Diagnostic value of serum concentrations of high-mobility group-box protein 1 and soluble hemoglobin scavenger receptor in brucellosis.

abstract：:There are two types of carboxypeptidases present in human blood, carboxypeptidase N (CPN) and arginine carboxypeptidase (CPR). CPR is generated during coagulation from a precursor (proCPR) which can be converted to the active form by trypsin in vitro. Since it is difficult to distinguish the two types of carboxypeptid...

journal_title：Microbiology and immunology

authors： Guo X,Morioka A,Kaneko Y,Okada N,Obata K,Nomura T,Campbell W,Okada H

更新日期：1999-01-01 00:00:00

abstract：:Salmonella enterica serovar Typhi and serovar Paratyphi A with reduced susceptibility to fluoroquinolones (MICs of ciprofloxacin, 0.25 to 2 microg/ml) have a mutation at codon either Ser-83 or Asp-87 of gyrA gene. A screening method by PCR-restriction fragment length polymorphism (PCR-RFLP) was designed to screen the ...

journal_title：Microbiology and immunology

authors： Hirose K,Tamura K,Watanabe H

更新日期：2003-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) non-structural protein 5A (NS5A) is a multifunctional protein that is involved in the HCV life cycle and pathogenesis. In this study, a host protein(s) interacting with NS5A by tandem affinity purification were searched for with the aim of elucidating the role of NS5A. An NS5A-interacting prote...

journal_title：Microbiology and immunology

authors： Chen M,Gan X,Yoshino K,Kitakawa M,Shoji I,Deng L,Hotta H

更新日期：2016-06-01 00:00:00

abstract：:Previously we reported that mice infected recurrently with live Fusobacterim nucleatum (Fn) synthesize a significant amount of NO between 12 hr and 24 hr after the Fn injection. We now investigated whether the NO has the capability of killing Fn, a gram-negative rod periodontal pathogen. The mice were divided into thr...

journal_title：Microbiology and immunology

authors： Kato C,Mikami M,Suzuki A,Saito K

更新日期：2003-01-01 00:00:00

abstract：:For the simple and rapid detection/identification of major pathogenic fungal species such as Candida albicans, C. tropicalis, C. parapsilosis, C. glabrata and Aspergillus fumigatus, common primers for these species and specific primers for each species, designed on the basis on the genomic nucleotide sequences of the ...

journal_title：Microbiology and immunology

authors： Kanbe T,Arishima T,Horii T,Kikuchi A

更新日期：2003-01-01 00:00:00

abstract：:A chemotaxonomic study was carried out on 31 strains of non-O1 Vibrio cholerae bio-serogroup Hakata, isolated in Japan, which possesses the Inaba antigen C of O1 V. cholerae. On the basis of the compositional sugar pattern of the polysaccharide portion of their lipopolysaccharides, the 23 strains isolated from the env...

journal_title：Microbiology and immunology

authors： Kondo S,Iguchi T,Haishima Y,Isshiki Y,Hisatsune K

更新日期：1989-01-01 00:00:00

abstract：:The fermentation-inhibition (FI) test for Mycoplasma pneumoniae was improved by using a combination of guinea pig complement and gamma globulin-depleted horse serum in place of unheated whole horse serum employed in the conventional assay system. As the test antigen for the new FI assay system, M. pneumoniae filtrated...

journal_title：Microbiology and immunology

authors： Okazaki N,Akema R,Takizawa K

更新日期：1991-01-01 00:00:00

abstract：:Biofilm formation can cause refractory urinary tract infections (UTIs) in dogs; however, minimum biofilm eradication concentrations (MBECs) of veterinary drugs against canine uropathogens remain to be investigated. In this study, the MBECs of orbifloxacin (OBFX), trimethoprim-sulfamethoxazole (TMS) and amoxicillin/cla...

journal_title：Microbiology and immunology

authors： Shimizu T,Harada K

更新日期：2017-01-01 00:00:00

abstract：:CD4+ cytotoxic T lymphocytes (CTL) clones, YT-4 and YT-9, specific for Toxoplasma gondii (T. gondii)-infected melanoma SK-MEL 28 (P36), were generated from the peripheral blood lymphocytes (PBL) of a patient with chronic toxoplasmosis. These CTL clones were shown to secrete significant amounts of interleukin 6 (IL-6) ...

journal_title：Microbiology and immunology

authors： Yang TH,Aosai F,Norose K,Ueda M,Yano A

更新日期：1996-01-01 00:00:00

abstract：:CD4(+) T cells play critical roles in protection against the blood stage of malarial infection; however, their uncontrolled activation can be harmful to the host. In this study, in which rodent models of Plasmodium parasites were used, the expression of inhibitory receptors on activated CD4(+) T cells and their cytoki...

