Severe invasive streptococcal infection by Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis.

abstract：:To establish an in vitro method of predicting in vivo efficacy of antifungal drugs against Candida albicans and Aspergillus fumigatus, the antifungal activities of fluconazole, itraconazole, and amphotericin B were determined in mouse serum. The minimum inhibitory concentration (MIC) of each drug was measured using mo...

journal_title：Microbiology and immunology

authors： Maki K,Watabe E,Iguchi Y,Nakamura H,Tomishima M,Ohki H,Yamada A,Matsumoto S,Ikeda F,Tawara S,Mutoh S

更新日期：2006-01-01 00:00:00

abstract：:Site-specific recombinase is widely applied for the regulation of gene expression because its regulatory action is strict and efficient. However, each system can mediate regulation of only one gene at a time. Here, we demonstrate efficient "sequential" gene regulation using Cre-and FLP-expressing recombinant adenoviru...

journal_title：Microbiology and immunology

authors： Kondo S,Takahashi Y,Shiozawa S,Ichise H,Yoshida N,Kanegae Y,Saito I

更新日期：2006-01-01 00:00:00

abstract：:We have previously reported a mouse model of severe group A streptococcal infection (Microbiol. Immunol. 45: 777-786, 2001). When we injected Streptococcus pyogenes strains intramuscularly, the mice suffered from acute phase of infection for a few days but recovered from the illness and gained body weight. These mice,...

journal_title：Microbiology and immunology

authors： Iida K,Seki M,Saito M,Kawamura Y,Kajiwara H,Yoshida S

更新日期：2006-01-01 00:00:00

abstract：:Zymographic analysis was performed to know the bacteriolytic enzyme profiles of 4% SDS extracts of oral streptococci, Streptococcus mutans, S. sobrinus, S. sanguis, S. mitis and S. salivarius. We investigated the five strains in each species and found that the profile was very similar among strains of the same species...

journal_title：Microbiology and immunology

authors： Yoshimura G,Komatsuzawa H,Kajimura J,Fujiwara T,Ohara M,Kozai K,Sugai M

更新日期：2004-01-01 00:00:00

abstract：:We compared the intracellular survival and growth of Legionella pneumophila Philadelphia-1 in peritoneal macrophages obtained from A/J, C57BL/6, and X-linked chronic granulomatous disease (CGD) mice produced from C57BL/6 strain. The initial killing was observed in A/J and C57BL/6 macrophages at 2, 4 and 6 hr after in ...

journal_title：Microbiology and immunology

authors： Saito M,Kajiwara H,Miyamoto H,Yoshida S

更新日期：2001-01-01 00:00:00

abstract：:The aim of this study was to evaluate the association between antibodies against cytomegalovirus (CMV) glycoprotein B (gB) and acute rejection after transplantation. Seventy-seven consecutive renal transplant recipients in a D + /R+ setting were studied. Biopsy-proven rejection occurred in 35% of the recipients. Among...

journal_title：Microbiology and immunology

authors： Ishibashi K,Tokumoto T,Shirakawa H,Oguro T,Yanagida T,Takahashi N,Nomiya M,Haga N,Aikawa K,Tanabe K,Inoue N,Kojima Y,Suzutani T

更新日期：2014-01-01 00:00:00

abstract：:A novel combination of antimicrobial agents (sulfamethoxazole, 40 μg/mL; trimethoprim, 20 μg/mL; amphotericin B, 5 μg/mL; fosfomycin, 400 μg/mL; and 5-fluorouracil, 100 μg/mL) was developed for selective isolation of leptospires from contaminated samples. The growth of 16 microorganisms considered as possible contamin...

journal_title：Microbiology and immunology

authors： Chakraborty A,Miyahara S,Villanueva SY,Saito M,Gloriani NG,Yoshida S

更新日期：2011-07-01 00:00:00

abstract：:Experiments were performed to investigate the resistance of the host due to antibody-mediated mechanisms to herpes simplex virus (HSV) infection. Transfer of hyperimmune anti-HSV mouse serum inhibited the development of skin lesions and prolonged the survival of lethally HSV-infected nude mice. Relatively high concent...

journal_title：Microbiology and immunology

authors： Hayashida I,Nagafuchi S,Hayashi Y,Kino Y,Mori R,Oda H,Ohtomo N,Tashiro A

更新日期：1982-01-01 00:00:00

abstract：:Capture enzyme-linked immunosorbent assays (ELISAs) were developed to detect immunoglobulin G and M antibodies to group A streptococcal (GAS) antigens, streptolysin O, streptokinase, and group A carbohydrate. The sensitivities and the specificities of the IgM capture ELISAs to each GAS antigen were high enough to dist...

journal_title：Microbiology and immunology

authors： Hayashi S,Yokota K,Takizawa Y,Tomizawa I,Nejime T,Oguma K

更新日期：1993-01-01 00:00:00

abstract：:The effect of dermonecrotic toxin (DNT), fimbrial hemagglutinin (FHA), K-agglutinogen, lipopolysaccharide (LPS), and pertussigen from Bordetella pertussis on the production of IgE and IgG1 antibodies to hen egg albumin (Ea) was investigated in C57BL/6 mice. The IgE antibody contents were determined by passive cutaneou...

