Subconjunctival bevacizumab for corneal neovascularization.

abstract：PURPOSE:To assess the relationship between corneal thinning measured by clinician-graded slit-lamp examination compared with ultrasound pachymetry (USP), anterior segment optical coherence tomography (AS-OCT), and the Pentacam. METHODS:Patients with corneal thinning underwent USP, AS-OCT, Pentacam measurements and sta...

journal_title：Cornea

authors： Oatts JT,Keenan JD,Mannis T,Lietman TM,Rose-Nussbaumer J

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

journal_title：Cornea

authors： Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To report keratouveitis arising from corneal penetration by a bristle worm seta (bristle). METHODS:We report on a 64-year-old woman presenting with uniocular pain, redness, reduced vision, discharge, and pustular rash of the hands after cleaning out her marine aquarium containing bristle worms and rubbing her ...

journal_title：Cornea

authors： Kirk J,Gunn D,Wong N,Minchin E,Darcy K

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...

journal_title：Cornea

authors： El-Massry AA,Goweida MB,Shama Ael-S,Elkhawaga MH,Abdalla MF

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To determine if concurrent use of 5% natamycin and 2% econazole offers greater benefits than monotherapy with 5% natamycin for the management of fungal keratitis. METHODS:Subjects presenting to the cornea service were treated with 5% natamycin and 2% econazole used concurrently. We compared the results with a ...

journal_title：Cornea

authors： Prajna NV,Nirmalan PK,Mahalakshmi R,Lalitha P,Srinivasan M

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To report the use of anterior stromal micropuncture and amniotic membrane transplantation in the management of painful bullous keratopathy in patients with poor visual potential. METHODS:Interventional case series. A retrospective review was performed to identify all patients who were treated by one of us (A.J...

journal_title：Cornea

authors： Sonmez B,Kim BT,Aldave AJ

更新日期：2007-02-01 00:00:00

abstract：:Persistent donor corneal epithelial defects following penetrating keratoplasty may lead to graft failure. We herein describe a method for providing corneal protection using a temporary suture tarsorrhaphy. This technique is simple and completely reversible, and it allows continued observation and instillation of topic...

journal_title：Cornea

authors： Koenig SB,Harris GJ

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...

journal_title：Cornea

authors： Lee YC,Kim SY

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To describe a distinct and unusual superficial dendriform keratopathy that can be seen in postkeratoplasty eyes. METHOD:Three Caucasian women in their sixth decade of life were referred to the Corneal and External Disease Service at the University of California, Davis, and underwent penetrating keratoplasty fo...

journal_title：Cornea

authors： Mannis MJ,Garcia-Ferrer FJ,Davitt S

更新日期：1998-05-01 00:00:00

abstract：PURPOSE:To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS:A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by con...

journal_title：Cornea

authors： Witherspoon SR,Hogan RN,Petroll WM,Mootha VV

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:To evaluate and report the efficacy of fibrin glue (FG)-assisted augmented amniotic membrane transplantation (AMT) in patients with large corneal perforations. METHODS:In a retrospective case series, 10 patients with corneal perforations more than 2 mm in diameter were treated with "FG-assisted augmented AMT."...

journal_title：Cornea

authors： Kim HK,Park HS

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To test whether verteporfin with a nonthermal laser increases corneal mechanical stiffness and resistance to enzymatic degradation ex vivo. METHODS:Thirty human corneas (n = 5 per group) were treated with verteporfin alone (V), irradiated with nonthermal laser therapy (689 nm) alone (NTL), or received combined...

journal_title：Cornea

authors： Alageel SA,Arafat SN,Salvador-Culla B,Kolovou PE,Jahanseir K,Kozak A,Braithwaite GJC,Ciolino JB

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of corneal cross-linking (CXL; riboflavin/ultraviolet A) as a simple therapy for Acanthamoeba keratitis. METHODS:Twenty rabbits were systemically anesthetized and the stroma of their right corneas was inoculated with a suspension of Acanthamoeba. Rabbits were divided into 2 groups: one...

journal_title：Cornea

authors： Berra M,Galperín G,Boscaro G,Zarate J,Tau J,Chiaradia P,Berra A

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:The normal cornea is devoid of blood and lymphatic vessels but can become vascularized secondary to a variety of corneal diseases and surgical manipulations. Whereas corneal (hem)angiogenesis, i.e., the outgrowth of new blood vessels from preexisting limbal vessels, is obvious both clinically and histologically...

journal_title：Cornea

authors： Cursiefen C,Chen L,Dana MR,Streilein JW

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To compare the incidence of corneal epithelial ingrowth (EIG) and the visual outcomes of enhancement with laser in situ keratomileusis (LASIK) by flap lift when a bandage soft contact lens (CL) was fitted after the procedure and when it was not. METHODS:This is a multicenter, retrospective, interventional case...

journal_title：Cornea

authors： Ortega-Usobiaga J,Baviera-Sabater J,Llovet-Osuna F,González-López F,Bilbao-Calabuig R,Llovet-Rausell A,Beltrán-Sanz J

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To describe a new method of visualizing human conjunctiva goblet cell mucin secretion by using a combination of impression cytology and laser scanning microscopy. METHODS:By assembling a Z-stack of confocal microscopy images taken from human impression cytology samples, we obtained 3-dimensional information ab...

