Abstract:
:Two patients developed graft versus host disease (GvHD) following allogeneic bone marrow transplantation for leukemia. One patient developed acute GvHD 12 days after transplantation, and the second developed chronic GvHD 100 days after transplantation. Tear analysis and conjunctival impression cytology were performed. The results were compared to a normal control and to another patient who was 18 months status post bone marrow transplantation with successfully treated GvHD. Tear sampling on the patient with chronic GvHD revealed greatly elevated IgG levels with an inverse IgG to IgA ratio, as compared with normals. In addition, two of three leukemia patients demonstrated decreased mucin levels in tears. Conjunctival impression cytology from the patient with chronic GvHD revealed an abundance of plasma cells.
journal_name
Corneajournal_title
Corneaauthors
Heitman KF,Lam KW,Maskin SL,Yee RW,Lawton AWsubject
Has Abstractpub_date
1988-01-01 00:00:00pages
57-62issue
1eissn
0277-3740issn
1536-4798journal_volume
7pub_type
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