Nucleolar protein B23 interacts with Japanese encephalitis virus core protein and participates in viral replication.

Abstract:

:Japanese encephalitis virus (JEV) core protein is detected not only in the cytoplasm but also in the nucleoli of infected cells. We previously showed that a mutant JEV lacking the nucleolar localization of the core protein impaired viral replication in mammalian cells. In this study, we identified a nucleolar phosphoprotein B23 as a protein binding with the core protein of JEV but not with that of dengue virus. The region binding with JEV core protein was mapped to amino acid residues 38 to 77 of B23. Upon JEV infection, some fraction of B23 was translocated from the nucleoli to the cytoplasm, and cytoplasmic B23 was colocalized with the core protein of wild-type JEV but not with that of the mutant JEV. Furthermore, overexpression of dominant negatives of B23 reduced JEV replication. These results suggest that B23 plays an important role in the intracellular localization of the core protein and replication of JEV.

journal_name

Microbiol Immunol

authors

Tsuda Y,Mori Y,Abe T,Yamashita T,Okamoto T,Ichimura T,Moriishi K,Matsuura Y

doi

10.1111/j.1348-0421.2006.tb03789.x

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

225-34

issue

3

eissn

0385-5600

issn

1348-0421

pii

JST.JSTAGE/mandi/50.225

journal_volume

50

pub_type

杂志文章
  • Infection of J774A.1 with different Mycobacterium species induces differential immune and miRNA-related responses.

    abstract::Macrophages act as a reservoir for Mycobacterium tuberculosis, producing latent infection in approximately 90% of infected people. In this study, J774A.1 mouse macrophage cell line response and microRNA (miRNA) expression during infection with the most relevant mycobacterial strains for humans (M. tuberculosis, M. bov...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12380

    authors: Elizabeth MC,Hernández de la Cruz ON,Mauricio CA

    更新日期:2016-05-01 00:00:00

  • Evaluation of an enzyme-linked immunosorbent assay based on binding inhibition for type-specific quantification of poliovirus neutralization-relevant antibodies.

    abstract::To detect neutralization-relevant antibodies against 3 types of poliovirus (PV) without using tissue cultures and live viruses, an enzyme-linked immunosorbent assay (ELISA) based on monoclonal antibody-binding inhibition was evaluated using sera from 80 vaccinated Japanese children and 60 Pakistani poliomyelitis patie...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1999.tb02375.x

    authors: Hashido M,Horie H,Abe S,Doi Y,Hashizume S,Agboatwalla M,Isomura S,Nishio O,Hagiwara A,Inouye S

    更新日期:1999-01-01 00:00:00

  • Capsule of Streptococcus pyogenes is essential for delayed death of mice in a model of streptococcal toxic shock syndrome.

    abstract::We have previously reported a mouse model of severe group A streptococcal infection (Microbiol. Immunol. 45: 777-786, 2001). When we injected Streptococcus pyogenes strains intramuscularly, the mice suffered from acute phase of infection for a few days but recovered from the illness and gained body weight. These mice,...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2006.tb03777.x

    authors: Iida K,Seki M,Saito M,Kawamura Y,Kajiwara H,Yoshida S

    更新日期:2006-01-01 00:00:00

  • Analysis of the structural gene encoding a hemolysin in Vibrio mimicus.

    abstract::An environmental isolate of V. mimicus, strain E-33, has been reported to produce and secrete a hemolysin of 63 kDa. The hemolysin is enterotoxic in test animals. The nucleotide sequence of the structural gene of the hemolysin was determined. We found a 2,232 bp open reading frame, which codes a peptide of 744 amino a...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1997.tb01183.x

    authors: Rahman MM,Miyoshi S,Tomochika K,Wakae H,Shinoda S

    更新日期:1997-01-01 00:00:00

  • Experimental infection of specific-pathogen-free mice with enterohemorrhagic Escherichia coli O157:H7.

    abstract::By subcutaneous inoculation of 10(8) CFU of enterohemorrhagic E. coli O157:H7, specific-pathogen-free mice revealed most of the symptoms and histological changes observed in patients. The histological changes in intestine were mainly seen in the distal parts of small intestine and the cecum. Vacuolation of villi in th...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1991.tb01582.x

    authors: Lai XH,Xu JG,Liu BY

    更新日期:1991-01-01 00:00:00

  • Macrophage migration inhibitory factor (MIF) produced by a human T cell hybridoma clone.

    abstract::A human T cell hybridoma clone, F5, producing high levels of macrophage migration inhibitory factor (MIF) was established by the emetine-actinomycin D selection method. This clone produced two species of MIF which were separated on a Phenyl Sepharose column. We purified MIF-2 (the more hydrophobic species of the two) ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1991.tb01552.x

    authors: Hirose S,Ooki S,Higuchi M,Osawa T

    更新日期:1991-01-01 00:00:00

  • Interaction of triosephosphate isomerase from Staphylococcus aureus with plasminogen.

