Hyper-immunoglobulin G2 production by B cells from patients with localized juvenile periodontitis and its regulation by monocytes.

abstract：:Adoptive immunity is poorly expressed in normal syngeneic mice. This phenomenon was studied by using experimental antituberculosis immunity as a model system representing pure cell-mediated immunity. Expression of adoptive immunity was facilitated by pretreating recipients with sublethal ionizing radiation (500 rads) ...

journal_title：Infection and immunity

authors： Lefford MJ

更新日期：1983-07-01 00:00:00

abstract：:Previous reports from our laboratory have shown that 7 days after infection of C3HeB/FeJ mice with an attenuated strain of Salmonella typhimurium, there is profound suppression of responses to B- and T-cell mitogens and suppression of the capacity of spleen cells to mount a primary, in vitro plaque-forming-cell (PFC) ...

journal_title：Infection and immunity

authors： Huang D,Schwacha MG,Eisenstein TK

更新日期：1996-09-01 00:00:00

abstract：:An impressive change in the epidemiology and severity of invasive group A streptococcal infections occurred in the 1980s, and the incidence of streptococcal toxic shock syndrome cases continues to rise. The reason for the resurgence of severe invasive cases remains a mystery-has there been a change in the pathogen or ...

journal_title：Infection and immunity

authors： Basma H,Norrby-Teglund A,Guedez Y,McGeer A,Low DE,El-Ahmedy O,Schwartz B,Kotb M

更新日期：1999-04-01 00:00:00

abstract：:Immunoglobulin G (IgG)- and IgM-specific antibody titers against Salmonella typhi Ty2 porins have been measured in 30 paired typhoid sera by enzyme-linked immunosorbent assay. These studies have found that IgG serum titers of acute and convalescent sera were 625 and 5,000 times higher, respectively than the control se...

journal_title：Infection and immunity

authors： Calderón I,Lobos SR,Rojas HA,Palomino C,Rodríguez LH,Mora GC

更新日期：1986-04-01 00:00:00

abstract：:It was previously determined that the type II secretion system (T2SS) promotes the ability of Legionella pneumophila to grow in coculture with amoebae. Here, we discerned the stage of intracellular infection that is potentiated by comparing the wild-type and T2SS mutant legionellae for their capacity to parasitize Aca...

journal_title：Infection and immunity

authors： White RC,Truchan HK,Zheng H,Tyson JY,Cianciotto NP

更新日期：2019-10-18 00:00:00

abstract：:The acute phase of Chagas' disease is accompanied by immunosuppression. To explore the underlying mechanism(s), we used an in vitro culture system in which the capacities of activated human peripheral blood mononuclear cells to express interleukin-2 receptors (IL-2R) and proliferate are markedly inhibited in the prese...

journal_title：Infection and immunity

authors： Beltz LA,Kierszenbaum F,Sztein MB

更新日期：1989-08-01 00:00:00

abstract：:Cholera toxin (CT) and the type II heat-labile enterotoxins (HLT) LT-IIa and LT-IIb act as potent systemic and mucosal adjuvants and induce distinct T-helper (Th)-cell cytokine profiles. In the present study, CT and the type II HLT were found to differentially affect cytokine production by anti-CD3-stimulated human pe...

journal_title：Infection and immunity

authors： Martin M,Metzger DJ,Michalek SM,Connell TD,Russell MW

更新日期：2001-07-01 00:00:00

abstract：:Mutation of retS (rtsM) of Pseudomonas aeruginosa strain PA103 reduces its virulence in both ocular and respiratory murine models of infection. In vitro, retS mutants exhibit loss of the ExsA-regulated type III secretion system (TTSS), reduced twitching motility, and a decrease in association with, invasion of, and su...

journal_title：Infection and immunity

authors： Zolfaghar I,Evans DJ,Ronaghi R,Fleiszig SM

更新日期：2006-07-01 00:00:00

abstract：:Investigating the innate immune response mediators released in milk has manifold implications, spanning from elucidation of the role played by mammary epithelial cells (MECs) in fighting microbial infections to the discovery of novel diagnostic markers for monitoring udder health in dairy animals. Here, we investigate...

journal_title：Infection and immunity

authors： Addis MF,Pisanu S,Marogna G,Cubeddu T,Pagnozzi D,Cacciotto C,Campesi F,Schianchi G,Rocca S,Uzzau S

更新日期：2013-09-01 00:00:00

abstract：:Immunization of monkeys with the 82-kDa rhoptry protein (p82) of Plasmodium falciparum can protect them against a lethal blood stage challenge, and monoclonal antibodies to p82 inhibit parasite growth in vitro. The role that a p82-specific immune response might play in human immunity to the parasite is not known. To d...

