Isolation and characterization of proteolytic fragments of the sea urchin sperm receptor that retain species specificity.

abstract：:Heart valve structures derived from mesenchymal cells of the endocardial cushions (ECs) are composed of highly organized cell lineages and extracellular matrix. Sox9 is a transcription factor required for both early and late stages of cartilage formation that is also expressed in the developing valves of the heart. Th...

journal_title：Developmental biology

authors： Lincoln J,Kist R,Scherer G,Yutzey KE

更新日期：2007-05-01 00:00:00

abstract：:Intestinal tract development is a coordinated process involving signaling among the progenitors and developing cells from all three germ layers. Development of endoderm-derived intestinal epithelium has been shown to depend on epigenetic modifications, but whether that is also the case for intestinal tract cell types ...

journal_title：Developmental biology

authors： Ganz J,Melancon E,Wilson C,Amores A,Batzel P,Strader M,Braasch I,Diba P,Kuhlman JA,Postlethwait JH,Eisen JS

更新日期：2019-11-15 00:00:00

abstract：:The Drosophila abnormal wing discs (awd) gene encodes the subunit of a protein that has nucleoside diphosphate kinase (NDP kinase) activity. Null mutations of the awd gene cause lethality after puparium formation. Larvae homozygous for such mutations have small imaginal discs, lymph glands, and brain lobes. Neither th...

journal_title：Developmental biology

authors： Xu J,Liu LZ,Deng XF,Timmons L,Hersperger E,Steeg PS,Veron M,Shearn A

更新日期：1996-08-01 00:00:00

abstract：:Migration of Anterior Visceral Endoderm (AVE) is a critical symmetry breaking event in the early post-implantation embryo development and is essential for establishing the correct body plan. Despite much effort, cellular and molecular events influencing AVE migration are only partially understood. Here, using time-lap...

journal_title：Developmental biology

authors： Antonica F,Orietti LC,Mort RL,Zernicka-Goetz M

更新日期：2019-06-15 00:00:00

abstract：:NK genes are related pan-metazoan homeobox genes. In the fruitfly, NK genes are clustered and involved in patterning various mesodermal derivatives during embryogenesis. It was therefore suggested that the NK cluster emerged in evolution as an ancestral mesodermal patterning cluster. To test this hypothesis, we cloned...

journal_title：Developmental biology

authors： Saudemont A,Dray N,Hudry B,Le Gouar M,Vervoort M,Balavoine G

更新日期：2008-05-15 00:00:00

abstract：:Malfunctions of motile cilia cause a variety of developmental defects and diseases in humans and animal model organisms. Defects include impaired mucociliary clearance of the airways, sperm immotility, hydrocephalus and organ laterality. Here, we characterize the evolutionary conserved Cfap43 gene by loss-of-function ...

journal_title：Developmental biology

authors： Rachev E,Schuster-Gossler K,Fuhl F,Ott T,Tveriakhina L,Beckers A,Hegermann J,Boldt K,Mai M,Kremmer E,Ueffing M,Blum M,Gossler A

更新日期：2020-03-15 00:00:00

abstract：:One function of the Wingless signaling pathway is to determine the naked, cuticle cell fate choice in the trunk epidermis of Drosophila larvae. The zinc finger protein Teashirt binds to the transactivator domain of Armadillo to modulate Wingless signaling output in the embryonic trunk and contributes to the naked cell...

journal_title：Developmental biology

authors： Angelats C,Gallet A,Thérond P,Fasano L,Kerridge S

更新日期：2002-01-01 00:00:00

abstract：:We report the patterns of migration of Sertoli cells plated on specific substrata, and the influences of testicular peritubular cells on these processes. Data presented indicate that while peritubular cells readily spread when explanted onto Type I collagen, Sertoli cells do not. A delay of 4 to 6 days occurs after Se...

journal_title：Developmental biology

authors： Tung PS,Fritz IB

更新日期：1986-01-01 00:00:00

abstract：:Interleukin-6 is a member of a class of hormone-like molecules termed cytokines. The actions of IL-6 are highly pleiotropic. In adults IL-6 functions as a major mediator of inflammatory responses as well as inducing the synthesis of acute phase proteins by the liver following infection or injury. Based on in vitro and...

journal_title：Developmental biology

authors： Lee FD

更新日期：1992-06-01 00:00:00

abstract：:Lens growth involves the proliferation of epithelial cells, followed by their migration to the equator region and differentiation into secondary fiber cells. It is widely accepted that fibroblast growth factor (FGF) signaling is required for the differentiation of lens epithelial cells into crystallin-rich fibers, but...

