Purine metabolic enzymes in lymphocytes. II. Adenosine deaminase and purine nucleoside phosphorylase activities in the immune response.

abstract：:A cytotoxic T lymphocyte (CTL) response to dengue virus-infected target cells is described. Effector cells were generated in an in vitro secondary culture and appeared to be T cells possessing both the Lyt 1.1 and Lyt 2.1 surface antigens. A stronger CTL response was noted with the H-2k haplotype compared to H-2d, and...

journal_title：Microbiology and immunology

authors： Pang T,Devi S,Blanden RV,Lam SK

更新日期：1988-01-01 00:00:00

abstract：:Neonatal toxic shock syndrome-like exanthematous disease (NTED) is a new entity of methicillin-resistant Staphylococcus aureus (MRSA) infection. Most of NTED cases reported previously in the literature were sporadic ones. In the present report, we describe an outbreak of NTED that occurred in a neonatal intensive care...

journal_title：Microbiology and immunology

authors： Nakano M,Miyazawa H,Kawano Y,Kawagishi M,Torii K,Hasegawa T,Iinuma Y,Ohta M

更新日期：2002-01-01 00:00:00

abstract：:Four N-acetylchito-oligosaccharides, from tetra-N-acetylchitotetraose (NACOS-4) to hepta-N-acetylchitoheptaose (NACOS-7), were found to increase the number of peritoneal exudate cells (PEC) in male BALB/c mice after 3 hr intraperitoneal administration of 50 mg/kg of each oligosaccharide. The number of attracted cells,...

journal_title：Microbiology and immunology

authors： Suzuki K,Tokoro A,Okawa Y,Suzuki S,Suzuki M

更新日期：1986-01-01 00:00:00

abstract：:Vpr, one of the accessory molecules of HIV-1, has been demonstrated to arrest the cell cycle at the G2 phase. This Vpr-mediated cell cycle arrest is implicated to have an important role in the viral life cycle. In the present study, we quantitate the extent of Vpr-mediated cell cycle arrest with the use of a bicistron...

journal_title：Microbiology and immunology

authors： Yamaguchi T,Watanabe N,Nakauchi H,Koito A

更新日期：1999-01-01 00:00:00

abstract：:Specific tumor microenvironment signaling might prevent the maturation of dendritic cells (DCs) with tolerogenic and immunosuppressive potential accounting for antigen-specific unresponsiveness in the lymphoid organs and in the periphery. In the present study, dendritic cells treated with LLC lung cancer cell or 4T1 b...

journal_title：Microbiology and immunology

authors： Ma C,Su M,Shen K,Chen J,Ning Y,Qi C

更新日期：2020-01-01 00:00:00

abstract：:A leukocidin was isolated and purified from autolysates of Pseudomonas aeruginosa strain 158 by a combination of procedures such as column chromatography on DEAE-Sephadex A-50, gel filtration on Sephadex G-100, and zone electrophoresis on pevikon. The purified preparation showed a single band in each experiment using ...

journal_title：Microbiology and immunology

authors： Hirayama T,Kato I,Matsuda F,Noda M

更新日期：1983-01-01 00:00:00

abstract：:The effects of LV in two different species, CD-1 mice, without a genetic disposition for diabetes, and BB rats prone to T1D were examined. Male CD-1 mice that had been exposed to LV in utero developed a type 2-like diabetes with increased blood glucose, insulin levels and epididymal fat at the age of 10-15 weeks. Comb...

journal_title：Microbiology and immunology

authors： Holmberg R,Klitz W,Blixt M,Berggren PO,Juntti-Berggren L,Niklasson B

更新日期：2009-10-01 00:00:00

abstract：:Farnesol is well known as a quorum-sensing molecule of Candida albicans. To assess the pathological function of farnesol, its effects on macrophage viability and functions including growth inhibitory activities against C. albicans were examined in vitro. Murine macrophages, when cultured in the presence of 56-112 micr...

journal_title：Microbiology and immunology

authors： Abe S,Tsunashima R,Iijima R,Yamada T,Maruyama N,Hisajima T,Abe Y,Oshima H,Yamazaki M

更新日期：2009-06-01 00:00:00

abstract：:Two gram-negative, catalase-negative, oxidase-positive strains (PAGU 1467T and PAGU 1468) isolated from patients with infective endocarditis were investigated to determine their taxonomic status. 16S rRNA gene sequence analysis indicated that the two strains were members of the Bergeyella-Chryseobacterium-Riemerella b...

journal_title：Microbiology and immunology

authors： Tomida J,Fujiwara N,Naka T,Morita Y,Sawabe E,Tojo N,Kikuchi K,Kawamura Y

更新日期：2019-03-01 00:00:00

abstract：:Measuring the amount of HIV-1 DNA in infected cells is important to estimate the size of the viral reservoir in patients. However, the clinical impact of the intracellular viral DNA level remains unclear. The present study examines the clinical significance of the HIV-1 DNA level in peripheral CD4+ T lymphocytes from ...