journal_title：Cornea

authors： Peral A,Pintor J

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To compare acid-base and oxidation-reduction indicators and to investigate the effect of buffer and temperature on the colorimetric detection of microbial growth in corneal preservation media. METHODS:Corneal preservation media containing gentamicin, without or with HEPES buffer, were prepared with either phen...

journal_title：Cornea

authors： Chu YI,Penland RL,Wilhelmus KR

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:To review the incidence, distribution, current trends, and resistance patterns of bacterial keratitis isolates in Toronto over the past 16 years. METHODS:Microbiology records of suspected bacterial keratitis that underwent a diagnostic corneal scraping and cultures from January 1, 2000, through December 31, 20...

journal_title：Cornea

authors： Tam ALC,Côté E,Saldanha M,Lichtinger A,Slomovic AR

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To investigate the safety of intracameral injection of minimum bactericidal concentration (MBC) of povidone iodine (PI) on the corneal endothelium in a rabbit model as a proposed method of prophylaxis against postoperative endophthalmitis. METHODS:We included 32 New Zealand white rabbits in the study. Twenty-f...

journal_title：Cornea

authors： ElKitkat RS,Ebeid WM,Habib EK,Shoukry Y

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...

journal_title：Cornea

authors： Smolek MK

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To present the clinical outcome of 2 cases of severe dry eye associated with Nivolumab, with 1 case progressing to corneal perforation. DESIGN:Case report. CASE 1:: A 58-year-old man with metastatic melanoma was referred for the management of severe bilateral dry eyes after undergoing his sixth cycle of Nivol...

journal_title：Cornea

authors： Nguyen AT,Elia M,Materin MA,Sznol M,Chow J

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate the intraocular pressure (IOP) with three different instruments, Goldmann applanation tonometer (GAT), noncontact tonometer, and Tono-Pen after photorefractive keratectomy (PRK) for myopia. METHODS:A prospective case series study to evaluate preoperative and postoperative IOP measurements of 149 ey...

journal_title：Cornea

authors： Garzozi HJ,Chung HS,Lang Y,Kagemann L,Harris A

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To examine the efficacy of corneal collagen cross-linking (CXL) for the treatment of keratoconus (KCN). METHODS:A systemic literature review and meta-analysis of ocular functional and structural parameters of patients with KCN undergoing cross-linking procedures were performed using PubMed and the web of scien...

journal_title：Cornea

authors： Meiri Z,Keren S,Rosenblatt A,Sarig T,Shenhav L,Varssano D

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:Previous work has suggested that Descemet membrane (DM) folds arise in response to corneal swelling. However, their origin has not been closely explored. In this study, we used optical coherence tomography to evaluate whether DM folds arise secondary to folds in the middle stroma. METHODS:Serial optical cohere...

journal_title：Cornea

authors： Annadanam A,Stoeger CG,Galloway JD,Hikes MT,Jun AS

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To study the possible changes in Scheimpflug corneal densitometry 6 months after mitomycin C-augmented trabeculectomy and to compare these measurements with healthy controls. METHODS:Corneal densitometry was monitored with the Pentacam HR3 before and 6 months after first-time uncomplicated mitomycin C-augmente...

journal_title：Cornea

authors： Pillunat KR,Orphal J,Haase M,Pillunat LE,Herber R

更新日期：2020-07-27 00:00:00

abstract：PURPOSE:The 27-kDa heat shock protein (HSP27) has been implicated in wound healing in multiple tissues. We investigated the expression and localization of phosphorylated HSP27 during epithelial wound healing in the murine cornea. METHODS:Corneas of 8- to 10-week-old C57BL6 mice were wounded by epithelial debridement (...

journal_title：Cornea

authors： Jain S,De la Cruz J,Kang E,Kojima T,Chang JH,Kim JY

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To describe a case of Beauveria bassiana keratitis and to discuss the management of this rare condition. METHODS:An 82-year-old woman underwent surgical repair of a graft wound dehiscence. Seven months later, shortly after the removal of sutures, the patient developed a fungal keratitis. B. bassiana was identi...

journal_title：Cornea

authors： Kisla TA,Cu-Unjieng A,Sigler L,Sugar J

更新日期：2000-05-01 00:00:00

abstract：:The mechanism of ocular surface allergy in the forms of atopic conjunctivitis and vernal keratoconjunctivitis has been highlighted by specific functions of chemokines. In the context of late-phase allergic responses, these molecules have key roles in recruitment and activation of leukocytes. Their interaction with lig...

journal_title：Cornea

authors： Miyazaki D,Nakamura T,Komatsu N,Nawata N,Ikeda Y,Inoue Y,Higashi H,Ono SJ

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare the effect of chloramphenicol eye drops or ointment, high-concentration hyaluronic acid, or no treatment on reepithelialization of corneal erosions in an experimental model. METHODS:Uniform 6-mm corneal erosions were created in 23 rabbit eyes. The rabbits were randomized to...

journal_title：Cornea

authors： Barequet IS,Harizman N,Ziv H,Rosner M

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:Sequential therapeutic penetrating keratoplasty (TPK) using a cryopreserved cornea followed soon after by a fresh optical grade cornea for severe infectious keratitis may improve the survival of the optical graft. The aim of this study was to compare the therapeutic efficacy, visual outcomes, and graft survival...

journal_title：Cornea

authors： Lim LS,Arundhati A,Tan DT

更新日期：2011-07-01 00:00:00