A single-stranded DNA aptamer against mannose-capped lipoarabinomannan enhances anti-tuberculosis activity of macrophages through downregulation of lipid-sensing nuclear receptor peroxisome proliferator-activated receptor γ expression.

abstract：:We found that mycoplasma-infected cells have a higher ability to metastasize in vivo than non-mycoplasma-infected cells. To investigate this phenomenon, we obtained a monoclonal antibody, MAb 243-5, by immunization with Mycoplasma arginini-infected RPMI 4788 cells. This MAb recognized a mycoplasmal protein with an MW ...

journal_title：Microbiology and immunology

authors： Ushio S,Iwaki K,Taniai M,Ohta T,Fukuda S,Sugimura K,Kurimoto M

更新日期：1995-01-01 00:00:00

abstract：:ISG20 is an ribonuclease specific for single-stranded RNA and considered to play a role in innate immunity against virus infections. We herein show that both poly IC, an authentic double-stranded RNA, and IFN-gamma induced ISG20 expression in cultured HUVEC. Poly IC-induced ISG20 expression was inhibited by LY294002, ...

journal_title：Microbiology and immunology

authors： Imaizumi T,Mechti N,Matsumiya T,Sakaki H,Kubota K,Yoshida H,Kimura H,Satoh K

更新日期：2008-01-01 00:00:00

abstract：:The nucleic acid fraction from cells of 6 species of bacterium and 2 kinds of vertebrate, calf and salmon, was extracted and purified by the same procedures as described previously. When the spleen cells from BALB/c mice were incubated with the nucleic acid fraction from either of the bacteria, natural killer (NK) act...

journal_title：Microbiology and immunology

authors： Yamamoto S,Yamamoto T,Shimada S,Kuramoto E,Yano O,Kataoka T,Tokunaga T

更新日期：1992-01-01 00:00:00

abstract：:Staphylococcus aureus Cowan I was incubated with monolayers of cells derived from several portions of mouse kidney, and found to be ingested by all types of the renal cells. Intracellular localization of S. aureus was determined by resistance of intracellular cocci against lysostaphin digestion and confirmed by electr...

journal_title：Microbiology and immunology

authors： Murai M,Usui A,Seki K,Sakurada J,Masuda S

更新日期：1992-01-01 00:00:00

abstract：:Francisella tularensis, which causes tularemia, is widely distributed in the Northern hemisphere. F. tularensis strains isolated in Japan are genetically unique from non-Japanese strains; however, their phenotypic properties have not been well studied. Thus, mice were infected with representative Japanese strains of F...

journal_title：Microbiology and immunology

authors： Hotta A,Fujita O,Uda A,Yamamoto Y,Sharma N,Tanabayashi K,Yamada A,Morikawa S

更新日期：2016-03-01 00:00:00

abstract：:Salmonella typhimurium strain 9 produces mini-cells during cell proliferation. Mini-cells are viable but cannot proliferate since they do not contain chromosomal DNA. Effects of whole cells and mini-cells of S. typhimurium on the immune responses were investigated, with the following results. Phagocytosis of peritonea...

journal_title：Microbiology and immunology

authors： Kurashige S,Yoshida T,Kodama K,Mitsuhashi S

更新日期：1981-01-01 00:00:00

abstract：:Farnesol is well known as a quorum-sensing molecule of Candida albicans. To assess the pathological function of farnesol, its effects on macrophage viability and functions including growth inhibitory activities against C. albicans were examined in vitro. Murine macrophages, when cultured in the presence of 56-112 micr...

journal_title：Microbiology and immunology

authors： Abe S,Tsunashima R,Iijima R,Yamada T,Maruyama N,Hisajima T,Abe Y,Oshima H,Yamazaki M

更新日期：2009-06-01 00:00:00

abstract：:The aim of this study was to investigate the pathogenesis of Mycoplasma pneumoniae (MP) infection and its association with cardiac and hepatic damage. Between March 2013 and March 2014, 59 children with MP pneumonia (MPP) and 30 healthy children were enrolled. Serum titers of TLR4, T cell immunoglobulin and mucin-doma...

