Differential induction of type I interferons in macaques by wild-type measles virus alone or with the hemagglutinin protein of the Edmonston vaccine strain.

abstract：:We investigated here the kinetics of natural killer (NK) cells and extrathymic T cells, which include intermediate CD3 cells and gamma delta T cells, in the cord factor-induced granulomatous inflammation of the lungs and liver. In Balb/c mice, pulmonary inflammation elevated the proportion of NK cells and that of extr...

journal_title：Microbiology and immunology

authors： Tabata A,Kaneda K,Watanabe H,Abo T,Yano I

更新日期：1996-01-01 00:00:00

abstract：:Rabies virus Nishigahara strain causes lethal infection in adult mice after intracerebral inoculation. On the other hand, the RC-HL strain, derived from the Nishigahara strain, does not cause lethal infection in adult mice. We previously demonstrated that a chimeric virus, R(G), with the open reading frame of the G ge...

journal_title：Microbiology and immunology

authors： Yamada K,Ito N,Takayama-Ito M,Sugiyama M,Minamoto N

更新日期：2006-01-01 00:00:00

abstract：:The lack of a suitable animal model is a major obstacle to developing anti-HIV-1 vaccines. We successfully generated an SIVmac/HIV-1 chimeric virus (SHIV) (designated as NM-3rN) that contains the HIV-1 env gene and is infectious to macaque monkeys. Challenging the vaccinated macaque monkeys with NM-3rN, we developed a...

journal_title：Microbiology and immunology

authors： Haga T,Kuwata T,Ui M,Igarashi T,Miyazaki Y,Hayami M

更新日期：1998-01-01 00:00:00

abstract：:A recombinant pertussis DNA vaccine was described here with its immunogenicity and the ability to induce protection against B. pertussis infection in mice. Three immunodominant antigen gene fragments of pertussis, pertussis toxin subunit 1 (pts1), fragments of pertactin (prn) and filamentous hemagglutinin (fha), were ...

journal_title：Microbiology and immunology

authors： Li Q,Zhu Y,Chu J,Wang Y,Xu Y,Hou Q,Zhang S,Guo X

更新日期：2006-01-01 00:00:00

abstract：:The Wilms' tumor gene WT1 is overexpressed in various types of solid tumors, including lung and breast cancer and WT1 protein is a tumor antigen for these malignancies. In phase I clinical trials of WT1 peptide-based cancer immunotherapy, two patients with advanced lung cancer were intradermally injected with 0.3 mg o...

journal_title：Microbiology and immunology

authors： Tsuboi A,Oka Y,Osaki T,Kumagai T,Tachibana I,Hayashi S,Murakami M,Nakajima H,Elisseeva OA,Fei W,Masuda T,Yasukawa M,Oji Y,Kawakami M,Hosen N,Ikegame K,Yoshihara S,Udaka K,Nakatsuka S,Aozasa K,Kawase I,Sugiyama H

更新日期：2004-01-01 00:00:00

abstract：:B lymphocytes express multiple TLRs that regulate their cytokine production.We investigated the effect of TLR4 and TLR9 activation on receptor activator of NF‐kB ligand (RANKL) expression by rat spleen B cells. Splenocytes or purified spleen B cells from Rowett rats were cultured with TLR4 ligand Escherichia coli LPS ...

journal_title：Microbiology and immunology

authors： Yu X,Lin J,Yu Q,Kawai T,Taubman MA,Han X

更新日期：2014-01-01 00:00:00

abstract：:Histopathological observations of changes at the injection site in mice were made for 20 weeks after a single intramuscular (im) injection of aluminum hydroxide-adsorbed tetanus toxoid (Alum-TT), plain tetanus toxoid (TT), or aluminum adjuvant (Alum alone). Marked injury to muscle fibers and infiltration of neutrophil...

journal_title：Microbiology and immunology

authors： Goto N,Akama K

更新日期：1982-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) non-structural protein 5A (NS5A) is a multifunctional protein that is involved in the HCV life cycle and pathogenesis. In this study, a host protein(s) interacting with NS5A by tandem affinity purification were searched for with the aim of elucidating the role of NS5A. An NS5A-interacting prote...

