Abstract:
PURPOSE:To demonstrate the feasibility of Descemet membrane endothelial keratoplasty (DMEK) performed after previous penetrating keratoplasty (PK) failure and to describe primary outcomes. METHODS:Twenty-eight eyes of 28 patients who underwent DMEK after primary PK failure between January 2013 and November 2017 were included in this single-center retrospective study. Best spectacle-corrected visual acuity, endothelial cell density, and the recipient's central corneal thickness were recorded preoperatively and at 1, 3, and 6 months after surgery. RESULTS:The main indications for primary PK were keratoconus (32%), Fuchs dystrophy (18%), and pseudophakic bullous keratopathy (14%). After a 6-month follow-up, best spectacle-corrected visual acuity was significantly improved in 26 patients (93%) with a mean gain of +0.59 ± 0.47 LogMAR (P < 0.0004). Mean pachymetry reduction was 110 ± 108 μm (P < 0.00003) at 6 months. Mean endothelial cell density was 2016 ± 288 cells/mm (P < 0.006), (24% decrease compared with preoperative values). Graft detachment (>1/3) was observed in 14 cases (50%) and rebubbling was needed (100% effective) during the first 2 weeks after surgery. Elevated intraocular pressure was reported in 5 cases. No early graft rejections were reported. CONCLUSIONS:In case of previous PK failure, DMEK is an alternative treatment to re-PK. A longer follow-up to ensure the long-term viability of the graft is needed.
journal_name
Corneajournal_title
Corneaauthors
Pierné K,Panthier C,Courtin R,Mazharian A,Souedan V,Gatinel D,Saad Adoi
10.1097/ICO.0000000000001834subject
Has Abstractpub_date
2019-03-01 00:00:00pages
280-284issue
3eissn
0277-3740issn
1536-4798journal_volume
38pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:In a Strampelli osteo-odonto-keratoprosthesis, a patch of oral mucosa is frequently used to cover the ocular surface after implantation of an osteodental lamina into the eye. In many cases, gross modifications in the eye covering become apparent a few years later. The aim of this study was to investigate the hi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000170695.98078.42
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819c4e55
更新日期:2009-10-01 00:00:00
abstract::Viruses such as human immunodeficiency virus, herpes simplex virus, cytomegalovirus, hepatitis B, hepatitis C, and rabies can be transmitted to the recipient by corneal transplantation. Very few cases of rabies have been reported. Here we report two cases of rabies transmitted by the same donor. Both of the recipients...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199607000-00014
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:To describe cataract extraction and intraocular lens placement in a patient with an existing Type I Boston keratoprosthesis. METHODS:Case report to describe the surgical technique used to remove a cataract that developed after Boston keratoprosthesis placement. RESULTS:Extracapsular cataract extraction by usi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31815b7d69
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:To evaluate the influence of incision size on dry eye symptoms in the small incision lenticule extraction (SMILE) procedure. METHODS:Ninety-four eyes of 47 patients with myopia and/or myopic astigmatism who had undergone the SMILE procedure were enrolled in this study. The patients were divided into 3 groups a...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001782
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:Alkaline corneal epithelial wound closure rates in rabbit eyes were compared after topical applications of amniotic membrane suspension, autologous serum, or preservative-free artificial tears. METHODS:Thirty rabbits were divided into 3 randomization groups of 10 rabbits each. Central corneal alkali wound was ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318173138a
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:To assess frequency, associations, and outcomes of full air fill after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This retrospective study reviewed 368 consecutive DMEK cases performed to treat Fuchs dystrophy, bullous keratopathy, or failed keratoplasty. Primary outcomes were air bubble status...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001015
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To introduce an improved technique of pterygium surgery and to compare postoperative results between this technique and previous techniques. METHODS:In a retrospective survey, the records of 216 consecutive eyes with primary pterygium that underwent surgery by three different techniques were reviewed. The new ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200110000-00006
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To study the effect of topical cyclosporin A on herpetic stromal keratitis (HSK) in a mouse model. METHODS:The corneas of BALB/c mice were infected with herpes simplex type 1 virus. The mice were divided into 4 groups according to topical treatment methods: vehicle solution, 0.01% cyclosporin A, 0.1% cyclospor...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318160602d
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To report the clinical results of posterior lamellar keratoplasty (PLK) using predissected organ-cultured donor corneal tissue implanted after stripping of the Descemet membrane. METHODS:Twenty-two eyes of 22 patients in whom a PLK procedure was performed for pseudophakic bullous keratopathy and/or Fuchs endot...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000239002.92989.1a
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001257
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To analyze the role of initial intraoperative intraocular pressure (IOP) in graft adhesion in Descemet membrane endothelial keratoplasty (DMEK) during early follow-up. METHODS:This retrospective, observational, single-center case series included 118 eyes from 118 consecutive patients treated between May and Ju...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001055
更新日期:2017-01-01 00:00:00
abstract::Four patients had removal of their epikeratoplasty lenticules for unsatisfactory visual results. This was out of a consecutive series of 36 eyes. Three eyes were myopic and one was aphakic. In all four eyes, there was significant corneal steepening with an average increase in myopia of 2.4 diopters and an average incr...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:PURPOSE:To report bilateral epibulbar xanthomatous lesions in an adult with a normal serum lipid profile and no cutaneous or systemic features of a histiocytic disease. METHODS:Clinicopathologic report. RESULTS:A 44-year-old man presented with gradually enlarging yellow epibulbar masses in both eyes. The lesions had ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181a3c419
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to describe the clinicopathologic correlation of textural interface opacities (TIOs) in a Descemet stripping automated endothelial keratoplasty (DSAEK) donor button after its removal. METHODS:A 75-year-old woman underwent combined phacoemulsification with intraocular lens placement an...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000057
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To determine the safety and efficacy of amniotic membrane transplantation to restore and maintain a stable corneal epithelium and reduce ocular surface pain after surgical removal of band keratopathy arising from ocular causes. METHODS:Fifteen patients (16 eyes) from two centers with band keratopathy secondary...