    abstract::Triosephosphate isomerase (TPI; EC 5. 3. 1. 1) displayed on the cell surface of Staphylococcus aureus acts as an adhesion molecule that binds to the capsule of Cryptococcus neoformans, a fungal pathogen. This study investigated the function of TPI on the cell surface of S. aureus and its interactions with biological s...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2011.00392.x

    authors: Furuya H,Ikeda R

    更新日期:2011-12-01 00:00:00

  • Leukocyte integrin-dependent and antibody-independent cytotoxicity of macrophage against allografts.

    abstract::Macrophages (Mphis), but not T cells, infiltrating into the rejection site of either i.p. allografted Meth A (H-2d) fibrosarcoma cells in C57BL/6 (B6) (H-2b) mice or BALB/c (H-2d) skin onto B6 mice are cytotoxic against allografts with H-2d specificity. To determine the mechanisms of specific killing of allografts by ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2000.tb01246.x

    authors: Yoshida R,Oku T,Takikawa O,Einaga-Naito K,Yoneda Y,Hirota R,Kubota T

    更新日期:2000-01-01 00:00:00

  • Detection of DNA of causative agent of spotted fever group rickettsiosis in Japan from the patient's blood sample by polymerase chain reaction.

    abstract::The polymerase chain reaction (PCR) was applied for the etiological diagnosis of spotted fever group (SFG) rickettsiosis in Japan. Nucleotide primers derived from the 17-kDa antigen gene of Rickettsia rickettsii primed a rickettsia-specific 246-base-pair product for all of the Katayama, Abe, Misaka and Kojima strains,...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1994.tb01837.x

    authors: Tange Y,Matsumoto M,Okada T,Hasegawa H,Kobayashi Y

    更新日期:1994-01-01 00:00:00

  • A unique mutation of glycoprotein gene of the attenuated RC-HL strain of rabies virus, a seed virus used for production of animal vaccine in Japan.

    abstract::Although the RC-HL strain of rabies virus is avirulent in adult mice, the amino acid at position 333 of its G protein is arginine, which is thought to be necessary for virulence in adult mice upon intracerebral inoculation of the virus. This result suggests that besides arginine at position 333, some other positions o...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1994.tb01812.x

    authors: Ito H,Minamoto N,Watanabe T,Goto H,Rong LT,Sugiyama M,Kinjo T,Mannen K,Mifune K,Konobe T

    更新日期:1994-01-01 00:00:00

  • The influence of β-glucan on the growth and cell wall architecture of Aspergillus spp.

    abstract::β-1,3-glucan is a major component of fungal cell walls with various biological activities, including effects on the production of inflammatory mediators in vivo and in vitro. However, few reports have examined its influence on the fungal cell itself. In this study, the influences of β-1,3-glucan on the growth and cell...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2010.00264.x

    authors: Ishibashi K,Kurone Y,Motoi M,Miura NN,Adachi Y,Shirasu Y,Ohno N

    更新日期:2010-11-01 00:00:00

  • Peptidase activity of dipeptidyl aminopeptidase IV produced by Porphyromonas gingivalis is important but not sufficient for virulence.

    abstract::Porphyromonas gingivalis is a pathogen associated with adult periodontitis, which is a chronic inflammatory disease characterized by breakdown of the periodontal tissue. Dipeptidyl aminopeptidase IV (DPPIV) produced by P. gingivalis has been considered to be a potential virulence factor based on the finding that the v...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2003.tb03443.x

    authors: Kumagai Y,Yajima A,Konishi K

    更新日期:2003-01-01 00:00:00

  • Molecular subtyping for Escherichia coli O157: H7 isolated in Taiwan.

    abstract::Enterohaemorrhagic Escherichia coli O157: H7 is an important pathogen these days. Outbreaks of its infection have been reported all over the world, in Australia, Canada, Japan, the United States, south Africa, and various countries in Europe. In the summer of 2001, the first clinical infection by E. coli O157: H7 was ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2005.tb03649.x

    authors: Tsai TY,Luo WC,Wu FT,Pan TM

    更新日期:2005-01-01 00:00:00

  • Characterization of an enterotoxin produced by Vibrio cholerae O139.

    abstract::A cholera-like enterotoxin was purified from Vibrio cholerae O139 strain AI-1841 isolated from a diarrheal patient in Bangladesh. Its characteristics were compared with that of cholera toxins (CTs) of classical strain 569B and El Tor strain KT25. Al-1841 produced as much toxin as O1 strains. The toxins were indistingu...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1995.tb02174.x

    authors: Nakashima K,Eguchi Y,Nakasone N

    更新日期:1995-01-01 00:00:00

  • Molecular composition of the 16S toxin produced by a Clostridium botulinum type D strain, 1873.

