Abstract:
PURPOSE:To address the effect of topical instillation of oxybuprocaine on the relative distribution of corneal thickness (CT) in young healthy subjects. METHODS:Prospective study involving 30 eyes of 30 emmetropic subjects (24 ± 3 years). Corneal thickness measurements were carried out before and 3 minutes after the instillation of oxybuprocaine 4% using slit-scanning corneal topography (Orbscan topography system II). No acoustic correction factor was applied. The mean of 5 consecutive Orbscan measurements was obtained at the center and 3 mm from the visual axis in the temporal, superior, nasal, and inferior hemimeridians. RESULTS:No significant mean differences were found at any corneal location after anesthesia (P > 0.05). The difference between the baseline values obtained of the central, superior, inferior, nasal, and temporal cornea and those obtained after anesthesia ranged from -15 to 16 μm, from -19 to 32 μm, from -14 to 24 μm, from -20 to 33 μm, and from -31 to 18 μm, respectively. The maximum paracentral CT was never found at the temporal location before anesthesia, whereas it was never found at the inferior location after anesthesia. The minimum paracentral CT was never found in the superior location after anesthesia. CONCLUSIONS:Topical anesthetic eye drops induce CT increases and decreases at each corneal location; however, the differences are not significant. Nevertheless, a change in the location of the minimum and maximum paracentral thickness occurs in some individuals after corneal anesthesia.
journal_name
Corneajournal_title
Corneaauthors
Sanchis-Gimeno JA,Palanca-Sanfrancisco JM,García-Lázaro S,Madrid-Costa D,Cerviño Adoi
10.1097/ICO.0b013e318275e7a6subject
Has Abstractpub_date
2013-05-01 00:00:00pages
e102-5issue
5eissn
0277-3740issn
1536-4798journal_volume
32pub_type
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