journal_title：Microbiology and immunology

authors： Fan Q,Meng J,Li P,Liu Z,Sun Y,Yan P

更新日期：2015-07-01 00:00:00

abstract：:We observed the effects of a chinese herb medicine Sho-saiko-to on the lethal and antitumor activities of recombinant human tumor necrosis factor (rhTNF) administered in mice. Sho-saiko-to was noted to protect the rhTNF-induced lethality in galactosamine-hypersensitized mice, and also Sho-saiko-to pretreated mice was ...

journal_title：Microbiology and immunology

authors： Sakaguchi S,Tutumi E,Yokota K,Furusawa S,Sasaki K,Takayanagi Y

更新日期：1991-01-01 00:00:00

abstract：:We examined the mechanisms of fluconazole resistance in a fluconazole-resistant Candida albicans isolate from a Japanese patient with chronic mucocutaneous candidiasis. It was demonstrated that the highly resistant phenotype of this strain was associated with combined mechanisms of the energy-dependent reduced intrace...

journal_title：Microbiology and immunology

authors： Kamai Y,Maebashi K,Kudoh M,Makimura K,Naka W,Uchida K,Yamaguchi H

更新日期：2004-01-01 00:00:00

abstract：:Leptospirosis is a worldwide zoonosis. The importance of urban leptospirosis is recognized in Japan: urban rats carry pathogenic leptospires and people acquire these pathogens through contact with surface water or soil contaminated by the urine of the infected animals. To determine the current Leptospira carriage rate...

journal_title：Microbiology and immunology

authors： Saito M,Villanueva SY,Masuzawa T,Haraguchi Y,Ita S,Miyahara S,Ozuru R,Yamaguchi T,Yoshimura M,Ikejiri M,Aramaki N,Amran MY,Muslich LT,Iida K,Yanagihara Y,Gloriani NG,Yoshida S

更新日期：2015-06-01 00:00:00

abstract：:Sodium vanadate enhanced Newcastle disease virus (NDV)-induced cell fusion in L cells, and there was a direct correlation between the degree of cell fusion and the dose of vanadate added. When anti-F protein of NDV monospecific antiserum was added to the culture fluid of L cells infected with NDV, the enhancement of c...

journal_title：Microbiology and immunology

authors： Yamamoto F,Fujioka H,Iinuma M,Takano M,Maeno K,Nagai Y,Ito Y

更新日期：1984-01-01 00:00:00

abstract：:The pea cyv1 gene is a yet-to-be-identified recessive resistance gene that inhibits the infection of clover yellow vein virus (ClYVV). Previous studies confirmed that the cell-to-cell movement of ClYVV is inhibited in cyv1-carrying pea plants; however, the effect of cyv1 on viral replication remains unknown. In this s...

journal_title：Microbiology and immunology

authors： Taninaka Y,Nakahara KS,Hagiwara-Komoda Y

更新日期：2020-01-01 00:00:00

abstract：:A chemotaxonomic study was carried out on 31 strains of non-O1 Vibrio cholerae bio-serogroup Hakata, isolated in Japan, which possesses the Inaba antigen C of O1 V. cholerae. On the basis of the compositional sugar pattern of the polysaccharide portion of their lipopolysaccharides, the 23 strains isolated from the env...

journal_title：Microbiology and immunology

authors： Kondo S,Iguchi T,Haishima Y,Isshiki Y,Hisatsune K

更新日期：1989-01-01 00:00:00

abstract：:We performed a cluster analysis of human and animal pathogenic Microsporum species and their teleomorphic states, Arthroderma species, including A. otae-related species (M. canis, M. audouinii, M. distortum, M. equinum, M. langeronii, and M. ferrugineum) and M. gypseum complex (A. fulvum, A. gypseum, and A. incurvatum...

