Down-regulation of L-selectin surface expression by various leukocyte isolation procedures.

abstract：:Sjögren's syndrome is characterized by dryness of the eyes and the mouth due to mononuclear cell infiltration of the lacrimal and salivary glands. The aetiology is unknown but autoimmunity is considered to play a significant role in the pathogenesis. Recent studies have focused on the fact that tear and salivary flow ...

journal_title：Scandinavian journal of immunology

authors： Humphreys-Beher MG,Brayer J,Yamachika S,Peck AB,Jonsson R

更新日期：1999-01-01 00:00:00

abstract：:Severe hypercholesterolaemia is associated with decreased levels of immunoglobulin G2a (IgG2a) antibodies [T-helper 1 (Th1) response] to modified malondialdehyde-modified low-density lipoprotein (MDA-LDL) and increased levels of Th2-dependent IgG1 antibodies in apolipoprotein E-deficient (apoE(-/-)) mice. To investiga...

journal_title：Scandinavian journal of immunology

authors： Robertson AK,Zhou X,Strandvik B,Hansson GK

更新日期：2004-03-01 00:00:00

abstract：:Fenugreek is a legume mostly used as a spice in Indian-style cooking. Although it has been used since ancient times, its allergenicity has only been reported in the last two decades. It poses special problems as an emerging and often hidden allergen. Fenugreek exposure may have serious implications also for individual...

journal_title：Scandinavian journal of immunology

authors： Vinje NE,Namork E,Løvik M

更新日期：2011-10-01 00:00:00

abstract：:Normal mouse spleen cells were cultured in different conditioned media (CM). Mixed lymphocyte culture supernatant (MLC SN) was shown to promote the proliferation of cytotoxic, Thy-1+, Lyt-1+, Lyt-2+, asialo-GM-1+, weakly adherent cells with numerous vacuoles and lysosome-like cytoplasmic granules. In contrast, the Con...

journal_title：Scandinavian journal of immunology

authors： Courtoy R,Schaaf-Lafontaine N,Degiovanni G,Boniver J

更新日期：1983-08-01 00:00:00

abstract：:Coeliac disease (CD) is a very common food-sensitive enteropathy, which is triggered by gluten ingestion and is mediated by CD4(+) T cells. In addition, alterations in the intestinal microbiota that is normally involved in the homeostasis of GALT (gut-associated lymphoid tissue) seem to play a role in CD. In accordanc...

journal_title：Scandinavian journal of immunology

authors： D'Arienzo R,Stefanile R,Maurano F,Mazzarella G,Ricca E,Troncone R,Auricchio S,Rossi M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency. Although most people with selective IgAD (sIgAD) are asymptomatic, many patients often suffer from recurrent respiratory infections and different allergic disorders. Our aim was to investigate connection between subtypes of sIgAD...

journal_title：Scandinavian journal of immunology

authors： Živković J,Lipej M,Banić I,Bulat Lokas S,Nogalo B,Lulić Jurjević R,Turkalj M

更新日期：2019-12-01 00:00:00

abstract：:Immunoglobulin D (IgD) is the least studied of immunoglobulin classes. This study sought to investigate the potential relationship between demographic, metabolic, lifestyle and immunological factors, and serum IgD concentrations in a general adult population. We measured serum IgD concentrations by means of a commerci...

journal_title：Scandinavian journal of immunology

authors： Carballo I,Rabuñal N,Alvela L,Pérez LF,Vidal C,Alonso M,Sopeña B,Gude F,Gonzalez-Quintela A

更新日期：2017-04-01 00:00:00

abstract：:To evaluate the level of lymphocyte activation in reactive and rheumatoid arthritis, density gradient-isolated, synovial fluid mononuclear cells were stained with a panel of antisera directed at lymphocyte activation markers using an avidin-biotin-peroxidase complex (ABC) method. More specifically, we studied the expr...

journal_title：Scandinavian journal of immunology

authors： Konttinen YT,Nordström D,Bergroth V,Leirisalo-Repo M,Skrifvars B

更新日期：1986-06-01 00:00:00

abstract：:Natural killer (NK) cells form part of the vertebrate defence against viruses and tumours, but show only limited specificity. The molecule(s) recognized by NK cells on target cells are at present unknown. Major histocompatibility complex (MHC) class I antigen concentration on target cells is inversely correlated with ...

journal_title：Scandinavian journal of immunology

authors： Müllbacher A,King NJ

更新日期：1989-07-01 00:00:00

abstract：:To determine whether psoriatic keratinocytes differ from normal keratinocytes in their response to gamma interferon, epidermal cell suspensions from normal and from lesional and uninvolved psoriatic skin were cultured in the presence of gamma interferon and the induction of HLA-DR expression and inhibition of cell gro...

