Abstract:
:Herpes simplex virus (HSV) class-specific antibody responses after primary genital herpes infection were evaluated with an enzyme-linked immunosorbent assay (ELISA) in 16 patients treated with acyclovir (ACV), given orally, and 17 patients treated with adenine arabinoside (Ara-A), given topically. ACV significantly suppressed the levels of IgM, IgA, and IgG. In the ACV-treated patients, IgM and IgG were not detected in 4 of the 16 and in 1 of the 16 patients, respectively. We must take into account this suppressive effect of ACV on antibody responses, especially on the IgM response, when serodiagnosis of HSV infection is made.
journal_name
Microbiol Immunoljournal_title
Microbiology and immunologyauthors
Kawana T,Hashido M,Koizumi Ydoi
10.1111/j.1348-0421.1995.tb03272.xsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
795-9issue
10eissn
0385-5600issn
1348-0421journal_volume
39pub_type
杂志文章abstract::IFN gamma production in cultures of spleen cells obtained from mice sensitized with TH69, a live Streptococcus faecalis preparation, was examined to determine how macrophages participate. It was demonstrated that sensitized spleen macrophages participated in enhanced IFN gamma production by T cells at an early stage (...
journal_title:Microbiology and immunology
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pub_type: 杂志文章
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更新日期:1991-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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更新日期:2007-01-01 00:00:00
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journal_title:Microbiology and immunology
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Microbiology and immunology
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Microbiology and immunology
pub_type: 杂志文章
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