The effect of antifibrotic drug halofugine on Th17 cells in concanavalin A-induced liver fibrosis.

abstract：:The mixed lymphocyte culture (MLC) response of lymphocytes from CBA mice against C3H cells was studied after injection of spleen cells from C3H mice or C3H hybrids. Intravenous infusion of C3H cells resulted in a strongly suppressed specific MLC response, but this was not the case when cells from H-2-incompatible hybr...

journal_title：Scandinavian journal of immunology

authors： Lilliehöök B,Jacobsson H,Blomgren H

更新日期：1975-01-01 00:00:00

abstract：:A serum amyloid A (SAA) clone was isolated from a Tammar wallaby cDNA library, the most distantly related mammalian species for which an SAA has been described to date. The clone predicts a premolecule of 127 amino acids with good homology to other mammalian SAAs, and consists of an 18 residue leader peptide and a mat...

journal_title：Scandinavian journal of immunology

authors： Uhlar CM,Black IL,Shields DC,Brack CM,Schreiber G,Whitehead AS

更新日期：1996-03-01 00:00:00

abstract：:After intravenous injection of 10(5) purified, lymph node (LN)-derived dm2 (H-2d/Ld-) CD4+ T cells into young C.B-17 scid/scid (severe combined immunodeficiency, SCID) mice (H-2d/Ld+), the transplanted Ld-T cells show a selective pattern of engraftment: they repopulate the spleen, the lamina propria of the small intes...

journal_title：Scandinavian journal of immunology

authors： Rudolphi A,Enssle KH,Claesson MH,Reimann J

更新日期：1993-07-01 00:00:00

abstract：:We have examined the frequencies of T gamma delta cells in blood, synovial fluids, and synovial membranes of patients with rheumatoid arthritis (RA) and in blood from age-matched controls. Immunocytochemical and immunohistochemical techniques were used with monoclonal antibodies BB3 and A13 to define a major and minor...

journal_title：Scandinavian journal of immunology

authors： Smith MD,Bröker B,Moretta L,Ciccone E,Grossi CE,Edwards JC,Yüksel F,Colaco B,Worman C,Mackenzie L

更新日期：1990-12-01 00:00:00

abstract：:Immature monocytes residing in the spleens of newborn mice less than 6-7 days of age are known to suppress T-dependent and T-independent immune responses in vitro and in vivo. Suppression is mediated in part through products secreted by the newborn monocytes. In the present study, we have identified 3 monokines secret...

journal_title：Scandinavian journal of immunology

authors： Jadus MR,Peck AB

更新日期：1986-01-01 00:00:00

abstract：:Serum and salivary concentrations of immunoglobulin A1 (IgA1) and IgA2 were studied in 105 Icelandic children aged 0-12 years. Serum concentrations of both IgA1 and IgA2 increased slightly (P < 0.001) during childhood. The salivary IgA1/IgA2 ratio tended to decrease during the same period; this trend is less apparent ...

journal_title：Scandinavian journal of immunology

authors： Weemaes C,Klasen I,Göertz J,Beldhuis-Valkis M,Olafsson O,Haraldsson A

更新日期：2003-12-01 00:00:00

abstract：:Previously reported experiments suggested that an esterase or a protease, or both, might participate in the expression of human leukocyte migration inhibitory factor (LIF). To clarify this further, a wide variety of simple ester were tested for the ability to protect LIF against inactivation by the serine esterase inh...

journal_title：Scandinavian journal of immunology

authors： Bendtzen K

更新日期：1977-01-01 00:00:00

abstract：:Development of type-II collagen (CII)-induced arthritis (CIA) is dependent on a T-cell mediated activation of autoreactive B cells. However, it is still unclear if B cells can present CII to T cells. To investigate the role of B cells as antigen-presenting cells (APCs) for CII, we purified B cells from lymph nodes of ...

journal_title：Scandinavian journal of immunology

authors： Holmdahl M,Vestberg M,Holmdahl R

更新日期：2002-04-01 00:00:00

abstract：:Congenital heart block (CHB) is a conduction abnormality that affects hearts of foetuses and/or newborn to mothers with autoantibodies reactive with the intracellular soluble ribonucleoproteins 48-kD La, 52-kD Ro and 60-kD Ro. CHB carries substantial mortality and morbidity, with more than 60% of affected children req...

journal_title：Scandinavian journal of immunology

authors： Karnabi E,Boutjdir M

更新日期：2010-09-01 00:00:00

abstract：:During B-cell development in the avian bursa of Fabricius most of the developing B cells die by apoptosis and only a minority survive to emigrate into the periphery. Recently, it has been shown that when developing bursal cells become mature and ready to migrate they start to express chL12 antigen. The expression of t...

