Abstract:
PURPOSE:To report a case of Alternaria alternata keratitis analyzed with in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (OCT). METHODS:A 68-year-old man with unilateral keratitis was evaluated using IVCM (Heidelberg Retina Tomograph II; Heidelberg, Germany) and anterior segment OCT (Visante OCT; Carl Zeiss Meditec, Dublin, CA). RESULTS:IVCM demonstrated the presence of small, round, hyperreflective cells surrounded by hyporeflective irregular areas and highly reflective dendritic shaped cells at the level of the epithelium. Stromal examination revealed many hypereflective filamentous structures, and some hyporeflective perpendicular lines and hyperreflective oval bodies were clearly visible along the filaments. Anterior segment OCT examination demonstrated a thickened cornea due to diffuse edema and an irregular corneal surface corresponding to the ulcer. There were hyperreflective areas beneath the epithelium representing the infiltrate. Microbiological examination of corneal scrapings demonstrated the presence of Alternaria alternata. After 1 month of antifungal treatment, IVCM demonstrated a significant reduction of the inflammatory cells and a hyperreflective scar-like tissue. Branching hyphal infiltrates were no longer present. OCT also documented the healing process and the complete recovery of the central and peripheral stromal thickness. CONCLUSIONS:IVCM and anterior segment OCT could be useful for the early diagnosis and treatment of fungal keratitis.
journal_name
Corneajournal_title
Corneaauthors
Martone G,Pichierri P,Franceschini R,Moramarco A,Ciompi L,Tosi GM,Balestrazzi Adoi
10.1097/ICO.0b013e3181dae1f3subject
Has Abstractpub_date
2011-04-01 00:00:00pages
449-53issue
4eissn
0277-3740issn
1536-4798journal_volume
30pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:Evaluation of contact lens-induced cytologic changes on the conjunctival surface. METHODS:Fifty eyes of 25 patients wearing soft or rigid gas-permeable contact lenses, and 50 healthy eyes of 25 control subjects were examined with conjunctival impression cytology. Of the patients wearing contact lenses, 40% did...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract:PURPOSE:To investigate the tear levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 in eyes after Boston keratoprosthesis type I (B-KPro) implantation and to correlate these markers with the established B-KPro prognostic categories. METHODS:Tear washes were co...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000893
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To evaluate the refractive, keratometric, and visual outcomes of a modified Ruiz procedure in patients with high astigmatism after penetrating keratoplasty (PKP). METHODS:Retrospective cohort study with 26 eyes of 24 patients. A modified Ruiz incision pattern was used. Two paired arcuate incisions, centered on...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318153f241
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318221ce7d
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To describe whether deep lamellar keratectomy with a conjunctival flap is effective for the treatment of Acanthamoeba keratitis. METHODS:Two patients (three eyes) had at least a 4-week history of painful keratitis misdiagnosed as herpetic keratitis and bacterial keratitis. Both patients were started on multipl...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200210000-00014
更新日期:2002-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the psychometric properties of the Keratoconus Outcomes Research Questionnaire (KORQ) in patients enrolled in the Save Sight Keratoconus Registry. METHODS:A cross-sectional study was conducted utilizing prospectively collected web-based registry data. The psychometric prop...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002169
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To compare the central corneal thickness (CCT) measurements measured by using the Pentacam Scheimpflug system with the CCT measured using ultrasound pachymetry (UP) and to compare the compatibility between the methods in normal, keratoconic, and cross-linked keratoconic corneas. METHODS:The study included 50 e...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002339
更新日期:2020-09-01 00:00:00
abstract::Twelve FITC-conjugated lectins were used to establish a reaction pattern with cellular and noncellular components in fresh-frozen and formalin-fixed paraffin sections of 11 normal human corneas. In frozen sections the epithelium demonstrated the most active lectin staining; keratocytes and endothelium stained to a les...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice. METHODS:A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000153555.82278.5b
更新日期:2005-07-01 00:00:00
abstract::This paper reviews the data of Frank et al. in the light of increasing concern over the safety of contact lenses used for extended wear. Relative risks were calculated for four types of contact lenses (CLs): extended wear soft, daily wear soft, rigid gas-permeable (RGP), and polymethylmethacrylate (PMMA) lenses--worn ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199010001-00024
更新日期:1990-01-01 00:00:00
abstract::We have utilized a radically new type of optical scanning microscope to study the full-thickness morphology of the intact cornea in an excised human eye bank eye and in freshly sacrificed rabbit eyes in situ. This technology enables one to study corneal morphology layer by layer in extremely thin sections, only distur...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:To compare endothelial cell analysis by the center and flex-center methods in corneas with guttae of differing severity and to determine the minimum countable cell number for using only the flex-center method. METHODS:Forty-seven eyes with corneal guttae and 50 age-matched normal controls were enrolled in the ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001334
更新日期:2017-12-01 00:00:00
abstract::This trial was a randomized, double-masked, crossover study during which patients with keratoconjunctivitis sicca underwent 6 weeks of treatment with either cyclosporine 1% ophthalmic ointment or placebo followed by 6 weeks of the alternative treatment. Washout periods using only unpreserved artificial tears preceded ...
