Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action.

Abstract:

:The effect of human normal serum (HNS) on Pseudomonas pseudomallei was determined. It is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. Ancillary experiments to confirm this serum-resistant property of P. pseudomallei were done by examining the effects of growth phase conditions of the bacteria (i.e., logarithmic and stationary phases) and different buffered systems used as diluent in our bactericidal assay. Results obtained showed similar degree of resistance to serum bactericidal killing by 5 strains of the organisms tested. The possible survival advantage of serum-resistance property to P. pseudomallei as bacterial pathogens known to invade the blood stream is discussed.

journal_name

Microbiol Immunol

authors

Ismail G,Razak N,Mohamed R,Embi N,Omar O

doi

10.1111/j.1348-0421.1988.tb01426.x

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

645-52

issue

7

eissn

0385-5600

issn

1348-0421

journal_volume

32

pub_type

杂志文章
  • Colonization and turnover of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in otitis-prone children.

    abstract::Recurrent otitis media are frequently intractable during childhood. It is unclear whether recurrent otitis media is caused by etiological bacteria colonization or by new infections. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis were isolated from the nasopharynx of 7 otitisprone and 2 non-...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2007.tb03904.x

    authors: Yokota S,Harimaya A,Sato K,Somekawa Y,Himi T,Fujii N

    更新日期:2007-01-01 00:00:00

  • Differential regulation of HLA-DR expression and antigen presentation in Toxoplasma gondii-infected melanoma cells by interleukin 6 and interferon gamma.

    abstract::CD4+ cytotoxic T lymphocytes (CTL) clones, YT-4 and YT-9, specific for Toxoplasma gondii (T. gondii)-infected melanoma SK-MEL 28 (P36), were generated from the peripheral blood lymphocytes (PBL) of a patient with chronic toxoplasmosis. These CTL clones were shown to secrete significant amounts of interleukin 6 (IL-6) ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1996.tb01091.x

    authors: Yang TH,Aosai F,Norose K,Ueda M,Yano A

    更新日期:1996-01-01 00:00:00

  • Translocation domain of botulinum neurotoxin A subtype 2 potently induces entry into neuronal cells.

    abstract::Botulinum neurotoxin (BoNT) is the causative agent of botulism in humans and animals. Only BoNT serotype A subtype 1 (BoNT/A1) is used clinically because of its high potency and long duration of action. BoNT/A1 and BoNT/A subtype 2 (BoNT/A2) have a high degree of amino acid sequence similarity in the light chain (LC) ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12796

    authors: Kohda T,Tsukamoto K,Torii Y,Kozaki S,Mukamoto M

    更新日期:2020-07-01 00:00:00

  • Effect of disruption by sonication under different conditions on the activity of glucose dehydrogenase from resting spores of Bacillus subtilis.

    abstract::The activity of glucose dehydrogenase present in resting spores of Bacillus subtilis varied strikingly with the conditions for disrupting the spores by sonic treatment, namely, the time and strength of sonication, and the type and pH of the solution used for suspending the spores. When the resting spores were sonicate...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1983.tb00639.x

    authors: Tochikubo K,Yasuda Y

    更新日期:1983-01-01 00:00:00

  • Differential induction of type I interferons in macaques by wild-type measles virus alone or with the hemagglutinin protein of the Edmonston vaccine strain.

    abstract::Measles vaccines are highly effective and safe; however, the mechanism(s) underlying their attenuation has not been well understood. In this study, type I IFNs (IFN-α and IFN-β) induction in macaques infected with measles virus (MV) strains was examined. Type I IFNs were not induced in macaques infected with wild-type...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12392

    authors: Van Nguyen N,Kato SI,Nagata K,Takeuchi K

    更新日期:2016-07-01 00:00:00

  • Effects of the administration of cholera toxin as a mucosal adjuvant on the immune and protective response induced by Proteus mirabilis MrpA fimbrial protein in the urinary tract.

    abstract::Proteus mirabilis is commonly associated with complicated UTI and expresses several virulence factors, including MR/P fimbriae. In the present study mice were immunised nasally with MrpA, the structural subunit of MR/P, with or without CT as a mucosal adjuvant. The animals were then challenged with P. mirabilis and in...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2009.00111.x

    authors: Scavone P,Rial A,Umpierrez A,Chabalgoity A,Zunino P

    更新日期:2009-04-01 00:00:00

  • Immune responses against allogeneic and syngeneic tumors in aged C57BL/6 mice.

    abstract::Aged C57BL/6 (B6) mice could reject allogeneic BALB/c RL male 1 tumor as efficiently as young B6 mice. However, in vitro analysis showed impaired generation of cytotoxic T cell response in aged B6 mice against allogeneic tumor. The reaction could be augmented by the addition of recombinant interleukin-2 (rIL-2). Enzym...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2002.tb02728.x

    authors: Win S,Uenaka A,Nakayama E

    更新日期:2002-01-01 00:00:00

  • Functional analysis of the type III secretion system in enteropathogenic Escherichia coli O157:H45.

