Evaluation of Anterior and Posterior Corneal Irregularity After Descemet Membrane Endothelial Keratoplasty.

abstract：PURPOSE:To evaluate the safety, validity, and comfort of 0.35% fluorexon disodium and 0.4% benoxinate (Flura-Safe) compared with the gold standard of 0.25% sodium fluorescein and 0.4% benoxinate for Goldmann applanation tonometry (GAT). METHODS:This was a double-masked, randomized, crossover clinical trial. Subjects r...

journal_title：Cornea

authors： Ng LT,Tong JW,De Land PN

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:The 27-kDa heat shock protein (HSP27) has been implicated in wound healing in multiple tissues. We investigated the expression and localization of phosphorylated HSP27 during epithelial wound healing in the murine cornea. METHODS:Corneas of 8- to 10-week-old C57BL6 mice were wounded by epithelial debridement (...

journal_title：Cornea

authors： Jain S,De la Cruz J,Kang E,Kojima T,Chang JH,Kim JY

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate both the direct and indirect annual cost of managing dry eye disease (DED) in the United States from a societal and a payer's perspective. METHODS:A decision analytic model was developed to estimate the annual cost for managing a cohort of patients with dry eye with differ...

journal_title：Cornea

authors： Yu J,Asche CV,Fairchild CJ

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Corneal lesions such as ulcers and erosions are major complications observed in patients with severe ocular allergic diseases. We aimed to look into the relationship between specific clinical conjunctival findings and the severity of corneal complications. METHODS:Thirty eyes of 6 patients with vernal kerato...

journal_title：Cornea

authors： Tanaka M,Dogru M,Takano Y,Miyake-Kashima M,Asano-Kato N,Fukagawa K,Tsubota K,Fujishima H

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

journal_title：Cornea

authors： Wang Z,Zhao H,Ma JX,Xu X

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:Our study fills the spatiotemporal gaps in dry eye disease (DED) epidemiology by using Google Trends as a novel epidemiological tool for geographically mapping DED in relation to environmental risk factors. METHODS:We used Google Trends to extract DED-related queries estimating users' intent from 2004 to 2019 ...

journal_title：Cornea

authors： Azzam DB,Nag N,Tran J,Chen L,Visnagra K,Marshall K,Wade M

更新日期：2020-11-06 00:00:00

abstract：PURPOSE:To compare the relative diagnostic value of confocal microscopy and superficial corneal cultures in the diagnosis of Acanthamoeba keratitis by using clinical and microbiologic definitions of disease. METHODS:Results of confocal microscopy, superficial corneal smear, and superficial corneal culture were analyze...

journal_title：Cornea

authors： Tu EY,Joslin CE,Sugar J,Booton GC,Shoff ME,Fuerst PA

更新日期：2008-08-01 00:00:00

abstract：:Corneal epithelial permeability studies using fluorophotometers were performed on 90 eyes of 51 normal subjects. After recording the autofluorescence of the cornea (AFC) and of the lens (AFL), we applied 20 microliters of 2% sodium fluorescein to the conjunctival sac. The corneal fluorescence 45 min later (F45), which...

journal_title：Cornea

authors： Chang SW,Hu FR

更新日期：1993-11-01 00:00:00

abstract：PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...

journal_title：Cornea

authors： May WN,Castro-Combs J,Kashiwabuchi RT,Tattiyakul W,Qureshi-Said S,Hirai F,Behrens A

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. METHODS:Retrospective, descriptive, nonrandomized case series. RESULTS:Thirty-five eyes of 18 patients (14 cases from 6 families and 4 isolated cases) with diffuse posterior polymorphous corneal dys...

journal_title：Cornea

authors： Raber IM,Fintelmann R,Chhabra S,Ribeiro MP,Eagle RC Jr,Orlin SE

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To assess the clinical outcomes after sequential surgical implantation of intracorneal ring segments and transepithelial corneal collagen cross-linking (TE-CXL) in keratoconic eyes. METHODS:In this consecutive randomized study, 40 eyes of 29 patients with progressive mild to moderate keratoconus were included ...

journal_title：Cornea

authors： Elsaftawy HS,Ahmed MH,Saif MY,Mousa R

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:This study was designed to assess the success of surgical monovision in presbyopic patients. METHODS:A university refractive surgery center retrospective chart review of 82 patients who elected to undergo surgical monovision with laser in situ keratomileusis (LASIK) between January 2000 and January 2003 was co...

journal_title：Cornea

authors： Reilly CD,Lee WB,Alvarenga L,Caspar J,Garcia-Ferrer F,Mannis MJ

更新日期：2006-02-01 00:00:00

abstract：:The mechanism of ocular surface allergy in the forms of atopic conjunctivitis and vernal keratoconjunctivitis has been highlighted by specific functions of chemokines. In the context of late-phase allergic responses, these molecules have key roles in recruitment and activation of leukocytes. Their interaction with lig...

journal_title：Cornea

authors： Miyazaki D,Nakamura T,Komatsu N,Nawata N,Ikeda Y,Inoue Y,Higashi H,Ono SJ

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients with type 2 diabetes mellitus. METHODS:Patients with type 2 diabetes without diabetic retinopathy (DR) (n = 54), with nonproliferative DR (n = 45), with proliferative DR (PDR) (n = 25), and controls (n = 4...

journal_title：Cornea

authors： Baek J,Doh SH,Chung SK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To compare the efficacy of conjunctival resection versus conjunctival resection with amniotic membrane graft (AMG) in patients with superior limbic keratoconjunctivitis not responsive to medical therapies. METHODS:In a retrospective and comparative study, 16 eyes of 9 patients with long-lasting superior limbic...

