Hox C cluster genes are dispensable for overall body plan of mouse embryonic development.

abstract：:The formation of an anterior-posterior (AP) gradient of microtubules in Drosophila oocytes is essential for specification of the AP axis. Proper microtubule organization in the oocyte requires the function of serine/threonine kinase Par-1. The N1S isoform of Par-1 is enriched at the posterior cortex of the oocyte from...

journal_title：Developmental biology

authors： Tian AG,Deng WM

更新日期：2009-03-15 00:00:00

abstract：:The earliest muscle in zebrafish arises from iterated sets of two to six cells in each somite, the muscle pioneers (MP). MP develop synchronously in young trunk myotomes adjacent to the notochord, precisely where the horizontal myoseptum will form. They elongate without cell fusion and differentiate hours earlier than...

journal_title：Developmental biology

authors： Felsenfeld AL,Curry M,Kimmel CB

更新日期：1991-11-01 00:00:00

abstract：:Metazoan development involves a myriad of dynamic cellular processes that require cytoskeletal function. Nonmuscle myosin II plays essential roles in embryonic development; however, knowledge of its role in post-embryonic development, even in model organisms such as Drosophila melanogaster, is only recently being reve...

journal_title：Developmental biology

authors： Franke JD,Montague RA,Kiehart DP

更新日期：2010-09-15 00:00:00

abstract：:A cDNA of the sea urchin Strongylocentrotus purpuratus was identified as encoding polyubiquitin and used to detect a single gene with transcripts containing multiple ubiquitin coding units. Polyubiquitin transcripts exist as a 3.2-kb RNA in polyribosomes and as three higher molecular weight RNAs in purified nuclei. Th...

journal_title：Developmental biology

authors： Nemer M,Rondinelli E,Infante D,Infante AA

更新日期：1991-06-01 00:00:00

abstract：:Using lineage tracers, we recently showed dorsal and ventral ectodermal compartments along the sides of the body in chick embryos. The compartments are formed both in presumptive limb-forming regions where they position the apical ridge and also in presumptive interlimb (flank). Here we show, using a novel technique c...

journal_title：Developmental biology

authors： Altabef M,Logan C,Tickle C,Lumsden A

更新日期：2000-06-15 00:00:00

abstract：:Copyright ...

journal_title：Developmental biology

authors：

更新日期：1998-07-15 00:00:00

abstract：:Intestinal tract development is a coordinated process involving signaling among the progenitors and developing cells from all three germ layers. Development of endoderm-derived intestinal epithelium has been shown to depend on epigenetic modifications, but whether that is also the case for intestinal tract cell types ...

journal_title：Developmental biology

authors： Ganz J,Melancon E,Wilson C,Amores A,Batzel P,Strader M,Braasch I,Diba P,Kuhlman JA,Postlethwait JH,Eisen JS

更新日期：2019-11-15 00:00:00

abstract：:A series of chimeras was generated by injecting single normal, parthenogenetic, or androgenetic blastomeres carrying transgenic markers under the zona pellucida of nontransgenic eight-cell embryos. These chimeras were cultured to the blastocyst stage and sectioned, and the transgenic component was detected by in situ ...

journal_title：Developmental biology

authors： Thomson JA,Solter D

更新日期：1989-02-01 00:00:00

abstract：:The Endo16 gene codes for an RGD-containing calcium-binding protein that is found on the basal surfaces and in the extracellular matrix of cells of the invaginating archenteron during sea urchin gastrulation. Previously, we have shown that Endo16 is a single copy gene and we have determined the coding sequence and ana...

journal_title：Developmental biology

authors： Godin RE,Urry LA,Ernst SG

更新日期：1996-10-10 00:00:00

abstract：:The sea urchin sperm receptor isolated from the eggs of Strongylocentrotus purpuratus is a high molecular weight proteoglycan-like molecule. Previous studies in our laboratory suggested that the sperm receptor has two functional components, glycosaminoglycan chains that are responsible for sperm binding and polypeptid...

journal_title：Developmental biology

authors： Ruiz-Bravo N,Lennarz WJ

更新日期：1986-11-01 00:00:00

abstract：:Gene network analysis requires computationally based models which represent the functional architecture of regulatory interactions, and which provide directly testable predictions. The type of model that is useful is constrained by the particular features of developmentally active cis-regulatory systems. These systems...

