Abstract:
PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:The VCH-1 was calibrated against a standard subjective Abbé refractometer using 7 randomly selected turbid semiliquid media. VCH-1 was used to measure RI at the central midstroma immediately after lifting the flap in neophyte patients preselected for laser-assisted in situ keratomileusis. Surgical procedures continued as preplanned after measuring the RI; in binocular cases, measurements were taken from the right eye only. Flaps were created using a mechanical microkeratome. RESULTS:The VCH-1 was capable of measuring the RIs of all 7 turbid semiliquid media. The average RMS difference between RI estimates according to the VCH-1 and standard subjective Abbé refractometer was 0.003. The mean RI (± SD) of the stroma was 1.369 (± 0.008; range, 1.356-1.390), and the mean age (± SD) of the subjects was 33.7 years (± 8.86; range, 18-56 years). A significant linear correlation was found between age and RI. Least squares regression lines equating RI with age (x, years) was of the form: RI = 1.35711 + 0.00034x (r = +0.383, n = 36, P = 0.011). CONCLUSIONS:RI of the stroma in vivo has a tendency to be increased in older patients when the stroma is resected using a mechanical microkeratome.
journal_name
Corneajournal_title
Corneaauthors
Patel S,Alió JL,Amparo F,Rodriguez-Prats JLdoi
10.1097/ICO.0b013e31821008d5subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1353-7issue
12eissn
0277-3740issn
1536-4798journal_volume
30pub_type
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