Abstract:
:Event-related potentials (ERPs) were measured from 24 chronic closed head injury (CHI) patients and 18 age- and education-matched controls. The oddball paradigm was applied while subjects were watching a silent movie. The standard (p=0.8) sound of 75 ms duration had a basic frequency of 500 Hz with harmonic partials of 1000 Hz and 1500 Hz, whereas these frequencies for the pitch deviant were each 10% higher. The frequencies of the duration deviant matched with those of the standard but was 25 ms in duration. The MMN (mismatch negativity), generated by the brain's automatic auditory change-detector mechanism, was elicited by both deviants. No significant differences in the MMN latency or amplitude for either pitch or duration deviants were found between the groups. However, the MMN amplitude for the pitch deviant decreased in the patient group during the experiment considerably faster than in controls, suggesting a faster vigilance decrement in the patients.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Kaipio ML,Novitski N,Tervaniemi M,Alho K,Ohman J,Salonen O,Näätänen Rdoi
10.1097/00001756-200105250-00043subject
Has Abstractpub_date
2001-05-25 00:00:00pages
1517-22issue
7eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::The effect of olfactory deprivation on cellular expression of the Bcl-2 gene in the olfactory bulb of young rats was investigated. Restriction of olfactory stimuli caused an overall increase in Bcl-2 mRNA expression, with increases seen in the lateral aspects of glomerular, external plexiform, mitral and granule cell ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1995-12-29 00:00:00
abstract::Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199710200-00011
更新日期:1997-10-20 00:00:00
abstract::Subcortical visual inputs to motion-selective cortex in primates survive after damage to the primary visual cortex (area 17/V1). Activation of human motion cortex was examined using scalp electrodes in a V1-damaged hemianope. Blind field motion-onset visual evoked potentials (VEPs) shared many of the characteristics a...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199911260-00024
更新日期:1999-11-26 00:00:00
abstract::Neuroblastoma is an important problem in children. Long noncoding RNAs (lncRNAs) exhibit important roles in tumorigenicity of neuroblastoma. However, the role and mechanism of lncRNA small nucleolar RNA host gene 16 (SNHG16) in neuroblastoma tumorigenicity remain poorly understood. Forty-six neuroblastoma samples and ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001537
更新日期:2020-12-09 00:00:00
abstract::The hypothesis that sleep participates in the consolidation of recent memory traces has been investigated using four main paradigms: (1) effects of post-training sleep deprivation on memory consolidation, (2) effects of learning on post-training sleep, (3) effects of within sleep stimulation on the sleep pattern and o...
journal_title:Neuroreport
pub_type: 杂志文章,评审
doi:10.1097/00001756-200112210-00001
更新日期:2001-12-21 00:00:00
abstract::Fluoxetine, a serotonin-selective reuptake inhibitor, exerts antidepressant and antianxiety effects on major depressive and anxiety disorders. Previous studies suggest that treatment with fluoxetine influences the expression of various proteins that are involved in proliferation, differentiation, and apoptosis in the ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000284
更新日期:2014-12-03 00:00:00
abstract::Nitric oxide (NO), a free radical gas that acts as a neural messenger, is produced from L-arginine by the enzyme nitric oxide synthase (NOS). The present study describes the autoradiographic localization throughout rat brain of the binding of [3H]L-NG-nitro-arginine ([3H]L-NOARG), a reversible NOS inhibitor, and confi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199510020-00005
更新日期:1995-10-02 00:00:00
abstract::Activated NF-kappaB contributes to cerebral infarction by triggering a neuro-inflammatory response. Rats subjected to 90min middle cerebral artery occlusion developed a cortical infarct of 20+/-4% of hemispheric volume (n = 8). Treatment with the proteasome inhibitor CVT-634 resulted in a significantly smaller infarct...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200002070-00041
更新日期:2000-02-07 00:00:00
abstract::The neurotrophin-inducible gene VGF plays an important role in the maintenance of organismal energy balance and in the mediation of hippocampal synaptic activity. The regulatory mechanism of VGF transcription is not fully understood. The neuron-restrictive silencer factor (NRSF) binds with the neuron-restrictive silen...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000316
更新日期:2015-02-11 00:00:00
abstract::Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200402090-00001
更新日期:2004-02-09 00:00:00
abstract::We used isolated IgG antibodies selective for P2X3 receptors to study the ultrastructural distribution of these receptors in rat sensory neurons. In trigeminal ganglia, P2X3 receptor immunoreactivity occurred in small and large nerve cell bodies and their processes. Endoplasmic reticulum and Golgi apparatus were heavi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199808030-00022
更新日期:1998-08-03 00:00:00
abstract::The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestati...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200001170-00002
更新日期:2000-01-17 00:00:00
abstract::We injected neural tracers into the lateral funiculus of the spinal cord in order to relate the sites of origin of the spinal projections from the mesial cortical surface with the cytoarchitectonic organization of this region. We found a close correlation between the origin sites and density of corticospinal projectio...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199412000-00035
更新日期:1994-12-20 00:00:00
abstract::5-HTt1A receptor agonists reduce the neuronal release of 5-hydroxytryptamine (5-HT) by activation of raphe 5-HT1A autoreceptors. Using in vivo microdialysis in unanesthetized rats, we show that the local application of the selective 5-HT1A receptor agonist 8-OH-DPAT decreased the 5-HT output to approximately 50% of co...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199905140-00010
