Human schistosomiasis: deficiency of large granular lymphocytes and indomethacin-sensitive suppression of natural killing.

abstract：:Glomeruli in Cryostat sections of foetal and adult renal tissues adsorbed sheep erythrocytes sensitized with IgM antibody and human or mouse complement (EAC). Activated complement was essential for the reaction to occur. The receptor had specificity for the C3b fragment of C3 and is probably of protein or glycoprotein...

journal_title：Scandinavian journal of immunology

authors： Matre R,Tönder O

更新日期：1976-01-01 00:00:00

abstract：:We have compared antibody-dependent cell-mediated cytotoxicity (ADCMC) of human peripheral blood leukocytes (PBL) in three model systems. target cells were 51Cr-labeled mouse mastocytoma cells, chicken erythrocytes (CRBC), and human erythrocytes (HRBC) coated with appropriate heterologous or isologous antisera. Effect...

journal_title：Scandinavian journal of immunology

authors： MacDonald HR,Bonnard GD,Sordat B,Zawodnik SA

更新日期：1975-09-01 00:00:00

abstract：:Mice homologous for the alymphoplasia mutation (aly) show the systemic absence of secondary lymphoid tissues, with disorganized splenic architecture, including the absence of the germinal centre and follicular dendritic cells. In this study, we examined the influence of defects of gut-associated lymphoid tissue (GALT)...

journal_title：Scandinavian journal of immunology

authors： Morimoto M,Yamauchi Y,Shinkawa S,Ishiwata K,Hayashi T

更新日期：2006-05-01 00:00:00

abstract：:The predominant selection of CRI-A-bearing antibodies during the anti-arsonate (ARS) response of A/J mice has been used as a model to analyse the mechanism involved in the process of clonal selection and establishment of predominance. In order to assess the importance of the affinity and adaptability of CRI-A clones i...

journal_title：Scandinavian journal of immunology

authors： Gaya A,Alsinet E,Freixas M,Vives J

更新日期：1988-09-01 00:00:00

abstract：:Peripheral CD4 T-cell depletion has been observed in human immunodeficiency virus (HIV)-negative patients with pulmonary tuberculosis (TB). To investigate more accurately this alteration, we studied peripheral blood CD45RA(+) and CD29(high) CD4 subsets in 79 TB patients with (HIV(+)TB(+)) or without (HIV(-)TB(+)) HIV ...

journal_title：Scandinavian journal of immunology

authors： Diagbouga S,Chiron JP,Sanou O,Ledru E

更新日期：2001-01-01 00:00:00

abstract：:Midtrimester amniotic fluid cytokines may reflect the function of the maternal immune system in the maternal-fetal interface and thus be predictive of pre-eclampsia. We determined the concentrations of interleukin (IL)-6, IL-8, IL-10, IL-11, IL-12, IL-15, tumour necrosis factor (TNF)-alpha and transforming growth fact...

journal_title：Scandinavian journal of immunology

authors： Heikkinen J,Möttönen M,Pulkki K,Lassila O,Alanen A

更新日期：2001-03-01 00:00:00

abstract：:In subjects not developing allergy, inhalation of nonpathogenic protein antigens causes no harm and is associated with tolerance induction. Repeated exposure to aerosolized ovalbumin (OVA) likewise does not evoke airway inflammation and induces inhalation tolerance in experimental animals. The present study explored t...

journal_title：Scandinavian journal of immunology

authors： Alenmyr L,Matheu V,Uller L,Greiff L,Malm-Erjefält M,Ljunggren HG,Persson CG,Korsgren M

更新日期：2005-11-01 00:00:00

abstract：:CD25 monoclonal antibody binding to the alpha-chain of the Interleukin-2 (IL-2) receptor, blocks high-affinity IL-2 binding, thereby preventing complete T-cell activation and being of ample importance in transplantation medicine and potentially the treatment of autoimmune disease. However, CD25 antibodies do not only ...

journal_title：Scandinavian journal of immunology

authors： Richter GH,Mollweide A,Hanewinkel K,Zobywalski C,Burdach S

更新日期：2009-09-01 00:00:00

abstract：:To determine whether psoriatic keratinocytes differ from normal keratinocytes in their response to gamma interferon, epidermal cell suspensions from normal and from lesional and uninvolved psoriatic skin were cultured in the presence of gamma interferon and the induction of HLA-DR expression and inhibition of cell gro...

journal_title：Scandinavian journal of immunology

authors： Baker BS,Powles AV,Valdimarsson H,Fry L

更新日期：1988-12-01 00:00:00

abstract：:Using cytotoxic effector cells of different anti-H-2 specificities, new cell-mediated lympholysis targets, normally undetected on Meth. A tumour cells, were shown after passage with vaccinia or Moloney virus. The H-2d CML targets on Meth. A cells recognized by B10.BR anti-B10.D2 effector cells were presented only afte...

