Efficacy of plasma rich in growth factors for the treatment of dry eye.

Abstract:

PURPOSE:To evaluate the efficacy of plasma rich in growth factors (PRGF) for the treatment of moderate/severe dry eye. METHODS:PRGF treatment was administered to 16 patients who had moderate/severe dry eye diagnosed and who had not responded previously to other standard treatments. We quantified several growth factors present in the PRGF of each patient and obtained quantitative registers of the symptoms (modified score dry eye questionnaire), both before and after PRGF treatment. We also performed impression cytology to determine the degree of squamous metaplasia before and after PRGF treatment. RESULTS:PRGF treatment was associated with a statistically significant improvement in score dry eye questionnaire values (P < 0.001). Results from impression cytology corroborated this improvement, but the reduction in the degree of squamous metaplasia was not statistically significant. In 75% of patients treated with PRGF, no further treatments were required, whereas in the remaining 25% other ocular treatments could be reduced. CONCLUSIONS:PRGF led to symptom improvement in patients with moderate/severe dry eye. Surprisingly, the symptoms recorded in the dry eye questionnaire do not always agree with the degree of squamous metaplasia measured by impression cytology.

journal_name

Cornea

journal_title

Cornea

authors

López-Plandolit S,Morales MC,Freire V,Grau AE,Durán JA

doi

10.1097/ICO.0b013e31820d86d6

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1312-7

issue

12

eissn

0277-3740

issn

1536-4798

journal_volume

30

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Corneal Transplantation in New Zealand 2000 to 2009.

    abstract:PURPOSE:To quantify all minor/major adverse events in a large cohort of consecutive corneal transplants, particularly in respect to penetrating keratoplasty (PKP). METHODS:All corneal transplants in the Auckland region over a 10-year period (2000-2009) were identified through the New Zealand National Eye Bank. Relevan...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001481

    authors: Crawford AZ,Krishnan T,Ormonde SE,Patel DV,McGhee CN

    更新日期:2018-03-01 00:00:00

  • Trocar-Assisted, Sutureless, Scleral-Fixated Intraocular Lens Implantation Combined With Penetrating Keratoplasty.

    abstract:PURPOSE:To evaluate the results of trocar-assisted, sutureless, scleral-fixated (SSF) intraocular lens (IOL) implantation combined with penetrating keratoplasty (PKP). METHODS:This study comprised 4 eyes (4 patients) undergoing trocar-assisted SSF-IOL implantation during PKP. The combined technique was performed in 3 ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000944

    authors: Karadag R,Bayramlar H,Azari AA,Rapuano CJ

    更新日期:2016-09-01 00:00:00

  • Temperature variations in eyebank containers: comparative study of corneal transport containers and packing methods.

    abstract::Two containers ("Iowa" and "Virginia") commonly used for transporting donor corneas, and various packing methods were evaluated for constancy of temperature maintenance. The larger Iowa container was found to be superior for extended storage. Packing methods that allowed the vials (containing McCarey-Kaufman medium) t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: York KK,Ward DE,Smith RE

    更新日期:1985-01-01 00:00:00

  • Glucocorticoids suppress corneal lymphangiogenesis.

    abstract:PURPOSE:To determine whether glucocorticoids suppress corneal lymphatic vessel growth (lymphangiogenesis) or induce lymphatic vessel regression. METHODS:We measured human lymphatic endothelial cell proliferation and collagen-induced tubulogenesis in culture conditions with and without dexamethasone, a potent glucocort...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318213f39f

    authors: Steele MM,Kelley PM,Schieler AM,Tempero RM

    更新日期:2011-12-01 00:00:00

  • The usefulness of routine alcian blue staining of corneal specimens.

    abstract::To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue stainin...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Weiss JS,Orlando F,Albert DM

    更新日期:1988-01-01 00:00:00

  • Clinicopathologic correlation of textural interface opacities in descemet stripping automated endothelial keratoplasty: a case study.

