Therapeutic effect of topical 5-fluorouracil in conjunctival squamous carcinoma is associated with changes in matrix metalloproteinases and tissue inhibitor of metalloproteinases expression.

abstract：:Eleven patients with severe corneal disease have been operated with a collar-button-shaped keratoprosthesis and have been followed for 9-36 months. Two of the devices have been removed, but the remainder are securely in place. Six of the patients have benefitted substantially in terms of improved vision. The complicat...

journal_title：Cornea

authors： Dohlman CH,Doane MG

更新日期：1994-05-01 00:00:00

abstract：PURPOSE:To determine the prevalence of herpes simplex virus type 1 (HSV-1) DNA in failed Descemet membrane stripping automated endothelial keratoplasty (DSAEK) grafts. METHODS:A retrospective interventional case series of patients with DSAEK graft failure treated at the New York Eye and Ear Infirmary between January 2...

journal_title：Cornea

authors： Yin D,Huang A,Warrow D,Ritterband DC,Seedor JA,McCormick SA,Milman T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To report a unique case of bilateral Chandler syndrome with recurrent band keratopathy. METHODS:This is a retrospective observational case report. RESULTS:A 39-year-old Asian man presented with progressive painless diminution of vision in both eyes for 6 years. Examination revealed diffuse corneal edema, hamm...

journal_title：Cornea

authors： Agarwal M,Dhiman R,Subramanian K

更新日期：2020-12-02 00:00:00

abstract：:Corneal intraepithelial neoplasia (CIN) is the term applied by some authors to the spectrum of disease ranging from mild dysplasia to carcinoma in situ. Such lesions usually are associated with dysplastic or neoplastic processes at the limbus or adjacent conjunctiva; isolated corneal dysplasia is rare. Clinically, CIN...

journal_title：Cornea

authors： Brown HH,Glasgow BJ,Holland GN,Foos RY

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:The goal of this study was to prospectively assess the deep lamellar endothelial keratoplasty (DLEK) wound anatomy and its evolution during the 12 months after surgery, using optical coherence tomography (OCT). METHODS:The eyes of 8 patients (1 eye per patient) who consecutively underwent DLEK for Fuchs dystro...

journal_title：Cornea

authors： Ferré LA,Nada O,Sherknies D,Boisjoly H,Brunette I

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To present a novel apparatus for simulating the anterior and posterior segment pressure dynamics involved in executing Descemet membrane endothelial keratoplasty (DMEK) surgery when using a chamber-shallowing technique. METHODS:An artificial anterior chamber (AAC), 18-mm trephine, latex glove, two 3-mL syringe...

journal_title：Cornea

authors： Sáles CS,Straiko MD,Fernandez AA,Odell K,Dye PK,Tran KD

更新日期：2018-02-01 00:00:00

abstract：:Persistent donor corneal epithelial defects following penetrating keratoplasty may lead to graft failure. We herein describe a method for providing corneal protection using a temporary suture tarsorrhaphy. This technique is simple and completely reversible, and it allows continued observation and instillation of topic...

journal_title：Cornea

authors： Koenig SB,Harris GJ

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:To describe the technique and outcomes of limbal stem cell-sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). METHODS:In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patient...

journal_title：Cornea

authors： Karimian F,Baradaran-Rafii A,Faramarzi A,Akbari M

更新日期：2014-01-01 00:00:00

abstract：:The authors sought to determine whether adenovirus could infect human corneal epithelium in vivo. They reviewed the medical records of six patients with adenovirus-positive viral corneal cultures who were examined at the Bascom Palmer Eye Institute between March 21, 1986, and December 31, 1992. The six patients with a...

journal_title：Cornea

authors： Chodosh J,Miller D,Stroop WG,Pflugfelder SC

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:Patients undergoing primary pterygium excision with autologous conjunctival autograft and human tissue adhesive in New Zealand, currently receive subconjunctival anesthesia with oral postoperative analgesia for pain. Our aim was to investigate the potential added benefit of intraoperative subtenon bupivacaine t...

