Topical cyclosporine in the management of shield ulcers.

abstract：PURPOSE:The aim of this study is to determine the effect of variation of the exposure time of near-infrared irradiation on corneal stiffening after a bacteriochlorophyll derivative (WST11) with dextran (WST-D) application. METHODS:One hundred four paired eyes of 3-month-old New Zealand White rabbits were included in t...

journal_title：Cornea

authors： Brekelmans J,Goz A,Dickman MM,Brandis A,Sui X,Wagner HD,Nuijts RMMA,Scherz A,Marcovich AL

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To identify potential donor, recipient, surgical, and postoperative factors that may influence survival and visual outcome of penetrating keratoplasty (PKP). METHODS:As part of a prospective longitudinal study, the electronic records of the New Zealand National Eye Bank were analyzed for the 10-year period fro...

journal_title：Cornea

authors： Patel HY,Ormonde S,Brookes NH,Moffatt SL,Sherwin T,Pendergrast DG,McGhee CN

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To evaluate the prevalence of positive microbiology results (culture and/or Gram stain) in donor cornea tissue with newer transplant methods and to assess if the results subsequently correlate with higher incidence of clinical infection. METHODS:A retrospective review of the microbiology records of 569 consecu...

journal_title：Cornea

authors： Garg S,Said B,Farid M,Steinert RF

更新日期：2013-02-01 00:00:00

abstract：:The many published studies on sterile procedures used by eye banks have included none until now on ways to optimize sterile handling of corneas procured in the morgues of forensic pathologists. The present study sought to discover if fewer positive cultures would be reported at the time of surgery from corneas which h...

journal_title：Cornea

authors： Farge EJ,Fort RA

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To retrospectively evaluate the results of myopic photorefractive keratectomy (PRK) for different levels of intended correction, including analysis of loss of best spectacle-corrected visual acuity. METHODS:Four hundred seventy-five consecutive eyes with 1 year of follow-up that had PRK for the correction of 1...

journal_title：Cornea

authors： Kapadia MS,Wilson SE

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:To evaluate changes in the anterior chamber of eyes that have undergone Descemet membrane endothelial keratoplasty (DMEK) and to identify factors that affect these changes. METHODS:This retrospective study included 25 pseudophakic eyes of 25 patients who underwent DMEK. We determined the preoperative and posto...

journal_title：Cornea

authors： Onouchi H,Hayashi T,Shimizu T,Matsuzawa A,Suzuki Y,Kato N

更新日期：2020-09-29 00:00:00

abstract：PURPOSE:To assess the efficacy and safety of combined intracameral sulfur hexafluoride and full-thickness corneal sutures in the treatment of acute corneal hydrops (CH). METHODS:This is an uncontrolled series of cases with keratoconus (KC), keratoglobus (KG), and pellucid marginal degeneration that presented with CH o...

journal_title：Cornea

authors： Mohebbi M,Pilafkan H,Nabavi A,Mirghorbani M,Naderan M

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To establish a time-proven "gold standard" in modified osteoodontokeratoprosthesis (OOKP) surgery. METHODS:The OOKP is the procedure of choice for restoring sight in patients with corneal blindness caused by end-stage ocular surface disease not amenable to penetrating keratoplasty. Members of the OOKP Study Gr...

journal_title：Cornea

authors： Hille K,Grabner G,Liu C,Colliardo P,Falcinelli G,Taloni M,Falcinelli G

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To analyze characteristics and indications for corneal transplantation in patients undergoing penetrating, lamellar, and endothelial keratoplasty in Auckland, New Zealand (NZ). METHODS:Corneal transplantation data from the NZ National Eye Bank and hospital records of corneal transplant recipients in the Auckla...

journal_title：Cornea

authors： Crawford AZ,McKelvie J,Craig JP,McGhee CN,Patel DV

更新日期：2017-05-01 00:00:00

abstract：:Posterior polymorphous corneal dystrophy (PPD) is a rare bilateral, autosomal-dominant disease. The presence of the epitheliumlike endothelium and the thickening of Descemet's membrane by the posterior collagenous layer (PCL) has been reported in the majority of published cases. Reepithelialization of the posterior co...

journal_title：Cornea

authors： Sekundo W,Lee WR,Aitken DA,Kirkness CM

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:To report a 64-year-old woman's case of infectious crystalline keratopathy (ICK) that occurred 9 years after the penetrating keratoplasty (PKP). METHODS:This study includes clinical history and histopathologic findings of the case. RESULTS:As historic background, the patient underwent PKP for lattice dystroph...

journal_title：Cornea

authors： Matsumoto A,Sano Y,Nishida K,Yokoi N,Hara J,Kinoshita S

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:To report eyes with keratoconus that progressed during pregnancy. METHODS:Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was docu...

journal_title：Cornea

authors： Bilgihan K,Hondur A,Sul S,Ozturk S

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To evaluate and compare corneal thickness in normal and dry eyes. METHODS:The Orbscan corneal topography system was used to measure the corneal thickness at nine locations in the central and peripheral (superior, superonasal, nasal, inferonasal, inferior, inferotemporal, temporal, superotemporal) cornea in 38 ...

journal_title：Cornea

authors： Liu Z,Pflugfelder SC

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND). METHODS:A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PT...

journal_title：Cornea

authors： Meltendorf C,Bühren J,Bug R,Ohrloff C,Kohnen T

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:To evaluate and compare corneal higher-order aberrations (HOAs) after Descemet stripping automated endothelial keratoplasty (DSAEK), femtosecond laser-assisted penetrating keratoplasty (FLAK), and conventional penetrating keratoplasty (PKP). METHODS:A retrospective comparison of consecutive surgical series of ...