    abstract:PURPOSE:The aim of this study was to describe the clinicopathologic correlation of textural interface opacities (TIOs) in a Descemet stripping automated endothelial keratoplasty (DSAEK) donor button after its removal. METHODS:A 75-year-old woman underwent combined phacoemulsification with intraocular lens placement an...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000057

    authors: Newman LR,Rosenwasser GO,Dubovy SR,Matthews JL

    更新日期:2014-03-01 00:00:00

  • Peripheral ulcerative keratitis after Salmonella gastroenteritis.

    abstract:PURPOSE:To describe a case of bilateral peripheral ulcerative keratitis after Salmonella gastroenteritis. METHODS:Case report with description of treatment and outcome. RESULTS:The peripheral ulcerative keratitis gradually resolved in both eyes after appropriate systemic antibiotic therapy and local ocular care. CON...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199811000-00017

    authors: Yang J,Baltatzis S,Foster CS

    更新日期:1998-11-01 00:00:00

  • The effect of successful rebubbling after descemet stripping automated endothelial keratoplasty on endothelial cell counts.

    abstract:PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181cb40f6

    authors: Mashor RS,Kaiserman I,Kumar N,Sansanayudh W,Rootman D

    更新日期:2010-08-01 00:00:00

  • Intraoperative mitomycin C and corneal endothelium after pterygium surgery.

    abstract:PURPOSE:To determine the effect of mitomycin C (MMC) on the corneal endothelium after primary pterygium surgery. METHODS:This prospective, interventional, nonrandomized, observer-masked study included 46 consecutive patients (51 eyes) with primary pterygium. The bare sclera technique with 1-minute application of 0.02%...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181a3c548

    authors: Pérez-Rico C,Benítez-Herreros J,Montes-Mollón MA,Germain F,Castro-Rebollo M,Gómez-SanGil Y,Paz-Moreno J,Teus MA

    更新日期:2009-12-01 00:00:00

  • Excision of granulation tissue and free conjunctival autograft in the management of necrotizing scleritis.

    abstract:PURPOSE:To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS:Interventional case report. RESULTS:A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retra...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181b532e5

    authors: Gregory ME,Weir CR,Ramaesh K

    更新日期:2010-05-01 00:00:00

  • Corneal endothelial cell damage after lens extraction using the fluid-based system compared to ultrasound phacoemulsification in human cadaver eyes.

    abstract:PURPOSE:To compare the endothelial cell damage after lens removal using a fluid-based system to conventional ultrasound. METHODS:Twenty human cadaver eyes were randomized to undergo phacoemulsification using either a fluid-based system or conventional ultrasound. After surgery, each corneoscleral button was removed, s...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000130184.56514.51

    authors: Sandoval HP,Al Sarraf O,Vroman DT,Solomon KD

    更新日期:2004-10-01 00:00:00

  • Determining Factors for Fast Corneal Sensitivity Recovery After Pterygium Excision.

    abstract:PURPOSE:To establish determining factors for fast corneal sensitivity (CS) recovery after pterygium excision. METHODS:Thirty-two eyes of 14 males and 18 females with primary nasal pterygium were recruited. Differences in CS (in the 4 quadrants and the center using a Cochet-Bonnet esthesiometer), pterygium corneal area...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000932

    authors: Julio G,Campos P,Pujol P,Munguia A,Mas-Aixala E

    更新日期:2016-12-01 00:00:00

  • Xylene keratopathy: a case report and review of the literature.

    abstract:PURPOSE:To report a case of direct contact xylene-related vacuolar keratopathy. METHODS:Interventional case report and review of the literature. RESULTS:Xylene keratopathy is a distinct clinical entity characterized by significantly decreased visual acuity, increased corneal thickness, and the presence of corneal epi...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200301000-00023

    authors: Trujillo F,Dang D,Starck T

    更新日期:2003-01-01 00:00:00

  • Donor eyes. A comparison of characteristics and outcomes for Eye Bank and local tissue.

    abstract::The Corneal Recipient Registry was begun in 1985 to collect information on all recipients of corneal grafts in the province of Ontario, Canada, and on the donors providing tissue. While most of the tissue is handled by the Eye Bank of Canada (Ontario Division), ophthalmologists in centers away from the Eye Bank often ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Chipman ML,Willett P,Basu PK,Wolf A

