Acanthamoeba keratitis: a parasite on the rise.

abstract：PURPOSE:To investigate the long-term effect and safety of collagen cross-linking (CXL) on patients with bullous keratopathy (BK) in a randomized control manner. It is, to our knowledge, the first randomized control study on the effect of CXL on BK. METHODS:Subjects were randomized to receive CXL as in the standard pro...

journal_title：Cornea

authors： Choy BNK,Ng ALK,Zhu MM,Liu CC,Xu S,Lai JSM

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:The shape and position of the eyelids affect corneal topography. This study evaluated preoperative and postoperative corneal topography in involutional ectropion of the lower eyelid. METHODS:Eighteen patients with unilateral involutional lower eyelid ectropion underwent ophthalmic examinations and corneal topo...

journal_title：Cornea

authors： Detorakis ET,Ioannakis K,Kozobolis VP

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effectiveness of punctal occlusion using hypromellose 2% in patients with dry eye. METHODS:In this prospective, randomized single-blinded clinical trial, we evaluated 76 eyes of 38 patients (36 women and 2 men) with dry eye secondary to rheumatic diseases. In each pati...

journal_title：Cornea

authors： Capita L,Chalita MR,dos Santos-Neto LL

更新日期：2015-02-01 00:00:00

abstract：:We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...

journal_title：Cornea

authors： Fulcher SF,Foulks GN,Wilkerson M,Cobo LM,Jaffe GJ,Hatchell DL

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:To describe the manual provocation test (MPT), a novel test for intermittent involutional entropion of the lower eyelid. METHODS:Retrospective review of patients with intermittent entropion who presented with ocular irritation and documented inward eyelid rotation by them or their referring physicians, but who...

journal_title：Cornea

authors： Tonk RS,Meyer DR

更新日期：2016-04-01 00:00:00

abstract：:The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...

journal_title：Cornea

authors： Azar DT,Chang JH,Han KY

更新日期：2012-11-01 00:00:00

abstract：:Corneal intraepithelial neoplasia (CIN) is the term applied by some authors to the spectrum of disease ranging from mild dysplasia to carcinoma in situ. Such lesions usually are associated with dysplastic or neoplastic processes at the limbus or adjacent conjunctiva; isolated corneal dysplasia is rare. Clinically, CIN...

journal_title：Cornea

authors： Brown HH,Glasgow BJ,Holland GN,Foos RY

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:To review ocular injuries secondary to airbag deployment that were seen in our institution and were reported in the literature. METHODS:Patients examined at our institution between 1997 and 2000 were evaluated for ocular injuries caused by airbags. A review of the medical literature using Medline was performed...

journal_title：Cornea

authors： Ball DC,Bouchard CS

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:We have previously reported that mouse kallikrein (KLK) 22 in the lacrimal and salivary glands is an autoantigen that can induce primary Sjogren syndrome (SS) in rats. In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a...

journal_title：Cornea

authors： El Annan J,Jiang G,Wang D,Zhou J,Foulks GN,Shao H

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To evaluate adhesion of Acanthamoeba trophozoites to different silicone hydrogel contact lens (SHCL) generations with and without multipurpose contact lens care solution (MPS) treatment. METHODS:Acanthamoeba lugdunensis L3a trophozoites were inoculated onto discs trimmed from SHCLs: first generation, Air Optix...

journal_title：Cornea

authors： Lee GH,Lee JE,Park MK,Yu HS

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To report the use of intracameral amphotericin B in the management of deep keratomycosis. METHODS:Four patients with deep keratomycosis unresponsive to conventional medical treatment underwent repeated intracameral injections of 5 microg amphotericin B in 0.1 mL 5% dextrose through a paracentesis. Three to 13 ...

journal_title：Cornea

authors： Kuriakose T,Kothari M,Paul P,Jacob P,Thomas R

更新日期：2002-10-01 00:00:00

abstract：:Salzmann's nodular degeneration is a rare, noninflammatory, slowly progressive, degenerative condition. Bluish-white nodules raised above the surface of the cornea characterize it. It has usually developed in corneas with a history of phlyctenulosis, trachoma, vernal keratoconjunctivitis, measles, scarlet fever, and v...

journal_title：Cornea

authors： Das S,Link B,Seitz B

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...

journal_title：Cornea

authors： Lee YC,Kim SY

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To compare corneal endothelial cell loss after cataract surgery by phacoemulsification and by Aqualase. METHODS:This was a prospective, randomized study of 75 eyes of 75 patients undergoing cataract surgery. Patients were randomly assigned to receive either phacoemulsification or Aqualase for cataract removal....

journal_title：Cornea

authors： Hu V,Hughes EH,Patel N,Whitefield LA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To characterize the clinical presentation of limbal stem cell deficiency (LSCD) associated with glaucoma surgeries. METHODS:This is a retrospective cross-sectional study of patients with LSCD and glaucoma who presented to the Stein Eye Institute at the University of California, Los Angeles, between 2009 and 20...

journal_title：Cornea

authors： Sun Y,Yung M,Huang L,Tseng C,Deng SX

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To establish a time-proven "gold standard" in modified osteoodontokeratoprosthesis (OOKP) surgery. METHODS:The OOKP is the procedure of choice for restoring sight in patients with corneal blindness caused by end-stage ocular surface disease not amenable to penetrating keratoplasty. Members of the OOKP Study Gr...

