Intraembryonic haemopoietic cells and early T cell development.

abstract：:The CD4 molecule is an important cell surface molecule expressed on many cell types including T-helper cells. CD4 can be shed from cells, and the truncated soluble form of CD4 (sCD4) has been found elevated in serum in several diseases. In this study the authors show that migration of polymorphonuclear neutrophils (PM...

journal_title：Scandinavian journal of immunology

authors： Goto H,Gidlund M

更新日期：1996-06-01 00:00:00

abstract：:The production of antibody by human colostral cells was assayed by the hemolysis in-gel technique. When sheep erythrocytes coated with O antigens from frequently encountered Escherichia coli bacteria were used as detector cells and anti-IgA serum was added for development, numerous plaque-forming cells (PFC) were demo...

journal_title：Scandinavian journal of immunology

authors： Ahlstedt S,Carlsson B,Hanson LA,Goldblum RM

更新日期：1975-09-01 00:00:00

abstract：:The functional T-cell repertoire in the inflamed joint of a patient with rheumatoid arthritis was analysed at the clonal level. Using limiting dilution techniques and selecting for growth of in vivo activated and/or autoreactive T cells, 149 T-cell lines were established. They were tested in a proliferation assay for ...

journal_title：Scandinavian journal of immunology

authors： Melchers I,Jooss-Rüdiger J,Peter HH

更新日期：1997-08-01 00:00:00

abstract：:Coexistence of amyloid fibril protein AA and homogeneous immunoglobulin light-chain fragments was found in the isolated amyloid fibrils of two patients with amyloidosis secondary to rheumatoid arthritis. The light-chain amyloid fibril protein showed antigenic identity with a light-chain amyloid from a patient with pri...

journal_title：Scandinavian journal of immunology

authors： Westermark P,Natvig JB,Anders RF,Sletten K,Husby G

更新日期：1976-01-01 00:00:00

abstract：:The authors have recently shown that the ability of immune complexes (IC) to trigger Fc gamma R-dependent cell responses can be dramatically enhanced when the isoelectric point (pI) of normal IgG antibodies is increased from 5.8-8.5 to 8.5-9.8 by treatment with 1-ethyl-3-2(3-dimethylaminopropyl) carbodiimide HCl and e...

journal_title：Scandinavian journal of immunology

authors： Trevani AS,Andonegui G,Kempfer C,Malchiodi E,Geffner JR

更新日期：1996-03-01 00:00:00

abstract：:Acanthamoeba polyphaga (AP) is ubiquitous in nature and frequently infects humans. AP has some features, such as persistence, which makes it an attractive candidate in studies of a possible infectious aetiology in rheumatoid arthritis (RA). In this study the occurrence of AP-specific antibodies was compared between RA...

journal_title：Scandinavian journal of immunology

authors： Jeansson S,Kvien TK

更新日期：2001-06-01 00:00:00

abstract：:A method of separating neutrophils from the peripheral blood of rats with 95% purity is described. To determine the role of antigenic stimulation in neutrophil function, neutrophils from germ-free (GF) rats were compared with those of conventional (CV) rats. Neutrophil counts were lower in GF rats but the total number...

journal_title：Scandinavian journal of immunology

authors： Ohkubo T,Tsuda M,Tamura M,Yamamura M

更新日期：1990-12-01 00:00:00

abstract：:In subjects not developing allergy, inhalation of nonpathogenic protein antigens causes no harm and is associated with tolerance induction. Repeated exposure to aerosolized ovalbumin (OVA) likewise does not evoke airway inflammation and induces inhalation tolerance in experimental animals. The present study explored t...

journal_title：Scandinavian journal of immunology

authors： Alenmyr L,Matheu V,Uller L,Greiff L,Malm-Erjefält M,Ljunggren HG,Persson CG,Korsgren M

更新日期：2005-11-01 00:00:00

abstract：:Lymphatic filariasis, a mosquito-borne parasitic disease, affects more than 120 million people worldwide. Vaccination for filariasis by targeting different stages of the parasite will be a boon to the existing MDA efforts of WHO which required repeated administration of the drug to reduce the infection level and susta...

journal_title：Scandinavian journal of immunology

authors： Anugraha G,Madhumathi J,Prince PR,Prita PJ,Khatri VK,Amdare NP,Reddy MV,Kaliraj P

更新日期：2015-10-01 00:00:00

abstract：:With the aim of investigating the distribution of T cells expressing different T-cell receptors (TCR) in the inflamed synovial tissue of rheumatoid arthritis patients, we have used the polymerase chain reaction to amplify TCR V alpha and V beta transcripts from synovial biopsies obtained by arthroscopy from patients w...