journal_title：Developmental biology

authors： Bolouri H,Davidson EH

更新日期：2002-06-01 00:00:00

abstract：:In the absence of maternal expression of the pecanex gene, the embryo develops severe hyperneuralization similar to that characteristic of Notch mutant embryos. We have extended a previous molecular analysis of the chromosomal interval that encompasses pecanex by using additional deficiencies to localize the locus on ...

journal_title：Developmental biology

authors： LaBonne SG,Sunitha I,Mahowald AP

更新日期：1989-11-01 00:00:00

abstract：:In many organisms early embryogenesis is characterised by a period refractory to transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but at around eight-cell stage transcription is activated in the somatic lineage. This model suggests that histone tail modifications associated ...

journal_title：Developmental biology

authors： Wang S,Fisher K,Poulin GB

更新日期：2011-07-15 00:00:00

abstract：:To understand cell interactions during induction of skin appendages, we studied the roles of adhesion molecules N-CAM, tenascin, integrin, and fibronectin during feather development. Tenascin appeared in a periodic pattern on epithelia and was so far the earliest molecule detected in placodes. Three placode domains we...

journal_title：Developmental biology

authors： Jiang TX,Chuong CM

更新日期：1992-03-01 00:00:00

abstract：:Full-grown Xenopus oocytes, Stage VI (1200-1300 microns), undergo meiotic maturation when exposed to progesterone. Smaller stage IV (800 microns) and stage V (1000 microns) oocytes remain in prophase arrest when exposed to this steroid. The larger stage VI oocytes undergo an intracellular alkalization from 7.2 to 7.6,...

journal_title：Developmental biology

authors： Wasserman WJ,Houle JG,Samuel D

更新日期：1984-10-01 00:00:00

abstract：:A mouse mammary epithelial cell line with morphogenetic properties in vivo, Comma-Dbeta, was used to isolate and to characterize mammary progenitor cells. We found that a homogeneous cell population expressing high surface levels of stem cell antigen 1 (Sca-1) was able to give rise in vivo to ductal and alveolar struc...

journal_title：Developmental biology

authors： Deugnier MA,Faraldo MM,Teulière J,Thiery JP,Medina D,Glukhova MA

更新日期：2006-05-15 00:00:00

abstract：:In marine teleosts, the aqp1ab water channel plays a vital role in the development of the pelagic egg phenotype. However, the developmental control of aqp1ab activation during oogenesis remains to be established. Here, we report the isolation of the 5'-flanking region of the teleost gilthead seabream aqp1ab gene, in w...

journal_title：Developmental biology

authors： Zapater C,Chauvigné F,Tingaud-Sequeira A,Finn RN,Cerdà J

更新日期：2013-05-15 00:00:00

abstract：:Cellular dedifferentiation underlies topical issues in biology such as regeneration and nuclear cloning and has common features in plants and animals. In plants, this process characterizes the transition of differentiated leaf cells to protoplasts (plant cells devoid of cell walls) and is accompanied by global chromat...

journal_title：Developmental biology

authors： Grafi G,Ben-Meir H,Avivi Y,Moshe M,Dahan Y,Zemach A

更新日期：2007-06-15 00:00:00

abstract：:Mouse mammary ductal cells cultured in type I collagen gels give rise to three-dimensional multicellular outgrowths consisting of thin spikes which are often branched, and which may have pointed or blunt ends. The significance of these spikes to normal ductal morphogenesis has been unclear, since identical structures ...

journal_title：Developmental biology

authors： Daniel CW,Berger JJ,Strickland P,Garcia R

更新日期：1984-07-01 00:00:00

abstract：:Temperature sex determining species offer a model for investigating how environmental cues become integrated to the regulation of patterning genes and growth, among bipotential gonads. Manipulation of steroid hormones has revealed the important role of aromatase in the regulation of the estrogen levels involved in tem...

journal_title：Developmental biology

authors： Díaz-Hernández V,Marmolejo-Valencia A,Merchant-Larios H

更新日期：2015-12-01 00:00:00

abstract：:We cloned Xenopus Strabismus (Xstbm), a homologue of the Drosophila planar cell or tissue polarity gene. Xstbm encodes four transmembrane domains in its N-terminal half and a PDZ-binding motif in its C-terminal region, a structure similar to Drosophila and mouse homologues. Xstbm is expressed strongly in the deep cell...