journal_title：Infection and immunity

authors： Howard RF,Jensen JB,Franklin HL

更新日期：1993-07-01 00:00:00

abstract：:Leishmaniae are protozoans which, depending upon both the host and parasite species, can cause either a healing or nonhealing infection. While C57BL/10 mice are able to heal following infection with Leishmania major, they fail to heal following infection with Leishmania amazonensis. In order to address the role of Th1...

journal_title：Infection and immunity

authors： Afonso LC,Scott P

更新日期：1993-07-01 00:00:00

abstract：:Nerve damage is a clinical hallmark of leprosy and a major source of patient morbidity. We investigated the possibility that human Schwann cells are susceptible to cell death through the activation of Toll-like receptor 2 (TLR2), a pattern recognition receptor of the innate immune system. TLR2 was detected on the surf...

journal_title：Infection and immunity

authors： Oliveira RB,Ochoa MT,Sieling PA,Rea TH,Rambukkana A,Sarno EN,Modlin RL

更新日期：2003-03-01 00:00:00

abstract：:Cord factor (trehalose 6,6'-dimycolate[TDM] ), a mixture of 6,6'-diesters of alpha, alpha-D-trehalose with natural mycolic acids, has been described as having immunoregulatory and antitumor activities in vivo, although the relevant mechanisms of action remain unelucidated. In this work, we measured the effects of TDM ...

journal_title：Infection and immunity

authors： Kierszenbaum F,Zenian A,Wirth JJ

更新日期：1984-02-01 00:00:00

abstract：:On incubation of rabbit polymorphonuclear leukocytes with the S component of staphylococcal leukocidin at 37 degrees C, the 3H-labeled methyl group of S-adenosyl[methyl-3H]methionine was rapidly incorporated into phospholipid. Subsequently, the methylated phosphatidylcholine was degraded by activated phospholipase A2....

journal_title：Infection and immunity

authors： Noda M,Hirayama T,Matsuda F,Kato I

更新日期：1985-10-01 00:00:00

abstract：:Organ cultures of adult hamster trachea were used to evaluate the cytotoxic potential of cell fractions of Mycoplasma pneumoniae. Cytoplasm was essentially devoid of activity, whereas viable cells and membrane preparations, at a level of 25 mug of protein per ml, induced necrosis. Damage, as revealed by light and elec...

journal_title：Infection and immunity

authors： Gabridge MG,Johnson CK,Cameron AM

更新日期：1974-11-01 00:00:00

abstract：:Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does...

journal_title：Infection and immunity

authors： Nair SP,Bischoff M,Senn MM,Berger-Bächi B

更新日期：2003-07-01 00:00:00

abstract：:Human galectin-3 binds to the surface of Trypanosoma cruzi trypomastigotes and human coronary artery smooth muscle (CASM) cells. CASM cells express galectin-3 on their surface and secrete it. Exogenous galectin-3 increased the binding of T. cruzi to CASM cells. Trypanosome binding to CASM cells was enhanced when eithe...

journal_title：Infection and immunity

authors： Kleshchenko YY,Moody TN,Furtak VA,Ochieng J,Lima MF,Villalta F

更新日期：2004-11-01 00:00:00

abstract：:Previous research in this laboratory, using photoactivatable radioiodinated lipopolysaccharide derivatized with sulfosuccinimidyl-2-(p-azidosalicylamide)-1,3'-dithiopropionate (125I-ASD-LPS), has resulted in the identification of a specific LPS receptor with a molecular mass of approximately 73 kDa on murine lymphocyt...

journal_title：Infection and immunity

authors： Halling JL,Hamill DR,Lei MG,Morrison DC

更新日期：1992-03-01 00:00:00

abstract：:Urinary tract infections (UTIs) are among the most common infectious diseases of humans, with Escherichia coli responsible for >80% of all cases. One extreme of UTI is asymptomatic bacteriuria (ABU), which occurs as an asymptomatic carrier state that resembles commensalism. To understand the evolution and molecular me...

journal_title：Infection and immunity

authors： Beatson SA,Ben Zakour NL,Totsika M,Forde BM,Watts RE,Mabbett AN,Szubert JM,Sarkar S,Phan MD,Peters KM,Petty NK,Alikhan NF,Sullivan MJ,Gawthorne JA,Stanton-Cook M,Nhu NT,Chong TM,Yin WF,Chan KG,Hancock V,Ussery DW

更新日期：2015-05-01 00:00:00

abstract：:In this study, we examined the binding of Candida albicans synchronized yeast-phase cells to plastic, immobilized amino acids and bovine serum albumin (BSA) and quantified the binding by using an XTT tetrazolium salt assay and absorbance determination. Our results show that C. albicans binds efficiently and specifical...