    abstract::The 16S toxin was purified from a Clostridium botulinum type D strain 1873 (D-1873). Furthermore, the entire nucleotide sequences of the genes coding for the 16S toxin were determined. It became clear that the purified D-1873 16S toxin consists of neurotoxin, nontoxic nonhemagglutinin (NTNH), and hemagglutinin (HA), a...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1998.tb02330.x

    authors: Nakajima H,Inoue K,Ikeda T,Fujinaga Y,Sunagawa H,Takeshi K,Ohyama T,Watanabe T,Inoue K,Oguma K

    更新日期:1998-01-01 00:00:00

  • Immune responses against allogeneic and syngeneic tumors in aged C57BL/6 mice.

    abstract::Aged C57BL/6 (B6) mice could reject allogeneic BALB/c RL male 1 tumor as efficiently as young B6 mice. However, in vitro analysis showed impaired generation of cytotoxic T cell response in aged B6 mice against allogeneic tumor. The reaction could be augmented by the addition of recombinant interleukin-2 (rIL-2). Enzym...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2002.tb02728.x

    authors: Win S,Uenaka A,Nakayama E

    更新日期:2002-01-01 00:00:00

  • Increased multiplication of dengue virus in mouse peritoneal macrophage cultures by treatment with extracts of Ascaris-Parascaris parasites.

    abstract::Methylcellulose-elicited peritoneal macrophages from BALB/c mice were cultivated in vitro and inoculated with dengue virus (DV). At intervals thereafter portions of the culture fluids were taken and titrated for viral infectivity. Extracts from Ascaris suum and Parascaris equorum, either crude or Sephadex G-100 fracti...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1985.tb00832.x

    authors: Wiharta AS,Hotta H,Hotta S,Matsumura T,Sujudi,Tsuji M

    更新日期:1985-01-01 00:00:00

  • Prevalence of colonization factor antigens (CFAs) and adherence to HeLa cells in enterotoxigenic Escherichia coli isolated from feces of children in São Paulo.

    abstract::Fifty-eight enterotoxigenic Escherichia coli (ETEC) strains, isolated from children with and without diarrhea in São Paulo, were examined for the presence of colonization factor antigens (CFAs) and their ability to adhere to HeLa cells. Antisera to CFA/I, the coli surface (CS) antigens CS1CS3, CS2CS3, and CS2 of CFA/I...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1994.tb01844.x

    authors: Guth BE,Aguiar EG,Griffin PM,Ramos SR,Gomes TA

    更新日期:1994-01-01 00:00:00

  • Complete genome sequence and characterization of virulence genes in Lancefield group C Streptococcus dysgalactiae isolated from farmed amberjack (Seriola dumerili).

    abstract::Lancefield group C Streptococcus dysgalactiae causes infections in farmed fish. Here, the genome of S. dysgalactiae strain kdys0611, isolated from farmed amberjack (Seriola dumerili) was sequenced. The complete genome sequence of kdys0611 consists of a single chromosome and five plasmids. The chromosome is 2,142,780 b...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12716

    authors: Nishiki I,Yoshida T,Fujiwara A

    更新日期:2019-07-01 00:00:00

  • Differential expression pattern of ISG15 in different tissue explants and cells induced by various interferons.

    abstract::Interferon stimulated gene 15 (ISG15), an ubiquitin cross-reactive protein, can conjugate to target proteins. Unlike ubiquitination, protein modification by ISG15 does not target protein for degradation, but enhances the cellular response to interferon (IFN), which plays a key role in antiviral responses. In this stud...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2012.00419.x

    authors: Yang L,Zhang LY,Wang C,Wang B,Wang XM,Zeng SM

    更新日期:2012-03-01 00:00:00

  • Studies on the sulfite reduction test for clostridia.

    abstract::Peptone-yeast extract (PY) medium containing 0.035% ferric ammonium citrate as an indicator, 0.05% sulfite as a substrate, 0.05% cysteine as a reducer and 0.5% glucose was found to be suitable for observing the sulfite reduction test. The effect of added cysteine on the test was suppressed by the addition of glucose. ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1980.tb02830.x

    authors: Kawabata N

    更新日期:1980-01-01 00:00:00

  • Difference in response of NK cell activity in newborns and adult to IL-2, IL-12 and IL-15.

    abstract::The killing activity of cord blood mononuclear cells (cMNC) against cytomegalovirus (CMV)-uninfected and -infected fibroblasts was comparable to that of adult peripheral blood mononuclear cells (aPBMC). The killing activity of cMNC against K562 cells was significantly lower compared with that of aPBMC. Treatment of cM...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1999.tb02387.x

    authors: Hoshina T,Kida K,Ito M

    更新日期:1999-01-01 00:00:00

  • Cell surface of a tetrads-forming mutant of Micrococcus luteus: chemical treatment of the cells and teichuronic acids on the surface.

