Gemella haemolysans infectious crystalline keratopathy.


PURPOSE:To report a case of infectious crystalline keratopathy caused by Gemella haemolysans. METHODS:Observational case report. A 65-year-old woman underwent penetrating keratoplasty for contact lens-related Acanthamoeba keratitis and developed a nonhealing epithelial defect. Despite continued prophylaxis with topical gatifloxacin, small superficial stromal opacities were noted and cultured 6 months after penetrating keratoplasty. The opacities coalesced into a fine, crystalline keratopathy in the superficial stroma with persistent overlying epithelial defect. RESULTS:Culture results from corneal scraping showed more than 100 colonies of G. haemolysans. Topical vancomycin was instituted, with complete resolution of the crystalline keratopathy and epithelial defect over the next 2 months. CONCLUSIONS:G. haemolysans can be a causative organism of infectious crystalline keratopathy. This infection can arise in a postkeratoplasty patient despite prophylaxis with a fourth-generation fluoroquinolone.






Elmallah MK,Munir WM,Janda WM,Tu EY




Has Abstract


2006-12-01 00:00:00
















  • Randomized Control Trial on the Effectiveness of Collagen Cross-linking on Bullous Keratopathy.

    abstract:PURPOSE:To investigate the long-term effect and safety of collagen cross-linking (CXL) on patients with bullous keratopathy (BK) in a randomized control manner. It is, to our knowledge, the first randomized control study on the effect of CXL on BK. METHODS:Subjects were randomized to receive CXL as in the standard pro...


    pub_type: 杂志文章


    authors: Choy BNK,Ng ALK,Zhu MM,Liu CC,Xu S,Lai JSM

    更新日期:2020-11-01 00:00:00

  • Recurrence of corneal neovascularization associated with lipid deposition after subconjunctival injection of bevacizumab.

    abstract:PURPOSE:To report 7 cases of recurrent corneal neovascularization (NV) and lipid deposition after subconjunctival injection of bevacizumab for the treatment of corneal NV-induced lipid keratopathy. METHODS:We conducted a prospective interventional case series that included 20 eyes of chronic lipid keratopathy that rec...


    pub_type: 杂志文章


    authors: Chu HS,Chen TC,Hu FR,Chen WL

    更新日期:2013-11-01 00:00:00

  • Impression cytology study of conjunctival epithelial phenotypes on the healing ocular surface after pterygium excision.

    abstract:PURPOSE:To compare the process of conjunctival epithelial regeneration after three types of pterygium excision procedures. METHODS:Thirty-eight patients (45 eyes) with primary pterygium were randomly assigned to a bare-sclera procedure (group 1, 15 eyes of 12 patients), bare-sclera with intraoperative mitomycin C (MMC...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Tseng SH,Chen YT,Cheng HC,Huang FC,Lee SC,Chen FK

    更新日期:2001-04-01 00:00:00

  • Bilateral iridocorneal endothelial syndrome: case report and review of the literature.

    abstract::We present the case of a 47-year-old woman with bilateral iridocorneal endothelial syndrome. The iridocorneal endothelial syndrome has heretofore been considered a unilateral disorder. However, a review of the literature and examination of the patient presented in this report indicate that bilateral occurrence of the ...


    pub_type: 杂志文章,评审


    authors: Hemady RK,Patel A,Blum S,Nirankari VS

    更新日期:1994-07-01 00:00:00

  • Hemangiogenesis and lymphangiogenesis in corneal pathology.

    abstract:PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...


    pub_type: 杂志文章


    authors: Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

    更新日期:2012-01-01 00:00:00

  • Morphology of the Corneal Limbus Following Standard and Accelerated Corneal Collagen Cross-Linking (9 mW/cm2) for Keratoconus.

    abstract:PURPOSE:To evaluate the morphological features of the corneal limbus as measured by in vivo confocal microscopy (IVCM) following standard and accelerated corneal collagen cross-linking (CXL) for keratoconus. METHODS:Patients with progressive keratoconus scheduled to undergo standard CXL (group 1; 31 patients, 3 mW/cm,...


    pub_type: 杂志文章


    authors: Uçakhan ÖÖ,Bayraktutar B

    更新日期:2017-01-01 00:00:00

  • Conjunctival Melanoma: Outcomes Based on Age at Presentation in 629 Patients at a Single Ocular Oncology Center.

