Review of corneal endothelial specular microscopy for FDA clinical trials of refractive procedures, surgical devices, and new intraocular drugs and solutions.

abstract：PURPOSE:To report that spontaneous postkeratoplasty wound dehiscence or gaps caused by suture removal may occur years after penetrating and deep lamellar keratoplasty. METHODS:We retrospectively reviewed the medical records of 667 keratoplasty patients (890 eyes). This study included 8 eyes of 8 patients (3 men and 5 ...

journal_title：Cornea

authors： Fujii S,Matsumoto Y,Fukui M,Fujitake J,Kawakita T,Shimmura S,Tsubota K

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:We report 2 cases in which cataract extraction with a foldable acrylic toric intraocular lens (IOL) implantation was used to correct (irregular) corneal astigmatism in patients with keratoconus and cataract. METHODS:Case 1 was a 78-year-old man with cataract and keratoconus in the left eye. He underwent phacoe...

journal_title：Cornea

authors： Visser N,Gast ST,Bauer NJ,Nuijts RM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:To report a case of corneal infection with Chrysosporium parvum, a filamentous fungus usually associated with pulmonary infections. METHODS:A 43-year-old Saudi man had a corneal stromal infiltrate and perforation of his left eye. He was treated with a therapeutic penetrating keratoplasty and topical and system...

journal_title：Cornea

authors： Wagoner MD,Badr IA,Hidayat AA

更新日期：1999-09-01 00:00:00

abstract：PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...

journal_title：Cornea

authors： Giannaccare G,Buzzi M,Fresina M,Velati C,Versura P

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To compare the visual outcomes and postoperative complications in patients undergoing penetrating keratoplasty (PKP) in 1 eye followed by Descemet membrane endothelial keratoplasty (DMEK) in their fellow eye. METHODS:A retrospective analysis of 11 patients, who underwent a PKP procedure first in 1 eye and then...

journal_title：Cornea

authors： Maier AK,Gundlach E,Gonnermann J,Klamann MK,Eulufi C,Bertelmann E,Joussen AM,Torun N

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to describe the clinical features of infectious scleritis with distinct inciting events and to analyze the factors associated with poor visual outcome. METHODS:We retrospectively reviewed the predisposing factors, clinical findings, isolated organisms, complications, and outcomes of p...

journal_title：Cornea

authors： Ho YF,Yeh LK,Tan HY,Chen HC,Chen YF,Lin HC,Chen SY,Hui-Kang D,Hsiao CH

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To assess the long-term clinical course of dry eye in patients with chronic graft-versus-host disease (cGVHD). METHODS:A prospective case series of 49 patients with cGVHD was conducted. Complete history and ophthalmic examination were performed at baseline and at 36 months (range, 26-53). All patients received...

journal_title：Cornea

authors： Sáles CS,Johnston LJ,Ta CN

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To describe cataract extraction and intraocular lens placement in a patient with an existing Type I Boston keratoprosthesis. METHODS:Case report to describe the surgical technique used to remove a cataract that developed after Boston keratoprosthesis placement. RESULTS:Extracapsular cataract extraction by usi...

journal_title：Cornea

authors： Harissi-Dagher M,Colby KA

更新日期：2008-02-01 00:00:00

abstract：:We performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. There were 82 positive cultures (39%), and the most common pathogen was Staphylococcus epidermidis, with 24 positive cultures (30%). Ten of these (42%) were resistant to genta...

journal_title：Cornea

authors： Mathers WD,Lemp MA

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To describe the management and outcome of an ocular surface alkali burn in the setting of previous laser in situ keratomileusis (LASIK). METHODS:This is a case report and review of relevant literature. RESULTS:A 25-year-old man with a history of LASIK presented 4 weeks after a sodium hydroxide splash to his l...

journal_title：Cornea

authors： Witsberger EM,Patel SV

更新日期：2020-12-03 00:00:00

abstract：PURPOSE:To describe a case of Lisch epithelial corneal dystrophy (LECD) and present its unique characteristics on high-resolution optical coherence tomography (HR-OCT). METHODS:A 78-year-old man with whorled corneal epithelial opacities in the right eye was referred for the evaluation of ocular surface squamous neopla...

journal_title：Cornea

authors： Pole C,Sise A,Joag M,Galor A,Bermudez-Magner JA,Dubovy S,Karp CL

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate the anterior segment parameters in patients with osteogenesis imperfecta (OI) compared with healthy control subjects. METHODS:Seventeen patients with OI and 19 age-matched healthy controls were included into this cross-sectional case-control study. Corneal topographic, topometric and Belin-Ambrósio...

journal_title：Cornea

authors： Keleş A,Doğuizi S,Şahin NM,Koç M,Aycan Z

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To describe whether deep lamellar keratectomy with a conjunctival flap is effective for the treatment of Acanthamoeba keratitis. METHODS:Two patients (three eyes) had at least a 4-week history of painful keratitis misdiagnosed as herpetic keratitis and bacterial keratitis. Both patients were started on multipl...

journal_title：Cornea

authors： Cremona G,Carrasco MA,Tytiun A,Cosentino MJ

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...

journal_title：Cornea

authors： Chen D,Liu Y,Shu G,Chen C,Sullivan DA,Kam WR,Hann S,Fowler M,Warman ML

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of Descemet membrane endothelial keratoplasty (DMEK) performed after previous penetrating keratoplasty (PK) failure and to describe primary outcomes. METHODS:Twenty-eight eyes of 28 patients who underwent DMEK after primary PK failure between January 2013 and November 2017 were i...

