Prevalence of herpes simplex virus type 1- and 2- specific antibodies among the acute, recurrent, and provoked types of female genital herpes.

Abstract:

:Sixty-eight sera from the acute, recurrent, and provoked types of female genital herpes were compared for the seroprevalence of herpes simplex virus (HSV) types 1 and 2 by immunodot assay using HSV glycoprotein G. In the HSV-1-isolated patients, no HSV-2 antibodies were detected, whereas in the HSV-2-isolated patients, HSV-1 seroprevalence was 9% for the acute type, 89% for the provoked type (P < 0.005), and 55% for the recurrent type (P < 0.05). The natural history of female genital herpes and the possible protective role of pre-existing antibodies in preventing the acquisition or clinical manifestation of a subsequent HSV infection are discussed.

journal_name

Microbiol Immunol

authors

Hashido M,Lee FK,Nahmias AJ,Kawana T

doi

10.1111/j.1348-0421.1997.tb01935.x

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

823-7

issue

10

eissn

0385-5600

issn

1348-0421

journal_volume

41

pub_type

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