Reactivation of herpes simplex virus type 1 in cells of latently infected mouse trigeminal ganglia cultured in serum-free medium.

Abstract:

:Herpes simplex virus type 1 (HSV-1) was reactivated more rapidly in cells of latently infected mouse trigeminal ganglia which were cultured in serum-free medium (after 3.7 days of cultivation) than in those cultured in serum-containing Dulbecco's modified Eagle's medium (after 8.5 days of cultivation). The concentration of calcium ion (Ca2+) in the medium affected HSV-1 reactivation in ganglionic cultures, and 0.9 mM was the optimum concentration for the reactivation. Reactivation was delayed significantly in ganglia put into culture 4 months or more after infection compared with those cultured 1 month after infection.

journal_name

Microbiol Immunol

authors

Kimura S

doi

10.1111/j.1348-0421.1996.tb03332.x

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

243-6

issue

3

eissn

0385-5600

issn

1348-0421

journal_volume

40

pub_type

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