journal_title：Microbiology and immunology

authors： Sekiya K

更新日期：1983-01-01 00:00:00

abstract：:A reversed passive latex agglutination (RPLA) assay for detecting Clostridium difficile toxin A is presented. Purified monoclonal antibody (mAb 37B5) was used for latex sensitization. The culture supernatants of 93 strains of C. difficile were tested by RPLA assay and the results compared with those of a commercially ...

journal_title：Microbiology and immunology

authors： Toma C,Nakamura S,Kamiya S,Nakasone N,Iwanaga M

更新日期：1999-01-01 00:00:00

abstract：:Sodium vanadate enhanced Newcastle disease virus (NDV)-induced cell fusion in L cells, and there was a direct correlation between the degree of cell fusion and the dose of vanadate added. When anti-F protein of NDV monospecific antiserum was added to the culture fluid of L cells infected with NDV, the enhancement of c...

journal_title：Microbiology and immunology

authors： Yamamoto F,Fujioka H,Iinuma M,Takano M,Maeno K,Nagai Y,Ito Y

更新日期：1984-01-01 00:00:00

abstract：:Staphylococcal exfoliative toxin A (ETA) had a splitting effect at the granular layer of skin in humans and neonatal mice, but not in rabbits, guinea pigs, golden hamsters, or rats. Besides its splitting effect, ETA could stimulate productions of neutralizing antibody to ETA in rabbits, rats and B10D2 mice, but not in...

journal_title：Microbiology and immunology

authors： Machida K,Sakurai S,Kondo I,Ikawa S

更新日期：1988-01-01 00:00:00

abstract：:Human adenoviruses (HAdVs) are an important cause of acute gastroenteritis in children. However, few studies on the epidemiology or types of HAdVs associated with acute gastroenteritis have been conducted in Korea. Therefore, in the present study, the incidence of HAdV in 2064 stool samples from Korean children hospit...

journal_title：Microbiology and immunology

authors： Lee JI,Lee GC,Chung JY,Han TH,Lee YK,Kim MS,Lee CH

更新日期：2012-08-01 00:00:00

abstract：:Clostridium perfringens KZ1340, previously classified as Clostridium plagarum, is an isolate from Antarctic soil, and was identified as an alpha-, theta-, and kappa-toxin non-producing variant. On Southern hybridization, the variant was found to be defective in the pfoA (theta-toxin) gene, but the plc (alpha-toxin) an...

journal_title：Microbiology and immunology

authors： Shimizu T,Ohtani K,Ba-Thein W,Inui S,Nakamura S,Hayashi H

更新日期：1996-01-01 00:00:00

abstract：:The production from murine resident peritoneal macrophages (M phi) of a soluble factor, which was capable of enhancing the antigen-presenting (AP) function of dendritic cells (DC), was examined. The supernatants of peritoneal M phi (M phi sup) were prepared by culturing peritoneal M phi with particles, i.e., zymosan A...

journal_title：Microbiology and immunology

authors： Miyazaki H,Ito A,Osawa T

更新日期：1988-01-01 00:00:00

abstract：:The nucleic acid fraction from cells of 6 species of bacterium and 2 kinds of vertebrate, calf and salmon, was extracted and purified by the same procedures as described previously. When the spleen cells from BALB/c mice were incubated with the nucleic acid fraction from either of the bacteria, natural killer (NK) act...

journal_title：Microbiology and immunology

authors： Yamamoto S,Yamamoto T,Shimada S,Kuramoto E,Yano O,Kataoka T,Tokunaga T

更新日期：1992-01-01 00:00:00

abstract：:Four N-acetylchito-oligosaccharides, from tetra-N-acetylchitotetraose (NACOS-4) to hepta-N-acetylchitoheptaose (NACOS-7), were found to increase the number of peritoneal exudate cells (PEC) in male BALB/c mice after 3 hr intraperitoneal administration of 50 mg/kg of each oligosaccharide. The number of attracted cells,...

journal_title：Microbiology and immunology

authors： Suzuki K,Tokoro A,Okawa Y,Suzuki S,Suzuki M

更新日期：1986-01-01 00:00:00

abstract：:Based on the results of a phylogenetic analysis of 16S rRNA and the presence of sphingoglycolipid in cellular lipids of the type strains, transfer of "Rhizomonas" suberifaciens, Blastomonas natatoria and Erythromonas ursincola to the genus Sphingomonas as Sphingomonas suberifaciens (van Bruggen et al 1990) comb. nov.,...

journal_title：Microbiology and immunology

authors： Yabuuchi E,Kosako Y,Naka T,Suzuki S,Yano I

更新日期：1999-01-01 00:00:00

abstract：:The incidence of infection by Actinobacillus actinomycetemcomitans, one of the important pathogens in human periodontal diseases, has been reported to be associated with racial background and genetic factors. We attempted to determine the genetic regulation of immune responses to A. actinomycetemcomitans fimbriae, an ...

