Variation in virulence of Coxsackie virus B3 in the hearts of mice. I. Comparison of mortality and virus growth in the heart and other organs.

abstract：:The effect of dermonecrotic toxin (DNT), fimbrial hemagglutinin (FHA), K-agglutinogen, lipopolysaccharide (LPS), and pertussigen from Bordetella pertussis on the production of IgE and IgG1 antibodies to hen egg albumin (Ea) was investigated in C57BL/6 mice. The IgE antibody contents were determined by passive cutaneou...

journal_title：Microbiology and immunology

authors： Sekiya K

更新日期：1983-01-01 00:00:00

abstract：:A total of 55 strains of Clostridium sordellii, 21 lethal toxin-positive and 34 lethal toxin-negative, were tested for cytotoxin production in brain heart infusion medium supplemented with 0.2% Na2HPO4 (m-BHI) and cooked-meat-glucose (CMG) medium using baby hamster kidney (BHK-21/WI-2) cells as indicator cells. The m-...

journal_title：Microbiology and immunology

authors： Nakamura S,Tanabe N,Yamakawa K,Nishida S

更新日期：1983-01-01 00:00:00

abstract：:Proteus mirabilis is commonly associated with complicated UTI and expresses several virulence factors, including MR/P fimbriae. In the present study mice were immunised nasally with MrpA, the structural subunit of MR/P, with or without CT as a mucosal adjuvant. The animals were then challenged with P. mirabilis and in...

journal_title：Microbiology and immunology

authors： Scavone P,Rial A,Umpierrez A,Chabalgoity A,Zunino P

更新日期：2009-04-01 00:00:00

abstract：:The activities of a water-soluble peptidoglycan fragment derived from Staphylococcus epidermidis (SEPS) were examined as to their role in proliferation of spleen mononuclear cells (SMNC) from various strains of mice, the production of cytokines in vitro, and the induction of an inflammatory reaction in vivo. The proli...

journal_title：Microbiology and immunology

authors： Onta T,Sashida M,Fujii N,Sugawara S,Rikiishi H,Kumagai K

更新日期：1993-01-01 00:00:00

abstract：:Common EDTA-soluble antigens of Clostridium chauvoei and C. septicum were examined by indirect-immunofluorescence (IFA) and immunoblot analysis. The monoclonal antibodies (mAbs) specific for the 35 kDa antigen of C. chauvoei strain ATCC 10092 were used. These mAbs reacted with all 11 strains, 6 of C. chauvoei and 5 of...

journal_title：Microbiology and immunology

authors： Hamaoka T,Terakado N,Nakamura S

更新日期：1994-01-01 00:00:00

abstract：:Amino acid requirements for the growth of Aedes albopictus, clone C6/36, cells and for the production of dengue (DEN) and Chikungunya (CHIK) viruses were examined by growing the cells or the viruses in media which were deprived of one of the 20 amino acids. Cell growth was markedly inhibited when cystine was omitted f...

journal_title：Microbiology and immunology

authors： Sasao F,Igarashi A,Fukai K

更新日期：1980-01-01 00:00:00

abstract：:Cattle enterotoxemia caused by Clostridium perfringens toxins is a noncontagious, sporadic, and fatal disease characterized by sudden death. Strategies for controlling and preventing cattle enterotoxemia are based on systematic vaccination of herds with toxoids. Because the process of producing conventional clostridia...

journal_title：Microbiology and immunology

authors： Jiang Z,De Y,Chang J,Wang F,Yu L

更新日期：2014-11-01 00:00:00

abstract：:During 1985 to 1990, serum samples were obtained from 229 healthy dogs. The dogs lived in Hokkaido, known to be infested with ticks. An enzyme-linked immunosorbent assay (ELISA) was used to detect IgG and IgM antibodies against Borrelia burgdorferi HO14 and HP3, which were isolated from Ixodes ovatus and I. persulcatu...

journal_title：Microbiology and immunology

authors： Isogai E,Isogai H,Sato N,Yuzawa M,Kawakami M

更新日期：1990-01-01 00:00:00

abstract：:A number of studies have determined the contribution of Th1 and Th2 responses to the protective immunity and pathology of Mycobacterium bovis infection. However, much of that information is derived from experimentally infecting cattle with M. bovis and few data from naturally infected animals are available. The aim of...

journal_title：Microbiology and immunology

authors： Blanco FC,Schierloh P,Bianco MV,Caimi K,Meikle V,Alito AE,Cataldi AA,Sasiain Mdel C,Bigi F

更新日期：2009-08-01 00:00:00

abstract：:Magnaporthe oryzae chrysovirus 1 strain A (MoCV1-A) is the causal agent of growth repression and attenuated virulence (hypovirulence) of the rice blast fungus, M. oryzae. We have previously reported that heterologous expression of MoCV1-A ORF4 in Saccharomyces cerevisiae results in growth defects, a large central vacu...

