Interferon induction in murine peritoneal macrophage by stimulation with Lactobacillus acidophilus.

Abstract:

:Induction of interferon for a kind of dairy lactic acid bacteria, Lactobacillus acidophilus (L. acidophilus), was investigated in murine peritoneal macrophage (M phi) cultures. Lactobacillus acidophilus JCM 1034, 1132T, 1229 and 2125 induced IFN (12-34 I.U./ml) in M phi cultures in vitro. Strain 1132T- and 2125-induced IFNs were characterized as IFN alpha/beta by treatment with anti-IFNs serum. The results indicate that the inducing activity of IFNs may be one of the available biological parameters for designating the dairy products containing L. acidophilus as "physiologically functional foods."

journal_name

Microbiol Immunol

authors

Kitazawa H,Matsumura K,Itoh T,Yamaguchi T

doi

10.1111/j.1348-0421.1992.tb01668.x

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

311-5

issue

3

eissn

0385-5600

issn

1348-0421

journal_volume

36

pub_type

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