Abstract：
PURPOSE:To investigate the possible association between ibuprofen use and dermatologic superinfections among children with recent varicella infection. METHODS:A retrospective cohort study of children in Harvard Pilgrim Health Care, a health maintenance organization in New England, was conducted. Outcomes and exposures of interest were identified from automated medical and pharmacy records. Exposure was defined by dispensing of ibuprofen before varicella to avoid potential confounding by indication. RESULTS:Between July 1, 1990 and September 30, 1994, 89 superinfections developed among 7,013 cases of varicella. The 30-day risk of superinfection was 7.2/10(3) cases (95% CI = 5.8-8.8/10(3) cases). Four of 169 children dispensed ibuprofen within 180 days of varicella developed superinfection. Relative to children without prior use, children with ibuprofen dispensed in the month prior to varicella were 3.1 times more likely to be diagnosed with a superinfection (95% CI = 0.1-19.7; P-value: 0.31). Restriction of outcomes to superinfections treated with systemic antibiotics increased the odds ratio to 5.1 (95% CI = 0.1-32.5; P-value: 0.22). CONCLUSIONS:The results of this study are consistent with a broad range of effects including no association and suggest that further study is needed.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Choo PW,Donahue JG,Platt Rdoi
10.1016/s1047-2797(97)00040-9subject
Has Abstractpub_date
1997-10-01 00:00:00pages
440-5issue
7eissn
1047-2797issn
1873-2585pii
S1047-2797(97)00040-9journal_volume
7pub_type
杂志文章abstract：PURPOSE:The purpose of this study was to describe time trends in response rates in case-control studies of cancer and identify study design factors that influence response rate. METHODS:We reviewed 370 case-control studies of cancer published in 12 journals during indicator years in each of the last four decades. We e...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.04.001
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:Although much value has been placed on type I error event probabilities in clinical trials, interpretive difficulties often arise that are directly related to clinical trial complexity. Deviations of the trial execution from its protocol, the presence of multiple treatment arms, and the inclusion of multiple en...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/s1047-2797(98)00003-9
更新日期：1998-08-01 00:00:00
abstract：PURPOSE:Birth weight (BW) is associated with risk of cardiovascular (CV) disease. The findings from studies examined the association of BW with metabolic markers of CV risk were inconsistent and controversial. We examined the association of BW with insulin resistance and blood lipids using repeated measures up to mid-a...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.07.013
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To investigate the leukemia risk in a group of benzene exposed workers. METHODS:We conducted a retrospective cohort mortality study on 311 men who worked between January 1, 1951 and December 31, 1968 in a Caprolactam plant in the Netherlands. In the production of Caprolactam (the Nylon 6 monomer) pure benzene ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2004.03.007
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:We aimed to investigate the prevalence and prognostic impact of tumor mesenchymal epithelial transition factor (MET) expression in stage IV gastric cancers in a real-world clinical setting because existing evidence is sparse. METHODS:The study included archived cancer specimens from 103 stage IV gastric cancer...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.05.002
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:To determine whether bladder cancer is associated with exposure to perfluorooctane sulfonate (PFOS) in an occupational cohort. METHODS:Incidence of bladder cancer was ascertained by postal questionnaire to all living current and former employees of the facility (N = 1895) and death certificates for deceased wo...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2007.01.036
更新日期：2007-06-01 00:00:00
abstract：:The evidence that treatment of hypertension prevents stroke is incontrovertible. Several observations, however, suggest that improvements in the prevalence of antihypertensive treatment cannot explain all of the recent decline in stroke mortality. Changes in nutritional patterns may explain some of the observed declin...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(93)90119-o
更新日期：1993-09-01 00:00:00
abstract：PURPOSE:Much cross-sectional work reports an association between neighborhood disadvantage and adverse birth outcomes. Limitations of this work include that mothers with pre-existing unmeasured morbidity may "select" into, or out of, certain neighborhoods. This selection issue remains a key rival explanation for work c...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2019.05.005
更新日期：2019-08-01 00:00:00
abstract：PURPOSE:To examine whether the survival benefit of exercise is modified by obesity. METHODS:In the Northern Manhattan Study, we collected baseline sociodemographics and cardiovascular disease risk factors. The primary exposure was leisure-time physical activity (LTPA) and the outcomes were total, vascular, and nonvasc...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.04.001
更新日期：2015-07-01 00:00:00
abstract：PURPOSE:We estimated female and male incident AIDS diagnosis rates (IARs) among people who inject drugs (PWID) in U.S. metropolitan statistical areas (MSAs) over time to assess whether declines in IARs varied by sex after combination antiretroviral therapy (cART) dissemination. METHODS:We compared IARs and 95% confide...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.01.006
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:The Black Women's Health Study (BWHS) was designed to investigate determinants of health and disease in US black women. More than 64,000 women are enrolled in the BWHS cohort. This study assessed the relative validity of the 68-item food frequency questionnaire (FFQ) used in the BWHS baseline questionnaire. ME...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(02)00253-3
更新日期：2003-02-01 00:00:00
abstract：PURPOSE:To test the association between income inequality and elderly self-rated health and to propose a pathway to explain the relationship. METHODS:We analyzed a sample of 2143 older individuals (60 years of age and over) from 49 distritos of the Municipality of São Paulo, Brazil. Bayesian multilevel logistic models...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2012.09.009
更新日期：2012-12-01 00:00:00
abstract：:Mexican Americans have a high prevalence of diabetes relative to non-Hispanic whites, but paradoxically experience a lower prevalence of myocardial infarction and lower cardiovascular mortality (at least in men). To determine whether Mexican Americans might be more resistant to the atherogenic effects of diabetes than...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(92)90043-p
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To estimate the risk of blood exposure to non-intact skin in U.S. paramedics; to estimate risk ratios for selected management practices. METHODS:A mail survey was conducted among a national sample of licensed paramedics in the United States in 2002-2003. RESULTS:The adjusted response rate was 55% (N = 2,664)....