journal_title：Microbiology and immunology

authors： Chen M,Gan X,Yoshino K,Kitakawa M,Shoji I,Deng L,Hotta H

更新日期：2016-06-01 00:00:00

abstract：:It has been suggested that infectious entry of rubella virus (RV) is conducted by receptor mediated endocytosis. To explore the cellular entry mechanism of RV, inhibitory effects of drugs affecting various endocytic pathways on RV entry into VeroE6 cells were analyzed. Results showed that RV infectious entry into Vero...

journal_title：Microbiology and immunology

authors： Kee SH,Cho EJ,Song JW,Park KS,Baek LJ,Song KJ

更新日期：2004-01-01 00:00:00

abstract：:We found that mycoplasma-infected cells have a higher ability to metastasize in vivo than non-mycoplasma-infected cells. To investigate this phenomenon, we obtained a monoclonal antibody, MAb 243-5, by immunization with Mycoplasma arginini-infected RPMI 4788 cells. This MAb recognized a mycoplasmal protein with an MW ...

journal_title：Microbiology and immunology

authors： Ushio S,Iwaki K,Taniai M,Ohta T,Fukuda S,Sugimura K,Kurimoto M

更新日期：1995-01-01 00:00:00

abstract：:The colH gene encoding 116-kDa collagenase of Clostridium histolyticum (cColH) was cloned into an Escherichia coli-Bacillus subtilis shuttle vector to develop a method for purification of recombinant collagenase (rColH). When plasmid pJCM310 containing the colH gene was introduced into B. subtilis DB104 and the transf...

journal_title：Microbiology and immunology

authors： Jung CM,Matsushita O,Katayama S,Minami J,Ohhira I,Okabe A

更新日期：1996-01-01 00:00:00

abstract：:CD4(+) T cells play critical roles in protection against the blood stage of malarial infection; however, their uncontrolled activation can be harmful to the host. In this study, in which rodent models of Plasmodium parasites were used, the expression of inhibitory receptors on activated CD4(+) T cells and their cytoki...

journal_title：Microbiology and immunology

authors： Doe HT,Kimura D,Miyakoda M,Kimura K,Akbari M,Yui K

更新日期：2016-02-01 00:00:00

abstract：:Antibodies specific to Salmonella enteritidis (S.E.) were obtained from immunized egg yolk, and their protective effects against S.E. were studied by using monolayer-cultured human intestinal epithelial cells, Caco-2 and T84. The Salmonella adherence and entry to the cells were partially inhibited by the antibodies. T...

journal_title：Microbiology and immunology

authors： Sugita-Konishi Y,Ogawa M,Arai S,Kumagai S,Igimi S,Shimizu M

更新日期：2000-01-01 00:00:00

abstract：:Alpha-fetoprotein (AFP) expression is observed in embryonic tissues and, the expression of this protein is absent in normal adult tissues. The re-elevation of serum AFP strongly suggests generation of a malignant tumor in an adult. We demonstrated here that AFP-producing gastric cancer (AFP-gastric cancer) could be tr...

journal_title：Microbiology and immunology

authors： Miura Y,Kataoka H,Joh T,Tada T,Asai K,Nakanishi M,Okada N,Okada H

更新日期：2004-01-01 00:00:00

abstract：:Enterohaemorrhagic Escherichia coli O157: H7 is an important pathogen these days. Outbreaks of its infection have been reported all over the world, in Australia, Canada, Japan, the United States, south Africa, and various countries in Europe. In the summer of 2001, the first clinical infection by E. coli O157: H7 was ...

journal_title：Microbiology and immunology

authors： Tsai TY,Luo WC,Wu FT,Pan TM

更新日期：2005-01-01 00:00:00

abstract：:Three hundred and twenty-five breast milk samples were examined for the occurrence of human cytomegalovirus (HCMV) by cell culture method. Virus was isolated from the milk in 1 of 177 samples collected within 6 days after delivery, 2 of 115 samples collected during the period of 7 days to 1 month after delivery, 10 of...