journal_title：Microbiology and immunology

authors： Makimura K,Tamura Y,Murakami A,Kano R,Nakamura Y,Hasegawa A,Uchida K,Yamaguchi H

更新日期：2001-01-01 00:00:00

abstract：:The ability of 33 compounds of L-alanine analogues over a wide range of concentrations to initiate germination of Bacillus subtilis spores was determined, and the inhibitory activity against L-alanine-initiated germination was determined for the above compounds and 22 of their D- and DL-isomers. Nineteen L-isomers wer...

journal_title：Microbiology and immunology

authors： Yasuda Y,Tochikubo K

更新日期：1985-01-01 00:00:00

abstract：:Measles vaccines are highly effective and safe; however, the mechanism(s) underlying their attenuation has not been well understood. In this study, type I IFNs (IFN-α and IFN-β) induction in macaques infected with measles virus (MV) strains was examined. Type I IFNs were not induced in macaques infected with wild-type...

journal_title：Microbiology and immunology

authors： Van Nguyen N,Kato SI,Nagata K,Takeuchi K

更新日期：2016-07-01 00:00:00

abstract：:Many studies have proved the relevance of local immune responses, rather than systemic immunity, to the pathogenesis of allergic rhinitis. Indeed, allergen-specific B lymphocyte undergoes class switching to IgE in situ. However, the relative contribution of in situ production to the amount in serum is still ambiguous....

journal_title：Microbiology and immunology

authors： Yoshida T,Usui A,Kusumi T,Inafuku S,Sugiyama T,Koide N,Yokochi T

更新日期：2005-01-01 00:00:00

abstract：:There was a significant amount of non-specific, but not of allergen (e.g., papain, mite feces and four kinds of pollen)-specific, IgE antibodies (Abs) in the sera of normal mice. An i.n. injection of each allergen without adjuvant into mice caused an increase in total IgE Ab titers with a similar time course in the se...

journal_title：Microbiology and immunology

authors： Hannya N,Ogita-Nakanishi H,Kato R,Ijiri Y,Hayashi T,Tanaka K,Kawata R,Takenaka H,Kubota T,Yoshida R

更新日期：2018-02-01 00:00:00

abstract：:Viable but nonculturable (VBNC) Vibrio cholerae non-O1/non-O139, V. parahaemolyticus, enterohemorrhagic Escherichia coli, enterotoxigenic E. coli, enteropathogenic E. coli, Shigella flexneri, and Salmonella enterica were converted to the culturable state by co-culture with selected eukaryotic cells, e.g., HT-29, Caco-...

journal_title：Microbiology and immunology

authors： Senoh M,Ghosh-Banerjee J,Ramamurthy T,Colwell RR,Miyoshi S,Nair GB,Takeda Y

更新日期：2012-05-01 00:00:00

abstract：:Stromal cell-derived factor-1 (SDF-1) is an efficacious chemoattractant for lymphocytes, monocytes and hematopoietic progenitor cells. In the present study, we examined whether SDF-1 has growth promoting activity on human peripheral T cells and analyzed the possible underlying signal transduction pathways. SDF-1 augme...

journal_title：Microbiology and immunology

authors： Yonezawa A,Hori T,Sakaida H,Uchiyama T

更新日期：2000-01-01 00:00:00

abstract：:We have previously reported a mouse model of severe group A streptococcal infection (Microbiol. Immunol. 45: 777-786, 2001). When we injected Streptococcus pyogenes strains intramuscularly, the mice suffered from acute phase of infection for a few days but recovered from the illness and gained body weight. These mice,...

journal_title：Microbiology and immunology

authors： Iida K,Seki M,Saito M,Kawamura Y,Kajiwara H,Yoshida S

更新日期：2006-01-01 00:00:00

abstract：:Many pathogens colonize host tissues by binding to the extracellular matrix via their cell surface adhesion molecules, which are called MSCRAMMs (microbial surface components recognizing adhesive matrix molecules). Staphylococcus aureus expresses several of these adhesion molecules, some of which bind to fibronectin. ...

