Further structural and antigenic studies of light-chain amyloid proteins.

abstract：:Twenty-eight children infected with Schistosoma haematobium and S. mansoni were tested for natural killer (NK) cell activity in vitro using the myeloid/erythroid cell line K562 as target. In addition, the frequency of large granular lymphocytes (LGL) and the number of HNK-1+ lymphocytes were examined in peripheral blo...

journal_title：Scandinavian journal of immunology

authors： Gastl GA,Feldmeier H,Kortmann C,Daffalla AA,Peter HH

更新日期：1986-03-01 00:00:00

abstract：:Fresh human T lymphocytes from the blood of healthy individuals exhibited few motile forms, i.e. nonspherical shape and lamellar surface activity, when allowed to settle on a plastic surface. This poor motility of 'normal' blood T lymphocytes is most likely physiological, since under the same conditions more than 75% ...

journal_title：Scandinavian journal of immunology

authors： Sundqvist KG,Otteskog P,Mellstedt H

更新日期：1986-06-01 00:00:00

abstract：:The aim of this study was to evaluate possible changes in the circulating levels of interferon (IFN)-gamma, interleukin (IL)-4 and transforming growth factor (TGF)-beta in association with the autoimmune process leading to type 1 diabetes. Expression levels of mRNAs specific for each cytokine were determined in periph...

journal_title：Scandinavian journal of immunology

authors： Halminen M,Simell O,Knip M,Ilonen J

更新日期：2001-05-01 00:00:00

abstract：:Physiological ageing is accompanied by decline in immune system function and immune alteration during ageing increases susceptibility to infections. We retrospectively analysed the data for complete blood count (CBC) and lymphocyte subsets from infant to elderly age groups to determine changes during ageing. Data from...

journal_title：Scandinavian journal of immunology

authors： Valiathan R,Ashman M,Asthana D

更新日期：2016-04-01 00:00:00

abstract：:Cellular immune responses to recombinant (r) Sm14 were examined in chronic, treated patients and uninfected individuals living in an endemic area for schistosomiasis. The lymphocyte proliferative responses and cytokine profile to this antigen were evaluated. Peripheral blood mononuclear cells (PBMC) of all groups stud...

journal_title：Scandinavian journal of immunology

authors： Brito CF,Caldas IR,Coura Filho P,Correa-Oliveira R,Oliveira SC

更新日期：2000-06-01 00:00:00

abstract：:Anti-inflammation strategy is one of the proposed therapeutic approaches to hepatic fibrosis. T helper (Th) 17 cells, which play a detrimental role in experimental murine models of inflammatory diseases, have been demonstrated to participate in the pathogenesis of liver damage. The inhibitory effect of halofuginone (H...

journal_title：Scandinavian journal of immunology

authors： Liang J,Zhang B,Shen RW,Liu JB,Gao MH,Geng X,Li Y,Li YY,Zhang W

更新日期：2014-03-01 00:00:00

abstract：:Immunotherapy using dendritic cells (DC) has shown promising results. However, the use of an appropriate DC population is critical for the outcome of this treatment, and the search for an optimal DC subset is still ongoing. The DC used in immunotherapy today are usually matured with a cytokine cocktail consisting of T...

journal_title：Scandinavian journal of immunology

authors： Karlsen M,Hovden AO,Vogelsang P,Tysnes BB,Appel S

更新日期：2011-08-01 00:00:00

abstract：:The majority of patients with myasthenia gravis were shown to have T and B cells specific for a beta-bungarotoxin binding protein, presynaptic membrane receptor (PsmR). Such autoreactive T cells may be subdivided into different subsets according to the pattern of cytokine production. In this study the authors examined...

journal_title：Scandinavian journal of immunology

authors： Yi Q,Pirskanen R,Lefvert AK

更新日期：1996-01-01 00:00:00

abstract：:The immune system of a healthy individual responds vigorously to foreign microbial antigens. However, all potentially immunogenic regions (determinants) within an antigen are not functionally of equal relevance in mediating host immunity against the pathogen. Moreover, some of these antigenic determinants are well pro...

journal_title：Scandinavian journal of immunology

authors： Sinha P,Snyder JA,Kim EY,Moudgil KD

更新日期：2007-02-01 00:00:00

abstract：:Serum and salivary concentrations of immunoglobulin A1 (IgA1) and IgA2 were studied in 105 Icelandic children aged 0-12 years. Serum concentrations of both IgA1 and IgA2 increased slightly (P < 0.001) during childhood. The salivary IgA1/IgA2 ratio tended to decrease during the same period; this trend is less apparent ...

