B cell tolerance: B cells rendered tolerant are present in the immune system in a potentially responsive form.

abstract：:We have previously shown that immunization of mice with plasmid pMEa synthesizing Japanese encephalitis virus (JEV) envelope protein induced anti-JEV humoral and cellular immune responses. We now show that intra-muscular co-administration of mice with pMEa and pGM-CSF, encoding murine granulocyte-macrophage colony-sti...

journal_title：Microbiology and immunology

authors： Bharati K,Appaiahgari MB,Vrati S

更新日期：2005-01-01 00:00:00

abstract：:Triosephosphate isomerase (TPI; EC 5. 3. 1. 1) displayed on the cell surface of Staphylococcus aureus acts as an adhesion molecule that binds to the capsule of Cryptococcus neoformans, a fungal pathogen. This study investigated the function of TPI on the cell surface of S. aureus and its interactions with biological s...

journal_title：Microbiology and immunology

authors： Furuya H,Ikeda R

更新日期：2011-12-01 00:00:00

abstract：:Us3 is a serine-threonine protein kinase that is encoded by herpes simplex virus 1 (HSV-1). In experimental animal models of HSV infection, peripheral and intracranial inoculations can be used to study viral pathogenicity in peripheral sites (e.g., eyes and vagina) and central nervous systems (CNSs), respectively. In ...

journal_title：Microbiology and immunology

authors： Koyanagi N,Imai T,Arii J,Kato A,Kawaguchi Y

更新日期：2014-01-01 00:00:00

abstract：:An R-form lipopolysaccharide (LPS) extracted from Klebsiella strain LEN-111 (O3-:K1-) by the phenol-chloroform-petroleum ether method was compared with that extracted by the phenol-water method in the ability to form a hexagonal assembly. The LPS which was extracted by the phenol-water method and dialyzed against tap ...

journal_title：Microbiology and immunology

authors： Kato N,Ohta M,Kido N,Ito H,Naito S,Kuno T

更新日期：1985-01-01 00:00:00

abstract：:One- and two-dimensional polyacrylamide gel electrophoresis (PAGE) was performed on immunoprecipitates formed between anti-human T-cell xeno-antiserum (ATS) and cell-surface glycoproteins of human lymphocytes, that had been radioiodinated by lactoperoxidase and purified on a Lentil lectin-coupled Sepharose 4B column. ...

journal_title：Microbiology and immunology

authors： Fujimoto J,Ishii Y,Kon S,Matsuura A,Kikuchi K

更新日期：1981-01-01 00:00:00

abstract：:A simple method for the separation and identification of Bacteroides fragilis from other Bacteroides species through the use of oxgall-impregnated filter paper disks is described. As in the antibiotic sensitivity test, filter paper disks containing defined amounts of bile salt were placed on a lawn of bacterial cells ...

journal_title：Microbiology and immunology

authors： Yamazaki E,Sugimoto K,Niwano K,Okada J

更新日期：1982-01-01 00:00:00

abstract：:Blastomycosis, caused by the thermally dimorphic fungus Blastomyces dermatitides, which is endemic to eastern regions of the USA, is commonly misdiagnosed as a viral or bacterial infection and therefore treated improperly. Over the years, many immunodiagnostic assays to aid in the diagnosis of blastomycosis have been ...

journal_title：Microbiology and immunology

authors： Hatch WO,Scalarone GM

更新日期：2013-11-01 00:00:00

abstract：:The effect of dermonecrotic toxin (DNT), fimbrial hemagglutinin (FHA), K-agglutinogen, lipopolysaccharide (LPS), and pertussigen from Bordetella pertussis on the production of IgE and IgG1 antibodies to hen egg albumin (Ea) was investigated in C57BL/6 mice. The IgE antibody contents were determined by passive cutaneou...

journal_title：Microbiology and immunology

authors： Sekiya K

更新日期：1983-01-01 00:00:00

abstract：:The standard products of V(D)J recombination of immunoglobulin and T cell receptor genes are two kinds of DNA junction, a coding joint and a signal joint. TCR delta V-D and D-D signal joints in adult mouse thymocytes were sequenced following PCR amplification. We observed differential nucleotide insertions at the V de...

journal_title：Microbiology and immunology

authors： Kanari Y,Muto M,Yamagishi H

更新日期：2003-01-01 00:00:00

abstract：:Quantitative PCR (qPCR) of human T-cell leukemia virus type 1 (HTLV-1) provirus is used for HTLV-1 testing and for assessment of risk of HTLV-1-related diseases. In this study, a reference material was developed for standardizing HTLV-1 qPCR. Freeze-dried TL-Om1 cells diluted with Jurkat cells were prepared and an ass...

journal_title：Microbiology and immunology

authors： Kuramitsu M,Okuma K,Nakashima M,Sato T,Sasaki D,Hasegawa H,Umeki K,Kubota R,Sasada K,Sobata R,Matsumoto C,Kaneko N,Tezuka K,Matsuoka S,Utsunomiya A,Koh KR,Ogata M,Ishitsuka K,Taki M,Nosaka K,Uchimaru K,Iwanaga M