    abstract:PURPOSE:To investigate the clinical features and outcomes for conjunctival melanoma based on patient age. METHODS:A retrospective review of patients with conjunctival melanoma managed at a single tertiary referral center from April 18, 1974, to September 9, 2019. Clinical features and outcomes were compared by patient...


    pub_type: 杂志文章


    authors: Dalvin LA,Yaghy A,Vaidya S,Pacheco RR,Perez AL,Lally SE,Shields JA,Shields CL

    更新日期:2020-07-30 00:00:00

  • Risk Factors for Sporadic Diffuse Lamellar Keratitis After Microkeratome Laser-Assisted In Situ Keratomileusis: A Retrospective Large Database Analysis.

    abstract:PURPOSE:To determine the factors associated with sporadic diffuse lamellar keratitis (DLK) after microkeratome laser-assisted in situ keratomileusis (LASIK). METHODS:This large database retrospective study included consecutive cases of LASIK performed between 2007 and 2016 at Care-Vision Laser Centers, Tel-Aviv, Israe...


    pub_type: 杂志文章


    authors: Segev F,Mimouni M,Sela T,Munzer G,Kaiserman I

    更新日期:2018-09-01 00:00:00

  • Expression of the receptor tyrosine kinases, epidermal growth factor receptor, ErbB2, and ErbB3, in human ocular surface epithelia.

    abstract:PURPOSE:To investigate the distribution and relative level of expression of the receptor tyrosine kinases, epidermal growth factor receptor (EGFR), ErbB2 and ErbB3, in human ocular surface epithelia. METHODS:Immunofluorescent staining was performed to identify expression of the EGFR, ErbB2 and ErbB3 in the corneal, li...


    pub_type: 杂志文章


    authors: Liu Z,Carvajal M,Carraway CA,Carraway K,Pflugfelder SC

    更新日期:2001-01-01 00:00:00

  • Descemet-stripping automated endothelial keratoplasty by using suture for donor insertion.

    abstract:PURPOSE:To describe a new technique for donor insertion in cases of Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:This is a retrospective case series study of a novel method to introduce the donor tissue in DSAEK. This is a report of 16 cases that underwent the DSAEK procedure. The surgical te...


    pub_type: 杂志文章


    authors: Sarnicola V,Toro P

    更新日期:2008-08-01 00:00:00

  • Albumin in the cornea is oxidized by hydrogen peroxide.

    abstract::The action of hydrogen peroxide on soluble proteins of the rat cornea has been evaluated. Two major corneal proteins are found to be oxidized by 10 mM hydrogen peroxide. Protein sequence and antibody recognition has shown one of the proteins to be albumin. Treatment of pure rat or human albumin with hydrogen peroxide ...


    pub_type: 杂志文章


    authors: Zhu L,Crouch RK

    更新日期:1992-11-01 00:00:00

  • The prevalence of positive hepatitis B, hepatitis C, and HIV serology in cornea donors prescreened by medical and social history in Ontario, Canada.

    abstract:PURPOSE:To determine the prevalence of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) in the serum of cornea donors who had been previously screened by social and medical history by the Eye Bank of Canada, Ontario Division. METHOD:A retrospective examination of the donor records of the Ey...


    pub_type: 杂志文章


    authors: Armstrong SA,Gangam N,Chipman ML,Rootman DS

    更新日期:1997-09-01 00:00:00

  • A Novel Mobile Application for Preoperative and Intraoperative Assessments of Intrastromal Corneal Ring Segments Implantation for Keratoconus.

    abstract:PURPOSE:To develop a mobile app that allows photographs to be captured and edited under the overlay of images and projection of a protractor with 360 degrees axis markings, which enables the surgeon to accurately visualize the programmed and marked alignment where the intrastromal corneal ring segments (ICRS) will be i...


    pub_type: 杂志文章


    authors: Fernandes Dias FA,Fernandes Dias VJ,Carneiro CLB,Bernardes BG,Dutra BAL,Crispim Ribeiro J

    更新日期:2020-09-01 00:00:00

  • Remission of antiepiligrin (laminin-5) cicatricial pemphigoid after excision of gastric carcinoma.

    abstract:PURPOSE:To describe a case of antiepiligrin cicatricial pemphigoid with unusual ocular manifestations and its remission after surgical removal of gastric carcinoma. METHODS:We describe a 61-year-old Japanese man with antiepiligrin cicatricial pemphigoid. RESULTS:He presented with conjunctival injection and discharge ...