journal_title：Microbiology and immunology

authors： Wada K,Nagai H,Hagiwara T,Ibe S,Utsumi M,Kaneda T

更新日期：2004-01-01 00:00:00

abstract：:DNase B is a major nuclease and a possible virulence factor in Streptococcus pyogenes. The allelic diversity of streptococcal DNase B (sdaB) gene was investigated in 83 strains with 14 emm genotypes. Of the 15 alleles identified, 11 alleles carried only synonymous nucleotide substitutions. On the other hand, 4 alleles...

journal_title：Microbiology and immunology

authors： Matsumoto M,Sakae K,Hashikawa S,Torii K,Hasegawa T,Horii T,Endo M,Okuno R,Murayama S,Hirasawa K,Suzuki R,Isobe J,Tanaka D,Katsukawa C,Tamaru A,Tomita M,Ogata K,Ikebe T,Watanabe H,Ohta M,Working Group for Group A S

更新日期：2005-01-01 00:00:00

abstract：:Butanol-extracted water-soluble adjuvant (Bu-WSA) obtained from Bacterionema matruchotii was cultured with peripheral blood mononuclear cells (PBM) in the presence of sub- and/or supra-optimal mitogenic concentrations of concanavalin A (Con A). The addition of Bu-WSA resulted in increased tritiated thymidine incorpora...

journal_title：Microbiology and immunology

authors： Nitta T,Okumura S,Tsushi M,Nakano M

更新日期：1982-01-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) was reactivated more rapidly in cells of latently infected mouse trigeminal ganglia which were cultured in serum-free medium (after 3.7 days of cultivation) than in those cultured in serum-containing Dulbecco's modified Eagle's medium (after 8.5 days of cultivation). The concentrati...

journal_title：Microbiology and immunology

authors： Kimura S

更新日期：1996-01-01 00:00:00

abstract：:The genospecies Borrelia afzelii was isolated from a patient of Lyme disease in Hokkaido, Japan, for the first time, by culturing the minced erythema lesion in BSK II medium. Two analytical methods, rRNA gene restriction fragment length polymorphism (RFLP) and polymerase chain reaction (PCR) using the specific primer ...

journal_title：Microbiology and immunology

authors： Nakao M,Miyamoto K,Fukunaga M,Hashimoto Y,Takahashi H

更新日期：1994-01-01 00:00:00

abstract：:An oral delivery system based on ApxIIA#5-expressed on Saccharomyces cerevisiae was studied for its potential to induce immune responses in mice. Murine bone marrow-derived dendritic cells (DCs) stimulated in vitro with ApxIIA#5-expressed on S. cerevisiae upregulated the expression of maturation and activation markers...

journal_title：Microbiology and immunology

authors： Shin MK,Lee WJ,Jung MH,Cha SB,Shin SW,Yoo A,Kim DH,Yoo HS

更新日期：2013-06-01 00:00:00

abstract：:Virulence of Coxsackie virus B3 (CB3) was compared in mice between strain SK-74 isolated from a patient and strain T-70 isolated from a healthy child as well as between prototype strain Nancy and its mouse-passaged derivative strain PMH. Strain SK-74 showed a high mortality (40-80%), while strain T-70 did not induce d...

journal_title：Microbiology and immunology

authors： Komatsu T,Hashimoto I,Kohara T

更新日期：1983-01-01 00:00:00

abstract：:A possible role of intracellular Ca2+ and participation of calmodulin in cellular metabolism in endotoxin-poisoned mice were investigated. The levels of calcium in liver cytosol and liver mitochondria fractions in poisoned mice were markedly higher 18-48 hr after endotoxin injection than in the control mice. On the ot...

journal_title：Microbiology and immunology

authors： Sakaguchi S,Abe H,Sakaguchi O

更新日期：1984-01-01 00:00:00

abstract：:A total of 207 strains of Bordetella bronchiseptica isolated from pigs in 1978 and 1979 were tested for drug resistance and for the properties of their R plasmids. Apart from intrinsic resistance to spectinomycin, single (sulfadimethoxine), double (sulfadimethoxine and streptomycin), andt riple (sulfadimethoxine, stre...

journal_title：Microbiology and immunology

authors： Shimizu M,Kuninori K,Inoue M,Mitsuhashi S

更新日期：1981-01-01 00:00:00

abstract：:Corilagin and tellimagrandin I are polyphenols isolated from the extract of Arctostaphylos uvaursi and Rosa canina L. (rose red), respectively. We have reported that corilagin and tellimagrandin I remarkably reduced the minimum inhibitory concentration (MIC) of beta-lactams in methicillin-resistant Staphylococcus aure...

journal_title：Microbiology and immunology

authors： Shiota S,Shimizu M,Sugiyama J,Morita Y,Mizushima T,Tsuchiya T

更新日期：2004-01-01 00:00:00

abstract：:This study investigated the mechanisms of resistance of 36 quinolone-resistant Salmonella Typhimurium strains isolated from outpatients with infectious diarrhea in Beijing Tian Tan Hospital between 2013 and 2015. The resistance spectrum of the 36 strains was measured using a broth dilution method. Class 1 integrons ha...