    更新日期:1989-01-01 00:00:00

  • Modified Ruiz procedure for reducing high astigmatism after penetrating keratoplasty.

    abstract:PURPOSE:To evaluate the refractive, keratometric, and visual outcomes of a modified Ruiz procedure in patients with high astigmatism after penetrating keratoplasty (PKP). METHODS:Retrospective cohort study with 26 eyes of 24 patients. A modified Ruiz incision pattern was used. Two paired arcuate incisions, centered on...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318153f241

    authors: Zuberbuhler B,Agrawal A,Gale R,Kipioti T,Gauba V,Noble B

    更新日期:2007-12-01 00:00:00

  • "Pleats fold" technique of amniotic membrane transplantation for management of corneal perforations.

    abstract:PURPOSE:The aim of this study was to examine the efficacy and surgical success rates of amniotic membrane (AM) transplantation performed for corneal perforation closure using a novel technique. METHODS:This study included 6 eyes from 6 patients with corneal perforation who had received AM transplantation between May 2...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000128

    authors: Namba H,Narumi M,Nishi K,Goto S,Hayashi S,Yamashita H

    更新日期:2014-06-01 00:00:00

  • Limbal stem cell-sparing lamellar keratoplasty for the management of advanced keratoglobus.

    abstract:PURPOSE:To describe the technique and outcomes of limbal stem cell-sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). METHODS:In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patient...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182a9b1ac

    authors: Karimian F,Baradaran-Rafii A,Faramarzi A,Akbari M

    更新日期:2014-01-01 00:00:00

  • Comparison of bifold forceps and cartridge injector suture pull-through insertion techniques for Descemet stripping automated endothelial keratoplasty.

    abstract:PURPOSE:To compare the outcome of bifold forceps and cartridge injector suture pull-through insertion techniques for Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:A retrospective review was conducted of the medical records of all patients treated with DSAEK at the University of Iowa Hospitals ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181eadb84

    authors: Wendel LJ,Goins KM,Sutphin JE,Wagoner MD

    更新日期:2011-03-01 00:00:00

  • Pregnancy-induced progression of keratoconus.

    abstract:PURPOSE:To report eyes with keratoconus that progressed during pregnancy. METHODS:Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was docu...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182068adc

    authors: Bilgihan K,Hondur A,Sul S,Ozturk S

    更新日期:2011-09-01 00:00:00

  • Histological analysis of a cornea following experimental femtosecond laser ablation.

    abstract::Corneal photorefractive surgery is currently performed by ablation of corneal stroma under the stromal flap. A stromal flap is created using a femtosecond (FS) laser or mechanical microkeratome, although the FS laser procedure is considered safer and more accurate. This review assesses and compares the use of FS laser...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0000000000000251

    authors: Sumioka T,Miyamoto T,Takatsuki R,Okada Y,Yamanaka O,Saika S

    更新日期:2014-11-01 00:00:00

  • Ceramide-induced apoptosis in rabbit corneal fibroblasts.

    abstract:PURPOSE:To evaluate the effect of various ceramides on the apoptosis of corneal fibroblasts and to determine the pathway on which they act. METHOD:Corneal fibroblasts isolated and cultured from New Zealand white rabbits were exposed to various concentrations of ceramide types II and VI and phytoceramide types II and V...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000134000.52886.c3

    authors: Kim TI,Pak JH,Tchah H,Lee SA,Kook MS

    更新日期:2005-01-01 00:00:00

  • Corneal complications of herpes zoster ophthalmicus. Prevention and treatment.

    abstract::Corneal complications of herpes zoster ophthalmicus include pseudodendritic keratitis, late mucous adherent keratopathy, varied forms of stromal keratitis, and exposure/neurotrophic keratopathy. Prophylactic therapy of acute herpes zoster ophthalmicus with oral acyclovir is of proven benefit in reducing the incidence ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Cobo LM

    更新日期:1988-01-01 00:00:00

  • A case of infectious crystalline keratopathy occurring long after penetrating keratoplasty.