journal_title：Infection and immunity

authors： Hawser SP,Islam K

更新日期：1998-01-01 00:00:00

abstract：:Cells of Candida albicans strain WO-1 and related strains switch frequently and reversibly between a white-colony-forming unit (white phase) and a gray-colony-forming unit (opaque phase). Cells in the budding white phase exhibit the usual smooth round phenotype observed in other C. albicans strains, but cells in the b...

journal_title：Infection and immunity

authors： Anderson J,Cundiff L,Schnars B,Gao MX,Mackenzie I,Soll DR

更新日期：1989-02-01 00:00:00

abstract：:The biological response to endotoxin mediated through the Toll-like receptor 4 (TLR4)-MD-2 receptor complex is directly related to lipid A structure or configuration. Endotoxin structure may also influence activation of the MyD88-dependent and -independent signaling pathways of TLR4. To address this possibility, human...

journal_title：Infection and immunity

authors： Zughaier SM,Zimmer SM,Datta A,Carlson RW,Stephens DS

更新日期：2005-05-01 00:00:00

abstract：:Production of interleukin-10 (IL-10) by C57BL/6 mice following infection with Borrelia burgdorferi has been proposed as a mechanism whereby resistance to the development of experimental Lyme arthritis is maintained. In the current study, we sought to determine the role of IL-10 during infection of arthritis- and cardi...

journal_title：Infection and immunity

authors： Brown CR,Lai AY,Callen ST,Blaho VA,Hughes JM,Mitchell WJ

更新日期：2008-12-01 00:00:00

abstract：:The relative roles of serum factors required for opsonization of type XIV Streptococcus pneumoniae were investigated by means of luminol-enhanced chemiluminescence (CL), bactericidal, and immunofluorescence assays employing adult sera containing high (>1,000 ng of antibody nitrogen per ml) or low (<200 ng of antibody ...

journal_title：Infection and immunity

authors： Gardner SE,Anderson DC,Webb BJ,Stitzel AE,Edwards MS,Spitzer RE,Baker CJ

更新日期：1982-03-01 00:00:00

abstract：:Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver lobules during the early phase, and LPS in the late phase caused death in association with pathological changes mimicking he...

journal_title：Infection and immunity

authors： Ikeda N,Mukaida N,Kaneko S,Fujioka N,Su S,Nariuchi H,Unoura M,Harada K,Nakanuma Y,Kobayashi K

更新日期：1995-12-01 00:00:00

abstract：:Menstrually associated toxic shock syndrome (TSS) is attributed primarily to the effects of staphylococcal exotoxin toxic shock syndrome toxin 1 (TSST-1). A region of the 194-amino-acid toxin spanning residues 115 through 144 constitutes a biologically active site. Several point mutations in the TSST-1 gene in that re...

journal_title：Infection and immunity

authors： Bonventre PF,Heeg H,Cullen C,Lian CJ

更新日期：1993-03-01 00:00:00

abstract：:Antigens were extracted from a virulent isolate of Pasteurella multocida (serotype 3, 12, 15:D) with potassium thiocyanate, and a vaccine was prepared. Pasteurella-free rabbits were vaccinated intranasally and intraconjuctivally twice with a 2-week interval and challenged intranasally with the homologous P. multocida ...

journal_title：Infection and immunity

authors： Ringler DH,Peter GK,Chrisp CE,Keren DF

更新日期：1985-09-01 00:00:00

abstract：:Oligosaccharides (OSs) related to the pneumococcal type 14 capsular polysaccharide (Pn14PS) were studied for their ability to inhibit the binding between anti-PS14 antisera and native PS14. A synthetic tetrasaccharide corresponding to the repeating unit of the Pn14PS, a hexasaccharide mimic, and an octasaccharide frag...

journal_title：Infection and immunity

authors： Mawas F,Niggemann J,Jones C,Corbel MJ,Kamerling JP,Vliegenthart JF

更新日期：2002-09-01 00:00:00

abstract：:Antiserum and purified immunoglobulin directed against Mycoplasma pneumoniae membrane protein P1 were examined for their influence on mycoplasma viability, metabolism, and cytadsorption. Anti-P1 immunoglobulin inhibited adherence of M. pneumoniae to hamster tracheal rings in vitro by up to 80% and inhibited hemadsorpt...

journal_title：Infection and immunity

authors： Krause DC,Baseman JB

更新日期：1983-03-01 00:00:00

abstract：:We report the immunizing capacity of Salmonella enteritidis AL1192, a strain that has been cured of a 36-megadalton plasmid, to protect ddY mice against subsequent challenge with virulent salmonellas. This strain, which was given subcutaneously at a dose of 10(6) organisms, provided significant protection against oral...

journal_title：Infection and immunity

authors： Nakamura M,Sato S,Ohya T,Suzuki S,Ikeda S,Koeda T

更新日期：1985-11-01 00:00:00