journal_title：Microbiology and immunology

authors： Yuan J,Guo W

更新日期：2017-04-01 00:00:00

abstract：:Experiments were performed to investigate the resistance of the host due to antibody-mediated mechanisms to herpes simplex virus (HSV) infection. Transfer of hyperimmune anti-HSV mouse serum inhibited the development of skin lesions and prolonged the survival of lethally HSV-infected nude mice. Relatively high concent...

journal_title：Microbiology and immunology

authors： Hayashida I,Nagafuchi S,Hayashi Y,Kino Y,Mori R,Oda H,Ohtomo N,Tashiro A

更新日期：1982-01-01 00:00:00

abstract：:We cloned and sequenced two new Verotoxin 2 (VT2) variant genes: one from an Escherichia coli strain from a case of bovine diarrhea and the other from an E. coli strain from a patient with diarrhea. The nucleotide and amino acid sequences of these two genes were highly homologous with, but distinct from those of the V...

journal_title：Microbiology and immunology

authors： Lin Z,Yamasaki S,Kurazono H,Ohmura M,Karasawa T,Inoue T,Sakamoto S,Suganami T,Takeoka T,Taniguchi Y

更新日期：1993-01-01 00:00:00

abstract：:The effect of human normal serum (HNS) on Pseudomonas pseudomallei was determined. It is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. Ancillary experiments to confirm this serum-resistant property of P. pseudomallei were done by examining the effects of growth phase...

journal_title：Microbiology and immunology

authors： Ismail G,Razak N,Mohamed R,Embi N,Omar O

更新日期：1988-01-01 00:00:00

abstract：:Recurrent otitis media are frequently intractable during childhood. It is unclear whether recurrent otitis media is caused by etiological bacteria colonization or by new infections. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis were isolated from the nasopharynx of 7 otitisprone and 2 non-...

journal_title：Microbiology and immunology

authors： Yokota S,Harimaya A,Sato K,Somekawa Y,Himi T,Fujii N

更新日期：2007-01-01 00:00:00

abstract：:An emetic toxin cereulide, produced by Bacillus cereus, causes emetic food poisonings, but a method for quantitative measurement of cereulide has not been well established. A current detection method is a bioassay method using the HEp-2 cell vacuolation test, but it was unable to measure an accurate concentration. We ...

journal_title：Microbiology and immunology

authors： Kawamura-Sato K,Hirama Y,Agata N,Ito H,Torii K,Takeno A,Hasegawa T,Shimomura Y,Ohta M

更新日期：2005-01-01 00:00:00

abstract：:Human immunodeficiency virus type-1 (HIV-1) and human T-cell leukemia virus type-I (HTLV-I) have a similar tropism for target cell types, especially for CD4+ T cells. In this study, we provide evidence that receptors of these two viruses exist independently on the target cell. We established an HTLV-I-producing CD8+ T...

journal_title：Microbiology and immunology

authors： Kannagi M,Kuroda MJ,Maeda Y,Harada S

更新日期：1991-01-01 00:00:00

abstract：:A novel combination of antimicrobial agents (sulfamethoxazole, 40 μg/mL; trimethoprim, 20 μg/mL; amphotericin B, 5 μg/mL; fosfomycin, 400 μg/mL; and 5-fluorouracil, 100 μg/mL) was developed for selective isolation of leptospires from contaminated samples. The growth of 16 microorganisms considered as possible contamin...

journal_title：Microbiology and immunology

authors： Chakraborty A,Miyahara S,Villanueva SY,Saito M,Gloriani NG,Yoshida S

更新日期：2011-07-01 00:00:00

abstract：:We evaluated the efficacy of three SARS vaccine candidates in a murine SARS model utilizing low-virulence Pp and SARS-CoV coinfection. Vaccinated mice were protected from severe respiratory disease in parallel with a low virus titer in the lungs and a high neutralizing antibody titer in the plasma. Importantly, the ad...

journal_title：Microbiology and immunology

authors： Ishii K,Hasegawa H,Nagata N,Ami Y,Fukushi S,Taguchi F,Tsunetsugu-Yokota Y

更新日期：2009-02-01 00:00:00

abstract：:Leptospire lipopolysaccharide (LPS) stimulated the adherence of polymorphonuclear neutrophils (PMNs) to human umbilical vein endothelial cells (HUVEC). Enhanced PMN adherence in response to leptospire LPS can be mediated by platelet-activator-factor (PAF), because a PAF antagonist reduced adherence. Leptospire LPS als...

journal_title：Microbiology and immunology

authors： Isogai E,Hirose K,Kimura K,Hayashi S,Kubota T,Fujii N,Isogai H

更新日期：1997-01-01 00:00:00

abstract：:The amino acid sequence of the principal neutralizing determinant (PND) of 224 cases of human immunodeficiency virus type 1 (HIV-1) was determined and the most frequently occurring sequence was used as a peptide antigen for studying virus-specific antibody responses. In our present study, a linear peptide of the most ...

journal_title：Microbiology and immunology

authors： Bukawa H,Fukushima J,Hamajima K,Kimura M,Tsuji T,Xin KQ,Okuda K

更新日期：1995-01-01 00:00:00