Abstract：
:While for many allergens a dose-response relationship has clearly been established the association between early childhood exposure to cat allergens and risk of sensitisation is still controversial and even inverse relations have been described. At the same time, a negative association between Toxoplasma gondii (T. gondii) infection and atopic diseases has been found in epidemiologic studies. As cats are the major source of T. gondii oocysts, we hypothesize that cat allergen exposure might be a confounder in the association between T. gondii infection and allergic diseases. Furthermore, it is well known that atopic diseases are T helper cell 2 (Th2) driven while autoimmune diseases are dominated by a Th1 response. A counterbalance between Th1 and Th2 cells has been postulated. However, it has been shown recently that subjects with autoimmune disease are more likely to suffer from atopic diseases. Therefore, similar cytokine profiles might underlie these disorders. If this holds true it can be hypothesised that T. gondii infection is associated with a lower prevalence of autoimmune disease.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Radon K,Dressel H,Windstetter D,Reichert J,Schmid M,Nowak Dsubject
Has Abstractpub_date
2003-04-30 00:00:00pages
147-53issue
4eissn
0949-2321issn
2047-783Xjournal_volume
8pub_type
杂志文章abstract：INTRODUCTION:Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-methionine breath test (...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-16-6-258
更新日期：2011-06-21 00:00:00
abstract：BACKGROUND:Osteoporosis affects 200 million people worldwide and places an enormous economic burden on society. We aim to identify the feature genes that are related to osteoprotegerin in osteoporosis and to perform function analysis with DNA microarray from human bone marrow. METHODS:We downloaded the gene expression...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783X-18-15
更新日期：2013-06-03 00:00:00
abstract：OBJECTIVE:The influence of cytomechanical forces in cellular migration, proliferation and differentiation of mesenchymal stem cells (MSCs) is still poorly understood in detail. METHODS:Human MSCs were isolated and cultivated onto the surface of a 3 x 3 mm porcine collagen I / III carrier. After incubation, cell cultur...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-1-35
更新日期：2010-01-29 00:00:00
abstract：BACKGROUND:Increasing rates of prosthetic joint infection (PJI) have presented challenges for general practitioners, orthopedic surgeons and the health care system in the recent years. The diagnosis of PJI is complex; multiple diagnostic tools are used in the attempt to correctly diagnose PJI. Evidence-based algorithms...
journal_title：European journal of medical research
pub_type： 杂志文章,meta分析
doi：10.1186/s40001-017-0245-1
更新日期：2017-03-09 00:00:00
abstract：:To investigate Candida epidemiology and immunologic correlates of protection in HIV-1 infected patients, we analyzed oral Candida colonization in correlation to the Candida-specific T-cell response measured by g-IFN ELISPOT using different Candida (C.) albicans strains. In 16/46 patients (13 asymptomatic, 3 with oral ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2006-11-30 00:00:00
abstract：:Exposure to high concentrations of oxygen is known to induce changes in lung function through effects on several pulmonary cell types, including alveolar macrophages (AM). In this study, we studied the in vitro effects of hyperoxia on the release of proinflammatory cytokines and the expression of surface receptors in ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-04-21 00:00:00
abstract：:Photoplethysmography enables non-invasive investigation of the volume pulse in the microvasculature of patients. We previously have shown that time-discrete analysis enables identification of highly reproducible characteristics of the volume pulse in absolute values. The method would be of particular interest, if the ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1998-05-12 00:00:00
abstract：:In ten cystic fibrosis patients and nine age-matched controls, renal function was determined before and after infusion of secretin. Under baseline conditions creatinine excretion and clearance were significantly elevated, exclusively due to those patients who were homozygous for the DF508 mutation (153 vs 132 ml/min*1...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-10-30 00:00:00
abstract：:Possible effects of electromagnetic fields on human brain activity were studied. In a single-blind, cross-over-designed and placebo-controlled study 36 volunteers were exposed firstly to an electromagnetic field originating form a MediLine "MEGA-WAVE 150/1" therapy instrument and secondly to a field originating from a...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-10-16 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the impact of diosgenin, an important monomer of sapogenins in yams, on ovarian reserve in a natural aging mice model. STUDY DESIGN:This randomized controlled trial included 60 9-month-old C57 naturally aging female mice. Twenty-one mice were assigned to the dio grou...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-017-0285-6
更新日期：2017-10-18 00:00:00
abstract：:Hemorrhage from esophageal varices is a life-threatening event in patients with liver cirrhosis. About 40% to 80% of the patients surviving the first bleeding suffer from a recurrence of variceal bleeding within one year. This high recurrence rate substantially contributes to the mortality in patients with liver cirrh...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-25 00:00:00
abstract：BACKGROUND:The pathogenesis of central retinal artery occlusions (CRAO) varies, depending upon the underlying disease. An embolic origin of an occlusion often occurs. PATIENT AND METHODS:A 50-year-old man with an occlusion of the left internal carotid artery was examined because of a left central retinal artery occlus...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2000-04-19 00:00:00
abstract：BACKGROUND:Patients with human immunodeficiency virus (HIV) infection have an increased risk of cardiovascular diseases. Previous publications described pericardial effusion as one of the most common HIV-associated cardiac affiliations. The aim of the current study was to investigate if pericardial effusion still has a...
journal_title：European journal of medical research
pub_type： 杂志文章,多中心研究
doi：10.1186/2047-783x-16-11-480
更新日期：2011-11-10 00:00:00
abstract：BACKGROUND:Coronavirus is challenging the global health care system from time to time. The pregnant state, with alterations in hormone levels and decreased lung volumes due to a gravid uterus and slightly immunocompromised state may predispose patients to a more rapidly deteriorating clinical course and can get a great...