    abstract::Tetrads-forming mutant MT cells of Micrococcus luteus, both treated with chemical reagents and non-treated, were observed with a scanning electron microscope (SEM). The agglutinability of the cells with antiserum containing anti-teichuronic acid antibody was examined. The binding of protein A-gold particles to the cel...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1990.tb00992.x

    authors: Monodane T,Tokunaga M,Torii M

    更新日期:1990-01-01 00:00:00

  • A highly effective method for removing suspended poliovirus from water using a positively-charged carbon felt electrode.

    abstract::We developed an effective system to eliminate poliovirus from modified tap water using a positively-charged carbon felt electrode. The zeta potential of polioviruses was measured using laser microscopic electrophoresis. Poliovirus adsorption to the electrode was examined by indirect immunofluorescence. The tissue cult...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2004.tb03557.x

    authors: Kondo Y,Morita Y,Yamada A,Kimura H

    更新日期:2004-01-01 00:00:00

  • Hepatitis C virus NS5B RNA replicase specifically binds ribosomes.

    abstract::Hepatitis C virus (HCV) non-structural protein 5B (NS5B) is an RNA replicase. We expressed full-length NS5B (591 amino acid residues) in Escherichia coli as a fusion protein with maltose binding protein (MBP-NS5B). MBP-NS5B was recovered in the soluble fraction after centrifugation at 40,000 x g and affinity-purified ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2000.tb02532.x

    authors: Tanaka T,Sugiyama K,Ikeda M,Naganuma A,Nozaki A,Saito M,Shimotohno K,Kato N

    更新日期:2000-01-01 00:00:00

  • Plasma levels of unactivated thrombin activatable fibrinolysis inhibitor (TAFI) are down-regulated in young adult women: analysis of a normal Japanese population.

    abstract::Thrombin-activatable fibrinolysis inhibitor (TAFI) is an anaphylatoxin-inactivating enzyme generated by proteolytic cleavage of its zymogen, and is the same enzyme as that first designated by our group as procarboxypeptidase R (proCPR). TAFI in plasma is presumed to influence vascular disease in its role as a fibrinol...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2007.tb03939.x

    authors: Akatsu H,Ishiguro M,Ogawa N,Kanesaka T,Okada N,Yamamoto T,Campbell W,Okada H

    更新日期:2007-01-01 00:00:00

  • Molecular epidemiology of Japanese encephalitis virus in Okinawa.

    abstract::In order to elucidate the molecular characteristics of Japanese encephalitis (JE) virus in Okinawa, 23 strains of JE virus isolated in a 25-year span were sequenced for the 240 nucleotides of the C-preM junction region and 111 nucleotides of the E gene region and compared with those of reference strains isolated in ma...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1996.tb01150.x

    authors: Ma SP,Arakaki S,Makino Y,Fukunaga T

    更新日期:1996-01-01 00:00:00

  • Spodiobacter cordis gen. nov. sp. nov., a member of the family Flavobacteriaceae isolated from patients with infective endocarditis.

    abstract::Two gram-negative, catalase-negative, oxidase-positive strains (PAGU 1467T and PAGU 1468) isolated from patients with infective endocarditis were investigated to determine their taxonomic status. 16S rRNA gene sequence analysis indicated that the two strains were members of the Bergeyella-Chryseobacterium-Riemerella b...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12673

    authors: Tomida J,Fujiwara N,Naka T,Morita Y,Sawabe E,Tojo N,Kikuchi K,Kawamura Y

    更新日期:2019-03-01 00:00:00

  • Proliferation of functional human natural killer cells with anti-HIV-1 activity in NOD/SCID/Jak3(null) mice.

    abstract::Natural killer cells, a critical component of the innate immune system, eradicate both virus-infected cells and tumor cells through cytotoxicity and secretion of cytokines. Human NK cell research has largely been based on in vitro studies because of the lack of appropriate animal models. In this study, a selective pro...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12355

    authors: Hattori S,Matsuda K,Kariya R,Harada H,Okada S

    更新日期:2016-02-01 00:00:00

  • Proposal of a new scheme for the serological typing of Enterococcus faecalis strains.

    abstract::No systematic study on serotyping of Enterococcus faecalis has been reported since 1964 when M.E. Sharpe conducted serotyping of group D streptococcus in U.K. So, we attempted to re-evaluate serotyping of E. faecalis. For this purpose, we received 42 Sharpe's strains and first examined for their biochemical characteri...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1992.tb02070.x

    authors: Maekawa S,Yoshioka M,Kumamoto Y

    更新日期:1992-01-01 00:00:00