journal_title：Microbiology and immunology

authors： Urayama S,Fukuhara T,Moriyama H,Toh-E A,Kawamoto S

更新日期：2014-05-01 00:00:00

abstract：:Erythematous delayed reactions without induration, presumably assigned to Jones-Mote type, were characterized by the resistance to treatment with cyclophosphamide (CY) before elicitation or immunization in guinea pigs immunized with BGG in IFA or CFA. CY-treatment before elicitation converted delayed erythematous reac...

journal_title：Microbiology and immunology

authors： Himeno K,Nomoto K,Takeya K

更新日期：1978-01-01 00:00:00

abstract：:The purpose of this study was to sequence the central part of the coding region of the Clostridium tyrobutyricum fiagellin gene to improve the immunoenzymatic counting of cells after milk filtration. The coding region was amplified by PCR, and the amplified products were cloned. A DNA sequence analysis of positive clo...

journal_title：Microbiology and immunology

authors： Arnold F,Bédouet L,Batina P,Robreau G

更新日期：1999-01-01 00:00:00

abstract：:Influenza A virus (IAV) PA-X is a critical ribonuclease protein involved in host cell shutoff but its role in modulating the host immune response to IAV infection remains to be addressed. In this study, host cellular proteins that directly interact with PA-X were screened to investigate the biological function of PA-X...

journal_title：Microbiology and immunology

authors： Li M,Qi W,Chang Q,Chen R,Zhen D,Liao M,Wen J,Deng Y

更新日期：2020-11-26 00:00:00

abstract：:Streptococcus anginosus appears to be able to adhere to cultured epithelial cells or fibronectin and this may be associated with bacterial pathogenicity. In the present study, the molecular characteristics and virulence of the fibronectin-binding protein (FBP), Fbp62, of S. anginosus were investigated in animal models...

journal_title：Microbiology and immunology

authors： Kodama Y,Ishikawa T,Shimoyama Y,Sasaki D,Kimura S,Sasaki M

更新日期：2018-10-01 00:00:00

abstract：:Live attenuated bacteria can be used as a carrier for the delivery of foreign antigens to a host's immune system. The N-terminal domain of SipB, a translocon protein of the type III secretion system of Salmonella enterica serovar Typhimurium, is required for secretion and outer membrane localization. In the present st...

journal_title：Microbiology and immunology

authors： Jang JI,Kim JS,Eom JS,Kim HG,Kim BH,Lim S,Bang IS,Park YK

更新日期：2012-09-01 00:00:00

abstract：:Leptospirosis is a worldwide zoonosis. The importance of urban leptospirosis is recognized in Japan: urban rats carry pathogenic leptospires and people acquire these pathogens through contact with surface water or soil contaminated by the urine of the infected animals. To determine the current Leptospira carriage rate...

journal_title：Microbiology and immunology

authors： Saito M,Villanueva SY,Masuzawa T,Haraguchi Y,Ita S,Miyahara S,Ozuru R,Yamaguchi T,Yoshimura M,Ikejiri M,Aramaki N,Amran MY,Muslich LT,Iida K,Yanagihara Y,Gloriani NG,Yoshida S

更新日期：2015-06-01 00:00:00

abstract：:The gH of CMV is a major target for strain-specific neutralizing antibodies. To verify whether there is a correlation between HLA-DR type and strain-specific antibodies, antibodies against CMV gH in potential donors and recipients for renal transplantation were investigated. Among 471 subjects, 404 (86%) showed reacti...

journal_title：Microbiology and immunology

authors： Ishibashi K,Tokumoto T,Shirakawa H,Hashimoto K,Kushida N,Yanagida T,Shishido K,Aikawa K,Yamaguchi O,Toma H,Tanabe K,Suzutani T

更新日期：2009-07-01 00:00:00

abstract：:Site-specific recombinase is widely applied for the regulation of gene expression because its regulatory action is strict and efficient. However, each system can mediate regulation of only one gene at a time. Here, we demonstrate efficient "sequential" gene regulation using Cre-and FLP-expressing recombinant adenoviru...

journal_title：Microbiology and immunology

authors： Kondo S,Takahashi Y,Shiozawa S,Ichise H,Yoshida N,Kanegae Y,Saito I

更新日期：2006-01-01 00:00:00

abstract：:Immune responses to Helicobacter pylori infection play important roles in gastroduodenal diseases. The contributions of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) to the induction of gastric inflammation and to the protection from H. pylori infection were investigated using TNF-alpha gene...

journal_title：Microbiology and immunology

authors： Yamamoto T,Kita M,Ohno T,Iwakura Y,Sekikawa K,Imanishi J

更新日期：2004-01-01 00:00:00

abstract：:JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system, in immunocompromised patients. Because no drugs have been approved for treating PML, many antiviral agents are currently being investigated for this purpose. The inhibitory effe...

journal_title：Microbiology and immunology

authors： Nukuzuma S,Nakamichi K,Kameoka M,Sugiura S,Nukuzuma C,Tasaki T,Takegami T