journal_title：Cornea

authors： Gris O,Plazas A,Lerma E,Güell JL,Pelegrín L,Elíes D

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...

journal_title：Cornea

authors： Theoulakis P,Goldblum D,Zimmerli S,Muehlethaler K,Frueh BE

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:To evaluate the refractive, keratometric, and visual outcomes of a modified Ruiz procedure in patients with high astigmatism after penetrating keratoplasty (PKP). METHODS:Retrospective cohort study with 26 eyes of 24 patients. A modified Ruiz incision pattern was used. Two paired arcuate incisions, centered on...

journal_title：Cornea

authors： Zuberbuhler B,Agrawal A,Gale R,Kipioti T,Gauba V,Noble B

更新日期：2007-12-01 00:00:00

abstract：:Corneal intraepithelial neoplasia (CIN) is the term applied by some authors to the spectrum of disease ranging from mild dysplasia to carcinoma in situ. Such lesions usually are associated with dysplastic or neoplastic processes at the limbus or adjacent conjunctiva; isolated corneal dysplasia is rare. Clinically, CIN...

journal_title：Cornea

authors： Brown HH,Glasgow BJ,Holland GN,Foos RY

更新日期：1989-09-01 00:00:00

abstract：:The authors describe the clinical, molecular genetic, and pathologic findings of a patient with corneal decompensation associated with the mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. Ultrastructurally abnormal mitochondria were observed and possibly implicate this organelle in the pathogenesis of corne...

journal_title：Cornea

authors： Chang TS,Johns DR,Stark WJ,Drachman DB,Green WR

更新日期：1994-05-01 00:00:00

abstract：PURPOSE:To document the relationship of iris cavernous hemangiomas with multiorgan hemangiomas in a child. METHODS:A 7-year-old girl with kidney hemangiomas, brain hemangiomas, and skin hemangiomas developed blurred vision and darkening of the right iris. She had undergone 6 previous brain surgeries and multiple revis...

journal_title：Cornea

authors： Thangappan A,Shields CL,Dinowitz M,Shields JA

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of Descemet membrane endothelial keratoplasty (DMEK) performed after previous penetrating keratoplasty (PK) failure and to describe primary outcomes. METHODS:Twenty-eight eyes of 28 patients who underwent DMEK after primary PK failure between January 2013 and November 2017 were i...

journal_title：Cornea

authors： Pierné K,Panthier C,Courtin R,Mazharian A,Souedan V,Gatinel D,Saad A

更新日期：2019-03-01 00:00:00

abstract：:Posterior amorphous corneal dystrophy (PACD) is a rare autosomal-dominant disease, generally classified with the pre-Descemet's dystrophies. It is characterized by deep stromal corneal opacification, flat corneas with low keratometry values, and central thinning. To our knowledge, only one previous ultrastructural stu...

journal_title：Cornea

authors： Roth SI,Mittelman D,Stock EL

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:To determine if Cornisol is as effective as Optisol-GS as an intermediate-term corneal storage medium. METHODS:A prospective, in vitro, randomized, partially masked study using paired donor corneas. Optical grade tissues not suitable for surgery were used. After performing baseline slit lamp evaluation, one ti...

journal_title：Cornea

authors： Basak S,Prajna NV

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To evaluate the changes and trends in the number and characteristics of contact lens-related ulcers (CLRUs) and to compare the results with those of previously published series at our institution. METHODS:Medical records of all patients diagnosed with presumed bacterial corneal ulcers seen at the Cornea Servic...

journal_title：Cornea

authors： Yildiz EH,Airiani S,Hammersmith KM,Rapuano CJ,Laibson PR,Virdi AS,Hongyok T,Cohen EJ

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:To report a newly developed noninvasive method to measure the radius of tear meniscus curvature (reflective meniscometry) and its application to normal eyes, dry eyes, and other ocular surface conditions. METHODS:Two types of meniscometer--photographic and video--were devised. Both use tear meniscus as a conca...

journal_title：Cornea

authors： Yokoi N,Bron AJ,Tiffany JM,Kinoshita S

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To investigate the feasibility of corneal reconstruction utilizing cultured human corneal endothelial cells (HCECs). METHODS:We cultivated HCECs using culture dishes pre-coated with bovine corneal endothelial extracellular matrix. The effect of donor age on HCECs was investigated. We reconstructed corneas usin...

journal_title：Cornea

authors： Amano S

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To establish determining factors for fast corneal sensitivity (CS) recovery after pterygium excision. METHODS:Thirty-two eyes of 14 males and 18 females with primary nasal pterygium were recruited. Differences in CS (in the 4 quadrants and the center using a Cochet-Bonnet esthesiometer), pterygium corneal area...

journal_title：Cornea

authors： Julio G,Campos P,Pujol P,Munguia A,Mas-Aixala E

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:The VCH-1 was calibrated against a standard subjective Abbé refractometer using 7 randomly selected turbid semiliquid media. VCH...

journal_title：Cornea

authors： Patel S,Alió JL,Amparo F,Rodriguez-Prats JL

更新日期：2011-12-01 00:00:00

abstract：:To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue stainin...

journal_title：Cornea

authors： Weiss JS,Orlando F,Albert DM

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To compare the endothelial cell damage after lens removal using a fluid-based system to conventional ultrasound. METHODS:Twenty human cadaver eyes were randomized to undergo phacoemulsification using either a fluid-based system or conventional ultrasound. After surgery, each corneoscleral button was removed, s...

journal_title：Cornea

authors： Sandoval HP,Al Sarraf O,Vroman DT,Solomon KD

更新日期：2004-10-01 00:00:00