The castroviejo square graft: wound healing after 51 years.

Abstract:

PURPOSE:To describe the histopathologic characteristics of a 51-year-old Castroviejo square graft that remained functional for more than 50 years and to describe the wound-healing characteristics over this period of time. METHODS:An 80-year-old woman with a history of keratoconus underwent penetrating keratoplasty with square grafts in 1956 and 1957 in the right and left eyes, respectively. The graft from the right eye was replaced in 2007, and the corneal specimen was submitted for histopathologic analysis. RESULTS:Light microscopy demonstrated a smooth transition between host and donor stroma. Descemet's membrane was markedly thickened (>40 m) and laminated, and a very thin retrocorneal membrane was visible at high magnification. CONCLUSIONS:This case provides an opportunity to observe the histopathology of corneal wound healing over a period of more than half a century.

journal_name

Cornea

journal_title

Cornea

authors

Graue-Hernández EO,Harocopos G,Bradley JC,Smith ME,Mannis MJ

doi

10.1097/ICO.0b013e3181861cb2

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

345-7

issue

3

eissn

0277-3740

issn

1536-4798

pii

00003226-200904000-00018

journal_volume

28

pub_type

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