journal_title：Developmental biology

authors： Song X,Sato Y,Felemban A,Ito A,Hossain M,Ochiai H,Yamamoto T,Sekiguchi K,Tanaka H,Ohta K

更新日期：2012-08-01 00:00:00

abstract：:During epithelial development cells become polarized along their apical-basal axis and some epithelia also exhibit polarity in the plane of the tissue. Mutations in the gene encoding a Drosophila Pak family serine/threonine kinase, dPak, disrupt the follicular epithelium that covers developing egg chambers during ooge...

journal_title：Developmental biology

authors： Conder R,Yu H,Zahedi B,Harden N

更新日期：2007-05-15 00:00:00

abstract：:Prophase-arrested oocytes of Ruditapes philippinarum are triggered to undergo germinal vesicle breakdown under the influence of the neurohormone serotonin (5HT) and then arrest in metaphase 1. Our data show that these oocytes possess a single class of original 5HT receptors. Their binding parameters have been determin...

journal_title：Developmental biology

authors： Gobet I,Durocher Y,Leclerc C,Moreau M,Guerrier P

更新日期：1994-08-01 00:00:00

abstract：:In the Drosophila ventral nerve cord, the three pairs of Capability neuropeptide-expressing Va neurons are exclusively found in the second, third and fourth abdominal segments (A2-A4). To address the underlying mechanisms behind such segment-specific cell specification, we followed the developmental specification of t...

journal_title：Developmental biology

authors： Suska A,Miguel-Aliaga I,Thor S

更新日期：2011-05-01 00:00:00

abstract：:A polarity in gap junctional permeability normally exists in 32-cell stage Xenopus embryos, in that dorsal cells are relatively more coupled than ventral cells, as measured by transfer of Lucifer yellow dye. The current study extends our analysis of whether gap junctional permeability at this stage can be modulated by...

journal_title：Developmental biology

authors： Olson DJ,Moon RT

更新日期：1992-05-01 00:00:00

abstract：:The development of the action potential and responses to neurotransmitters have been described for a population of embryonic spinal neurons developing in vivo. A comparable pattern is seen for spinal neurons developing in dissociated cell culture. The impulse appears very early in this developmental sequence, and the ...

journal_title：Developmental biology

authors： Bixby JL,Spitzer NC

更新日期：1984-11-01 00:00:00

abstract：:Choriogenesis (eggshell formation) within the silkmoth Antheraea polyphemus proceeds in parallel for the two major subpopulations of follicle cells, diverging only during the very late period when aeropyle crown surface structures form in one region but not in the other. Correlated with their appearance is the synthes...

journal_title：Developmental biology

authors： Regier JC,Cole C,Leclerc RF

更新日期：1993-11-01 00:00:00

abstract：:The zebrafish fin is an excellent system to study the mechanisms of dermal bone patterning. Fin rays are segmented structures that form successive bifurcations both during ontogenesis and regeneration. Previous studies showed that sonic hedgehog (shha) may regulate regenerative bone patterning based on its expression ...

journal_title：Developmental biology

authors： Zhang J,Jeradi S,Strähle U,Akimenko MA

更新日期：2012-05-15 00:00:00

abstract：:Hox genes are thought to participate in patterning the anteroposterior (a-p) axis during vertebrate embryogenesis. In this investigation, the spatial expression of six Hoxb genes was analyzed in early embryos of Xenopus laevis by in situ hybridization. Hoxb gene expression was first detected in late gastrulae/early ne...

journal_title：Developmental biology

authors： Godsave S,Dekker EJ,Holling T,Pannese M,Boncinelli E,Durston A

更新日期：1994-12-01 00:00:00

abstract：:During mammalian spermiogenesis transitional proteins and protamines replace histones on the DNA as the chromatin condenses. While previous studies suggested that histone genes are inactive postmeiotically, we have shown both by steady-state RNA analysis and nuclear run-off transcription assays that histone 2b (H2b) t...

journal_title：Developmental biology

authors： Moss SB,Challoner PB,Groudine M

更新日期：1989-05-01 00:00:00

abstract：:The Egr family of zinc-finger transcription factors, consisting of Egr1, Egr2, Egr3, and Egr4, are involved in cellular growth and differentiation. Adult Egr3-deficient mice are ataxic and lack muscle spindle proprioceptors that normally develop at the sites of Ia afferent-myotube contacts during embryogenesis. To res...