journal_title：Microbiology and immunology

authors： Hotsubo T,Nagata N,Shimada M,Yoshida K,Fujinaga K,Chiba S

更新日期：1994-01-01 00:00:00

abstract：:Effects of each of three indigenous Lactobacillus groups on other bacterial populations were separately investigated in gnotobiotic rats. In the wall of the non-glandular part of the stomach, contents of the stomach and contents of the upper part of the small intestine, some pre-associated indigenous bacteria were red...

journal_title：Microbiology and immunology

authors： Watanabe T,Morotomi M,Kawai Y,Mutai M

更新日期：1977-01-01 00:00:00

abstract：:Antisense amino acids are amino acids which can be translated from the corresponding anti-codons of a sense amino acid. Antisense peptides encoded by the noncoding DNA strand have a tendency to interact with each other. We have demonstrated that antisense peptide sequences are present intramolecularly, and these may c...

journal_title：Microbiology and immunology

authors： Imai M,Okada N,Okada H

更新日期：2000-01-01 00:00:00

abstract：:Escherichia coli isolates from calves with diarrhea (1 day to 8 weeks old, 140 individuals) were surveyed for the three immunologically distinct fimbrial adhesins FY, 31A, and K99. Of a total of 1,370 strains isolated, 96 (7.0%), 34 (2.5%), 75 (5.5%), and 13 (0.9%) were identified as FY+, 31A+, FY+.31A+, and K99+, res...

journal_title：Microbiology and immunology

authors： Shimizu M,Sakano T,Yamamoto J,Kitajima K

更新日期：1987-01-01 00:00:00

abstract：:Trehalose 6,6'-dimycolate (TDM), or cord factor, is a crucial stimulus of immune responses during Mycobacterium tuberculosis infection. Although TDM has immuno-stimulatory properties, including adjuvant activity and the ability to induce granuloma formation, the mechanisms underlying these remain unknown. We hypothesi...

journal_title：Microbiology and immunology

authors： Lee WB,Yan JJ,Kang JS,Chung S,Kim LK

更新日期：2017-12-01 00:00:00

abstract：:Specific tumor microenvironment signaling might prevent the maturation of dendritic cells (DCs) with tolerogenic and immunosuppressive potential accounting for antigen-specific unresponsiveness in the lymphoid organs and in the periphery. In the present study, dendritic cells treated with LLC lung cancer cell or 4T1 b...

journal_title：Microbiology and immunology

authors： Ma C,Su M,Shen K,Chen J,Ning Y,Qi C

更新日期：2020-01-01 00:00:00

abstract：:During the three-year period from 1984 to 1987, 506 acute gastroenteritis outbreaks involving 14,383 patients were reported to the Bureau of Public Health, Tokyo Metropolitan Government. Eighty (4,324 patients) of 150 outbreaks (4,860 patients) from which etiologic agents were not identified were subjected to virologi...

journal_title：Microbiology and immunology

authors： Sekine S,Okada S,Hayashi Y,Ando T,Terayama T,Yabuuchi K,Miki T,Ohashi M

更新日期：1989-01-01 00:00:00

abstract：:Quantitative PCR (qPCR) of human T-cell leukemia virus type 1 (HTLV-1) provirus is used for HTLV-1 testing and for assessment of risk of HTLV-1-related diseases. In this study, a reference material was developed for standardizing HTLV-1 qPCR. Freeze-dried TL-Om1 cells diluted with Jurkat cells were prepared and an ass...

journal_title：Microbiology and immunology

authors： Kuramitsu M,Okuma K,Nakashima M,Sato T,Sasaki D,Hasegawa H,Umeki K,Kubota R,Sasada K,Sobata R,Matsumoto C,Kaneko N,Tezuka K,Matsuoka S,Utsunomiya A,Koh KR,Ogata M,Ishitsuka K,Taki M,Nosaka K,Uchimaru K,Iwanaga M

