A novel combination of selective agents for isolation of Leptospira species.

abstract：:In recent years, phosphatidylinositol 4-kinase III beta (PI4KB) has emerged as a conserved target of anti-picornavirus compounds. In the present study, PI4KB was identified as the direct target of the plant-derived anti-picornavirus compounds, oxoglaucine and pachypodol (also known as Ro 09-0179). PI4KB was also ident...

journal_title：Microbiology and immunology

authors： Arita M,Philipov S,Galabov AS

更新日期：2015-06-01 00:00:00

abstract：:Both cluster of differentiation (CD)4(+) and CD8(+) T lymphocytes play key roles in immunity to Brucella, in part because they secrete interferon (IFN)-γ and activate bactericidal functions in macrophages. Therefore, use of markers of macrophage activation may have diagnostic and prognostic significance. High-mobili...

journal_title：Microbiology and immunology

authors： Ayarcı AO,Yılmaz E,Sığırlı D,Budak F,Göral G,Oral HB

更新日期：2013-02-01 00:00:00

abstract：:Borrelia duttonii strain 406K, a causative agent of relapsing fever, could not be cultivated in vitro in currently available media for borreliae. We have developed an in vitro cultivation system by using SflEp cell cultures. The average increases of the number of borreliae, when inoculated with 1.0 x 10(5) organisms p...

journal_title：Microbiology and immunology

authors： Konishi H,Morshed MG,Akitomi H,Nakazawa T

更新日期：1993-01-01 00:00:00

abstract：:Streptococcus pyogenes, a group A Streptococcus (GAS), has been recognized as the causative pathogen in patients with severe invasive streptococcal infection with or without necrotizing fasciitis. In recent epidemiological studies, Streptococcus dysgalactiae subsp. equisimilis (SDSE) has been isolated from severe inva...

journal_title：Microbiology and immunology

authors： Watanabe S,Takemoto N,Ogura K,Miyoshi-Akiyama T

更新日期：2016-01-01 00:00:00

abstract：:Phage TP1, induced from Vibrio parahaemolyticus K-20 pilot strain by mitomycin C, exhibited a unique hexagonal head with knob-like projections which covered the whole capsid and a noncontractile tail. The appearance of this phage was very similar to those of phages VP3 and VP6, isolated from seawater. The host range o...

journal_title：Microbiology and immunology

authors： Koga T,Kawata T

更新日期：1991-01-01 00:00:00

abstract：:Histopathological observations of changes at the injection site in mice were made for 20 weeks after a single intramuscular (im) injection of aluminum hydroxide-adsorbed tetanus toxoid (Alum-TT), plain tetanus toxoid (TT), or aluminum adjuvant (Alum alone). Marked injury to muscle fibers and infiltration of neutrophil...

journal_title：Microbiology and immunology

authors： Goto N,Akama K

更新日期：1982-01-01 00:00:00

abstract：:There are many examples of probiotic effects of various lactic bacteria on enteropathogens. In this study, Lactobacillus strains (L. rhamnosus, L. gasseri, L. casei and L. plantarum) were tested in an in vitro model of enterohemorrhagic Escherichia coli (EHEC) infection of a human colon epithelial cell line, C2BBe1. W...

journal_title：Microbiology and immunology

authors： Hirano J,Yoshida T,Sugiyama T,Koide N,Mori I,Yokochi T

更新日期：2003-01-01 00:00:00

abstract：:Manipulation of viral genomes is essential for studying viral gene function and utilizing viruses for therapy. Several techniques for viral genome engineering have been developed. Homologous recombination in virus-infected cells has traditionally been used to edit viral genomes; however, the frequency of the expected ...

journal_title：Microbiology and immunology

authors： Suenaga T,Kohyama M,Hirayasu K,Arase H

更新日期：2014-09-01 00:00:00

abstract：:The function of MHC class II HLA-DR molecules expressed on a human B lymphoid progenitor cell line FL8.2.4.4 (abbreviated as FL4.4) was examined. FL4.4 cells expressed HLA-DR molecules and stimulation of the DR molecules by anti-DR mAb or by superantigen TSST-1 induced strong augmentation of homocytic aggregation and ...

journal_title：Microbiology and immunology

authors： Naitoh K,Ichigi Y,Miyake K,Muraguchi A,Kimoto M

更新日期：1994-01-01 00:00:00

abstract：:Based on the results of a phylogenetic analysis of 16S rRNA and the presence of sphingoglycolipid in cellular lipids of the type strains, transfer of "Rhizomonas" suberifaciens, Blastomonas natatoria and Erythromonas ursincola to the genus Sphingomonas as Sphingomonas suberifaciens (van Bruggen et al 1990) comb. nov.,...

journal_title：Microbiology and immunology

authors： Yabuuchi E,Kosako Y,Naka T,Suzuki S,Yano I

更新日期：1999-01-01 00:00:00

abstract：:Enterovirus 71 (EV71) is the predominant pathogen for severe hand, foot, and mouth disease (HFMD) in children younger than 5 years, and currently no effective drugs are available for EV71. Thus, there is an urgent need to develop new drugs for the control of EV71 infection. In this study, LJ04 was extracted from Lamin...

