The presence of antibodies against the AD2 epitope of cytomegalovirus glycoprotein B is associated with acute rejection after renal transplantation.

Abstract:

:The aim of this study was to evaluate the association between antibodies against cytomegalovirus (CMV) glycoprotein B (gB) and acute rejection after transplantation. Seventy-seven consecutive renal transplant recipients in a D + /R+ setting were studied. Biopsy-proven rejection occurred in 35% of the recipients. Among these recipients, 85% had antibodies against CMV gB. The rate of acute rejection was significantly higher in recipients with antibodies against gB than in those without them. Antibodies against gB can be a useful predictor of acute rejection in renal transplant recipients in a D + /R+ setting.

journal_name

Microbiol Immunol

authors

Ishibashi K,Tokumoto T,Shirakawa H,Oguro T,Yanagida T,Takahashi N,Nomiya M,Haga N,Aikawa K,Tanabe K,Inoue N,Kojima Y,Suzutani T

doi

10.1111/1348-0421.12112

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

72-5

issue

1

eissn

0385-5600

issn

1348-0421

journal_volume

58

pub_type

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