journal_title：Developmental biology

authors： Goto T,Keller R

更新日期：2002-07-01 00:00:00

abstract：:Zygote arrest (Zar) proteins are crucial for early embryonic development, but their molecular mechanism of action is unknown. The Translational Control Sequence (TCS) in the 3' untranslated region (UTR) of the maternal mRNA, Wee1, mediates translational repression in immature Xenopus oocytes and translational activati...

journal_title：Developmental biology

authors： Charlesworth A,Yamamoto TM,Cook JM,Silva KD,Kotter CV,Carter GS,Holt JW,Lavender HF,MacNicol AM,Ying Wang Y,Wilczynska A

更新日期：2012-09-15 00:00:00

abstract：:Cellular interactions with laminin are important for numerous morphogenetic events. In Xenopus, the first of these is neurulation. The integrin alpha6 subunit mediates an attachment of the cells of the neural plate to the underlying basal lamina. A disruption of this interaction results in embryos that fail to neurula...

journal_title：Developmental biology

authors： Lallier TE,DeSimone DW

更新日期：2000-09-01 00:00:00

abstract：:The cranial base is a component of the neurocranium and has a central role in the structural integration of the face, brain and vertebral column. Consequently, alteration in the shape of the human cranial base has been intimately linked with primate evolution and defective development is associated with numerous human...

journal_title：Developmental biology

authors： Van Otterloo E,Feng W,Jones KL,Hynes NE,Clouthier DE,Niswander L,Williams T

更新日期：2016-07-15 00:00:00

abstract：:An understanding of heart development is critical in any systems biology approach to cardiovascular disease. The interpretation of data generated from high-throughput technologies (such as microarray and proteomics) is also essential to this approach. However, characterizing the role of genes in the processes underlyi...

journal_title：Developmental biology

authors： Khodiyar VK,Hill DP,Howe D,Berardini TZ,Tweedie S,Talmud PJ,Breckenridge R,Bhattarcharya S,Riley P,Scambler P,Lovering RC

更新日期：2011-06-01 00:00:00

abstract：:In embryos of Patella vulgata at the 32-cell stage, one of the four vegetally located macromeres makes contacts with overlying animal micromeres. As a result, this macromere (designated 3D) divides significantly later than the other macromeres and forms the mesodermal stem cell 4d. Shortly before and during this inter...

journal_title：Developmental biology

authors： Kühtreiber WM,van Dongen CA

更新日期：1989-04-01 00:00:00

abstract：:We examined the development of epithelial Na+ conductance in 6- and 7-day post coitus (p.c.) preimplantation rabbit embryos using the whole-cell patch-clamp technique on dissociated rabbit trophectodermal cells and by immunocytochemical localization using a polyclonal antibody directed against subunits of an apical ep...

journal_title：Developmental biology

authors： Robinson DH,Bubien JK,Smith PR,Benos DJ

更新日期：1991-10-01 00:00:00

abstract：:Previous studies suggest that sensory innervation of muscles is patterned by motor innervation. Muscle afferent projections mirror motor projections after various experimental manipulations and muscle afferents fail to project to muscle in the absence of motoneurons. It is not known, however, whether muscle afferents ...

journal_title：Developmental biology

authors： Wang G,Scott SA

更新日期：1997-06-01 00:00:00

abstract：:Type II collagen is a major component of hyaline cartilage, and has been suggested to be causally involved in promoting chondrogenesis during embryonic development. In the present study we have performed an immunohistochemical analysis of the distribution of type II collagen during several early stages of embryonic ch...

journal_title：Developmental biology

authors： Kosher RA,Solursh M

更新日期：1989-02-01 00:00:00

abstract：:Spermatogonia are adult germline stem cells that can both self-renew and differentiate into spermatocytes. Little is known about factors necessary for spermatogonial differentiation. We identified a novel germ-cell-specific transcription factor that we named Sohlh1 (testis and ovary expressed basic helix-loop-helix (b...

journal_title：Developmental biology

authors： Ballow D,Meistrich ML,Matzuk M,Rajkovic A

更新日期：2006-06-01 00:00:00