journal_title：Cornea

authors： Hille K,Grabner G,Liu C,Colliardo P,Falcinelli G,Taloni M,Falcinelli G

更新日期：2005-11-01 00:00:00

abstract：:Specular microscopy can provide a noninvasive morphologic analysis of the corneal endothelial cell layer from subjects enrolled in clinical trials. The analysis provides a measure of the endothelial cell physiologic reserve from aging, ocular surgical procedures, pharmaceutical exposure, and general health of the corn...

journal_title：Cornea

authors： McCarey BE,Edelhauser HF,Lynn MJ

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To describe a patient whose Descemet membrane detachment following deep lamellar keratoplasty failed to respond to 2 attempts at gas tamponade but later resolved spontaneously. METHODS:A 77-year-old woman with bilateral anterior corneal stromal scarring underwent a right deep lamellar keratoplasty with the Mel...

journal_title：Cornea

authors： Tu KL,Ibrahim M,Kaye SB

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To compare the central corneal thickness (CCT) measurements measured by using the Pentacam Scheimpflug system with the CCT measured using ultrasound pachymetry (UP) and to compare the compatibility between the methods in normal, keratoconic, and cross-linked keratoconic corneas. METHODS:The study included 50 e...

journal_title：Cornea

authors： Kosekahya P,Koc M,Yalcinsoy KO,Kocabas DO,Toker MI

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To investigate the changes in anterior and posterior corneal irregularity after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This retrospective study included 27 eyes of 23 patients who underwent DMEK and 27 eyes of age-matched healthy controls. Corneal irregularity indexes, surface regularity of...

journal_title：Cornea

authors： Oyakawa I,Hayashi T,Kobashigawa Y,Matsuzawa A,Takahashi H,Kato N

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:Evaluation of contact lens-induced cytologic changes on the conjunctival surface. METHODS:Fifty eyes of 25 patients wearing soft or rigid gas-permeable contact lenses, and 50 healthy eyes of 25 control subjects were examined with conjunctival impression cytology. Of the patients wearing contact lenses, 40% did...

journal_title：Cornea

authors： Adar S,Kanpolat A,Sürücü S,Ucakhan OO

更新日期：1997-05-01 00:00:00

abstract：:The present study describes biochemical and morphological differences of pseudophakic bullous keratopathy (PBK) corneas as compared with normal corneas. At the ultrastructural level, all PBK corneas studied had abnormal fibrillar material posterior to the Descemet's membrane. In addition, two of the six PBK buttons ha...

journal_title：Cornea

authors： Kenney MC,Chwa M

更新日期：1990-04-01 00:00:00

abstract：PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...

journal_title：Cornea

authors： Kadar T,Dachir S,Cohen M,Gutman H,Cohen L,Brandeis R,Horwitz V,Amir A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To report the outcomes of Boston keratoprosthesis (K-pro) type I implantation for congenital aniridia. METHODS:A retrospective review of the medical records of every patient with congenital aniridia who underwent Boston K-pro type I implantation at the University of Iowa Hospitals and Clinics from January 1, 2...

journal_title：Cornea

authors： Rixen JJ,Cohen AW,Kitzmann AS,Wagoner MD,Goins KM

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To demonstrate the role of intrinsic hyaluronic acid (HA) in the entrapment of inflammatory cells by amniotic membrane (AM) in vitro. METHODS:HA concentration in AM was analyzed by the sandwich protein binding assay, and the approximate molecular weight was measured by gel filtration chromatography. To localiz...

journal_title：Cornea

authors： Higa K,Shimmura S,Shimazaki J,Tsubota K

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...

journal_title：Cornea

authors： Shtein RM,Stahl RM,Saxe SJ,Mian SI

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. METHODS:Retrospective, descriptive, nonrandomized case series. RESULTS:Thirty-five eyes of 18 patients (14 cases from 6 families and 4 isolated cases) with diffuse posterior polymorphous corneal dys...

journal_title：Cornea

authors： Raber IM,Fintelmann R,Chhabra S,Ribeiro MP,Eagle RC Jr,Orlin SE

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Decorin is a small chondroitin sulfate proteoglycan that inhibits vascular endothelial cell migration and tube formation. Membrane type 1-matrix metalloproteinase (MT1-MMP) has been shown to be an important angiogenic enzyme in the cornea. We evaluated the specific role of MT1-MMP in decorin cleavage in the cor...

journal_title：Cornea

authors： Mimura T,Chang JH,Kim TI,Onguchi T,Kojima T,Sakimoto T,Azar DT

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To describe an impression cytology (IC) technique using a purpose-built, sterile, EYEPRIM IC device that can be coupled with a TRIzol reagent-based RNA extraction protocol to yield sufficient RNA for gene expression analysis. METHODS:IC samples using the EYEPRIM device were collected from the bulbar conjunctiv...

journal_title：Cornea

authors： Ganesalingam K,Ismail S,Craig JP,Sherwin T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:Microbiological contamination is a common cause for elimination of organ-cultured donor corneas. The aims of the present study were to analyze contamination rates and identify risk factors for contamination. METHODS:Retrospectively, the contamination rates of 4546 organ-cultured corneas and the causative speci...

journal_title：Cornea

authors： Linke SJ,Fricke OH,Eddy MT,Bednarz J,Druchkiv V,Kaulfers PM,Wulff B,Püschel K,Richard G,Hellwinkel OJ

更新日期：2013-02-01 00:00:00