journal_title：Scandinavian journal of immunology

authors： Lampisuo M,Arstila TP,Liippo J,Lassila O

更新日期：1998-03-01 00:00:00

abstract：:The immunological effector mechanism responsible for the elimination of virus in murine acute non-fatal extracranial lymphocytic choriomeningitis virus infection was studied. In this infection virus clearance is generally regarded as the result of a direct action of virus-specific cytotoxic T cells (Tc cells) on virus...

journal_title：Scandinavian journal of immunology

authors： Thomsen AR,Volkert M,Bro-Jørgensen K

更新日期：1983-06-01 00:00:00

abstract：:The lymphocyte subsets in the bronchoalveolar lavage fluid (BALF) and the peripheral blood of 25 healthy volunteers were examined by analysis with a fluorescence-activated cell sorter. Comparison of the lymphocyte subsets in the BALF with those of the peripheral blood revealed much higher values for the ratios of each...

journal_title：Scandinavian journal of immunology

authors： Yamada M,Tamura N,Shirai T,Kira S

更新日期：1986-11-01 00:00:00

abstract：:T cell precursors in the chick embryo have been localized into the intraembryonic mesenchyme (IEM) and into the para-aortic region before the first wave of the thymic colonization on embryonic day (ED) 6,5-8. The cell surface markers of avian prethymic stem cells are not known. It is also not known whether these precu...

journal_title：Scandinavian journal of immunology

authors： Lampisuo M,Karvinen J,Petteri Arstila T,Lassila O

更新日期：1995-01-01 00:00:00

abstract：:With the use of the fluorescent Ca++ indicator Quin-2, we have measured changes in intracellular calcium levels in human B cells in response to anti-Ig antibodies, to Staphylococcus aureus (Staph) or to protein A. Cells of an Epstein-Barr virus-transformed mu lambda-carrying B-cell line, AZU-1, increased free cytosoli...

journal_title：Scandinavian journal of immunology

authors： Clevers HC,Bloem AC,Gmelig-Meyling F,Ballieux RE

更新日期：1985-11-01 00:00:00

abstract：:The thymus is the major primary immune tissue for the production of functional T lymphocytes in vertebrates. However, its evolutionary origin is unknown. It has recently been shown that the generation of local T cells also occurs in gut-associated lymphoid tissues (GALT). This suggests that the thymus and GALT have si...

journal_title：Scandinavian journal of immunology

authors： Matsunaga T,Rahman A

更新日期：2001-01-01 00:00:00

abstract：:CD47 is a versatile cell-surface molecule expressed on nearly all haematopoietic cells. In its capacity as a thrombospondin-1 (TSP-1) receptor, CD47 has recently been shown to mediate cell death in certain cells, for example, activated but not resting T cells. Here, we have investigated the possibility that human mono...

journal_title：Scandinavian journal of immunology

authors： Johansson U,Higginbottom K,Londei M

更新日期：2004-01-01 00:00:00

abstract：:Some data suggest that the interaction between CD28 and CD80 (B7.1) stimulates Th1-responses and that CD28 and CD86 (B7.2) stimulates Th2-responses, however this is controversial. We addressed this issue by using mercuric chloride (HgCl2)-induced autoimmunity in Brown Norway (BN) rats as a highly polarized Th2 model a...

journal_title：Scandinavian journal of immunology

authors： MacPhee IA,Turner DR,Yagita H,Oliveira DB

更新日期：2001-11-01 00:00:00

abstract：:The role of several adhesion molecules for lymphocyte-endothelial interactions in the synovia of rheumatoid arthritis patients was studied using the frozen section assay. Partial inhibition of lymphocyte binding to endothelium of synovial sections could be observed with antibodies against CD44, L-selectin, and beta 1-...

journal_title：Scandinavian journal of immunology

authors： Fischer C,Thiele HG,Hamann A

更新日期：1993-08-01 00:00:00

abstract：:In the sera of patients with acute bacterial infections specific autoantibodies (sIAPa) of the immunoglobulin class G (IgG) were found which bind to intestinal alkaline phosphatase (IAP) through the Fab portion. This was demonstrated using immunoaffinity (IA) isolation of sIAPa from patients' sera (particularly bacter...

journal_title：Scandinavian journal of immunology

authors： Kolbus N,Beuche W,Schlaf G,Nüsslein HG,Felgenhauer K,Mäder M

更新日期：1995-04-01 00:00:00

abstract：:This study (1) analysed the percentage of γδ T cells, γδ T cell subsets, Th17 cells and regulatory T cells (Treg cells) and (2) determined the role of IL-23 in primary nephrotic syndrome (PNS) patients with active disease and in remission. Eighty-four patients with PNS and 51 healthy age-matched controls were included...