    abstract:PURPOSE:To report a 64-year-old woman's case of infectious crystalline keratopathy (ICK) that occurred 9 years after the penetrating keratoplasty (PKP). METHODS:This study includes clinical history and histopathologic findings of the case. RESULTS:As historic background, the patient underwent PKP for lattice dystroph...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199801000-00018

    authors: Matsumoto A,Sano Y,Nishida K,Yokoi N,Hara J,Kinoshita S

    更新日期:1998-01-01 00:00:00

  • Corneoscleral epithelial cysts: evidence of developmental etiology.

    abstract:PURPOSE:To describe the clinical features, histopathology, surgical management and possible etiopathogenesis of corneoscleral epithelial cysts. METHODS:Three patients with corneoscleral epithelial cysts underwent surgical ablation of the cysts. Material obtained during surgery was subjected to histopathologic analysis...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199807000-00018

    authors: Rao SK,Fogla R,Biswas J,Padmanabhan P

    更新日期:1998-07-01 00:00:00

  • Three decades of corneal transplantation: indications and patient characteristics.

    abstract:PURPOSE:To review the indications and patient characteristics for penetrating keratoplasty (PKP). METHODS:Retrospective review of records at the Pathology Service, Department of Ophthalmology, University of Toronto from 1964 to 1997. RESULTS:The 6,222 records were reviewed. The leading indications for PKP were regraf...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200001000-00002

    authors: Maeno A,Naor J,Lee HM,Hunter WS,Rootman DS

    更新日期:2000-01-01 00:00:00

  • Endothelial rejection following penetrating keratoplasty using Healon or BSS.

    abstract::In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Musch DC,Meyer RF,Sugar A,Soong HK

    更新日期:1990-10-01 00:00:00

  • Advanced fusarium keratitis progressing to endophthalmitis.

    abstract:PURPOSE:To review the clinical course, treatment, and visual outcomes of keratitis with endophthalmitis caused by the filamentary fungus Fusarium. METHOD:One hundred fifty-nine cases of Fusarium keratitis at Bascom Palmer Eye Institute between January 1, 1987 and August 21, 2000 were reviewed. Ten patients with cultur...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200305000-00004

    authors: Dursun D,Fernandez V,Miller D,Alfonso EC

    更新日期:2003-05-01 00:00:00

  • Femtosecond laser-assisted inverted mushroom keratoplasty.

    abstract:PURPOSE:To evaluate best-corrected visual acuity (BCVA), refractive outcome, corneal topography, optical coherence tomography, and endothelial cell density 12 months after femtosecond laser-assisted inverted mushroom keratoplasty. METHODS:We performed a prospective study of a surgical case series of 5 patients undergo...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/QAI.0b013e31815bad0c

    authors: Cheng YY,Tahzib NG,van Rij G,van Cleynenbreugel H,Pels E,Hendrikse F,Nuijts R

    更新日期:2008-07-01 00:00:00

  • Nanoscale topography of the corneal epithelial basement membrane and Descemet's membrane of the human.

    abstract:PURPOSE:Quantitatively define and compare the nanoscale topography of the corneal epithelial basement membrane (anterior basement membrane) and Descemet's membrane (posterior basement membrane) of the human. METHODS:Human corneas not suitable for transplantation were obtained from the Wisconsin Eye Bank. The corneas w...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200001000-00012

    authors: Abrams GA,Schaus SS,Goodman SL,Nealey PF,Murphy CJ

    更新日期:2000-01-01 00:00:00

  • A Novel Mobile Application for Preoperative and Intraoperative Assessments of Intrastromal Corneal Ring Segments Implantation for Keratoconus.

    abstract:PURPOSE:To develop a mobile app that allows photographs to be captured and edited under the overlay of images and projection of a protractor with 360 degrees axis markings, which enables the surgeon to accurately visualize the programmed and marked alignment where the intrastromal corneal ring segments (ICRS) will be i...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002385

    authors: Fernandes Dias FA,Fernandes Dias VJ,Carneiro CLB,Bernardes BG,Dutra BAL,Crispim Ribeiro J

    更新日期:2020-09-01 00:00:00