journal_title：Cornea

authors： Bhikoo R,Hughes K,Vather R,Murphy C

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To present a case series of patients with Boston keratoprosthesis type I (KPro) who have had successful ptosis repair with Müller muscle-conjunctiva resection (MMCR). METHODS:Patients with KPros managed with MMCR for ptosis were identified. Records were examined to obtain preoperative and postoperative visual ...

journal_title：Cornea

authors： Lim JM,Bang GM,Cortina MS,de la Cruz J,Setabutr P

更新日期：2014-03-01 00:00:00

abstract：:Infectious keratitis after penetrating keratoplasty can be devastating to the survival of the graft and its visual outcome. From November 1989 to October 1994, we treated 41 episodes of late microbial keratitis among 354 consecutive penetrating keratoplasty patients and reviewed their medical records retrospectively. ...

journal_title：Cornea

authors： Tseng SH,Ling KC

更新日期：1995-11-01 00:00:00

abstract：PURPOSE:To evaluate long-term follow-up of high-risk corneal transplants allocated after matching for broad HLA-A and HLA-B antigens and to establish whether matching for HLA-A and -B antigen "splits" would result in a reduced risk of immunologic graft failure. METHODS:A total of 303 high risk corneal transplants was ...

journal_title：Cornea

authors： Bartels MC,Doxiadis II,Colen TP,Beekhuis WH

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:To report a case of Alternaria alternata keratitis analyzed with in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (OCT). METHODS:A 68-year-old man with unilateral keratitis was evaluated using IVCM (Heidelberg Retina Tomograph II; Heidelberg, Germany) and anterior segment OC...

journal_title：Cornea

authors： Martone G,Pichierri P,Franceschini R,Moramarco A,Ciompi L,Tosi GM,Balestrazzi A

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:To report the clinical impact of conjunctivochalasis on the ocular surface by evaluating the effect of a new concept of conjunctivochalasis operation on the resolution of patients' symptoms and corneal epithelial damage. Also, the association of inflammation with conjunctivochalasis is examined. PATIENTS AND M...

journal_title：Cornea

authors： Yokoi N,Komuro A,Nishii M,Inagaki K,Tanioka H,Kawasaki S,Kinoshita S

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To report the outcomes of Boston keratoprosthesis (K-pro) type I implantation for congenital aniridia. METHODS:A retrospective review of the medical records of every patient with congenital aniridia who underwent Boston K-pro type I implantation at the University of Iowa Hospitals and Clinics from January 1, 2...

journal_title：Cornea

authors： Rixen JJ,Cohen AW,Kitzmann AS,Wagoner MD,Goins KM

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To measure corneal epithelial thickness (CET) in patients with glaucoma using anterior-segment optical coherence tomography and to evaluate CET changes in relation to corneal epithelial microvilli analyzed by scanning electron microscopy (SEM). METHODS:Twenty-two eyes (16 patients) being treated with preservat...

journal_title：Cornea

authors： Cennamo G,Montorio D,Del Prete S,Del Prete A,Cennamo G

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To report eyes with keratoconus that progressed during pregnancy. METHODS:Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was docu...

journal_title：Cornea

authors： Bilgihan K,Hondur A,Sul S,Ozturk S

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:The shape and position of the eyelids affect corneal topography. This study evaluated preoperative and postoperative corneal topography in involutional ectropion of the lower eyelid. METHODS:Eighteen patients with unilateral involutional lower eyelid ectropion underwent ophthalmic examinations and corneal topo...

journal_title：Cornea

authors： Detorakis ET,Ioannakis K,Kozobolis VP

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:To evaluate the incidence, clinical course, and management of fungal interface keratitis (IK) after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This is a single-center retrospective observational case series of 3950 eyes undergoing DMEK. Six eyes with fungal IK were detected and analyzed. Analys...