更新日期：2016-04-01 00:00:00

abstract：:A polymyxin B (PXB)-resistant mutant of Klebsiella pneumoniae O3 was isolated. Lipopolysaccharide (LPS) extracted from the PXB-resistant isolate bound little PXB, although LPS from the parental strain did. The 31P nuclear magnetic resonance (NMR) spectrum of PXB-resistant type LPS showed that it contained much less of...

journal_title：Microbiology and immunology

authors： Yokochi T,Inoue Y,Jiang GZ,Kato Y,Sugiyama T,Kawai M,Fukada M,Takahashi K

更新日期：1994-01-01 00:00:00

abstract：:An R-form lipopolysaccharide (LPS) extracted from Klebsiella strain LEN-111 (O3-:K1-) by the phenol-chloroform-petroleum ether method was compared with that extracted by the phenol-water method in the ability to form a hexagonal assembly. The LPS which was extracted by the phenol-water method and dialyzed against tap ...

journal_title：Microbiology and immunology

authors： Kato N,Ohta M,Kido N,Ito H,Naito S,Kuno T

更新日期：1985-01-01 00:00:00

abstract：:Structural studies were carried out on an O-antigenic polysaccharide moiety derived from Porphyromonas circumdentaria NCTC 12469, a reference strain of Porphyromonas species. The polysaccharide chain was composed of D-glucose, D-galactose, N-acetyl-D-glucosamine, and N-acetyl-D-galactosamine in a molar ratio of 1:2:1:...

journal_title：Microbiology and immunology

authors： Matsuo K,Isogai E,Araki Y

更新日期：2001-01-01 00:00:00

abstract：:Exocellular proteases produced by Vibrio fluvialis, V. furnissii, V. metschnikovii and V. campbellii were characterized and compared to those of V. mimicus protease (VMP) and V. vulnificus protease (VVP). These proteases possessed both elastolytic and hemagglutinating abilities and were identified, except that of V. m...

journal_title：Microbiology and immunology

authors： Alam M,Miyoshi S,Shinoda S

更新日期：1995-01-01 00:00:00

abstract：:H5N1 and H9N2 are the most important causes of avian influenza in China. Chemokines and cytokines play important roles in inflammatory response that clearly differ between H5N1 and H9N2 infection. To investigate whether chemokines and cytokines are differentially regulated following H5N1 and H9N2 AIVs infection, dynam...

journal_title：Microbiology and immunology

authors： Luo C,Liu J,Qi W,Ren X,Lu R,Liao M,Ning Z

更新日期：2018-05-01 00:00:00

abstract：:The lack of a suitable animal model is a major obstacle to developing anti-HIV-1 vaccines. We successfully generated an SIVmac/HIV-1 chimeric virus (SHIV) (designated as NM-3rN) that contains the HIV-1 env gene and is infectious to macaque monkeys. Challenging the vaccinated macaque monkeys with NM-3rN, we developed a...

journal_title：Microbiology and immunology

authors： Haga T,Kuwata T,Ui M,Igarashi T,Miyazaki Y,Hayami M

更新日期：1998-01-01 00:00:00

abstract：:We have previously shown that immunization of mice with plasmid pMEa synthesizing Japanese encephalitis virus (JEV) envelope protein induced anti-JEV humoral and cellular immune responses. We now show that intra-muscular co-administration of mice with pMEa and pGM-CSF, encoding murine granulocyte-macrophage colony-sti...

journal_title：Microbiology and immunology

authors： Bharati K,Appaiahgari MB,Vrati S

更新日期：2005-01-01 00:00:00

abstract：:Trehalose 6,6'-dimycolate (TDM), or cord factor, is a crucial stimulus of immune responses during Mycobacterium tuberculosis infection. Although TDM has immuno-stimulatory properties, including adjuvant activity and the ability to induce granuloma formation, the mechanisms underlying these remain unknown. We hypothesi...

journal_title：Microbiology and immunology

authors： Lee WB,Yan JJ,Kang JS,Chung S,Kim LK

更新日期：2017-12-01 00:00:00

abstract：:Triosephosphate isomerase (TPI; EC 5. 3. 1. 1) displayed on the cell surface of Staphylococcus aureus acts as an adhesion molecule that binds to the capsule of Cryptococcus neoformans, a fungal pathogen. This study investigated the function of TPI on the cell surface of S. aureus and its interactions with biological s...

journal_title：Microbiology and immunology

authors： Furuya H,Ikeda R

更新日期：2011-12-01 00:00:00

abstract：:A murine monoclonal antibody recognizing (1-->6)-beta-D-glucopyranosyl laminaritriose (G4) was prepared by immunizing BALB/c mice with G4-bovine serum albumin conjugate and fusing the splenocytes with mouse myeloma cells. The monoclonal antibody (IgM) provoked by the cloned cells showed low reactivity with schizophyll...

journal_title：Microbiology and immunology

authors： Hirata A,Komoda M,Itoh W,Tabata K,Sugawara I

更新日期：1995-01-01 00:00:00