Abstract:
PURPOSE:To describe the histopathologic characteristics of a 51-year-old Castroviejo square graft that remained functional for more than 50 years and to describe the wound-healing characteristics over this period of time. METHODS:An 80-year-old woman with a history of keratoconus underwent penetrating keratoplasty with square grafts in 1956 and 1957 in the right and left eyes, respectively. The graft from the right eye was replaced in 2007, and the corneal specimen was submitted for histopathologic analysis. RESULTS:Light microscopy demonstrated a smooth transition between host and donor stroma. Descemet's membrane was markedly thickened (>40 m) and laminated, and a very thin retrocorneal membrane was visible at high magnification. CONCLUSIONS:This case provides an opportunity to observe the histopathology of corneal wound healing over a period of more than half a century.
journal_name
Corneajournal_title
Corneaauthors
Graue-Hernández EO,Harocopos G,Bradley JC,Smith ME,Mannis MJdoi
10.1097/ICO.0b013e3181861cb2subject
Has Abstractpub_date
2009-04-01 00:00:00pages
345-7issue
3eissn
0277-3740issn
1536-4798pii
00003226-200904000-00018journal_volume
28pub_type
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