    pub_type: 杂志文章


    authors: Uchiyama K,Yamamoto Y,Taniuchi K,Matsui C,Fushida Y,Shirao Y

    更新日期:2000-07-01 00:00:00

  • Review of corneal endothelial specular microscopy for FDA clinical trials of refractive procedures, surgical devices, and new intraocular drugs and solutions.

    abstract::Specular microscopy can provide a noninvasive morphologic analysis of the corneal endothelial cell layer from subjects enrolled in clinical trials. The analysis provides a measure of the endothelial cell physiologic reserve from aging, ocular surgical procedures, pharmaceutical exposure, and general health of the corn...


    pub_type: 杂志文章,评审


    authors: McCarey BE,Edelhauser HF,Lynn MJ

    更新日期:2008-01-01 00:00:00

  • Cataract extraction after implantation of a type I Boston keratoprosthesis.

    abstract:PURPOSE:To describe cataract extraction and intraocular lens placement in a patient with an existing Type I Boston keratoprosthesis. METHODS:Case report to describe the surgical technique used to remove a cataract that developed after Boston keratoprosthesis placement. RESULTS:Extracapsular cataract extraction by usi...


    pub_type: 杂志文章


    authors: Harissi-Dagher M,Colby KA

    更新日期:2008-02-01 00:00:00

  • Effect of intravitreal ranibizumab on corneal endothelium in age-related macular degeneration.

    abstract:PURPOSE:To determine the effect of intravitreal injection of ranibizumab on the corneal endothelium in patients with choroidal neovascularization in age-related macular degeneration. METHODS:Observational prospective case series study. Fifty-two eyes of 52 consecutive patients (29 men, 23 women; age range, 61-80 years...


    pub_type: 杂志文章


    authors: Pérez-Rico C,Benítez-Herreros J,Castro-Rebollo M,Gómez-Sangil Y,Germain F,Montes-Mollón MA,Teus MA

    更新日期:2010-08-01 00:00:00

  • Primary Localized Conjunctival Amyloidosis Presenting Corneal Whorl-like Opacity Patterns.

    abstract:PURPOSE:To report an unusual case of corneal whorl-like opacity patterns in a patient of primary localized conjunctival amyloidosis. METHODS:Case report and review of literature. RESULTS:A 35-year old man with a case of primary localized conjunctival amyloidosis presented with corneal whorl-like opacity patterns and ...


    pub_type: 杂志文章


    authors: Sharma VK,Agarwal M,Tyagi A,Sati A

    更新日期:2020-07-01 00:00:00

  • OCT-derived comparison of corneal thickness distribution and asymmetry differences between normal and keratoconic eyes.

    abstract:PURPOSE:The aim of this study was to investigate the corneal thickness asymmetry indices in a large pool of patients with keratoconus derived using anterior segment optical coherence tomography (AS-OCT) in comparison with established Scheimpflug imaging-derived keratoconus classification indices. METHODS:Six specific ...


    pub_type: 杂志文章


    authors: Kanellopoulos AJ,Asimellis G

    更新日期:2014-12-01 00:00:00

  • A stepwise approach to donor preparation and insertion increases safety and outcome of Descemet membrane endothelial keratoplasty.

    abstract:PURPOSE:Lamellar techniques for selective replacement of diseased corneal structures have recently been improved. Descemet membrane endothelial keratoplasty (DMEK) allows the sole replacement of the endothelium--Descemet membrane layer (EDM). However, wide-spread use of DMEK is currently limited because of problems wit...


    pub_type: 杂志文章


    authors: Kruse FE,Laaser K,Cursiefen C,Heindl LM,Schlötzer-Schrehardt U,Riss S,Bachmann BO

    更新日期:2011-05-01 00:00:00

  • Adjustment of Intrastromal Corneal Ring Segments After Unsuccessful Implantation in Keratoconic Eyes.

    abstract:PURPOSE:To evaluate visual, refractive, and corneal topography outcomes in eyes with keratoconus that have undergone exchange/adjustment surgery with a new intrastromal corneal ring segment (ICRS) combination after unsuccessful visual and/or refractive outcomes after primary ICRS surgery. METHODS:A retrospective nonra...


    pub_type: 杂志文章


    authors: Monteiro T,Mendes JF,Faria-Correia F,Franqueira N,Madrid-Costa D,Alfonso JF

    更新日期:2018-02-01 00:00:00

  • Inhibition of human corneal epithelium with immunotoxin 454A12-rRA.