journal_title：Cornea

authors： Augustin VA,Weller JM,Kruse FE,Tourtas T

更新日期：2018-11-01 00:00:00

abstract：:The cell culture method was used to quantitatively evaluate the cytotoxicity to porcine corneal endothelial cells by drugs in the usual concentrations of intracameral injections (ICI). Time-dependent cytotoxicity of drugs was evaluated quantitatively; dye exclusion assay by trypan blue was used as a viability assay; a...

journal_title：Cornea

authors： Chang CH,Lin CP,Wang HZ

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To develop a new rabbit model of corneal endothelial injury using a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser. METHODS:The corneal endothelia of 2 groups of New Zealand white rabbits were treated with an Nd:YAG laser in a uniformly scattered fashion. Rabbits in group A underwent laser burns on the...

journal_title：Cornea

authors： Zhang W,Hu Y,Lu L,Liu Y,Yang X,Sun H,Ruan J,Chen J,Yao Q,Yan C,Gu P,Fu Y,Shao C,Fan X

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the association between a Mediterranean dietary pattern (MeDi) and Vitamin D levels on dry eye syndrome (DES). METHODS:This was a cross-sectional study. Male patients seen in the Miami Veterans Affairs eye clinic with normal eyelid, corneal, and conjunctival anatomy were r...

journal_title：Cornea

authors： Galor A,Gardener H,Pouyeh B,Feuer W,Florez H

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To report a case of possible iatrogenic Creutzfeldt-Jakob many years following penetrating keratoplasty. DESIGN:Observational case report. METHODS:We reviewed the patient's chart, available literature on Creutzfeldt-Jakob disease, and current recommendations from the Eye Bank of America Association. RESULT...

journal_title：Cornea

authors： Hammersmith KM,Cohen EJ,Rapuano CJ,Laibson PR

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:Corneal transplantation is the standard of care for pediatric corneal opacities, but little consensus exists on optimal surgical management. Our goal was to evaluate cross-sectional data of donor and recipient characteristics collected from eye banks providing tissue for pediatric corneal transplant cases to as...

journal_title：Cornea

authors： Zhu AY,Prescott CR

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To report a case of delayed bilateral Descemet's detachment with spontaneous resolution in one eye following successful treatment of the fellow eye. METHOD:Case report. RESULTS:A 78-year-old male who underwent uncomplicated bilateral cataract extraction with phacoemulsification developed delayed bilateral Des...

journal_title：Cornea

authors： Couch SM,Baratz KH

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To investigate the clinical features and outcomes for conjunctival melanoma based on patient age. METHODS:A retrospective review of patients with conjunctival melanoma managed at a single tertiary referral center from April 18, 1974, to September 9, 2019. Clinical features and outcomes were compared by patient...

journal_title：Cornea

authors： Dalvin LA,Yaghy A,Vaidya S,Pacheco RR,Perez AL,Lally SE,Shields JA,Shields CL

更新日期：2020-07-30 00:00:00

abstract：PURPOSE:Peters anomaly is the most common cause of congenital corneal opacities. Although conservative management is often ineffective except in mild cases, surgical intervention in the form of penetrating keratoplasty is fraught with unpredictability and often has unacceptable postoperative outcomes. As such, there is...

journal_title：Cornea

authors： Soh YQ,Mehta JS

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients with type 2 diabetes mellitus. METHODS:Patients with type 2 diabetes without diabetic retinopathy (DR) (n = 54), with nonproliferative DR (n = 45), with proliferative DR (PDR) (n = 25), and controls (n = 4...

journal_title：Cornea

authors： Baek J,Doh SH,Chung SK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To evaluate and compare corneal higher-order aberrations (HOAs) after Descemet stripping automated endothelial keratoplasty (DSAEK), femtosecond laser-assisted penetrating keratoplasty (FLAK), and conventional penetrating keratoplasty (PKP). METHODS:A retrospective comparison of consecutive surgical series of ...

journal_title：Cornea

authors： Chamberlain W,Omid N,Lin A,Farid M,Gaster RN,Steinert RF

更新日期：2012-01-01 00:00:00