journal_title：Cornea

authors： Pierné K,Panthier C,Courtin R,Mazharian A,Souedan V,Gatinel D,Saad A

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To assess the efficacy and safety of intraductal meibomian gland probing in patients with obstructive meibomian gland dysfunction who experienced little improvement with eyelid warming, massage, or artificial tears. METHODS:Forty-nine patients with obstructive meibomian gland dysfunction were randomly divided ...

journal_title：Cornea

authors： Ma X,Lu Y

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To examine the immediate effect of ocular rubbing on corneal topography. METHODS:Corneal topography and analysis were performed before, immediately after, and 5 minutes after eyelid rubbing in 29 volunteers without ocular disease. RESULTS:The surface regularity index increased from a baseline of 0.24 to 0.91 ...

journal_title：Cornea

authors： Mansour AM,Haddad RS

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:To present a case of acute idiopathic endotheliitis occurred early after corneal collagen cross-linking (CXL) for progressive keratoconus, and to discuss possible risk factors, causes, and other similar complications in the literature. METHODS:A 24-year-old woman with bilateral keratoconus underwent a corneal ...

journal_title：Cornea

authors： Gumus K

更新日期：2014-06-01 00:00:00

abstract：:The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels were present in the periphery of debrided corneas at 1 h (90.12 +/- ...

journal_title：Cornea

authors： O'Day DM,Smith R,Stevens JB,Williams TE,Robinson RD,Head WS

更新日期：1991-09-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of plasma rich in growth factors (PRGF) for the treatment of moderate/severe dry eye. METHODS:PRGF treatment was administered to 16 patients who had moderate/severe dry eye diagnosed and who had not responded previously to other standard treatments. We quantified several growth factors...

journal_title：Cornea

authors： López-Plandolit S,Morales MC,Freire V,Grau AE,Durán JA

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of autologous serum (AS) eye drops combined with punctal plugs (PPs) in patients with Sjögren syndrome (SS)-related dry eye. METHODS:A retrospective clinical study was performed in patients with dry eye caused by SS. We evaluated the Schirmer test value, tear breakup time (t...

journal_title：Cornea

authors： Liu Y,Hirayama M,Cui X,Connell S,Kawakita T,Tsubota K

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS:Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DM...

journal_title：Cornea

authors： Lazaridis A,Fydanaki O,Giallouros E,Georgalas I,Kymionis G,Sekundo W,Droutsas K

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To report a case of recurrent conjunctival myofibrosarcoma treated with wide surgical excision, cryotherapy, and triple sequential applications of episcleral brachytherapy. METHODS:A single case of recurrent conjunctival myofibrosarcoma. RESULTS:A 54-year-old man with a history of a renal transplant presented...

journal_title：Cornea

authors： Platt SM,Schoenfield L,Basti S,Bryar PJ,Goldblum JR,Singh A,Singh AD

更新日期：2017-05-01 00:00:00

abstract：:Although corneal epithelial stem cells (SCs) are located at the limbus between the cornea and the conjunctiva, not all limbal basal epithelial cells are SCs. Using 2 dispase digestions to remove different amounts of limbal basal epithelial cells for cross-sections, flat mounts, and cytospin preparations, double immuno...

journal_title：Cornea

authors： Hayashida Y,Li W,Chen YT,He H,Chen SY,Kheirkah A,Zhu YT,Matsumoto Y,Tseng SC

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To determine the effectiveness of prophylactic fluoroquinolone treatment against staphylococci in a rabbit keratitis model. METHODS:Prophylactic ciprofloxacin or ofloxacin was applied as one topical drop 15 minutes before infection or as one drop at three time points (19, 17, and 15 minutes) before infection. ...

journal_title：Cornea

authors： Dajcs JJ,Moreau JM,Thibodeaux BA,Traidej M,Austin MS,Marquart ME,Stroman DW,O'Callaghan RJ

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To review data on malpractice claims related to refractive surgery to identify common allegations and injuries and financial outcomes. METHODS:The WestlawNext database was reviewed for all malpractice lawsuits/settlements related to refractive eye surgery. Data evaluated included patient demographics, type of ...

journal_title：Cornea

authors： Custer BL,Ballard SR,Carroll RB,Barnes SD,Justin GA

更新日期：2017-10-01 00:00:00

abstract：:Salzmann's nodular degeneration is a rare, noninflammatory, slowly progressive, degenerative condition. Bluish-white nodules raised above the surface of the cornea characterize it. It has usually developed in corneas with a history of phlyctenulosis, trachoma, vernal keratoconjunctivitis, measles, scarlet fever, and v...

journal_title：Cornea

authors： Das S,Link B,Seitz B

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:To determine the proportion of patients who were dispensed amantadine and diagnosed with corneal edema or Fuchs dystrophy within specified time frames. METHODS:Postmarketing surveillance study. The national Veterans Health Administration pharmacy and clinical databases were used to identify a cohort of veteran...

journal_title：Cornea

authors： French DD,Margo CE

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:To assess the surgical and clinical outcomes of anterior lamellar keratoplasty using anterior corneal buttons from Descemet stripping automated endothelial keratoplasty (DSAEK) donor tissue. METHODS:Retrospective data from 8 patients with unilateral limbal dermoids, treated between February 2011 and January 20...

journal_title：Cornea

authors： Wu KI,Chu HS,Pai AS,Hou YC,Lin SY,Chen WL,Hu FR

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To describe the incidence and prevalence of glaucoma in a patient population with severe ocular surface disease (OSD). METHODS:A retrospective case series was compiled from all charts of patients in the Cincinnati Eye Institute/University of Cincinnati and University of Minnesota population with a diagnosis of...

journal_title：Cornea

authors： Tsai JH,Derby E,Holland EJ,Khatana AK

更新日期：2006-06-01 00:00:00