    abstract::We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...


    pub_type: 杂志文章


    authors: Fulcher SF,Foulks GN,Wilkerson M,Cobo LM,Jaffe GJ,Hatchell DL

    更新日期:1992-09-01 00:00:00

  • Topical drug formulations for prolonged corneal anesthesia.

    abstract:PURPOSE:Ocular local anesthetics currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect of the site 1 sodium channel blocker tetrodotoxin (TTX) on the duration of cornea...


    pub_type: 杂志文章


    authors: Wang L,Shankarappa SA,Tong R,Ciolino JB,Tsui JH,Chiang HH,Kohane DS

    更新日期:2013-07-01 00:00:00

  • A review of relative risks associated with four types of contact lenses.

    abstract::This paper reviews the data of Frank et al. in the light of increasing concern over the safety of contact lenses used for extended wear. Relative risks were calculated for four types of contact lenses (CLs): extended wear soft, daily wear soft, rigid gas-permeable (RGP), and polymethylmethacrylate (PMMA) lenses--worn ...


    pub_type: 杂志文章


    authors: Bailey CS

    更新日期:1990-01-01 00:00:00

  • Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas.

    abstract::After n-heptanol removal of the total corneal epithelium and a limbal lamellar keratectomy, 23 rabbit eyes developed features of limbal stem cell deficiency including conjunctival epithelial ingrowth, vascularization and chronic inflammation. One month later, 10 control eyes received a total keratectomy, and 13 experi...


    pub_type: 杂志文章


    authors: Kim JC,Tseng SC

    更新日期:1995-09-01 00:00:00

  • Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts.

    abstract:PURPOSE:To evaluate the efficacy of ultraviolet-corneal cross-linking (CXL) for treating infectious melting keratitis. METHODS:Five patients with infectious keratitis associated with corneal melting were treated with CXL at the outpatient departments of the Institut für Refraktive und Ophthalmo-Chirurgie and the eye h...


    pub_type: 杂志文章


    authors: Iseli HP,Thiel MA,Hafezi F,Kampmeier J,Seiler T

    更新日期:2008-06-01 00:00:00

  • Comparison of optical low-coherence reflectometry and ultrasound pachymetry in measuring corneal graft thickness.

    abstract:PURPOSE:To compare optical low-coherence reflectometry (OLCR) and ultrasound pachymetry in measuring corneal graft thickness in patients after keratoplasty. METHODS:We retrospectively measured the central graft thickness in 41 eyes of 41 patients with the OLCR pachymeter (Haag Streit, Koeniz, Switzerland) and the SP-2...


    pub_type: 杂志文章


    authors: Gaujoux T,Borderie VM,Yousfi H,Bourcier T,Touzeau O,Laroche L

    更新日期:2007-02-01 00:00:00

  • Recurrent Conjunctival Myofibrosarcoma Managed With Triple Application of Episcleral Brachytherapy.

    abstract:PURPOSE:To report a case of recurrent conjunctival myofibrosarcoma treated with wide surgical excision, cryotherapy, and triple sequential applications of episcleral brachytherapy. METHODS:A single case of recurrent conjunctival myofibrosarcoma. RESULTS:A 54-year-old man with a history of a renal transplant presented...


    pub_type: 杂志文章


    authors: Platt SM,Schoenfield L,Basti S,Bryar PJ,Goldblum JR,Singh A,Singh AD

    更新日期:2017-05-01 00:00:00

  • Validity of fluorexon disodium versus sodium fluorescein for use in Goldmann tonometry.

    abstract:PURPOSE:To evaluate the safety, validity, and comfort of 0.35% fluorexon disodium and 0.4% benoxinate (Flura-Safe) compared with the gold standard of 0.25% sodium fluorescein and 0.4% benoxinate for Goldmann applanation tonometry (GAT). METHODS:This was a double-masked, randomized, crossover clinical trial. Subjects r...


    pub_type: 杂志文章,随机对照试验


    authors: Ng LT,Tong JW,De Land PN

    更新日期:2006-07-01 00:00:00

  • Correlation between clinical in vivo confocal microscopic and ex vivo histopathologic findings of Salzmann nodular degeneration.

    abstract:PURPOSE:To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND). METHODS:A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PT...


    pub_type: 杂志文章


    authors: Meltendorf C,Bühren J,Bug R,Ohrloff C,Kohnen T

    更新日期:2006-07-01 00:00:00