更新日期：2018-10-01 00:00:00

abstract：:The fermentation-inhibition (FI) test for Mycoplasma pneumoniae was improved by using a combination of guinea pig complement and gamma globulin-depleted horse serum in place of unheated whole horse serum employed in the conventional assay system. As the test antigen for the new FI assay system, M. pneumoniae filtrated...

journal_title：Microbiology and immunology

authors： Okazaki N,Akema R,Takizawa K

更新日期：1991-01-01 00:00:00

abstract：:Macrophages are extremely heterogeneous mononuclear phagocytes widely distributed throughout the body. They play unique roles in each organ where they reside. Among macrophage subsets, red pulp macrophages (RPMs) that localize in the splenic red pulp, are critical for maintenance of blood homeostasis by actively phago...

journal_title：Microbiology and immunology

authors： Kurotaki D,Uede T,Tamura T

更新日期：2015-02-01 00:00:00

abstract：:Salmonella typhimurium strain 9 produces mini-cells during cell proliferation. Mini-cells are viable but cannot proliferate since they do not contain chromosomal DNA. Effects of whole cells and mini-cells of S. typhimurium on the immune responses were investigated, with the following results. Phagocytosis of peritonea...

journal_title：Microbiology and immunology

authors： Kurashige S,Yoshida T,Kodama K,Mitsuhashi S

更新日期：1981-01-01 00:00:00

abstract：:The lack of a suitable animal model is a major obstacle to developing anti-HIV-1 vaccines. We successfully generated an SIVmac/HIV-1 chimeric virus (SHIV) (designated as NM-3rN) that contains the HIV-1 env gene and is infectious to macaque monkeys. Challenging the vaccinated macaque monkeys with NM-3rN, we developed a...

journal_title：Microbiology and immunology

authors： Haga T,Kuwata T,Ui M,Igarashi T,Miyazaki Y,Hayami M

更新日期：1998-01-01 00:00:00

abstract：:Bacteria of Stenotrophomonas maltophilia have been isolated with increasing frequency from the airways of cystic fibrosis (CF) patients, usually following P. aeruginosa infections, but their adherence to human epithelial respiratory cells has never been investigated. In this study, various S. maltophilia strains were ...

journal_title：Microbiology and immunology

authors： De Vidipó LA,De Marques EA,Puchelle E,Plotkowski MC

更新日期：2001-01-01 00:00:00

abstract：:Trehalose 6,6'-dimycolate (TDM), or cord factor, is a crucial stimulus of immune responses during Mycobacterium tuberculosis infection. Although TDM has immuno-stimulatory properties, including adjuvant activity and the ability to induce granuloma formation, the mechanisms underlying these remain unknown. We hypothesi...

journal_title：Microbiology and immunology

authors： Lee WB,Yan JJ,Kang JS,Chung S,Kim LK

更新日期：2017-12-01 00:00:00

abstract：:In order to analyze the host-parasite interactions in experimental trichomoniasis, the growth of Trichomonas foetus in the peritoneal cavity and changes in the peritoneal exudate cells were followed in mice treated with dextran sulfate 500 (DS 500), a known macrophage-toxic agent. Light microscopic observation showed ...

journal_title：Microbiology and immunology

authors： Oka Y,Hayashi H,Ishikawa F,Osaki H

更新日期：1980-01-01 00:00:00

abstract：:JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system, in immunocompromised patients. Because no drugs have been approved for treating PML, many antiviral agents are currently being investigated for this purpose. The inhibitory effe...

journal_title：Microbiology and immunology

authors： Nukuzuma S,Nakamichi K,Kameoka M,Sugiura S,Nukuzuma C,Tasaki T,Takegami T

更新日期：2016-04-01 00:00:00

abstract：:A gene upstream from fimA, the gene encoding fimbrilin, on the chromosome of Porphyromonas gingivalis was sequenced and shown to be the gene encoding an outer membrane protein in this organism based on homology and biochemical analyses. Therefore, the gene (formerly ORF5) was designated pgmA, the P. gingivalis outer m...

journal_title：Microbiology and immunology

authors： Hongo H,Osano E,Ozeki M,Onoe T,Watanabe K,Honda O,Tani H,Nakamura H,Yoshimura F

更新日期：1999-01-01 00:00:00

abstract：:Magnaporthe oryzae chrysovirus 1 strain A (MoCV1-A) is the causal agent of growth repression and attenuated virulence (hypovirulence) of the rice blast fungus, M. oryzae. We have previously reported that heterologous expression of MoCV1-A ORF4 in Saccharomyces cerevisiae results in growth defects, a large central vacu...

journal_title：Microbiology and immunology

authors： Urayama S,Fukuhara T,Moriyama H,Toh-E A,Kawamoto S

更新日期：2014-05-01 00:00:00

abstract：:Of the various virulence mechanisms of the opportunistic pathogen Pseudomonas aeruginosa, the type III secretion system (TTSS) has been characterized as a major factor associated with acute lung injury, bacteremia and mortality. In addition, PcrV, a component protein of the TTSS, has been characterized as a protective...