    abstract::A mass outbreak of Escherichia coli O157:H45 was first reported in Japan in 1998. This pathogen was classified as an enteropathogenic E. coli (EPEC) O157 because it was characterized by the Shiga toxin gene (stx)-negative and bundle-forming pilus (bfp) gene-positive genotypes. In this study, we investigated the type I...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2000.tb02574.x

    authors: Abe A,Nagano H

    更新日期:2000-01-01 00:00:00

  • Physical and functional map of an amikacin-resistance plasmid isolated from a multiresistant strain of Serratia marcescens.

    abstract::pTK159, a multiresistance 40-kilobase (kb) plasmid, was isolated from a clinical strain of Serratia marcescens. pTK159 was nonconjugative and carried determinants for resistance to amikacin, streptomycin/spectinomycin, sulfamethoxazole and ampicillin. A physical and functional map of pTK159 was constructed. By cloning...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1988.tb01384.x

    authors: Kanno R

    更新日期:1988-01-01 00:00:00

  • WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases.

    abstract::The Wilms' tumor gene WT1 is overexpressed in various types of solid tumors, including lung and breast cancer and WT1 protein is a tumor antigen for these malignancies. In phase I clinical trials of WT1 peptide-based cancer immunotherapy, two patients with advanced lung cancer were intradermally injected with 0.3 mg o...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2004.tb03503.x

    authors: Tsuboi A,Oka Y,Osaki T,Kumagai T,Tachibana I,Hayashi S,Murakami M,Nakajima H,Elisseeva OA,Fei W,Masuda T,Yasukawa M,Oji Y,Kawakami M,Hosen N,Ikegame K,Yoshihara S,Udaka K,Nakatsuka S,Aozasa K,Kawase I,Sugiyama H

    更新日期:2004-01-01 00:00:00

  • In situ infiltration of natural killer-like cells induced by intradermal injection of the nucleic acid fraction from BCG.

    abstract::Intradermal injection of MY-1, a nucleic acid fraction extracted from Mycobacterium bovis strain BCG, induced in situ infiltration of mononuclear cells, most of which were asialo GM1 (GA1)-positive as determined by immunofluorescence microscopy. The infiltration occurred with as little as 1 microgram of MY-1 and laste...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1989.tb00980.x

    authors: Kuramoto E,Toizumi S,Shimada S,Tokunaga T

    更新日期:1989-01-01 00:00:00

  • A mouse model of the pathogenesis and postexposure prophylaxis of rabies.

    abstract::A mouse model for the study of postexposure prophylaxis of rabies was established. Mice injected intramuscularly with a street strain of rabies virus were significantly protected from death by five daily 0.2-ml doses of inactivated rabies vaccine of chick embryo cell culture origin initiated immediately or 3 hr after ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1980.tb02888.x

    authors: Mifune K,Shichijo A,Makino Y,Takeuchi E,Yamada A,Sakamoto K

    更新日期:1980-01-01 00:00:00

  • Mucosal immunoregulation: environmental lipopolysaccharide and GALT T lymphocytes regulate the IgA response.

    abstract::In this review, we have emphasized: 1) bacterial lipopolysaccharide (LPS) involvement in IgA responses to orally administered thymic-dependent (TD) antigens; 2) characterization of Peyer's patch (PP) lymphoreticular cells; and 3) gastrointestinal immunization with gram negative pathogens and anti-LPS immunity to infec...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1348-0421.1984.tb00679.x

    authors: McGhee JR,Michalek SM,Kiyono H,Eldridge JH,Colwell DE,Williamson SI,Wannemuehler MJ,Jirillo E,Mosteller LM,Spalding DM

    更新日期:1984-01-01 00:00:00

  • Differences between surface antigenic determinants of polar monotrichous flagella of Vibrio parahaemolyticus and of related species.

    abstract::Polar monotrichous flagella (M-flagella) of Vibrio parahaemolyticus have antigens in common with those of various species of Vibrio including V. cholerae and V. anguillarum, and of Beneckea, revealed by gel diffusion tests with flagelli monomers. However, antiserum against M-flagellin of V. parahaemolyticus did not ag...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1980.tb02845.x

    authors: Shinoda S,Senoh T,Asano K,Nakahara N,Ono B

    更新日期:1980-01-01 00:00:00

  • A single-stranded DNA aptamer against mannose-capped lipoarabinomannan enhances anti-tuberculosis activity of macrophages through downregulation of lipid-sensing nuclear receptor peroxisome proliferator-activated receptor γ expression.