journal_title：Cornea

authors： Chamberlain W,Omid N,Lin A,Farid M,Gaster RN,Steinert RF

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To evaluate the results of trocar-assisted, sutureless, scleral-fixated (SSF) intraocular lens (IOL) implantation combined with penetrating keratoplasty (PKP). METHODS:This study comprised 4 eyes (4 patients) undergoing trocar-assisted SSF-IOL implantation during PKP. The combined technique was performed in 3 ...

journal_title：Cornea

authors： Karadag R,Bayramlar H,Azari AA,Rapuano CJ

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

journal_title：Cornea

authors： Wang Z,Zhao H,Ma JX,Xu X

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:The goal of this study was to prospectively assess the deep lamellar endothelial keratoplasty (DLEK) wound anatomy and its evolution during the 12 months after surgery, using optical coherence tomography (OCT). METHODS:The eyes of 8 patients (1 eye per patient) who consecutively underwent DLEK for Fuchs dystro...

journal_title：Cornea

authors： Ferré LA,Nada O,Sherknies D,Boisjoly H,Brunette I

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...

journal_title：Cornea

authors： Bratton EM,Knutsen-Larson S,Durairaj VD,Gregory DG,Mellette JR

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate matrix metalloproteinases (MMP)-2, MMP-9, and tissue inhibitor of metalloproteinase (TIMP)-1 expression in a case of conjunctival intraepithelial squamous cell carcinoma (SCC) treated with topical 5-fluorouracil (5-FU) chemotherapy. METHODS:Clinicopathologic case report. RESULTS:A 71-year-old male...

journal_title：Cornea

authors： Iovieno A,Lambiase A,Moretti C,Perrella E,Bonini S

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:To evaluate clinical and ultrasonographic findings associated with advanced microbial keratitis with concurrent endophthalmitis. METHODS:We performed a retrospective analytical study of patients with severe microbial keratitis who underwent ocular ultrasonography for possible endophthalmitis at our institution...

journal_title：Cornea

authors： Christopher KL,Hood CT,Mian SI,Ayres B

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To measure subbasal nerve density and orientation in normal human corneas across a broad age range. METHODS:Sixty-five normal corneas of 65 subjects were examined by using tandem scanning confocal microscopy. Ages of subjects ranged from 15 to 79 years (mean 46 +/- 19 years), with 5 subjects from each hemideca...

journal_title：Cornea

authors： Erie JC,McLaren JW,Hodge DO,Bourne WM

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:To provide insight into the mechanism by which epidermal growth factor (EGF) stimulates corneal epithelial migration, we investigated the possible interaction between EGF and cyclic AMP (cAMP) signaling pathways during epithelial migration with an organ culture system for the rabbit cornea. METHODS:Rabbit corn...

journal_title：Cornea

authors： Nakamura M,Nishida T

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the outcome of penetrating keratoplasties, at the University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany, using organ-cultured donor corneas and to identify preoperative risk factors, which may influence the event of graft failure. METHODS:In this study, 3...

journal_title：Cornea

authors： Yu AL,Kaiser M,Schaumberger M,Messmer E,Kook D,Welge-Lussen U

更新日期：2014-11-01 00:00:00

abstract：:Posterior amorphous corneal dystrophy (PACD) is a rare autosomal-dominant disease, generally classified with the pre-Descemet's dystrophies. It is characterized by deep stromal corneal opacification, flat corneas with low keratometry values, and central thinning. To our knowledge, only one previous ultrastructural stu...

journal_title：Cornea

authors： Roth SI,Mittelman D,Stock EL

更新日期：1992-03-01 00:00:00

abstract：:Twelve FITC-conjugated lectins were used to establish a reaction pattern with cellular and noncellular components in fresh-frozen and formalin-fixed paraffin sections of 11 normal human corneas. In frozen sections the epithelium demonstrated the most active lectin staining; keratocytes and endothelium stained to a les...

journal_title：Cornea

authors： Brandon DM,Nayak SK,Binder PS

更新日期：1988-01-01 00:00:00

abstract：:Previous studies suggest the existence of two separate and distinct mechanisms of endothelial wound healing (i.e., cell migration and cell spreading), which may be controlled by unique, injury-dependent, wound-related factors. The purpose of our study was to evaluate potential biologic mediators regulating healing of ...

journal_title：Cornea

authors： Petroll WM,Jester JV,Barry-Lane PA,Cavanagh HD

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:To evaluate changes in the donor corneal endothelium in the intact globe and in the in vivo rabbit cornea to characterize more fully the formation of "dark events" without relief images in the endothelial mosaic. METHODS:Six ex vivo human donor corneas in the intact globe and an in vivo rabbit model were used ...

journal_title：Cornea

authors： Nartey IN,Cavanagh HD,Jester JV,Andrews P,Petroll WM

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of topical bevacizumab on ocular surface neovascularization among patients with Stevens-Johnson syndrome. METHODS:This was a retrospective, interventional case report. Three eyes of 2 patients were examined. Bevacizumab (25 mg/mL) eyedrops were applied 4 times daily for a pe...

journal_title：Cornea

authors： Uy HS,Chan PS,Ang RE

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS:Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DM...

journal_title：Cornea

authors： Lazaridis A,Fydanaki O,Giallouros E,Georgalas I,Kymionis G,Sekundo W,Droutsas K

更新日期：2018-07-01 00:00:00