journal_title：Microbiology and immunology

authors： Li Z,Cui B,Liu X,Wang L,Xian Q,Lu Z,Liu S,Cao Y,Zhao Y

更新日期：2020-03-01 00:00:00

abstract：:Clostridium perfringens KZ1340, previously classified as Clostridium plagarum, is an isolate from Antarctic soil, and was identified as an alpha-, theta-, and kappa-toxin non-producing variant. On Southern hybridization, the variant was found to be defective in the pfoA (theta-toxin) gene, but the plc (alpha-toxin) an...

journal_title：Microbiology and immunology

authors： Shimizu T,Ohtani K,Ba-Thein W,Inui S,Nakamura S,Hayashi H

更新日期：1996-01-01 00:00:00

abstract：:A murine monoclonal antibody recognizing (1-->6)-beta-D-glucopyranosyl laminaritriose (G4) was prepared by immunizing BALB/c mice with G4-bovine serum albumin conjugate and fusing the splenocytes with mouse myeloma cells. The monoclonal antibody (IgM) provoked by the cloned cells showed low reactivity with schizophyll...

journal_title：Microbiology and immunology

authors： Hirata A,Komoda M,Itoh W,Tabata K,Sugawara I

更新日期：1995-01-01 00:00:00

abstract：:Development of accurate methods for predicting progression of tuberculosis (TB) from the latent state is recognized as vitally important in controlling TB, because a majority of cases develop from latent infections. Past TB that has never been treated has a higher risk of progressing than does latent Mycobacterium tub...

journal_title：Microbiology and immunology

authors： Osada-Oka M,Tateishi Y,Hirayama Y,Ozeki Y,Niki M,Kitada S,Maekura R,Tsujimura K,Koide Y,Ohara N,Yamamoto T,Kobayashi K,Matsumoto S

更新日期：2013-01-01 00:00:00

abstract：:Pathogens of the Aspergillus species are frequently seen in deep-seated mycoses. We previously demonstrated that the culture filtrate of Aspergillus fumigatus (CF) has immunosuppressive effects on polymorphonuclear leukocytes (PMNs), which act as the main phagocytes to hyphae of Aspergillus fumigatus (A. fumigatus). B...

journal_title：Microbiology and immunology

authors： Higurashi H,Arai M,Watanabe A,Igari H,Seki N,Kamei K,Kuriyama T

更新日期：2007-01-01 00:00:00

abstract：:Salmonella typhimurium strain 9 produces mini-cells during cell proliferation. Mini-cells are viable but cannot proliferate since they do not contain chromosomal DNA. Effects of whole cells and mini-cells of S. typhimurium on the immune responses were investigated, with the following results. Phagocytosis of peritonea...

journal_title：Microbiology and immunology

authors： Kurashige S,Yoshida T,Kodama K,Mitsuhashi S

更新日期：1981-01-01 00:00:00

abstract：:Rapid western blot (WB) procedure for an abnormal isoform of prion protein (PrP(Sc) ) detection in lymphoid tissues was established and has been applied to the surveillance of fallen stock. In this program, brain and palatal tonsil were examined by WB and three cases of sheep scrapie were detected. While one clinicall...

journal_title：Microbiology and immunology

authors： Shimada K,Hayashi HK,Ookubo Y,Iwamaru Y,Imamura M,Takata M,Schmerr MJ,Shinagawa M,Yokoyama T

更新日期：2005-01-01 00:00:00

abstract：:Magnaporthe oryzae chrysovirus 1 strain A (MoCV1-A) is the causal agent of growth repression and attenuated virulence (hypovirulence) of the rice blast fungus, M. oryzae. We have previously reported that heterologous expression of MoCV1-A ORF4 in Saccharomyces cerevisiae results in growth defects, a large central vacu...

journal_title：Microbiology and immunology

authors： Urayama S,Fukuhara T,Moriyama H,Toh-E A,Kawamoto S

更新日期：2014-05-01 00:00:00

abstract：:The attachment of Mycoplasma pulmonis m53 organisms to mouse and rat synovial cells was examined by using the organisms and the synovial cells treated in various ways. M. pulmonis treated with trypsin attached to the synovial cells, but the organisms treated with pronase, formaldehyde, glutaraldehyde, or heat did not....

journal_title：Microbiology and immunology

authors： Araake M,Yayoshi M,Yoshioka M

更新日期：1985-01-01 00:00:00

abstract：:Numerical analysis of 211 strains of rapidly growing, nonphotochromogenic mycobacteria was carried out by using 116 characters. New species reported after 1981 and not yet compared with known species by numerical classification were included. At the level of 90% of the matching coefficient, the following species could...

journal_title：Microbiology and immunology

authors： Tsukamura M,Ichiyama S

更新日期：1986-01-01 00:00:00

abstract：:Autoantibodies to myeloperoxidase (MPO) are a subset of anti-neutrophil cytoplasmic antibody (ANCA, MPO-ANCA) detected in the sera of some patients with primary systemic vasculitis. The titer of MPO-ANCA does not always reflect disease activity and this inconsistency may be attributable to differences in epitopic spec...