journal_title：Scandinavian journal of immunology

authors： Baker BS,Powles AV,Valdimarsson H,Fry L

更新日期：1988-12-01 00:00:00

abstract：:The ability of 17 monoclonal antibodies (MoAb) against measles virus haemagglutinin (MV-H) to bind to 10 selected MV-H-specific synthetic peptides was tested in an enzyme immunoassay (EIA). Three peptides representing residues 126-135 (close to the NH2 terminus), 309-318 (middle), and 587-596 (C-terminal) reacted with...

journal_title：Scandinavian journal of immunology

authors： Mäkelä MJ,Salmi AA,Norrby E,Wild TF

更新日期：1989-08-01 00:00:00

abstract：:Cockroaches have been identified as one of the major indoor allergens inducing perennial rhinitis and asthma. Per a 1s are a group of the major allergens from American cockroach. Although Per a 1s are major allergens from American cockroach, factors contributing to the allergenicity of Per a 1s are still poorly define...

journal_title：Scandinavian journal of immunology

authors： He S,Zhang Z,Zhang H,Wei J,Yang L,Yang H,Sun W,Zeng X,Yang P

更新日期：2011-09-01 00:00:00

abstract：:We have studied the interaction of mitogenic lectins such as phytohaemagglutinin (PHA) and concanavalin A (Con A) with both surface molecules which, by the use of monoclonal antibodies, are known to trigger T-cell mitogenesis. Monoclonal antibodies recognizing the T-lymphocyte receptor for antigen (Ti) and/or its asso...

journal_title：Scandinavian journal of immunology

authors： Leca G,Boumsell L,Fabbi M,Reinherz EL,Kanellopoulos JM

更新日期：1986-05-01 00:00:00

abstract：:Twenty-eight children infected with Schistosoma haematobium and S. mansoni were tested for natural killer (NK) cell activity in vitro using the myeloid/erythroid cell line K562 as target. In addition, the frequency of large granular lymphocytes (LGL) and the number of HNK-1+ lymphocytes were examined in peripheral blo...

journal_title：Scandinavian journal of immunology

authors： Gastl GA,Feldmeier H,Kortmann C,Daffalla AA,Peter HH

更新日期：1986-03-01 00:00:00

abstract：:In murine schistosomiasis mansoni the worm egg-induced granulomatous inflammation is bi-phasic: an initial Th1 type is subsequently switched to a Th2 type response. Analysis of the cellular, molecular base of the Th1-associated response (5-6 weeks post infection) revealed mRNA messages for interleukin (IL)-12 p40, IL-...

journal_title：Scandinavian journal of immunology

authors： Todt JC,Whitfield JR,Ivard SR,Boros DL

更新日期：2000-10-01 00:00:00

abstract：:After 3-5 days of in vitro culture, peritoneal cells from untreated C3H mice produce autoantibodies specific for autoantigens in the membranes of mouse erythrocytes. The autoantigens are exposed in vitro by treating mouse erythrocytes with the proteolytic enzyme bromelain. Limiting-dilution cell culture techniques wer...

journal_title：Scandinavian journal of immunology

authors： Cox KO,Daenke S,Samcewicz B

更新日期：1984-12-01 00:00:00

abstract：:The relationship between the so-called natural interferon-alpha (IFN-alpha) producing cell (IPC), stimulated to produce IFN-alpha by herpes simplex virus type 1 (HSV), and of dendritic cells (DC) in peripheral blood leucocytes was investigated. The simultaneous expression of cell surface antigens and intracellular IFN...

journal_title：Scandinavian journal of immunology

authors： Svensson H,Johannisson A,Nikkilä T,Alm GV,Cederblad B

更新日期：1996-08-01 00:00:00

abstract：:Allograft rejection involves T-cell activation, requiring T-cell receptor interactions with major histocompatibility complex (MHC) molecules and costimulatory signals delivered through the B7-CD28 pathway. We evaluated the effect of blocking this pathway on graft rejection and survival, in a rat experimental model of ...

journal_title：Scandinavian journal of immunology

authors： Kurlberg G,Haglind E,Schön K,Törnqvist H,Lycke N

更新日期：2000-03-01 00:00:00

abstract：:World Health Organisation recommends the practice of BCG vaccination at birth in countries which have a high incidence of tuberculosis and/or high leprosy burden. The BCG vaccination is considered safe for a competent immune system. However, in children with weakened immune systems cause of which can be primary or sec...

journal_title：Scandinavian journal of immunology

authors： Yadav RM,Dalvi A,Gupta M,Bargir UA,Shabrish S,Aluri J,Kulkarni M,Hule G,Kambli P,Setia P,Jodhawat N,Taur P,Desai M,Madkaikar MR

更新日期：2020-12-16 00:00:00

abstract：:Myeloid dendritic cells (MyDCs), prime stimulators of antigen-specific immunity, can serve as one of the major reservoirs for human immunodeficiency virus type-1 (HIV-1). Utilizing mature monocyte-derived MyDCs generated with granulocyte/macrophage colony-stimulating factor, interleukin-4, and tumour necrosis factor-a...