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2009.08.006
更新日期：2009-12-01 00:00:00
abstract：PURPOSE:Evidence suggests education is an important life course determinant of health, but few studies examine differential returns to education by sociodemographic subgroup. METHODS:Using National Longitudinal Survey of Youth 1979 (n = 6158) cohort data, we evaluate education attained by age 25 years and physical hea...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.08.014
更新日期：2018-11-01 00:00:00
abstract：:The Expanded Programme on Immunization (EPI) of the World Health Organization developed a cluster survey design for the rapid assessment of children's vaccination coverage in developing countries. Because of its simplicity and familiarity, the EPI methodology has been used for additional purposes, including the detect...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)90086-8
更新日期：1994-07-01 00:00:00
abstract：PURPOSE:Medications can have unintended effects. High medication use populations may benefit from increased regimen oversight. Limited knowledge exists concerning racial and regional polypharmacy variation. We estimated total medication distributions (excluding supplements) of American black and white adults and assess...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.01.018
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To elucidate the influence of individual socioeconomic status on smoking in Japanese adults. METHODS:Using a nationally representative sample (20,206 men and 21,093 women aged 18 to 54 years), the relation between smoking and socioeconomic characteristics was analyzed by sex and age group (18 to 24, 25 to 39, ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2004.09.003
更新日期：2005-05-01 00:00:00
abstract：:PURPOSE: Geographic Information Systems (GIS) are useful tools for identifying populations with potential exposure to environmental contaminants. Using a GIS, features of the local environment around an individual's home, work, or school can be described. We present two examples illustrating methods and issues in iden...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00152-6
更新日期：2000-10-01 00:00:00
abstract：PURPOSE:We compared overall survival and influencing factors between Asian-American women as a whole and by subgroup with white women with cervical cancer. METHODS:Cervical cancer data were from the Surveillance, Epidemiology, and End Results registry; socioeconomic information was from the Area Health Resource File. ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.10.004
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:To identify, map, and synthesize the individual-level key associations and modes of exposure for hepatitis C virus (HCV) infection in the Middle East and North Africa (MENA), the most affected region by HCV. METHODS:Source of data was the MENA HCV Epidemiology Synthesis Project database, populated through syst...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.03.007
更新日期：2018-07-01 00:00:00
abstract：:We take a critical look at the meaning behind the number 87% given to 25-year-old Sophie, a BRCA1 and BRCA2 carrier. Sophie has been told she has an 87% chance of getting breast cancer. She is contemplating a preventive double mastectomy after genetic counseling and her physician's advice. Some 92% of British general ...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/j.annepidem.2017.09.005
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:Observational studies in Western settings show moderate alcohol use associated with better cognitive function, but they are vulnerable to contextual bias. Evidence from non-Western settings may be useful to verify causality. We examined such association in southern China where alcohol use is low. METHODS:We us...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2010.06.005
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:Our purpose was to investigate the complex relationship between a range of lifetime abuse experiences with current physical health and health behaviors. METHODS:Between October 1998 and May 1999, interviews were conducted with 557 ethnically diverse women seen at two urban primary care centers. Seven forms of ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(01)00243-5
更新日期：2002-02-01 00:00:00
abstract：PURPOSE:Undiagnosed diabetes disproportionately affects medically underserved groups. It is unknown whether being an immigrant confers additional risk for undiagnosed diabetes. The purpose of this study was to examine independent associations of immigrant status and race/ethnicity with the prevalence of diagnosed and u...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2020.07.009
更新日期：2020-11-01 00:00:00
abstract：:Injuries are the leading cause of death for females 1 to 34 years old, and a major source of preventable morbidity and mortality in middle-aged and elderly women. In the United States, 43,000 women die from injuries and approximately 1 million women are hospitalized for injuries annually. The leading causes of injury ...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/1047-2797(94)90059-0
更新日期：1994-03-01 00:00:00
abstract：:PURPOSE: High mortality rates of cervical cancer among black women have been observed for several decades in the Southeast. The purpose of this study is to assess the factors associated with this geographic and racial enigma, and to see if incidence is consistent with mortality.METHODS: Using the Savannah River Region...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00102-2
更新日期：2000-10-01 00:00:00
abstract：:Many organizations in the United States recommend mammography screening at 1- to 2-year intervals for those 40 to 49 years old. In most areas of Canada and Europe, screening mammography is not recommended for women 40 to 49 years old. These differences have arisen over interpretation of data from the Health Insurance ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)90053-1
更新日期：1994-03-01 00:00:00
abstract：:The association between premature menopause and low back pain was examined among 5325 women surveyed in the second National Health and Nutrition Examination survey. Nearly 49% of the women were postmenopausal. In a multiple logistic regression model that included age, postmenopausal women were approximately twice as l...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)90077-9
更新日期：1994-09-01 00:00:00
abstract：PURPOSE:To evaluate whether existing data and evidence support a causal link between maternal Zika virus (ZIKV) infection and newborn microcephaly. METHODS:I quantified and compared the prevalence of all and severe microcephaly in Brazil, during and before 2015-2016, to assess whether an outbreak has occurred, used ti...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/j.annepidem.2017.11.010
更新日期：2018-02-01 00:00:00