更新日期：2018-10-01 00:00:00

abstract：:We performed a cluster analysis of human and animal pathogenic Microsporum species and their teleomorphic states, Arthroderma species, including A. otae-related species (M. canis, M. audouinii, M. distortum, M. equinum, M. langeronii, and M. ferrugineum) and M. gypseum complex (A. fulvum, A. gypseum, and A. incurvatum...

journal_title：Microbiology and immunology

authors： Makimura K,Tamura Y,Murakami A,Kano R,Nakamura Y,Hasegawa A,Uchida K,Yamaguchi H

更新日期：2001-01-01 00:00:00

abstract：:The in vitro effect of the heat-labile toxin (HLT) of Bordetella parapertussis on HeLa, baby hamster kidney (BHK), chinese hamster ovary (CHO), myeloma (Pa-NS-1), human embryonic lung (HEL-R66) cells, erythrocytes, adipocytes and lymphocytes from guinea pigs, mice or rats, or aortic smooth muscle cells from pigs or gu...

journal_title：Microbiology and immunology

authors： Endoh M,Nagai M,Ueda T,Yoshida Y,Nakase Y

更新日期：1988-01-01 00:00:00

abstract：:Scanning electron micrograph of HeLa S3 monolayered cells, inoculated with viable bacteria of a Salmonella typhi strain GIFU 10007, revealed that the extended microvilli tangled the bacteria within 10 min after inoculation. The micrographs of HeLa cells, at 1 hr after inoculation, indicate the following: shortening of...

journal_title：Microbiology and immunology

authors： Yokoyama H,Ikedo M,Kohbata S,Ezaki T,Yabuuchi E

更新日期：1987-01-01 00:00:00

abstract：:Three strains TKU9, TKU49 and TKU50(T) , were isolated from the oral cavities of chimpanzees (Pan troglodytes). The isolates were all gram-positive, facultative anaerobic cocci that lacked catalase activity. Analysis of partial 16S rRNA gene sequences showed that the most closely related species was Streptococcus infa...

journal_title：Microbiology and immunology

authors： Okamoto M,Imai S,Miyanohara M,Saito W,Momoi Y,Nomura Y,Ikawa T,Ogawa T,Miyabe-Nishiwaki T,Kaneko A,Watanabe A,Watanabe S,Hayashi M,Tomonaga M,Hanada N

更新日期：2015-09-01 00:00:00

abstract：:Borna disease virus (BoDV), a prototype of mammalian bornavirus, is a non-segmented, negative strand RNA virus that often causes severe neurological disorders in infected animals, including horses and sheep. Unique among animal RNA viruses, BoDV transcribes and replicates non-cytopathically in the cell nucleus, leadin...

journal_title：Microbiology and immunology

authors： Fujino K,Yamamoto Y,Daito T,Makino A,Honda T,Tomonaga K

更新日期：2017-09-01 00:00:00

abstract：:The effect of dermonecrotic toxin (DNT), fimbrial hemagglutinin (FHA), K-agglutinogen, lipopolysaccharide (LPS), and pertussigen from Bordetella pertussis on the production of IgE and IgG1 antibodies to hen egg albumin (Ea) was investigated in C57BL/6 mice. The IgE antibody contents were determined by passive cutaneou...

journal_title：Microbiology and immunology

authors： Sekiya K

更新日期：1983-01-01 00:00:00

abstract：:Quantitative PCR is becoming widespread for diagnosing and monitoring post-transplantation diseases associated with EBV and CMV. These assays need to be standardized to manage patients in different facilities. Five independent laboratories in Japan compared home-brew assays and a prototype assay system to establish a ...

journal_title：Microbiology and immunology

authors： Ito Y,Takakura S,Ichiyama S,Ueda M,Ando Y,Matsuda K,Hidaka E,Nakatani K,Nishioka J,Nobori T,Kajiyama N,Kimura H

更新日期：2010-09-01 00:00:00