analyzed with in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (OCT). METHODS:A 68-year-old man with unilateral keratitis was evaluated using IVCM (Heidelberg Retina Tomograph II; Heidelberg, Germany) and anterior segment OC...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181dae1f3

    authors: Martone G,Pichierri P,Franceschini R,Moramarco A,Ciompi L,Tosi GM,Balestrazzi A

    更新日期:2011-04-01 00:00:00

  • Elevated immunoglobulin to tissue KLK11 in patients with Sjögren syndrome.

    abstract:PURPOSE:We have previously reported that mouse kallikrein (KLK) 22 in the lacrimal and salivary glands is an autoantigen that can induce primary Sjogren syndrome (SS) in rats. In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31826a1e2e

    authors: El Annan J,Jiang G,Wang D,Zhou J,Foulks GN,Shao H

    更新日期:2013-05-01 00:00:00

  • Descemet Membrane Endothelial Keratoplasty: Development of Contrast Sensitivity and Color Vision in Patients With Fuchs Endothelial Corneal Dystrophy.

    abstract:PURPOSE:To assess the developments in contrast sensitivity, color vision, and subjective perception after Descemet membrane endothelial keratoplasty (DMEK) in patients with Fuchs endothelial corneal dystrophy (FECD). METHODS:Included in this study were pseudophakic, unilateral DMEK patients with bilateral FECD having ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002320

    authors: Bayyoud T,Wilhelm H,Gelisken F,Martus P,Bartz-Schmidt KU,Thaler S

    更新日期:2020-07-01 00:00:00

  • Descemet stripping automated endothelial keratoplasty for spontaneous descemet membrane detachment in a patient with osteogenesis imperfecta.

    abstract:PURPOSE:To report the first use of Descemet stripping automated endothelial keratoplasty (DSAEK) for spontaneous Descemet membrane detachment in a patient with osteogenesis imperfecta (OI), keratoconus, and acute bullous keratopathy. METHODS:A case report of a 25-year-old man with OI and symptomatic unilateral bullous...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318225418b

    authors: Gorovoy MS,Gorovoy IR,Ullman S,Gorovoy JB

    更新日期:2012-07-01 00:00:00

  • Intraoperative mitomycin C 0.02% for pterygium: effect of duration of application on recurrence rate.

    abstract:PURPOSE:To compare the effect of a 3- and 5-minute intraoperative application of topical mitomycin C 0.02% on the recurrence of pterygium. METHODS:A comparative, prospective clinical design was used. The study population consisted of 134 consecutive patients with unilateral primary advanced pterygium (growth of 3 mm o...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章

    doi:10.1097/00003226-200303000-00003

    authors: Avisar R,Gaton DD,Loya N,Appel I,Weinberger D

    更新日期:2003-03-01 00:00:00

  • Inhibition of pathological corneal neovascularization by a small peptide derived from human apolipoprotein (a) Kringle V.

    abstract:PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000032

    authors: Wang Z,Zhao H,Ma JX,Xu X

    更新日期:2014-04-01 00:00:00

  • Epidemiological Association Between Systemic Diseases and Keratoconus in a Korean Population: A 10-Year Nationwide Cohort Study.

    abstract:PURPOSE:To investigate the association of systemic diseases with keratoconus in the general Korean population. METHODS:This is a nationwide population-based retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort database from 2002 to 2015, involving 1,108,369 individuals. ...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究

    doi:10.1097/ICO.0000000000002206

    authors: Lee HK,Jung EH,Cho BJ

    更新日期:2020-03-01 00:00:00

  • Acanthamoeba keratitis: a parasite on the rise.

    abstract:PURPOSE:To report a recent significant increase of the number of patients diagnosed with Acanthamoeba keratitis (AK) at Wills Eye Hospital between 2004 and 2005. To determine the risk factors, clinical characteristics, treatments, and outcomes of patients with AK. METHODS:Retrospective consecutive case series of 20 ey...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31805b7e63

    authors: Thebpatiphat N,Hammersmith KM,Rocha FN,Rapuano CJ,Ayres BD,Laibson PR,Eagle RC Jr,Cohen EJ

    更新日期:2007-07-01 00:00:00

  • Treatment of advanced acanthamoeba keratitis with deep lamellar keratectomy and conjunctival flap.

    abstract:PURPOSE:To describe whether deep lamellar keratectomy with a conjunctival flap is effective for the treatment of Acanthamoeba keratitis. METHODS:Two patients (three eyes) had at least a 4-week history of painful keratitis misdiagnosed as herpetic keratitis and bacterial keratitis. Both patients were started on multipl...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200210000-00014

    authors: Cremona G,Carrasco MA,Tytiun A,Cosentino MJ

    更新日期:2002-10-01 00:00:00

  • Conjunctival Melanoma: Outcomes Based on Age at Presentation in 629 Patients at a Single Ocular Oncology Center.

    abstract:PURPOSE:To investigate the clinical features and outcomes for conjunctival melanoma based on patient age. METHODS:A retrospective review of patients with conjunctival melanoma managed at a single tertiary referral center from April 18, 1974, to September 9, 2019. Clinical features and outcomes were compared by patient...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002449

    authors: Dalvin LA,Yaghy A,Vaidya S,Pacheco RR,Perez AL,Lally SE,Shields JA,Shields CL

    更新日期:2020-07-30 00:00:00

  • Topical autologous platelet-rich plasma eyedrops for acute corneal chemical injury.

    abstract:PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...

    journal_title:Cornea

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ICO.0b013e3182114661

    authors: Panda A,Jain M,Vanathi M,Velpandian T,Khokhar S,Dada T

    更新日期:2012-09-01 00:00:00