Abstract:
PURPOSE:To establish determining factors for fast corneal sensitivity (CS) recovery after pterygium excision. METHODS:Thirty-two eyes of 14 males and 18 females with primary nasal pterygium were recruited. Differences in CS (in the 4 quadrants and the center using a Cochet-Bonnet esthesiometer), pterygium corneal area (PCA), tear osmolarity, tear break-up time, Schirmer test, and ocular symptoms were analyzed before and 1 month after lesion excision. The relationship between CS recovery (difference between the 2 time points; CS1 - CS0) and the other features was assessed. RESULTS:All the studied locations exhibited normal (6 cm) or near-normal mean CS at the 2 time points, except a tendency for moderate hypoesthesia in nasal CS0 (median 4.5; range: 1.5-6.0 cm). Point by point comparison revealed significant postoperative improvements in nasal location (P = 0.008; Wilcoxon signed-rank test) with normal values in 17 eyes (53%) and a median CS1 = 5.0 cm (2.5-5.5 cm) in 15 eyes with no complete recovery. No significant correlation was found between CS0 and the studied variables, and CS1 was only significantly correlated with PCA (rho: -0.441; P < 0.05). CS recovery also showed significant correlation with PCA (rho = -0.516; P < 0.01). CONCLUSIONS:CS recovery after pterygium excision showed important variability, and the only studied factor that seems to be determinant could be PCA. It would be advisable to operate when the lesion is relatively small, with lower surgical injury and faster and complete recovery, thus protecting ocular surface homeostasis.
journal_name
Corneajournal_title
Corneaauthors
Julio G,Campos P,Pujol P,Munguia A,Mas-Aixala Edoi
10.1097/ICO.0000000000000932subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1594-1599issue
12eissn
0277-3740issn
1536-4798journal_volume
35pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To report 5-year outcomes for graft survival and endothelial cell survival after Descemet stripping endothelial keratoplasty (DSEK) including regression modeling for cell survival over time. METHODS:This is a single-institution, retrospective, consecutive interventional series of 210 primary DSEK grafts operat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001177
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To compare the efficacy of conjunctival resection versus conjunctival resection with amniotic membrane graft (AMG) in patients with superior limbic keratoconjunctivitis not responsive to medical therapies. METHODS:In a retrospective and comparative study, 16 eyes of 9 patients with long-lasting superior limbic...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181d1d1cc
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To describe an impression cytology (IC) technique using a purpose-built, sterile, EYEPRIM IC device that can be coupled with a TRIzol reagent-based RNA extraction protocol to yield sufficient RNA for gene expression analysis. METHODS:IC samples using the EYEPRIM device were collected from the bulbar conjunctiv...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/ICO.0000000000001792
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report a recent significant increase of the number of patients diagnosed with Acanthamoeba keratitis (AK) at Wills Eye Hospital between 2004 and 2005. To determine the risk factors, clinical characteristics, treatments, and outcomes of patients with AK. METHODS:Retrospective consecutive case series of 20 ey...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31805b7e63
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:The aim of this study was to estimate both the direct and indirect annual cost of managing dry eye disease (DED) in the United States from a societal and a payer's perspective. METHODS:A decision analytic model was developed to estimate the annual cost for managing a cohort of patients with dry eye with differ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181f7f363
更新日期:2011-04-01 00:00:00
abstract::In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...
journal_title:Cornea
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:Compare corneal endothelial image analysis by Konan SP8000 and Bio-Optics Bambi image-analysis systems. METHODS:Corneal endothelial images from 98 individuals (191 eyes), ranging in age from 4 to 87 years, with a normal slit-lamp examination and no history of ocular trauma, intraocular surgery, or intraocular ...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To compare the therapeutic effects of topical tumor necrosis factor (TNF)-α-stimulated gene/protein-6 (TSG-6) with those of cyclosporine and prednisolone eye drops in NOD.B10.H2 mice, a model for inflammation-mediated dry eye. METHODS:The 12-week-old NOD.B10.H2 mice were topically administered recombinant TSG-...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000756
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31818c2c36
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:Young children are prone to develop amblyopia after penetrating injury. We sought to evaluate the management of penetrating corneal injury without intraocular foreign body (IOFB) in children journal_title:Cornea pub_type: 杂志文章 doi:10.1097/ICO.0b013e3180301534 更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To report a case of conjunctival proliferation in a 2.5-year-old boy after initial evidence of a mild chemical injury after ocular exposure to pepper spray (oleoresin capsicum). METHODS:Case report with ophthalmologic and histologic findings. RESULTS:A child presented with mild conjunctival injection and chem...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318206cad9
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To describe the incidence and prevalence of glaucoma in a patient population with severe ocular surface disease (OSD). METHODS:A retrospective case series was compiled from all charts of patients in the Cincinnati Eye Institute/University of Cincinnati and University of Minnesota population with a diagnosis of...