journal_title：Microbiology and immunology

authors： Doe HT,Kimura D,Miyakoda M,Kimura K,Akbari M,Yui K

更新日期：2016-02-01 00:00:00

abstract：:During Helicobacter pylori infection, T cell response is critical in the development of active gastritis and in protective immunity against infection. We studied gastric inflammation and T cell response in H. pylori-challenged mice following an intraperitoneal immunization, using whole H. pylori lysate (HpAg) in the a...

journal_title：Microbiology and immunology

authors： Watanabe K,Murakami K,Maeda K,Fujioka T,Nasu M,Nishizono A

更新日期：2002-01-01 00:00:00

abstract：:The effect of host cell factors on infectivity of human immunodeficiency virus type 1 (HIV-1) was studied by infecting a monoblastoid cell line (U937) or a T-cell line (MOLT-4) with a highly infective single clone of HIV-1 and comparing the infectivity of the produced viruses to different cell lines. Chronically infec...

journal_title：Microbiology and immunology

authors： el-Farrash MA,Masuda T,Kuroda MJ,Harada S

更新日期：1993-01-01 00:00:00

abstract：:The nuclear factor-kappa B (NF-kappaB) plays a critical role in regulating expression of genes responsible for a wide range of cellular processes, including innate and adoptive immune responses, and pathways related to cell survival and proliferation. Based on its property as a transcription factor, NF-kappaB has been...

journal_title：Microbiology and immunology

authors： Isomura I,Morita A

更新日期：2006-01-01 00:00:00

abstract：:Francisella tularensis, which causes tularemia, is widely distributed in the Northern hemisphere. F. tularensis strains isolated in Japan are genetically unique from non-Japanese strains; however, their phenotypic properties have not been well studied. Thus, mice were infected with representative Japanese strains of F...

journal_title：Microbiology and immunology

authors： Hotta A,Fujita O,Uda A,Yamamoto Y,Sharma N,Tanabayashi K,Yamada A,Morikawa S

更新日期：2016-03-01 00:00:00

abstract：:Staphylococcus aureus strains isolated from bovine intramammary infection (mastitis) were tested for adhesion to bovine mammary epithelial cells after growth in milk whey or TSB. Bacteria grown in milk whey adhered more efficiently to mammary gland epithelial cells in vitro than the corresponding homologous bacteria g...

journal_title：Microbiology and immunology

authors： Mamo W,Fröman G

更新日期：1994-01-01 00:00:00

abstract：:IFN gamma production in cultures of spleen cells obtained from mice sensitized with TH69, a live Streptococcus faecalis preparation, was examined to determine how macrophages participate. It was demonstrated that sensitized spleen macrophages participated in enhanced IFN gamma production by T cells at an early stage (...

journal_title：Microbiology and immunology

authors： Yamaguchi T,Kuroda Y,Yokoyama T,Saito M,Ebina T,Hoshino F,Ishida N

更新日期：1984-01-01 00:00:00

abstract：:Four T antigen-positive phenotypic revertants were isolated by negative selection with BUdR from SV40-transformed rat and mouse cells which contain six and two viral genome equivalents per cell, respectively. Karyological analysis indicated that one rat and one mouse revertant had a hyperploid number of chromosomes, w...

journal_title：Microbiology and immunology

authors： Maruyama K,Furuta T,Ueda K,Oda K

更新日期：1982-01-01 00:00:00

abstract：:A leukocidin was isolated and purified from autolysates of Pseudomonas aeruginosa strain 158 by a combination of procedures such as column chromatography on DEAE-Sephadex A-50, gel filtration on Sephadex G-100, and zone electrophoresis on pevikon. The purified preparation showed a single band in each experiment using ...

journal_title：Microbiology and immunology

authors： Hirayama T,Kato I,Matsuda F,Noda M

更新日期：1983-01-01 00:00:00

abstract：:We have previously identified a heterodimer molecule, Z-1, on guinea pig peritoneal macrophages (M phi s) by the newly prepared monoclonal antibody, anti-Z-1, and Z-1 has been assumed to be the complement receptor type three (CR3) in this species. To clarify this assumption, the cell type distribution of the antigen i...

journal_title：Microbiology and immunology

authors： Tamoto K,Nochi H,Tada M,Kakinuma T,Mori Y

更新日期：1993-01-01 00:00:00

abstract：:Although chronic fatigue syndrome (CFS) is known to be the syndrome that begins with an acute flu-like illness that may be due to the exposure to an infectious agent, there has been no convincing evidence on the causative agents. Recently, human T-lymphotropic virus type II (HTLV-II)-like virus has been reported to be...

journal_title：Microbiology and immunology

authors： Honda M,Kitamura K,Nakasone T,Fukushima Y,Matsuda S,Nishioka K,Matsuda J,Hashimoto N,Yamazaki S

更新日期：1993-01-01 00:00:00

abstract：:Interleukin 5 (IL-5), a lymphokine produced by helper T cells, is involved in the regulation of growth and differentiation of B cells and other hematopoietic cells. To elucidate IL-5-mediated intracellular mechanisms, we have established IL-5-dependent and -independent murine early B cell lines, J6 and MJ88-1, respect...