journal_title：Developmental biology

authors： Tourtellotte WG,Keller-Peck C,Milbrandt J,Kucera J

更新日期：2001-04-15 00:00:00

abstract：:Cerebellum development involves the coordinated production of multiple neuronal cell types. The cerebellar primordium contains two germinative zones, the rhombic lip (RL) and the ventricular zone (VZ), which generate different types of glutamatergic and GABAergic neurons, respectively. What regulates the specification...

journal_title：Developmental biology

authors： Fernandes M,Antoine M,Hébert JM

更新日期：2012-05-01 00:00:00

abstract：:In the ascidian Ciona intestinalis, oral siphon amputation activates adult stem cell niches in the branchial sac to divide and dispatch migratory progenitor cells to a regeneration blastema at the site of injury. This study shows that progenitor cells derived from branchial sac stem cell niches have roles in homeostas...

journal_title：Developmental biology

authors： Jeffery WR

更新日期：2019-04-15 00:00:00

abstract：:Embryonic 4- to 15-day-old quail ciliary ganglia (CG) were grafted into the neural crest migration pathway of 2-day-old chick embryos at the adrenomedullary level of the neural axis. This back-transplantation results in dispersion of cells of the implanted ganglion, their migration in the host embryo, and subsequent p...

journal_title：Developmental biology

authors： Dupin E

更新日期：1984-10-01 00:00:00

abstract：:Using sea urchin embryos, we demonstrate that the MEK/MAPK/ERK cascade is essential for the proper progression of the cell cycle. Activation of a limited fraction of MAPK/ERK is required between S-phase and M-phase. Neither DNA replication nor CDK1 activation are impacted by the inhibition of this small active MAPK/ER...

journal_title：Developmental biology

authors： Mulner-Lorillon O,Chassé H,Morales J,Bellé R,Cormier P

更新日期：2017-01-15 00:00:00

abstract：:Immunological approaches were used to characterize an antigen that is present within the cortical granules of mouse oocytes and eggs. Immunoelectron microscopy shows a specific localization of the antigen to the cortical granules in the cortex of mouse oocytes and eggs. Following in vitro fertilization, the antigen is...

journal_title：Developmental biology

authors： Pierce KE,Siebert MC,Kopf GS,Schultz RM,Calarco PG

更新日期：1990-10-01 00:00:00

abstract：:We examined the structure, expression, and possible functions of a nanos homologue during gametogenesis and blastogenesis in the colonial ascidian Botryllus primigenus. An approximately 1.3-kb-long cDNA was cloned; it was termed BpNos since the deduced amino acid sequence (288 aa) contained 2 Nanos-like CCHC zinc fing...

journal_title：Developmental biology

authors： Sunanaga T,Satoh M,Kawamura K

更新日期：2008-12-01 00:00:00

abstract：:Limb buds in the limbless chick begin to form normally but fail to form an AER and ultimately degenerate. Wnt7a and LMX-1, which are restricted to the dorsal half of a normal limb bud, are expressed throughout the ectoderm and mesenchyme of the mutant buds, respectively. Engrailed-1, normally expressed in ventral limb...

journal_title：Developmental biology

authors： Noramly S,Pisenti J,Abbott U,Morgan B

更新日期：1996-11-01 00:00:00

abstract：:The homeobox gene sine oculis (so) is required for the development of the entire visual system in Drosophila, which includes the compound eyes, the ocelli, the optic lobe of the brain and the Bolwig's organ. During ocelli development, so expression labels, together with eyes absent (eya), the emergence of the ocellar ...

journal_title：Developmental biology

authors： Blanco J,Pauli T,Seimiya M,Udolph G,Gehring WJ

更新日期：2010-08-15 00:00:00

abstract：:GATA4, a transcription factor expressed in the proximal small intestine but not in the distal ileum, maintains proximal-distal distinctions by multiple processes involving gene repression, gene activation, and cell fate determination. Friend of GATA (FOG) is an evolutionarily conserved family of cofactors whose member...

journal_title：Developmental biology

authors： Beuling E,Bosse T,aan de Kerk DJ,Piaseckyj CM,Fujiwara Y,Katz SG,Orkin SH,Grand RJ,Krasinski SD

更新日期：2008-10-01 00:00:00

abstract：:The scalloped and vestigial genes are both required for the formation of the Drosophila wing, and recent studies have indicated that they can function as a heterodimeric complex to regulate the expression of downstream target genes. We have analyzed the consequences of complete loss of scalloped function, ectopic expr...

journal_title：Developmental biology

authors： Liu X,Grammont M,Irvine KD

更新日期：2000-12-15 00:00:00