journal_title:Cornea
pub_type: 杂志文章,多中心研究
doi:10.1097/01.ico.0000220776.93852.d9
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS:Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DM...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001554
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To evaluate the long-term changes in anterior and posterior corneal irregular astigmatism and curvatures after small incision lenticule extraction (SMILE). METHODS:Fifty eyes of 28 patients underwent SMILE for myopic astigmatism. All procedures were performed using the VisuMax® femtosecond laser. A Scheimpflug...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001532
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To compare the effects of levobunolol hydrochloride and timolol maleate on tear volume, precorneal tear film stability, and corneal epithelial barrier function in normal human eyes. SUBJECTS AND METHODS:The study population consisted of 14 healthy volunteers. To obtain pretreatment baseline values, we determin...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200311000-00001
更新日期:2003-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to describe the clinicopathologic correlation of textural interface opacities (TIOs) in a Descemet stripping automated endothelial keratoplasty (DSAEK) donor button after its removal. METHODS:A 75-year-old woman underwent combined phacoemulsification with intraocular lens placement an...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000057
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200005000-00021
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:To compare dry eye disease parameters between small incision lenticule extraction (SMILE) and laser subepithelial keratomileusis (LASEK). METHODS:This prospective, nonrandomized study included 39 eyes of 39 patients who underwent SMILE (n = 19) and LASEK (n = 20). Dry eye disease parameters included Ocular Sur...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002240
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:To report the use of excimer laser phototherapeutic keratectomy (PTK) in the treatment of corneal subepithelial nodular scarring in a child with Rothmund-Thomson syndrome (RTS), a form of ectodermal dysplasia. METHODS:A case report and review of the literature. RESULTS:Excimer laser PTK successfully treated t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200001000-00022
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:To report an unusual case of epithelial ingrowth after phacoemulsification with posterior chamber intraocular lens implantation in a patient with recurrent pterygium, along with confocal microscopy findings of epithelial ingrowth. METHODS:This is a case report and review of the literature. RESULTS:A healthy 6...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002158
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:Microbiological contamination is a common cause for elimination of organ-cultured donor corneas. The aims of the present study were to analyze contamination rates and identify risk factors for contamination. METHODS:Retrospectively, the contamination rates of 4546 organ-cultured corneas and the causative speci...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31825d586b
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:To describe the association of water exposure with contact lens (CL)-related disease and explore the guidelines regarding water exposure to CL wearers, provided by CL manufacturing industry, global public health, and CL-related professional associations. METHODS:A review of the literature was conducted by sear...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000001898
更新日期:2019-06-01 00:00:00
abstract::An understanding of corneal optics is important to optimize the visual outcome after eye surgery. Recent advances in the surgical techniques of lamellar keratoplasty have changed the strategies used for corneal transplantation. Lamellar keratoplasty has the advantage of having a lower rate of graft rejection, superior...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000000589
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS:Interventional case report. RESULTS:A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retra...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181b532e5
更新日期:2010-05-01 00:00:00
abstract::A randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted in five centers to assess safety, ocular tolerance, and efficacy of an ophthalmic solution of epidermal growth factor (EGF) for the treatment of traumatic corneal epithelial defects. One hundred four patients completed the study: ...
journal_title:Cornea
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/00003226-199207000-00007
更新日期:1992-07-01 00:00:00
abstract::The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels were present in the periphery of debrided corneas at 1 h (90.12 +/- ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199109000-00010
更新日期:1991-09-01 00:00:00
abstract:PURPOSE:To evaluate changes in the anterior chamber of eyes that have undergone Descemet membrane endothelial keratoplasty (DMEK) and to identify factors that affect these changes. METHODS:This retrospective study included 25 pseudophakic eyes of 25 patients who underwent DMEK. We determined the preoperative and posto...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002535
更新日期:2020-09-29 00:00:00
abstract::Corneal photorefractive surgery is currently performed by ablation of corneal stroma under the stromal flap. A stromal flap is created using a femtosecond (FS) laser or mechanical microkeratome, although the FS laser procedure is considered safer and more accurate. This review assesses and compares the use of FS laser...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000000251
更新日期:2014-11-01 00:00:00
abstract::Epithelium plays a very important structural and functional role in the cornea and conjunctiva. Evaluation of the epithelium is the first step in diagnosing many pathologic states. We have developed a new technique for the in vivo staining of nuclei of corneal and conjunctival epithelium in rabbits and guinea pigs. Se...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::There recently have been several reports of microsporidial keratoconjunctivitis caused by the organism Encephalitozoon hellem. However, treatment of this infection has been largely ineffective. We report a case of a 35-year-old Hispanic woman with AIDS and E. hellem keratoconjunctivitis confirmed with light, electron,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199305000-00013
更新日期:1993-05-01 00:00:00