journal_title：Scandinavian journal of immunology

authors： Weemaes C,Klasen I,Göertz J,Beldhuis-Valkis M,Olafsson O,Haraldsson A

更新日期：2003-12-01 00:00:00

abstract：:Tumour necrosis factor-α-induced protein-8 like-2 (TIPE2) is a newly identified immune negative regulator. The abnormal expression of TIPE2 has been found in several human inflammatory diseases. However, the expression level and clinical significance of TIPE2 in childhood asthma remain unclear. In this study, we detec...

journal_title：Scandinavian journal of immunology

authors： Ma Y,Liu X,Wei Z,Wang X,Wang Z,Zhong W,Li Y,Zhu F,Guo C,Zhang L,Wang X

更新日期：2013-12-01 00:00:00

abstract：:Using ELISA, we have quantified the levels of IL-2 and IFN-gamma in the oral mucosa, ear skin and regional and distant lymph nodes in an experimental murine model of contact sensitivity (CS), induced by the hapten oxazolone (OXA). Compared to normal conditions, the levels of IL-2 peaked early (4-6 h) after hapten expo...

journal_title：Scandinavian journal of immunology

authors： Ahlfors EE,Lyberg T

更新日期：2010-07-01 00:00:00

abstract：:T cells from immune guinea-pigs produce clusters in vitro with macrophages pulsed with soluble protein antigens. The formation of clusters is antigen-specific. Time-lapse cinephotomicrography was used to study the sequence of events leading to cluster formation and the kinetics of already formed clusters. The central ...

journal_title：Scandinavian journal of immunology

authors： Petri J,Braendstrup O,Werdelin O

更新日期：1979-01-01 00:00:00

abstract：:Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo-embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occurrence of the arrh...

journal_title：Scandinavian journal of immunology

authors： Lappegård KT,Hovland A,Pop GA,Mollnes TE

更新日期：2013-08-01 00:00:00

abstract：:Tuberculosis (TB) is an important infectious disease worldwide. Currently, Bacillus Calmette-Guérin (BCG) remains the only TB vaccine licensed for human use. This TB vaccine is effective in protecting children against severe military TB but offers variable protective efficacy in adults. Therefore, new vaccines against...

journal_title：Scandinavian journal of immunology

authors： Méndez-Samperio P

更新日期：2018-10-01 00:00:00

abstract：:The binding of a 34-kDa (mol. wt.) acylpoly(1,3)galactoside (APG) extracted from a membrane proteoglycan of Klebsiella pneumoniae to human blood leucocytes was investigated. APG is made of a long poly(1,3)galactose chain, a core-like region and a lipid moiety which comprises two glucosamine residues bound to a phospha...

journal_title：Scandinavian journal of immunology

authors： Hmama Z,Kouassi E,Panaye G,Delassan S,Normier G,Binz H,Revillard JP

更新日期：1992-07-01 00:00:00

abstract：:Rat popliteal and the iliac lymph nodes were examined after foot-pad injections of colloidal carbon and ferritin-tetramethylrhodamine isothiocyanate. Carbon rapidly entered medullary sinuses, but the entry of carbon into the interstitium was prohibited by avid phagocytosis, by sinus macrophages and by the lymphoendoth...

journal_title：Scandinavian journal of immunology

authors： Fossum S

更新日期：1980-01-01 00:00:00

abstract：:The in vitro anti-trinitrophenyl (TNP) response induced by TNP-lipopolysaccharide (TNP-LPs) in mouse spleen cells was eliminated by passage through Sephadex G10 columns. Conditioned medium obtained from peritoneal macrophages restored the response, indicating the supportive role of such cells in the response. Converse...

journal_title：Scandinavian journal of immunology

authors： Martinez-Alonso C,Bernabe RR,Diaz-Espada F

更新日期：1980-01-01 00:00:00

abstract：:We have examined the frequencies of T gamma delta cells in blood, synovial fluids, and synovial membranes of patients with rheumatoid arthritis (RA) and in blood from age-matched controls. Immunocytochemical and immunohistochemical techniques were used with monoclonal antibodies BB3 and A13 to define a major and minor...

journal_title：Scandinavian journal of immunology

authors： Smith MD,Bröker B,Moretta L,Ciccone E,Grossi CE,Edwards JC,Yüksel F,Colaco B,Worman C,Mackenzie L

更新日期：1990-12-01 00:00:00

abstract：:Peripheral CD4 T-cell depletion has been observed in human immunodeficiency virus (HIV)-negative patients with pulmonary tuberculosis (TB). To investigate more accurately this alteration, we studied peripheral blood CD45RA(+) and CD29(high) CD4 subsets in 79 TB patients with (HIV(+)TB(+)) or without (HIV(-)TB(+)) HIV ...