journal_title：Scandinavian journal of immunology

authors： Bucht A,Oksenberg JR,Lindblad S,Grönberg A,Steinman L,Klareskog L

更新日期：1992-02-01 00:00:00

abstract：:The thymus is the major primary immune tissue for the production of functional T lymphocytes in vertebrates. However, its evolutionary origin is unknown. It has recently been shown that the generation of local T cells also occurs in gut-associated lymphoid tissues (GALT). This suggests that the thymus and GALT have si...

journal_title：Scandinavian journal of immunology

authors： Matsunaga T,Rahman A

更新日期：2001-01-01 00:00:00

abstract：:(C3H/TifxDBA/2)F1 mice, immunized with viable BALB/c plasmacytoma MOPC315 cells, produce antibodies directed against a cell-surface antigen. The strain and tissue distribution of this antigen was identical to that of the plasma cell differentiation alloantigen PC.1. The antigen is absent in the mouse strain C3H/Tif bu...

journal_title：Scandinavian journal of immunology

authors： Gaudernack G,Hannestad K

更新日期：1979-01-01 00:00:00

abstract：:The immune system produces specific antibodies (Ab) against any antigens (Ag) of exogenous and endogenous origins with a diverse repertoire of V-region specificities. The primary V-region repertoire is created by the rearrangement of immunoglobulin (Ig) V-region, D- and J-segments with the insertion of N- and P-sequen...

journal_title：Scandinavian journal of immunology

authors： Sakaguchi N,Maeda K,Kuwahara K

更新日期：2011-06-01 00:00:00

abstract：:Matrix metalloproteinases are involved in leucocyte invasion into the central nervous system (CNS) during meningitis. The aim of the study was to determine whether there are differences in the expression patterns of matrix metalloproteinase-9 (MMP-9) and the tissue inhibitor of metalloproteinase-1 (TIMP-1) in the cere...

journal_title：Scandinavian journal of immunology

authors： Sulik A,Wojtkowska M,Oldak E

更新日期：2008-09-01 00:00:00

abstract：:Antigen-specific lymphocyte hybridomas have been produced by a simple in vitro immunization procedure. Non-immune spleen cells have been activated in vitro, and the B-cell blasts have subsequently been used for somatic cell hybridization. Hybrids secreting monoclonal antibodies to human myoglobin, pig insulin, and ben...

journal_title：Scandinavian journal of immunology

authors： Borrebaeck CA

更新日期：1983-07-01 00:00:00

abstract：:C-reactive protein (CRP) binds to Fcγ-receptors, FcγRIIa (CD32) with high affinity and to FcγRIa (CD64) with low affinity. The binding to CD32 has been shown to be allele specific, that is, it binds to R/R131 but not to H/H131. Little is known about the cooperation of CRP and neutrophilic granulocytes (PMNs) in inflam...

journal_title：Scandinavian journal of immunology

authors： Aas V,Sand KL,Asheim HC,Benestad HB,Iversen JG

更新日期：2013-06-01 00:00:00

abstract：:Metabolic reprogramming plays a critical role in the important cellular metabolic alterations that occur during the activation of immune cells to enable them to adapt to the extracellular environment. Here, we review recent studies on how substrate availability and metabolites mediate the signalling pathways that regu...

journal_title：Scandinavian journal of immunology

authors： Qian X,Yang Z,Mao E,Chen E

更新日期：2018-11-01 00:00:00

abstract：:Human natural killer (NK) cells are able to adhere to xenogeneic porcine endothelial cells (EC) and evidence from in vitro studies as well as animal models suggests a potential role for NK cells in the cellular recognition and damage of porcine xenogeneic tissues. One possible explanation for the observed NK cell-medi...

journal_title：Scandinavian journal of immunology

authors： Schneider MK,Forte P,Seebach JD

更新日期：2001-07-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) participates in innate immunity by detecting lipopolysaccharides (LPS) of Gram-negative bacterial cell walls. TLR4 macrophage expression in mice is modulated by LPS. This fact constitutes, at least partially, the molecular basis for LPS tolerance. Very recently, the effect of interferon-gam...

journal_title：Scandinavian journal of immunology

authors： Moreno C,Merino J,Vázquez B,Ramírez N,Echeverría A,Pastor F,Sánchez-Ibarrola A

更新日期：2004-06-01 00:00:00

abstract：:Conditions for the cloning of alloactivated human lymphocytes by limiting dilution in the presence of interleukin 2 (IL 2) and filler cells have been investigated. Cloning efficiencies were extremely high (at least 40%) when IL 2 derived from pooled peripheral blood mononuclear cells (PBM), stimulated with phytohaemag...

journal_title：Scandinavian journal of immunology

authors： Kahle P,Wernet P,Rehbein A,Kumbier I,Pawelec G

更新日期：1981-11-01 00:00:00

abstract：:Vitamin A is a potential mediator of T helper cells in atherosclerosis. The purpose of this study was to evaluate the effect of vitamin A supplementation on expression of Th17 cells-related IL-17 and RORc genes in atherosclerotic patients. Thirty one atherosclerotic patients and 15 healthy controls were studied for 4 ...