journal_title:Cornea
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00003226-199307000-00007
更新日期:1993-07-01 00:00:00
abstract:PURPOSE:To evaluate the therapeutic effect of corneal cross-linking (CXL) in 2 cases of bullous keratopathy combined with corneal ulcer. METHODS:Two patients (2 eyes) were recruited for the sake of the study. Both suffered from bullous keratopathy and presented a gradually deteriorating, vision-threatening, central co...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181a81802
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:This study explored a new method for removing thermosensitive acrylic punctal plugs from lacrimal puncta. METHODS:A total of 14 dry eye patients (14 eyes), who required the removal of thermosensitive acrylic punctal plugs from the lacrimal puncta because of serious complications, were recruited. Among the 14 p...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000633
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To compare the corneal and aqueous penetration and pharmacokinetics of gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions and their effect on corneal reepithelialization after penetrating keratoplasty. METHODS:In this randomized, open-label, parallel-controlled study, corneal and aqueous penetration ...
journal_title:Cornea
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/ICO.0b013e3181608561
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:To evaluate the results of trocar-assisted, sutureless, scleral-fixated (SSF) intraocular lens (IOL) implantation combined with penetrating keratoplasty (PKP). METHODS:This study comprised 4 eyes (4 patients) undergoing trocar-assisted SSF-IOL implantation during PKP. The combined technique was performed in 3 ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000944
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To analyze the role of initial intraoperative intraocular pressure (IOP) in graft adhesion in Descemet membrane endothelial keratoplasty (DMEK) during early follow-up. METHODS:This retrospective, observational, single-center case series included 118 eyes from 118 consecutive patients treated between May and Ju...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001055
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To demonstrate the feasibility of Descemet membrane endothelial keratoplasty (DMEK) performed after previous penetrating keratoplasty (PK) failure and to describe primary outcomes. METHODS:Twenty-eight eyes of 28 patients who underwent DMEK after primary PK failure between January 2013 and November 2017 were i...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001834
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To describe a case of Beauveria bassiana keratitis and to discuss the management of this rare condition. METHODS:An 82-year-old woman underwent surgical repair of a graft wound dehiscence. Seven months later, shortly after the removal of sutures, the patient developed a fungal keratitis. B. bassiana was identi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200005000-00031
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:To review the clinical course, treatment, and visual outcomes of keratitis with endophthalmitis caused by the filamentary fungus Fusarium. METHOD:One hundred fifty-nine cases of Fusarium keratitis at Bascom Palmer Eye Institute between January 1, 1987 and August 21, 2000 were reviewed. Ten patients with cultur...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200305000-00004
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:Intrastromal corneal ring segments (ICRSs) are small arc-like implants that are being used increasingly as a minimally invasive treatment for patients with keratoconus. This study assessed the effectiveness of KeraRing implants, a type of ICRS, to treat keratoconus. METHODS:Retrospective case series descriptiv...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182215a15
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:In our report, we present a suspected case of donor-derived Acanthamoeba keratitis after deep anterior lamellar keratoplasty. To the authors' knowledge, there have been no confirmed cases of Acanthamoeba keratitis transmission through corneal transplantation. METHODS:Deep anterior lamellar keratoplasty was per...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002517
更新日期:2020-09-16 00:00:00
abstract:PURPOSE:We aimed to minimize the effect of ocular microfluctuations during videokeratoscopy to improve the qualitative and quantitative analysis of corneal topography. METHODS:A technique was developed to measure the tilt, displacement, and cyclotorsion in multiple videokeratographs from the same cornea. This informat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200205000-00003
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:To report a case of delayed bilateral Descemet's detachment with spontaneous resolution in one eye following successful treatment of the fellow eye. METHOD:Case report. RESULTS:A 78-year-old male who underwent uncomplicated bilateral cataract extraction with phacoemulsification developed delayed bilateral Des...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318197eef1
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:To evaluate and compare corneal thickness in normal and dry eyes. METHODS:The Orbscan corneal topography system was used to measure the corneal thickness at nine locations in the central and peripheral (superior, superonasal, nasal, inferonasal, inferior, inferotemporal, temporal, superotemporal) cornea in 38 ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199907000-00002
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:Meta-analysis to compare pterygium surgery outcomes using limbal conjunctival autograft (LCAG) and other techniques. METHODS:A comprehensive literature search was conducted through June 2011 using PubMed, Embase, and the Cochrane Registry to identify all randomized control trials reported so far, comparing the...
journal_title:Cornea
pub_type: 杂志文章,meta分析
doi:10.1097/ICO.0b013e31823cbecb
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To evaluate the stromal interface quality after femtosecond laser full lamellar cuts in gamma-irradiated corneas (VisionGraft sterile cornea) and to determine the limits of the cut depth using the VisionGraft as donor corneas for laser-assisted lamellar anterior keratoplasty. METHODS:Fourteen VisionGraft corne...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000614
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:Dry eye syndrome (DES) is a common eye disease caused by tear deficiency or excessive tear evaporation. Because the tear film layers play a major role in the pathogenesis of the evaporative dry eye, some previous articles have suggested the possible mechanism of dyslipidemia and DES. However, the previous resul...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002133
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the association between a Mediterranean dietary pattern (MeDi) and Vitamin D levels on dry eye syndrome (DES). METHODS:This was a cross-sectional study. Male patients seen in the Miami Veterans Affairs eye clinic with normal eyelid, corneal, and conjunctival anatomy were r...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000089
更新日期:2014-05-01 00:00:00