journal_title:Cornea
pub_type: 杂志文章,多中心研究
doi:10.1097/00003226-200105000-00004
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:To describe a new technique for donor insertion in cases of Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:This is a retrospective case series study of a novel method to introduce the donor tissue in DSAEK. This is a report of 16 cases that underwent the DSAEK procedure. The surgical te...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31816f62bd
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To report 2 cases of ocular chemical burns associated with the use of a swim goggle antifog agent and to review the literature for this and similar antifog products. METHODS:Case reports and systematic review of the medical literature, material safety data, product safety reports, and consumer reviews. RESULT...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000000706
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:To determine the prevalence of herpes simplex virus type 1 (HSV-1) DNA in failed Descemet membrane stripping automated endothelial keratoplasty (DSAEK) grafts. METHODS:A retrospective interventional case series of patients with DSAEK graft failure treated at the New York Eye and Ear Infirmary between January 2...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31829b6d0c
更新日期:2013-09-01 00:00:00
abstract::Eleven patients with severe corneal disease have been operated with a collar-button-shaped keratoprosthesis and have been followed for 9-36 months. Two of the devices have been removed, but the remainder are securely in place. Six of the patients have benefitted substantially in terms of improved vision. The complicat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199405000-00004
更新日期:1994-05-01 00:00:00
abstract:PURPOSE:We aimed to investigate the possible association of proteoglycans with D-periodic collagen fibrils in the human cornea and sclera, using energy-filtering transmission electron microscopy (EF-TEM) and atomic force microscopy (AFM). METHODS:Human cornea and sclera were digested with keratanase to eliminate kerat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200108000-00019
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to report the successful medical management of 2 cases of late-onset endothelial keratoplasty-related stromal interface infections. METHODS:All cases of endothelial keratoplasty-related infections treated with intrastromal antifungal injections were compiled. The following information...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000192
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:We quantitated herpes simplex virus (HSV) DNA in tear film obtained from 2 patients who developed herpetic epithelial keratitis (HEK) during treatment with latanoprost and a beta-blocker. METHODS:The patient in case 1 is a 77-year-old woman with bilateral open-angle glaucoma who had been treated with latanopro...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200403000-00004
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:To determine whether glucocorticoids suppress corneal lymphatic vessel growth (lymphangiogenesis) or induce lymphatic vessel regression. METHODS:We measured human lymphatic endothelial cell proliferation and collagen-induced tubulogenesis in culture conditions with and without dexamethasone, a potent glucocort...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318213f39f
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To present outcomes of combined pars plana vitrectomy, silicone oil (SO) injection, and permanent keratoprosthesis (Kpro) procedure in prephthisical eyes. METHODS:All 3 patients were monocular with chronic severe hypotony, aphakia, and total corneal opacity in their vital eye. Preoperative visual acuity ranged...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181e289a4
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:Hyperglycemia in diabetes mellitus (DM) might induce changes in corneal biomechanics. Therefore, biomechanical properties of the cornea were measured using the ocular response analyzer and the Corvis ST. METHODS:In the study, 35 eyes of 35 diabetic patients were included. After an ophthalmological examination,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001879
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To report the outcome and the reversibility of refractive outcomes after intrastromal corneal ring segment (ICRS) explantation in patients with keratoconus treated with ICRS implantation and same-day collagen crosslinking (CXL). METHODS:This is a retrospective review of ICRS explantation in 3 eyes of 3 patient...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182a738ba
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To identify changing trends in penetrating keratoplasties (PKs) performed at the Hotel-Dieu Hospital in Paris between January 1980 and December 1999 and to explain the reasons for the changes. METHODS:We retrospectively reviewed 3,736 of the 3,836 PKs performed between January 1, 1980, and December 31, 1999, a...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200108000-00009
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of supratarsal triamcinolone injection in the treatment of superior limbic keratoconjunctivitis (SLK). METHODS:Forty eyes of 20 patients were diagnosed with SLK. All eyes with long-standing severe ocular irritation unresponsive to topical steroid and artificial tears were treated with ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318030d230
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To describe a case of bilateral peripheral ulcerative keratitis after Salmonella gastroenteritis. METHODS:Case report with description of treatment and outcome. RESULTS:The peripheral ulcerative keratitis gradually resolved in both eyes after appropriate systemic antibiotic therapy and local ocular care. CON...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199811000-00017
更新日期:1998-11-01 00:00:00