journal_title：Microbiology and immunology

authors： Suzuki K,Kobayashi S,Yamazaki K,Gondo M,Tomizawa K,Arimura Y,Nakabayashi K,Ozaki S,Yoshida M,Yoshida T,Tsusaka N,Muso E,Okazaki T,Hashimoto H

更新日期：2007-01-01 00:00:00

abstract：:Intracellular localization of the wild-type (Spv+), the phoP-constitutively expressed strain (PhoPc), and the spv-deleted strain (Spv-) of Salmonella typhimurium was examined by the use of confocal laser scanning microscopy analysis of immunostained sections of mouse spleens after oral or subcutaneous inoculation. Onl...

journal_title：Microbiology and immunology

authors： Matsui H,Eguchi M,Kikuchi Y

更新日期：2001-01-01 00:00:00

abstract：:Japanese encephalitis virus (JEV) core protein is detected not only in the cytoplasm but also in the nucleoli of infected cells. We previously showed that a mutant JEV lacking the nucleolar localization of the core protein impaired viral replication in mammalian cells. In this study, we identified a nucleolar phosphop...

journal_title：Microbiology and immunology

authors： Tsuda Y,Mori Y,Abe T,Yamashita T,Okamoto T,Ichimura T,Moriishi K,Matsuura Y

更新日期：2006-01-01 00:00:00

abstract：:The 16S toxin was purified from a Clostridium botulinum type D strain 1873 (D-1873). Furthermore, the entire nucleotide sequences of the genes coding for the 16S toxin were determined. It became clear that the purified D-1873 16S toxin consists of neurotoxin, nontoxic nonhemagglutinin (NTNH), and hemagglutinin (HA), a...

journal_title：Microbiology and immunology

authors： Nakajima H,Inoue K,Ikeda T,Fujinaga Y,Sunagawa H,Takeshi K,Ohyama T,Watanabe T,Inoue K,Oguma K

更新日期：1998-01-01 00:00:00

abstract：:We examined the mechanisms of fluconazole resistance in a fluconazole-resistant Candida albicans isolate from a Japanese patient with chronic mucocutaneous candidiasis. It was demonstrated that the highly resistant phenotype of this strain was associated with combined mechanisms of the energy-dependent reduced intrace...

journal_title：Microbiology and immunology

authors： Kamai Y,Maebashi K,Kudoh M,Makimura K,Naka W,Uchida K,Yamaguchi H

更新日期：2004-01-01 00:00:00

abstract：:L forms of Salmonella typhimurium LT2 conferred strong protection to a lethal challenge with its parental bacterium on innately hypersusceptible C3H/HeJ mice, and its minimal protective dose was approximately 150 L-forming units. Although L-form S. typhimurium was avirulent for C3H/HeJ mice, it multiplied slowly in bo...

journal_title：Microbiology and immunology

authors： Nishikawa F,Kita E,Yamada H,Nakano A,Kashiba S

更新日期：1994-01-01 00:00:00

abstract：:Serum samples were collected from 938 pigs of 24 farms in Hokkaido, Kagoshima, and Okinawa prefectures in Japan in 2001-2005. Enzyme-linked immunosorbent assay (ELISA) was used for the detection of antibodies to LipL32 antigen which is common to Leptospira interrogans. Samples positive in ELISA were then investigated ...

journal_title：Microbiology and immunology

authors： Naito M,Sakoda Y,Kamikawa T,Nitta Y,Hirose K,Sakashita M,Kurokawa S,Kida H

更新日期：2007-01-01 00:00:00

abstract：:To clarify the humoral immunity in herpes simplex virus (HSV) infection, HSV-specific IgM, IgA and IgG subclass antibody responses were studied in patients with genital herpes: 17 primary, 13 recurrent and 6 nonprimary first episode. A total of 181 serum samples serially collected from the patients, 5 per patient unti...

journal_title：Microbiology and immunology

authors： Hashido M,Kawana T

更新日期：1997-01-01 00:00:00

abstract：:In this review, we have emphasized: 1) bacterial lipopolysaccharide (LPS) involvement in IgA responses to orally administered thymic-dependent (TD) antigens; 2) characterization of Peyer's patch (PP) lymphoreticular cells; and 3) gastrointestinal immunization with gram negative pathogens and anti-LPS immunity to infec...

journal_title：Microbiology and immunology

authors： McGhee JR,Michalek SM,Kiyono H,Eldridge JH,Colwell DE,Williamson SI,Wannemuehler MJ,Jirillo E,Mosteller LM,Spalding DM

更新日期：1984-01-01 00:00:00

abstract：:Many pathogens colonize host tissues by binding to the extracellular matrix via their cell surface adhesion molecules, which are called MSCRAMMs (microbial surface components recognizing adhesive matrix molecules). Staphylococcus aureus expresses several of these adhesion molecules, some of which bind to fibronectin. ...

journal_title：Microbiology and immunology

authors： Shinji H,Kamada M,Seki K,Tajima A,Iwase T,Masuda S

更新日期：2007-01-01 00:00:00