journal_title：Microbiology and immunology

authors： Honma K,Ishii N,Kato T,Ishihara K,Okuda K,Okuda K

更新日期：1997-01-01 00:00:00

abstract：:In recent years, phosphatidylinositol 4-kinase III beta (PI4KB) has emerged as a conserved target of anti-picornavirus compounds. In the present study, PI4KB was identified as the direct target of the plant-derived anti-picornavirus compounds, oxoglaucine and pachypodol (also known as Ro 09-0179). PI4KB was also ident...

journal_title：Microbiology and immunology

authors： Arita M,Philipov S,Galabov AS

更新日期：2015-06-01 00:00:00

abstract：:The botulinum neurotoxin light chain (BoNT-LC) is a zinc-dependent metalloprotease that cleaves neuronal SNARE proteins such as SNAP-25, VAMP2, and Syntaxin1. This cleavage interferes with the neurotransmitter release of peripheral neurons and results in flaccid paralysis. SNAP, VAMP, and Syntaxin are representative o...

journal_title：Microbiology and immunology

authors： Yamamoto H,Ida T,Tsutsuki H,Mori M,Matsumoto T,Kohda T,Mukamoto M,Goshima N,Kozaki S,Ihara H

更新日期：2012-04-01 00:00:00

abstract：:Shigella sonnei, which has generally been associated with dysentery in developed countries, has recently been emerging in developing countries. Specifically, in Brazil few published studies have that molecularly characterized this species. The aims of this study were to analyze the efficacy of typing using multiple-lo...

journal_title：Microbiology and immunology

authors： Seribelli AA,Frazão MR,Medeiros MIC,Stehling EG,Falcão JP

更新日期：2017-12-01 00:00:00

abstract：:The fusion of BHK-21-KB cells by vesicular stomatitis virus was not induced in Eagle's minimal essential medium without glucose. In medium containing glucose, the rate of polykaryocyte formation decreased as the concentration of glucose was reduced below 5 mM. However, no reduction in virus production 24 hr after infe...

journal_title：Microbiology and immunology

authors： Takehara M

更新日期：1981-01-01 00:00:00

abstract：:Antiplague indirect hemagglutination tests were investigated with Yersinia pestis fraction-I antigen and sera from experimentally infected rodents. The same tests with sera treated with acetone or acetone-2-mercaptoethanol were performed in parallel. Technical conditions were determined to insure the specificity and r...

journal_title：Microbiology and immunology

authors： Suzuki S,Hotta S

更新日期：1979-01-01 00:00:00

abstract：:Dengue virus multiplication in cultures of a murine myelomonocytic cell line (WEHI-3) as well as mouse peritoneal macrophages was enhanced by treatment of the cells with lipophilic derivatives of muramyl peptides for 2 or 3 days before virus inoculation, but not for 2 hr before virus inoculation or during the adsorpti...

journal_title：Microbiology and immunology

authors： Hotta H,Sanchez LF,Takada H,Homma M,Kotani S

更新日期：1985-01-01 00:00:00

abstract：:Streptococcus suis infection induces formation of neutrophil extracellular traps (NETs) in vitro; however, the contribution of NETs-mediated killing to the pathogenesis of S. suis in vivo is yet to be elicited. The findings of the present study indicated that extracellular DNA fiber can be induced in a murine model in...

journal_title：Microbiology and immunology

authors： Zhao J,Lin L,Fu L,Han L,Zhang A

更新日期：2016-04-01 00:00:00

abstract：:Using a new plaque cloning technique, we obtained unique Chlamydia trachomatis strains which were confirmed to be free of the 7.5-kb common plasmid and glycogen in inclusions. The in vitro susceptibility of these strains to various chemotherapeutic agents was tested by comparison with their parent strains and clinical...

journal_title：Microbiology and immunology

authors： Miyashita N,Matsumoto A,Matsushima T

更新日期：2000-01-01 00:00:00

abstract：:By subcutaneous inoculation of 10(8) CFU of enterohemorrhagic E. coli O157:H7, specific-pathogen-free mice revealed most of the symptoms and histological changes observed in patients. The histological changes in intestine were mainly seen in the distal parts of small intestine and the cecum. Vacuolation of villi in th...

journal_title：Microbiology and immunology

authors： Lai XH,Xu JG,Liu BY

更新日期：1991-01-01 00:00:00

abstract：:To clarify the epidemiology of viral acute respiratory infections (ARIs), 305 human parainfluenza virus types 1 (HPIV1), 154 HPIV2 and 574 HPIV3 strains were isolated from 16,962 nasopharyngeal swabs obtained between 2002 and 2011 at pediatric clinics in Yamagata, Japan. The total isolation frequency for HPIV1-3 was 6...

journal_title：Microbiology and immunology

authors： Mizuta K,Abiko C,Aoki Y,Ikeda T,Itagaki T,Katsushima F,Katsushima Y,Matsuzaki Y,Noda M,Kimura H,Ahiko T

更新日期：2012-12-01 00:00:00