journal_title：Scandinavian journal of immunology

authors： Gieseler RK,Marquitan G,Hahn MJ,Perdon LA,Driessen WH,Sullivan SM,Scolaro MJ

更新日期：2004-05-01 00:00:00

abstract：:Interleukin-1 (IL-1) production by the human monocyte-like cloned cell line CM-SM has been investigated as a function of the state of cell differentiation. CM-SM cells were induced to differentiate along the monocyte-macrophage lineage by bacterial lipopolysaccharides (LPS) or by 12-O-tetradecanoyl-phorbol-13-acetate ...

journal_title：Scandinavian journal of immunology

authors： Revoltella RP,Butler RH,Musiani P,Piantelli M,Ranelletti FO

更新日期：1985-01-01 00:00:00

abstract：:Interactions between homing receptors on circulating leucocytes and endothelial addressins regulate tissue-specific cellular extravasation. Although integrin alpha 4 beta 7 appears to be the main receptor for gut-homing T lymphocytes, less is known about molecules mediating mucosal B cell homing. Expression of integri...

journal_title：Scandinavian journal of immunology

authors： Farstad IN,Halstensen TS,Lazarovits AI,Norstein J,Fausa O,Brandtzaeg P

更新日期：1995-12-01 00:00:00

abstract：:Human peripheral blood monocyte subsets with and without Fc receptor for human IgG are known to suppress (FcR+) and enhance (FcR-) pokeweed mitogen-induced polyclonal immunoglobulin synthesis in vitro. The ability of these subsets to modulate immunoglobulin production in the presence or absence of OKT8+ T cells and un...

journal_title：Scandinavian journal of immunology

authors： Pryjma J,Flad HD,Gruber M,Ernst M

更新日期：1986-07-01 00:00:00

abstract：:The avidity of breast milk IgA antibody was studied with the aid of thiocyanate elution of antibody from solid-phase bound E.coli polysaccharides and diphtheria toxoid. The relative avidity index for each sample was determined by the molarity of thiocyanate required to elute 50% of the bound IgA antibody under conditi...

journal_title：Scandinavian journal of immunology

authors： Roberton DM,Carlsson B,Coffman K,Hahn-Zoric M,Jalil F,Jones C,Hanson LA

更新日期：1988-12-01 00:00:00

abstract：:Our data on peripheral blood T cells from Motor neuron disease (MND) patients indicate major immunological disturbances linked to this disease. Both CD4+ and CD8+ T-cell subsets display an increased fraction of cells showing activation markers compared to controls, indicating an unusually high level of activity in bot...

journal_title：Scandinavian journal of immunology

authors： Katchar K,Osorio L,Conradi S,Wigzell H,Gigliotti D

更新日期：2001-07-01 00:00:00

abstract：:Tuberculosis (TB) is an important infectious disease worldwide. Currently, Bacillus Calmette-Guérin (BCG) remains the only TB vaccine licensed for human use. This TB vaccine is effective in protecting children against severe military TB but offers variable protective efficacy in adults. Therefore, new vaccines against...

journal_title：Scandinavian journal of immunology

authors： Méndez-Samperio P

更新日期：2018-10-01 00:00:00

abstract：:The major subunit protein of amyloid fibrils (758) isolated from a patient with systemic amyloidosis and studied by N-terminal amino acid sequence analysis was found to be almost identical to the sequence of a V lambda IV Bence-Jones protein and a previously described A lambda IV amyloid protein. The two A lambda IV a...

journal_title：Scandinavian journal of immunology

authors： Natvig JB,Westermark P,Sletten K,Husby G,Michaelsen T

更新日期：1981-07-01 00:00:00

abstract：:Autologous and allogeneic mixed lymphocyte cultures (AMC and MLC) were assayed for blastogenesis, generation of cytotoxic potential, and the effect of interferon (IFN-alpha) on these features. The cells of the mixed cultures lysed K562, Daudi, and autologous and allogeneic phytohaemagglutinin blasts. Stimulator-specif...

journal_title：Scandinavian journal of immunology

authors： Argov S,Klein E

更新日期：1983-03-01 00:00:00

abstract：:Normal human glomerular basement membrane (H-GBM) was solubilized by collagenase and subjected to crossed immunoelectrophoresis with rabbit antibodies against H-GBM. Seven precipitates appeared with the mobility of alpha, beta, and gamma globulins. Only two of these precipitates might be specific for GBM, since the ot...

journal_title：Scandinavian journal of immunology

authors： Henriksen K,Jensen H

更新日期：1975-01-01 00:00:00

abstract：:The results reported here suggest that there exist two T-cell-mitogenic responsive populations in the spleen--one that is responsive to concanavalin A (Con A) and a second one that is responsive to Con A and phytohemagglutinin (PHA). Using an in vitro restimulation system, we have found that a primary in vivo activati...

journal_title：Scandinavian journal of immunology

authors： Waterfield JD,Ekstedt RD,Möller G

更新日期：1977-01-01 00:00:00