journal_title：European journal of medical research
pub_type： 杂志文章,meta分析
doi：10.1186/s40001-020-00439-w
更新日期：2020-09-04 00:00:00
abstract：BACKGROUND:Current evidence regarding the prognostic relevance of urinary sodium-to-potassium ratio (Na-to-K ratio), as an indicator of diet quality is limited. This study was conducted to investigate whether urinary Na-to-K ratio could be related to habitual dietary patterns, in a general population. METHODS:This stu...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-020-00476-5
更新日期：2021-01-06 00:00:00
abstract：:In the course of infection by the Human Immunodeficiency Virus (HIV) typical changes of inflammatory periodontal diseases can arise. The prevalence of these illnesses may be up to 5%. The HIV-associated periodontal diseases include linear gingival erythema (LGE), necrotizing ulcerative gingivitis (NUG) and necrotizing...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-26 00:00:00
abstract：BACKGROUND:Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing models are needed in order to develop approaches to overcome chemoresistance. - METHODS:Ten human ce...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-8-337
更新日期：2010-08-20 00:00:00
abstract：BACKGROUND:A novel software ("Dynamic Coronary Roadmap") was developed, which offers a real-time, dynamic overlay of the coronary tree on fluoroscopy. Once the roadmap has been automatically generated during angiography it can be used for navigation during percutaneous coronary interventions (PCI). As a feasibility stu...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-018-0333-x
更新日期：2018-07-31 00:00:00
abstract：BACKGROUND:Prosthetic joint infection (PJI) is a serious complication of orthopedic implant surgery. Treatment often includes the use of an antibiotic-loaded Polymethyl methacrylate (PMMA) bone cement spacer. Several antibiotics are commonly used for the preparation of these spacers, but due to the increasing number of...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-020-00428-z
更新日期：2020-08-18 00:00:00
abstract：AIM:Antiseptics are commonly used in clinical practice to disinfect tissue and to avoid infections. However, topical antiseptics are assumed to have an influence on skin microcirculation, per se. Thus, the aim of the study was to analyse the influence of topically applied antiseptics on the microcirculation of intact s...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2004-09-29 00:00:00
abstract：:Antibiotic-resistant organisms causing both hospital- and community-acquired complicated skin and soft-tissue infections (cSSTI) are increasingly reported. A substantial medical and economical burden associated with MRSA colonisation or infection has been documented. The number of currently available appropriate antim...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/2047-783x-15-12-554
更新日期：2010-11-30 00:00:00
abstract：BACKGROUND:In pursuit of improvement in cardiopulmonary resuscitation (CPR), new technologies for the measurement and assessment of CPR quality are implemented. In our study, we assessed the kinematics of the rescuer during continuous chest compression (CCC-CPR). The proper performance of the procedure is a survival pr...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-019-0369-6
更新日期：2019-02-08 00:00:00
abstract：:Infant formulas containing medium chain triglycerides (MTC) have been used for the nutritional management of infants with fat malabsorption. The optimal proportion of MTC in the formula remains to be determined. Three infant formulas with varying proportion of MTC in the fat blend were studied in children with cystic ...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1997-02-21 00:00:00
abstract：INTRODUCTION:Azathioprine has variable efficacy in inflammatory bowel disease. Previous studies suggested that either neutropenia, an increase in the mean corpuscular volume, the assessment of thiopurine methyl-transferase activity or erythrocyte 6-thioguanine values might predict the treatment response. However, due t...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：2005-12-07 00:00:00
abstract：:Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the product of alternative RNA splicing of db gene. According to its structural differences, the receptor's isoforms are divided into three classes: long, short, and secretory isoforms. A long, fully ...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/2047-783x-15-s2-50
更新日期：2010-11-04 00:00:00
abstract：BACKGROUND:Electroacupuncture is well known for its advantageous neuroanalgesic and therapeutic effects on myocardial ischemia-reperfusion injury. The purpose of the present research was to verify whether electroacupuncture can alleviate bupivacaine-induced myocardial injury. METHODS:Specific pathogen-free Wistar rats...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-020-00431-4
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Multiple severe trauma frequently leads to massive dysbalances of the human immune system. This phenomenon is known as "Systemic Inflammatory Response Syndrome (SIRS)". SIRS is connected to multiple organ failure and thereby entails higher morbidity and mortality in trauma patients. Pro- and anti-inflammator...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-14-7-284
更新日期：2009-07-22 00:00:00
abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by T-cell-dependent B-cell activation and altered T-cell response. Co-stimulatory and co-inhibitory molecules regulate and exert T-cell differentiation, survival and cytokine production. CD134+ and PD-1+ T-cells in SLE patients are inc...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-019-0385-6
更新日期：2019-07-22 00:00:00
abstract：:The influence of heparin on Polymorphonuclear (PMN s) leukocytes was investigated using a new whole-blood cytofluorometric method (patent granted for the test with the number P 4334935.8-41) with Candida albicans and Staphylococcus aureus as test microorganisms. After comparing the effect of equal volumes of two widel...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-12-31 00:00:00
abstract：:Pentalogy of Fallot is a rare cyanotic congenital heart disease characterized by biventricular origin of the aorta above a large ventricular septal defect, obstruction of the pulmonary outflow, right ventricular hypertrophy (tetralogy of Fallot), and an atrial septal defect. Mortality due to syncope, arrhythmia or con...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2001-06-28 00:00:00