journal_title：Microbiology and immunology

authors： Yasumoto H,Katoh H,Kinoshita M,Shimizu M,Hamaoka S,Akiyama K,Naito Y,Sawa T

更新日期：2016-02-01 00:00:00

abstract：:Both cluster of differentiation (CD)4(+) and CD8(+) T lymphocytes play key roles in immunity to Brucella, in part because they secrete interferon (IFN)-γ and activate bactericidal functions in macrophages. Therefore, use of markers of macrophage activation may have diagnostic and prognostic significance. High-mobili...

journal_title：Microbiology and immunology

authors： Ayarcı AO,Yılmaz E,Sığırlı D,Budak F,Göral G,Oral HB

更新日期：2013-02-01 00:00:00

abstract：:Influenza A virus (IAV) PA-X is a critical ribonuclease protein involved in host cell shutoff but its role in modulating the host immune response to IAV infection remains to be addressed. In this study, host cellular proteins that directly interact with PA-X were screened to investigate the biological function of PA-X...

journal_title：Microbiology and immunology

authors： Li M,Qi W,Chang Q,Chen R,Zhen D,Liao M,Wen J,Deng Y

更新日期：2020-11-26 00:00:00

abstract：:Cytochalasin B (CB) and cytochalasin D (CD), inhibitors of microfilament function of host cell, were examined for their effects on Staphylococcus aureus Cowan I adherence to and ingestion by several types of the hyperosmolarity-tolerant (HOT) cells obtained from primary culture of mouse kidney. Staphylococcal adherenc...

journal_title：Microbiology and immunology

authors： Murai M,Seki K,Sakurada J,Usui A,Masuda S

更新日期：1993-01-01 00:00:00

abstract：:β-1,3-glucan is a major component of fungal cell walls with various biological activities, including effects on the production of inflammatory mediators in vivo and in vitro. However, few reports have examined its influence on the fungal cell itself. In this study, the influences of β-1,3-glucan on the growth and cell...

journal_title：Microbiology and immunology

authors： Ishibashi K,Kurone Y,Motoi M,Miura NN,Adachi Y,Shirasu Y,Ohno N

更新日期：2010-11-01 00:00:00

abstract：:A mouse monoclonal antibody, LP4D3, was raised against purified Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) fused to glutathione-S-transferase. The antibody detected endogenous and exogenous EBNA-LP in immunoblotting, immunofluorescence and immunoprecipitation assays, and the epitope of the antibody wa...

journal_title：Microbiology and immunology

authors： Shaku F,Matsuda G,Furuya R,Kamagata C,Igarashi M,Tanaka M,Kanamori M,Nishiyama Y,Yamamoto N,Kawaguchi Y

更新日期：2005-01-01 00:00:00

abstract：:Viable but nonculturable (VBNC) Vibrio cholerae non-O1/non-O139, V. parahaemolyticus, enterohemorrhagic Escherichia coli, enterotoxigenic E. coli, enteropathogenic E. coli, Shigella flexneri, and Salmonella enterica were converted to the culturable state by co-culture with selected eukaryotic cells, e.g., HT-29, Caco-...

journal_title：Microbiology and immunology

authors： Senoh M,Ghosh-Banerjee J,Ramamurthy T,Colwell RR,Miyoshi S,Nair GB,Takeda Y

更新日期：2012-05-01 00:00:00

abstract：:To detect neutralization-relevant antibodies against 3 types of poliovirus (PV) without using tissue cultures and live viruses, an enzyme-linked immunosorbent assay (ELISA) based on monoclonal antibody-binding inhibition was evaluated using sera from 80 vaccinated Japanese children and 60 Pakistani poliomyelitis patie...

journal_title：Microbiology and immunology

authors： Hashido M,Horie H,Abe S,Doi Y,Hashizume S,Agboatwalla M,Isomura S,Nishio O,Hagiwara A,Inouye S

更新日期：1999-01-01 00:00:00

abstract：:Biofilm formation is an important phenotype associated with chronic Pseudomonas aeruginosa infections. In the present study, a total of 48 P. aeruginosa strains isolated from clinical specimens were examined for their biofilm-forming ability using a microtiter plate method. The different biofilm-forming abilities were...

journal_title：Microbiology and immunology

authors： Yang W,Shi L,Jia WX,Yin X,Su JY,Kou Y,Yi X,Shinoda S,Miyoshi S

更新日期：2005-01-01 00:00:00

abstract：:Cryptosporidium spp. is a major cause of diarrhea in developing countries, mainly affecting people with compromised immune systems in general and HIV-infected individuals with low CD4 + T-cell counts in particular. This infection is self-limiting in healthy persons; however, it can be severe, progressive and persisten...

journal_title：Microbiology and immunology

authors： Izadi M,Jonaidi-Jafari N,Saburi A,Eyni H,Rezaiemanesh MR,Ranjbar R

更新日期：2012-12-01 00:00:00