journal_title：Scandinavian journal of immunology

authors： Zhang L,Yan J,Yang B,Zhang G,Wang M,Dong S,Liu W,Yang H,Li Q

更新日期：2018-01-01 00:00:00

abstract：:Antibodies forming a complex with antigen in vivo can dramatically change the antibody response to this antigen. In some situations, the response will be a 100-fold stronger than in animals immunized with antigen alone, and in other situations, the response will be completely suppressed. IgG is known to suppress the a...

journal_title：Scandinavian journal of immunology

authors： Xu H,Heyman B

更新日期：2020-10-01 00:00:00

abstract：:Physical association was measured between MLV gp70, the envelope glycoprotein of Rauscher murine leukaemia virus (R-MLV), and serologically defined H-2 antigens on the surface of R-MLV transformed C57BL/6 (H-2DbKb) mouse leukaemia cells (RBL-5A). Capping and patching with antisera against H-2Db caused specific co-capp...

journal_title：Scandinavian journal of immunology

authors： Zarling DA,Keshet I,Watson A,Bach FH

更新日期：1978-01-01 00:00:00

abstract：:A heterologous antiserum (antiserum 7420) against B-lymphocyte antigen(s) was raised in a rabbit by immunization with peripheral blood lymphocytes from a patient with chronic lymphocytic leukaemia (CLL). After absorptions with pooled normal human serum, IgA, IgD, and IgM M-components, the fluorescein isothiocyanate-co...

journal_title：Scandinavian journal of immunology

authors： Berntorp E,Turesson I,Zettervall O

更新日期：1979-01-01 00:00:00

abstract：:The fluid-phase terminal complement complex (TCC), consisting of the components C5b, C6, C7, C8, C9, and the S-protein, has recently been detected in normal human plasma by using antibodies against native terminal complement components. Increased amounts of TCC were then found in several patients with in vivo activati...

journal_title：Scandinavian journal of immunology

authors： Mollnes TE,Lea T,Frøland SS,Harboe M

更新日期：1985-08-01 00:00:00

abstract：:A search for an antigen-driven expansion of T lymphocytes in the inflamed joints in rheumatoid arthritis (RA) patients have been going on for decades. We here analyzed the human germinal centre T-cell receptor (TCR) Vbeta gene usage with polymerase chain reaction (PCR) combined with sequence analysis, to address the q...

journal_title：Scandinavian journal of immunology

authors： Källberg E,Leanderson T,Natvig JB

更新日期：2001-09-01 00:00:00

abstract：:The J-chain content of 3 IgM and 24 IgA preparations was quantitated by an immunochemical technique after reduction with 20mM dithiothreitol. The amounts released ranged from undetectable (less than 0.1 mg) to 7.3 mg per 100 mg of Ig. Most of the J-chain-deficient proteins were monomeric, but four polymeric IgA prepar...

journal_title：Scandinavian journal of immunology

authors： Brandtzaeg P

更新日期：1976-01-01 00:00:00

abstract：:Denaturing high-performance liquid chromatography (DHPLC) was evaluated as a tool for diagnostic screening of polymorphisms in the tumour necrosis factor receptor superfamily member 6 (TNFRSF6) also known as CD95, Apo-1 or Fas gene. Exons 1-9 of the TNFRSF6 gene were amplified from genomic DNA of 38 individuals, of wh...

journal_title：Scandinavian journal of immunology

authors： Etokebe GE,Abrahamsen TG,Bogen B,Spurkland A

更新日期：2004-05-01 00:00:00

abstract：:Beta 2-microglobulin (beta 2m) constitutes the common light chain of both the MHC-encoded HLA-ABC molecules and a group of structurally related glycoproteins recognized by antibodies of the first cluster of differentiation (CD1a, CD1b and CD1c). These CD1 antigens appear similar to murine T1 and Qa molecules in terms ...

journal_title：Scandinavian journal of immunology

authors： Jones RA,Child JA,Master PS,Scott CS

更新日期：1991-07-01 00:00:00

abstract：:IgG1 is cleaved in vitro by granulocyte elastase into Fc and Fab fragments. The elastase-specific Fc fragment has been previously detected in vivo. Biological activity of the fragments has been described in modulating neutrophil oxidative metabolism and enzyme release. To investigate further effects granulocyte chemot...

journal_title：Scandinavian journal of immunology

authors： Eckle I,Kolb G,Havemann K

更新日期：1991-09-01 00:00:00

abstract：:IgE levels in cord blood have been investigated as predictors of atopy, but no definitive findings have been made. Other factors, including cells and/or cytokines may serve as predictors of this disease. Cord blood and peripheral blood was obtained at birth and at 7 months of age, respectively, from children (n = 2) w...

journal_title：Scandinavian journal of immunology

authors： Smith-Norowitz TA,Norowitz KB,Silverberg JI,Chice S,Shah V,Stanek A,Walker D,Brennan JP,Durkin HG,Bluth MH

更新日期：2008-11-01 00:00:00