journal_title：Scandinavian journal of immunology

authors： Mottaghi A,Ebrahimof S,Angoorani P,Saboor-Yaraghi AA

更新日期：2014-08-01 00:00:00

abstract：:Mycobacterium tuberculosis (MTB) secretory proteins are generally considered important antigens for immune protection against tuberculosis (TB). An 8.3-kDa secretory antigen of MTB and Mycobacterium bovis bacillus Calmette-Guérin (BCG), called SA5K, was recently identified and cloned in our laboratory. In this report,...

journal_title：Scandinavian journal of immunology

authors： Batoni G,Bottai D,Esin S,Florio W,Pardini M,Maisetta G,Freer G,Senesi S,Campa M

更新日期：2002-07-01 00:00:00

abstract：:The demonstration in the 1960s that T cells collaborated with B cells in enabling antibody responses to simple protein antigens opened up the challenge of how to investigate the interactions of two rare antigen-specific lymphocytes within a vast population. One idea was that T cells made soluble factors that could act...

journal_title：Scandinavian journal of immunology

authors： Waldmann H

更新日期：2005-07-01 00:00:00

abstract：:Secretory component (SC) acts as a receptor for polymeric IgA (pIgA) and pIgM on the basolateral face of secretory epithelia. This study showed that both the production and surface membrane expression of SC were additively up-regulated by tumour necrosis factor-alpha (TNF) and gamma interferon (IFN-gamma) in a human c...

journal_title：Scandinavian journal of immunology

authors： Kvale D,Brandtzaeg P,Løvhaug D

更新日期：1988-09-01 00:00:00

abstract：:We have previously shown that immunization of outbred rodents with cysteine peptidases-based vaccine elicited type 2-biased immune responses associated with consistent and reproducible protection against challenge Schistosoma mansoni. We herein start to elucidate the molecular basis of C57BL/6 mouse resistance to S. m...

journal_title：Scandinavian journal of immunology

authors： Abdel Aziz N,Tallima H,Hafez EA,El Ridi R

更新日期：2016-02-01 00:00:00

abstract：:Antigen 60 (A60), a member of the thermostable macromolecular antigen family (TMA) and main component of old tuberculin and purified protein derivative (PPD), has been purified from the cytoplasm of Mycobacterium bovis BCG; its structure and metabolism have already been described. In the present paper, the action of A...

journal_title：Scandinavian journal of immunology

authors： Cocito C,Baelden MC,Benoit C

更新日期：1987-06-01 00:00:00

abstract：:Antibodies against IL-1 alpha were detected in sera of apparently healthy individuals. The immunoglobulins belonged to the IgG class, particularly IgG1, IgG2, and IgG4. [125I]rIL-1 alpha bound to Fab fragments of IgG, and IgG immune complexes of molecular weights from 160 to 700 kDa were formed in the sera by [125I]rI...

journal_title：Scandinavian journal of immunology

authors： Svenson M,Bagge Hansen M,Bendtzen K

更新日期：1990-12-01 00:00:00

abstract：:Sixteen plasma proteins were studied in the supernatants from 20 successive washings of human leucocytes by a new sensitive immunoelectrophoretic method. In the first few supernatants a fast and parallel decrease in concentration of all proteins took place, but for 11 proteins this was followed by a phase of slow decr...

journal_title：Scandinavian journal of immunology

authors： Andersen MM

更新日期：1982-04-01 00:00:00

abstract：:Coeliac disease (CD) is a very common food-sensitive enteropathy, which is triggered by gluten ingestion and is mediated by CD4(+) T cells. In addition, alterations in the intestinal microbiota that is normally involved in the homeostasis of GALT (gut-associated lymphoid tissue) seem to play a role in CD. In accordanc...

journal_title：Scandinavian journal of immunology

authors： D'Arienzo R,Stefanile R,Maurano F,Mazzarella G,Ricca E,Troncone R,Auricchio S,Rossi M

更新日期：2011-10-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection is a risk factor for thrombotic microangiopathy (TMA). We sought whether a severe deficiency in ADAMTS13, the enzyme specifically involved in the cleavage of von Willebrand factor, was associated with specific presenting features and outcome in HIV-associated TMA. In this p...

journal_title：Scandinavian journal of immunology

authors： Malak S,Wolf M,Millot GA,Mariotte E,Veyradier A,Meynard JL,Korach JM,Malot S,Bussel A,Azoulay E,Boulanger E,Galicier L,Devaux E,Eschwège V,Gallien S,Adrie C,Schlemmer B,Rondeau E,Coppo P,Réseau d'Etude des Microangi

更新日期：2008-09-01 00:00:00