journal_title：Scandinavian journal of immunology

authors： Diagbouga S,Chiron JP,Sanou O,Ledru E

更新日期：2001-01-01 00:00:00

abstract：:T helper 17 (TH17) cells have well-described roles in autoimmune diseases. The immune modulations of development and function of TH17 have become a key issue. In this review, we summarize the recent findings regarding the direct and indirect signalling regulatory mechanisms of TH17 cells in the general mouse model of ...

journal_title：Scandinavian journal of immunology

authors： Bi Y,Yang R

更新日期：2012-06-01 00:00:00

abstract：:To determine whether the genetic background of the insulin-producing beta cells of the pancreas contributes to autoimmune diabetes susceptibility, we have used a model of the disease based on transferring spleen cells from nonobese diabetic (NOD) <--> C57BL/6 (B6) embryo aggregation (EA) chimeras into B6 and NOD irrad...

journal_title：Scandinavian journal of immunology

authors： Colucci F,Bergman ML,Lejon K,Holmberg D

更新日期：1998-12-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by susceptibility to bacterial and fungal infections resulting from the inadequacy of phagocytic leucocytes to produce reactive oxygen radicals. CGD is a genetically heterogeneous disease with an X-linked recessive (XR-CGD) form caused by ...

journal_title：Scandinavian journal of immunology

authors： Kutukculer N,Aykut A,Karaca NE,Durmaz A,Aksu G,Genel F,Pariltay E,Cogulu Ö,Azarsız E

更新日期：2019-02-01 00:00:00

abstract：:Intradermal inoculation of mice with naked plasmid DNA encoding the regulatory HIV-1 Nef protein was shown to induce Nef-specific T and B cell responses. Co-inoculation with an expression vector encoding murine granulocyte-macrophage colony-stimulating factor (GM-CSF), a cytokine known to facilitate the induction of p...

journal_title：Scandinavian journal of immunology

authors： Svanholm C,Löwenadler B,Wigzell H

更新日期：1997-09-01 00:00:00

abstract：:The reactivity of rabbit anti-HLA-DR antigen antibodies with cells in normal and rheumatoid synovial tissue was investigated by indirect immunofluorescence on frozen sections of tissue. The antibodies reacted with a significant proportion of the synovial lining cells of both normal and rheumatoid synovial tissue, with...

journal_title：Scandinavian journal of immunology

authors： Klareskog L,Forsum U,Malmnäs Tjernlund UK,Kabelitz D,Wigren A

更新日期：1981-08-01 00:00:00

abstract：:Age and gender-related variability of main lymphocyte subsets (T, B and NK cell absolute counts and percentages from Ly; T4, T8 and DN cell absolute counts and percentages from lymphocytes and from T cells; T4:T8 and T:B ratios) was studied in a large cohort of pediatric patients (2 days - 17 years) at yearly interval...

journal_title：Scandinavian journal of immunology

authors： Nikulshin S,Kundzina L,Tolstikova I,Gravele D,Prokofjeva T,Gardovska D

更新日期：2018-06-23 00:00:00

abstract：:This paper describes the generation, detection and characterization of cytotoxic t lymphocyte activity in vitro and the application of this assay system to various immunological problems. ...

journal_title：Scandinavian journal of immunology

authors： Engers HD,Macdonald HR

更新日期：1976-06-01 00:00:00

abstract：:An idiotypic network model of AIDS pathogenesis is described in which the T cell receptor plays a role both in infection and as a target of autoimmunity. This is an extension of a previously published autoimmunity model, and provides explanations for several otherwise puzzling aspects of AIDS pathogenesis. In the mode...

journal_title：Scandinavian journal of immunology

authors： Hoffmann GW

更新日期：1995-04-01 00:00:00

abstract：:Myeloid dendritic cells (MyDCs), prime stimulators of antigen-specific immunity, can serve as one of the major reservoirs for human immunodeficiency virus type-1 (HIV-1). Utilizing mature monocyte-derived MyDCs generated with granulocyte/macrophage colony-stimulating factor, interleukin-4, and tumour necrosis factor-a...

journal_title：Scandinavian journal of immunology

authors： Gieseler RK,Marquitan G,Hahn MJ,Perdon LA,Driessen WH,Sullivan SM,Scolaro MJ

更新日期：2004-05-01 00:00:00

abstract：:γδ T cells are characterized by recognizing conserved endogenous and stress-induced antigens without antigen presentation. It has been show that γδ T cells play an important role in anti-tumour/microbe responses, but their function in autoimmune diseases is yet not clear. Here, we reported the quantity and phenotype o...

journal_title：Scandinavian journal of immunology

authors： Wang L,Kang N,Zhou J,Guo Y,Zhang X,Cui L,Ba D,He W

更新日期：2012-07-01 00:00:00