Requirement of carbohydrates for cell fusion induced by vesicular stomatitis virus.

Abstract:

:The fusion of BHK-21-KB cells by vesicular stomatitis virus was not induced in Eagle's minimal essential medium without glucose. In medium containing glucose, the rate of polykaryocyte formation decreased as the concentration of glucose was reduced below 5 mM. However, no reduction in virus production 24 hr after infection was seen under this condition. Addition of pyruvate or mannose to the culture medium caused a reversal of cell fusing activity. Cell fusion and virus growth were significantly suppressed by sodium azide and 2,4-dinitrophenol.

journal_name

Microbiol Immunol

authors

Takehara M

doi

10.1111/j.1348-0421.1981.tb00039.x

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

377-85

issue

4

eissn

0385-5600

issn

1348-0421

journal_volume

25

pub_type

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