更新日期:1999-05-14 00:00:00
abstract::Dichotic pitches and mistuned harmonics can each lead to the perception of one or two auditory objects. Comparison of event-related potentials for the perception of one versus two objects reveals an early negative and a late positive component. The relationship of these components with auditory segregation was further...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32832c92bf
更新日期:2009-07-01 00:00:00
abstract::Skin sensory nerve nocifensor functions were investigated non-invasively in rats by measuring neurogenic inflammation and blister healing-rate after unilateral hindlimb denervation. Axon reflexes were evoked by transdermal iontophoresis of acetylcholine (ACh) or noxious electrical stimulation (TNS). Sodium nitroprussi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199305000-00001
更新日期:1993-05-01 00:00:00
abstract::Prior work has shown that kappa opioids may attenuate the effects of analgesic mu receptor agonists in some neural circuits related to pain modulation. This study examined whether hypoalgesia following exposure to a signal for shock is attenuated by infusions of the kappa agonist U69593 into the rostral ventromedial m...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200010200-00017
更新日期:2000-10-20 00:00:00
abstract::In this study, we have identified novel splice variants of the Na+ channel alpha subunit mRNA from cultured rat astrocytes and neuroblastoma cells. These splice variants are characterized by premature truncation or deletion of a segment in the third domain of the Na+ channel alpha subunit. The expression of three spli...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199805110-00002
更新日期:1998-05-11 00:00:00
abstract::Beta-N-methylamino-L-alanine (BMAA) is a nonprotein amino acid that may be involved in neurodegenerative diseases. It is produced by a large variety of cyanobacteria and is found at high levels in the brains of Alzheimer's disease and amyotrophic lateral sclerosis patients. Although BMAA is clearly a neurotoxin, previ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328333dfd5
更新日期:2010-01-06 00:00:00
abstract::Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200410050-00018
更新日期:2004-10-05 00:00:00
abstract::Evidences in the central nervous system are in favor that adenosine under basal conditions is released by a direct excitation-secretion modality. However, till now, there is no direct evidence that adenosine is contained in synaptic vesicles. Eight synaptic vesicle fractions were recovered on a discontinuous sucrose g...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000033
更新日期:2013-12-04 00:00:00
abstract::Spinal cord injury (SCI) causes motor dysfunction and depression, which hinders the recovery of motor function. Body weight-supported treadmill training (BWSTT) should be considered an effective method for functional rehabilitation after SCI, as it is an efficacious intervention in healthcare with no side effects. Bec...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001543
更新日期:2020-12-16 00:00:00
abstract::In neonatal retinal explants cultured long-term green cones are missing. Recently it was reported that thyroid hormone beta2 receptors (TR-beta2) are essential for these green cones to differentiate. Therefore transcript level of these receptors was investigated in our mouse retinal explants. However, thyroid receptor...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200205070-00003
更新日期:2002-05-07 00:00:00
abstract::Prism adaptation reduces some symptoms of neglect; however the mechanisms underlying such changes are poorly understood. We suggest that prisms influence neglect by acting on dorsal stream circuits subserving visuomotor control, with little influence on perceptual aspects of neglect. We examined prism adaptation in th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328338592f
更新日期:2010-04-21 00:00:00
abstract::Schwann cells at the somatic neuromuscular junction possess adenosine receptors that when activated by the release of endogenous transmitter modulate quantal transmitter release. Recently, purinergic receptors have been shown to exist on Schwann cells of axon varicosities in visceral smooth muscle where they are activ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000209001.09987.77
更新日期:2006-04-03 00:00:00
abstract::Although valproate (VPA) is used widely in the treatment of bipolar mood disorder and epilepsy, the precise mechanism of action in the brain remains elusive. In this study, we investigated the effects of subchronic VPA administrations on the expression of the cyclin-dependent kinase inhibitor (Cdkn) family in the hipp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000448
更新日期:2015-10-21 00:00:00
abstract::Two well-known appetite-regulatory peptides, leptin and cocaine- and amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet known how they interact in the nucleus accumbens, an important region mediating the rewarding effects of drugs of abuse. Using th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000822
更新日期:2017-08-02 00:00:00
abstract::Latest reports suggest the involvement of insulin in modulating memory. A few published in-vitro studies favor the antidementia effect of insulin. Thus, the present study aimed to evaluate the prophylactic role of insulin and its combination with glucose and its possible mechanism(s) in an aluminum chloride (AlCl3)-in...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000799
更新日期:2017-06-14 00:00:00
abstract::In mammals, the thalamic intergeniculate leaflet (IGL) conveys behavioral (non-photic) phase-resetting information to the circadian clock of the suprachiasmatic nucleus. Here we report a 24 h fluctuation in in vivo serotonin release in the hamster IGL region, peaking at night. Novel wheel exposure at midday, a stimulu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200401190-00021
更新日期:2004-01-19 00:00:00
abstract::Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, how...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833fcba4
更新日期:2010-11-17 00:00:00