    abstract::Mannose-capped lipoarabinomannan (ManLAM) is an immunomodulatory epitope of Mycobacterium tuberculosis (Mtb). An aptamer (ZXL1) that specifically binds to ManLAM from the virulent Mtb H37Rv strain was previously generated and it was found that ZXL1 functions as an antagonist, inhibiting the ManLAM-induced immunosuppre...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12470

    authors: Pan Q,Yan J,Liu Q,Yuan C,Zhang XL

    更新日期:2017-02-01 00:00:00

  • Crystallization and some properties of leukocidin from Pseudomonas aeruginosa.

    abstract::A leukocidin was isolated and purified from autolysates of Pseudomonas aeruginosa strain 158 by a combination of procedures such as column chromatography on DEAE-Sephadex A-50, gel filtration on Sephadex G-100, and zone electrophoresis on pevikon. The purified preparation showed a single band in each experiment using ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1983.tb00619.x

    authors: Hirayama T,Kato I,Matsuda F,Noda M

    更新日期:1983-01-01 00:00:00

  • Macrophage migration inhibitory factor (MIF) produced by a human T cell hybridoma clone.

    abstract::A human T cell hybridoma clone, F5, producing high levels of macrophage migration inhibitory factor (MIF) was established by the emetine-actinomycin D selection method. This clone produced two species of MIF which were separated on a Phenyl Sepharose column. We purified MIF-2 (the more hydrophobic species of the two) ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1991.tb01552.x

    authors: Hirose S,Ooki S,Higuchi M,Osawa T

    更新日期:1991-01-01 00:00:00

  • Difference in response of NK cell activity in newborns and adult to IL-2, IL-12 and IL-15.

    abstract::The killing activity of cord blood mononuclear cells (cMNC) against cytomegalovirus (CMV)-uninfected and -infected fibroblasts was comparable to that of adult peripheral blood mononuclear cells (aPBMC). The killing activity of cMNC against K562 cells was significantly lower compared with that of aPBMC. Treatment of cM...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1999.tb02387.x

    authors: Hoshina T,Kida K,Ito M

    更新日期:1999-01-01 00:00:00

  • Identification of heat-stable enterotoxin-producing strains of Yersinia enterocolitica and Vibrio cholerae non-O1 by a monoclonal antibody-based enzyme-linked immunosorbent assay.

    abstract::Using a mouse monoclonal antibody (MAb) 2F raised against Vibrio cholerae non-O1 heat-stable enterotoxin (NAG-ST) which also recognizes a shared epitope of Yersinia enterocolitica heat-stable enterotoxin (Y-ST), a competitive enzyme-linked immunosorbent assay (ELISA) was developed for independent detection of NAG-ST a...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1993.tb03198.x

    authors: Nair GB,Bhattacharya SK,Takeda T

    更新日期:1993-01-01 00:00:00

  • Capsule of Streptococcus pyogenes is essential for delayed death of mice in a model of streptococcal toxic shock syndrome.

    abstract::We have previously reported a mouse model of severe group A streptococcal infection (Microbiol. Immunol. 45: 777-786, 2001). When we injected Streptococcus pyogenes strains intramuscularly, the mice suffered from acute phase of infection for a few days but recovered from the illness and gained body weight. These mice,...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2006.tb03777.x

    authors: Iida K,Seki M,Saito M,Kawamura Y,Kajiwara H,Yoshida S

    更新日期:2006-01-01 00:00:00

  • Influenza A virus protein PA-X suppresses host Ankrd17-mediated immune responses.

    abstract::Influenza A virus (IAV) PA-X is a critical ribonuclease protein involved in host cell shutoff but its role in modulating the host immune response to IAV infection remains to be addressed. In this study, host cellular proteins that directly interact with PA-X were screened to investigate the biological function of PA-X...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/1348-0421.12863

    authors: Li M,Qi W,Chang Q,Chen R,Zhen D,Liao M,Wen J,Deng Y

    更新日期:2020-11-26 00:00:00

  • Induction of protective immunity by primed B-1 cells in Toxoplasma gondii -infected B cell-deficient mice.

    abstract::We examined the role of B-1 cells in protection against Toxoplasma gondii infection using B cell-deficient mice (muMT mice). We found that primed but not naïve B-1 cells from wild-type C57BL/6 mice protected B cell-deficient recipients from challenge infection. All muMT mice transferred with primed B-1 cells survived ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2003.tb03460.x

    authors: Chen M,Mun HS,Piao LX,Aosai F,Norose K,Mohamed RM,Belal US,Fang H,Ahmed AK,Kang HK,Matsuzaki G,Kitamura D,Yano A

    更新日期:2003-01-01 00:00:00

  • Transcriptional control plays an important role for the production of heat-labile enterotoxin in enterotoxigenic Escherichia coli of human origin.