journal_title：Microbiology and immunology

authors： Shinji H,Kamada M,Seki K,Tajima A,Iwase T,Masuda S

更新日期：2007-01-01 00:00:00

abstract：:The 16S toxin was purified from a Clostridium botulinum type D strain 1873 (D-1873). Furthermore, the entire nucleotide sequences of the genes coding for the 16S toxin were determined. It became clear that the purified D-1873 16S toxin consists of neurotoxin, nontoxic nonhemagglutinin (NTNH), and hemagglutinin (HA), a...

journal_title：Microbiology and immunology

authors： Nakajima H,Inoue K,Ikeda T,Fujinaga Y,Sunagawa H,Takeshi K,Ohyama T,Watanabe T,Inoue K,Oguma K

更新日期：1998-01-01 00:00:00

abstract：:Us3 is a serine-threonine protein kinase that is encoded by herpes simplex virus 1 (HSV-1). In experimental animal models of HSV infection, peripheral and intracranial inoculations can be used to study viral pathogenicity in peripheral sites (e.g., eyes and vagina) and central nervous systems (CNSs), respectively. In ...

journal_title：Microbiology and immunology

authors： Koyanagi N,Imai T,Arii J,Kato A,Kawaguchi Y

更新日期：2014-01-01 00:00:00

abstract：:Interferon stimulated gene 15 (ISG15), an ubiquitin cross-reactive protein, can conjugate to target proteins. Unlike ubiquitination, protein modification by ISG15 does not target protein for degradation, but enhances the cellular response to interferon (IFN), which plays a key role in antiviral responses. In this stud...

journal_title：Microbiology and immunology

authors： Yang L,Zhang LY,Wang C,Wang B,Wang XM,Zeng SM

更新日期：2012-03-01 00:00:00

abstract：:We have developed a convenient method for assaying the receptor-destroying enzyme (RDE) activity of influenza C virus. This method measures the ability of the RDE to destroy the hemagglutination-inhibition activity of a potent inhibitor present in rat serum. Some physico-chemical properties of the RDE of influenza C v...

journal_title：Microbiology and immunology

authors： Sugawara K,Kitame F,Homma M,Nakamura K

更新日期：1985-01-01 00:00:00

abstract：:The polymerase chain reaction (PCR) was applied for the etiological diagnosis of spotted fever group (SFG) rickettsiosis in Japan. Nucleotide primers derived from the 17-kDa antigen gene of Rickettsia rickettsii primed a rickettsia-specific 246-base-pair product for all of the Katayama, Abe, Misaka and Kojima strains,...

journal_title：Microbiology and immunology

authors： Tange Y,Matsumoto M,Okada T,Hasegawa H,Kobayashi Y

更新日期：1994-01-01 00:00:00

abstract：:The attachment of Mycoplasma pulmonis m53 organisms to mouse and rat synovial cells was examined by using the organisms and the synovial cells treated in various ways. M. pulmonis treated with trypsin attached to the synovial cells, but the organisms treated with pronase, formaldehyde, glutaraldehyde, or heat did not....

journal_title：Microbiology and immunology

authors： Araake M,Yayoshi M,Yoshioka M

更新日期：1985-01-01 00:00:00

abstract：:M protein is an important virulence determinant in Streptococcus pyogenes, but the amounts of M protein in various strains of the species remain to be elucidated. To assess the amount of M protein in strains of each emm genotype, dot blot analysis was performed on 141 clinically isolated strains. Among the cell membra...

journal_title：Microbiology and immunology

authors： Matsumoto M,Suzuki M,Hirose K,Hiramatsu R,Minagawa H,Minami M,Tatsuno I,Okamoto A,Ohta M,Hasegawa T

更新日期：2011-06-01 00:00:00