journal_title：Microbiology and immunology

authors： Migita M,Yamaguchi N,Katoh S,Mita S,Matsumoto R,Sonoda E,Tsuchiya H,Matsuda I,Tominaga A,Takatsu K

更新日期：1990-01-01 00:00:00

abstract：:Macrophages (Mphis), but not T cells, infiltrating into the rejection site of either i.p. allografted Meth A (H-2d) fibrosarcoma cells in C57BL/6 (B6) (H-2b) mice or BALB/c (H-2d) skin onto B6 mice are cytotoxic against allografts with H-2d specificity. To determine the mechanisms of specific killing of allografts by ...

journal_title：Microbiology and immunology

authors： Yoshida R,Oku T,Takikawa O,Einaga-Naito K,Yoneda Y,Hirota R,Kubota T

更新日期：2000-01-01 00:00:00

abstract：:We have developed an indirect microhemagglutination test (IMHA) for detecting antibodies to Borrelia burgdorferi using formalin-fixed chicken erythrocytes sensitized with a sonicated extract of the bacteria. The specificity of IMHA for Lyme disease was compared with that of a conventional indirect immunoperoxidase tec...

journal_title：Microbiology and immunology

authors： Fujita H,Sato T,Ohara Y,Homma M

更新日期：1991-01-01 00:00:00

abstract：:Molecular heterogeneity of the extracellular deoxyribonuclease (DNase) in group A streptococci was demonstrated in 42 clinical isolates. Although polyacrylamide gel electrophoretic patterns of the extracellular DNase of all the isolates were heterogeneous, they could be divided into five main patterns with respect to ...

journal_title：Microbiology and immunology

authors： Miyakawa Y,Yamada T,Shitara M,Fukazawa Y

更新日期：1985-01-01 00:00:00

abstract：:Treatment of macrophages with cytochalasin E in combination with a lectin was found to stimulate the generation of superoxide anions (O2-) very efficiently. The macrophages stimulated with concanavalin A, phytohemagglutinin or wheat germ agglutinin released superoxide, but cells pretreated with cytochalasin E release...

journal_title：Microbiology and immunology

authors： Kayashima K,Onoue K,Nakagawara A,Minakami S

更新日期：1980-01-01 00:00:00

abstract：:Us3 is a serine-threonine protein kinase that is encoded by herpes simplex virus 1 (HSV-1). In experimental animal models of HSV infection, peripheral and intracranial inoculations can be used to study viral pathogenicity in peripheral sites (e.g., eyes and vagina) and central nervous systems (CNSs), respectively. In ...

journal_title：Microbiology and immunology

authors： Koyanagi N,Imai T,Arii J,Kato A,Kawaguchi Y

更新日期：2014-01-01 00:00:00

abstract：:Recipient cells migrating into the transplantation site of an allograft recognize histocompatibility antigens on the grafts and are cytotoxic against the grafts. Although the alloreactive immune response is predominantly directed at the major histocompatibility complex (major histocompatibility complex [MHC]; H-2 in m...

journal_title：Microbiology and immunology

authors： Inoue Y,Tashiro-Yamaji J,Hayashi M,Kiyonari H,Shimizu T,Ibata M,Yamana H,Kubota T,Tanigawa N,Yoshida R

更新日期：2011-06-01 00:00:00

abstract：:A mouse monoclonal antibody, LP4D3, was raised against purified Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) fused to glutathione-S-transferase. The antibody detected endogenous and exogenous EBNA-LP in immunoblotting, immunofluorescence and immunoprecipitation assays, and the epitope of the antibody wa...

journal_title：Microbiology and immunology

authors： Shaku F,Matsuda G,Furuya R,Kamagata C,Igarashi M,Tanaka M,Kanamori M,Nishiyama Y,Yamamoto N,Kawaguchi Y

更新日期：2005-01-01 00:00:00

abstract：:Enterovirus 71 (EV71) is the predominant pathogen for severe hand, foot, and mouth disease (HFMD) in children younger than 5 years, and currently no effective drugs are available for EV71. Thus, there is an urgent need to develop new drugs for the control of EV71 infection. In this study, LJ04 was extracted from Lamin...

journal_title：Microbiology and immunology

authors： Li Z,Cui B,Liu X,Wang L,Xian Q,Lu Z,Liu S,Cao Y,Zhao Y

更新日期：2020-03-01 00:00:00

abstract：:Although the RC-HL strain of rabies virus is avirulent in adult mice, the amino acid at position 333 of its G protein is arginine, which is thought to be necessary for virulence in adult mice upon intracerebral inoculation of the virus. This result suggests that besides arginine at position 333, some other positions o...

journal_title：Microbiology and immunology

authors： Ito H,Minamoto N,Watanabe T,Goto H,Rong LT,Sugiyama M,Kinjo T,Mannen K,Mifune K,Konobe T

更新日期：1994-01-01 00:00:00