    abstract::The production of heat-labile enterotoxin (LT) in 76 strains of human enterotoxigenic Escherichia coli (ETEC) varied by a factor of 100. Three ETEC strains that differ in the levels of LT production were chosen for the cloning of LT genes (toxAB) into plasmid pBR322, and the gene structure and expression were compared...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1990.tb00987.x

    authors: Katayama S,Ninomiya M,Minami J,Okabe A,Hayashi H

    更新日期:1990-01-01 00:00:00

  • Pyrogenicity of yeast mannans in rabbits.

    abstract::A few yeast mannans free from protein and phosphorus showed pyrogenic activity in rabbits although the extent of this activity was considerably lower than that of the bacterial lipopolysaccharides (LPS). The pyrogenic activity was not abolished by treatment with sodium deoxycholate. This result showed that the mannans...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1984.tb00719.x

    authors: Nagase T,Mikami T,Suzuki S,Suzuki M

    更新日期:1984-01-01 00:00:00

  • Elevated plasma levels of P-selectin (GMP-140/CD62P) in patients with Plasmodium falciparum malaria.

    abstract::The plasma concentration of soluble P-selectin (GMP-140/CD62P/PADGEM), a selectin produced by activated platelets and endothelial cells, was quantitated in a group of adults and East African negro children presenting with either non-severe or severe (cerebral) malaria caused by Plasmodium falciparum. Sixty percent of ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1994.tb01848.x

    authors: Facer CA,Theodoridou A

    更新日期:1994-01-01 00:00:00

  • Staphylococcus aureus requires increased level of Ca(2+) or Mn(2+) to grow normally in a high-NaCl/low-Mg(2+) medium.

    abstract::Mg2+-availability in Staphylococcus aureus cells decreased significantly with increasing NaCl concentration in growth media. Cells grew in a NaCl-free, Chelex resin-treated complex medium only if the medium was supplemented with 50 microM MgCl2, while, growth was limited when the medium was further supplemented with 1...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.2001.tb01313.x

    authors: Ochiai T

    更新日期:2001-01-01 00:00:00

  • Amino acid requirements for the growth of Aedes albopictus clone C6/36 cells and for the production of dengue and Chikungunya viruses in the infected cells.

    abstract::Amino acid requirements for the growth of Aedes albopictus, clone C6/36, cells and for the production of dengue (DEN) and Chikungunya (CHIK) viruses were examined by growing the cells or the viruses in media which were deprived of one of the 20 amino acids. Cell growth was markedly inhibited when cystine was omitted f...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1980.tb02897.x

    authors: Sasao F,Igarashi A,Fukai K

    更新日期:1980-01-01 00:00:00

  • Identification of phosphocholine-containing glycoglycerolipids purified from Mycoplasma fermentans-infected human helper T-cell culture as components of M. fermentans.

    abstract::Previously, we have reported the occurrence of novel phosphocholine-containing glycoglycerolipids (GGPLs: GGPL-I and GGPL-III) in human helper T-cell (MT-4 cell line) (Mustuda et al, Glycoconjugate J. 10:340). However, the GGPLs disappeared from the MT-4 after treatment with an antimycoplasma agent. This disappearance...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1995.tb02206.x

    authors: Matsuda K,Harasawa R,Li JL,Kasama T,Taki T,Handa S,Yamamoto N

    更新日期:1995-01-01 00:00:00

  • Metastasis-promoting activity of a novel molecule, Ag 243-5, derived from mycoplasma, and the complete nucleotide sequence.

    abstract::We found that mycoplasma-infected cells have a higher ability to metastasize in vivo than non-mycoplasma-infected cells. To investigate this phenomenon, we obtained a monoclonal antibody, MAb 243-5, by immunization with Mycoplasma arginini-infected RPMI 4788 cells. This MAb recognized a mycoplasmal protein with an MW ...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1995.tb02218.x

    authors: Ushio S,Iwaki K,Taniai M,Ohta T,Fukuda S,Sugimura K,Kurimoto M

    更新日期:1995-01-01 00:00:00

  • Immunoelectron microscopy of Chlamydia psittaci with monoclonal antibodies.

    abstract::An immunoelectron microscopic study was performed to determine the distribution of antigenic components on particles of Chlamydia psittaci and infected cells using a number of monoclonal antibodies (MAbs). Of three anti-lipopolysaccharide (LPS) antibodies (4D5, A2 and 4G5), two antibodies (4D5 and A2) reacted with the...

    journal_title:Microbiology and immunology

    pub_type: 杂志文章

    doi:10.1111/j.1348-0421.1992.tb01648.x

    authors: Ando S,Takashima I,Hashimoto N

    更新日期:1992-01-01 00:00:00