journal_title：Scandinavian journal of immunology

authors： Matossian-Rogers A,Garrido F,Festenstein H

更新日期：1977-01-01 00:00:00

abstract：:This paper describes a technique utilizing rosette formation with sheep red blood cells as a human T lymphocyte marker, and separation of T cells by rosette sedimentation. ...

journal_title：Scandinavian journal of immunology

authors： Jondal M

更新日期：1976-06-01 00:00:00

abstract：:Interleukin (IL)-12 has dominated the field of cell-mediated immunity since its discovery more than 10 years ago, and clearly plays an essential role in the development of Th1 cells under a variety of conditions. Recent studies now indicate that the importance of IL-12 is not limited to initiating an immune response, ...

journal_title：Scandinavian journal of immunology

authors： Park AY,Scott P

更新日期：2001-06-01 00:00:00

abstract：:Multifactorial involvement in the pathogenesis of autoimmune NZB/W F1 mice has been well documented. To further elucidate the role of cytokines in the disease development of murine lupus, single spleen cells isolated from NZB/W F1 and non-autoimmune C57BL/6 mice were stimulated with T cell mitogens or anti-CD3 antibod...

journal_title：Scandinavian journal of immunology

authors： Lin LC,Chen YC,Chou CC,Hsieh KH,Chiang BL

更新日期：1995-10-01 00:00:00

abstract：:In 10 blood samples from mothers who were studied after the delivery of a male infant and who had Y-body-containing cells in their circulations (mean value, 0.06%) the proportions of surface-Ig- and Y-body-positive lymphocytes were determined after passage through nylon wool. In each case one part of the sample was tr...

journal_title：Scandinavian journal of immunology

authors： Schröder J

更新日期：1975-01-01 00:00:00

abstract：:Native agarose beads (diameter 5-10 micron), activators of the alternative complement pathway, are slowly phagocytosed when incubated with human monocytes cultured under serum-free conditions. Agarose beads preincubated with monocyte cultures and then transferred to new cultures are more easily phagocytosed than nativ...

journal_title：Scandinavian journal of immunology

authors： Hetland G,Eskeland T

更新日期：1986-03-01 00:00:00

abstract：:Modified C-reactive protein (mCRP) has been reported to non-specifically bind to immunoglobulins; notwithstanding, the nature of these interactions is not clear. The aim of this study was to investigate the binding of antibodies directed against HSA and IgG to mCRP, fibrinogen (Fg), IgG, fibronectin (Fn) and C1q and i...

journal_title：Scandinavian journal of immunology

authors： Boncler M,Dudzińska D,Nowak J,Watała C

更新日期：2012-07-01 00:00:00

abstract：:γδ T cells are characterized by recognizing conserved endogenous and stress-induced antigens without antigen presentation. It has been show that γδ T cells play an important role in anti-tumour/microbe responses, but their function in autoimmune diseases is yet not clear. Here, we reported the quantity and phenotype o...

journal_title：Scandinavian journal of immunology

authors： Wang L,Kang N,Zhou J,Guo Y,Zhang X,Cui L,Ba D,He W

更新日期：2012-07-01 00:00:00

abstract：:We have studied the effect of interferon in vivo (induced by polyinosinic-polycytidylic acid (pIC] on the natural killer (NK) cell lytic activity and on the numbers of large granular lymphocytes (LGL) and target-binding cells (TBC) in different lymphoid compartments. One day after the pIC induction the spleen containe...

journal_title：Scandinavian journal of immunology

authors： Hurme M,Silvennoinen O,Renkonen R

更新日期：1984-10-01 00:00:00

abstract：:Cell surface molecules of rat normal lymphoid cells were selectively labelled by lactoperoxidase catalysed iodination or by a galactose oxidase tritiated sodium borohydride technique, subsequently detergent solubilized, isolated by indirect immunoprecipitation and analysed on SDS-polyacrylamide gel electrophoresis. Fo...

journal_title：Scandinavian journal of immunology

authors： Nilsson F,Wigzell H

更新日期：1978-04-01 00:00:00

abstract：:Pretreatment with D-Penicillamine of rat peritoneal macrophages markedly influences their ability to modulate Concanavalin A stimulated [3H]thymidine incorporation in non-adherent rat lymph node cells. Untreated macrophages added in high numbers to the lymphocytes (ratio lymphocytes/macrophage 7.5 : 1) depress their [...

journal_title：Scandinavian journal of immunology

authors： Binderup L,Bramm E,Arrigoni-Martelli E

更新日期：1978-04-01 00:00:00

abstract：:We evaluated the B-cell response in cerebrospinal fluid (CSF) and blood by enumerating cells secreting antibodies to myelin-associated glycoprotein (MAG) and, for reference, to myelin basic protein (MBP), two myelin components which may constitute targets for autoimmune attack in multiple sclerosis (MS). Among 25 untr...

journal_title：Scandinavian journal of immunology

authors： Baig S,Olsson T,Yu-Ping J,Höjeberg B,Cruz M,Link H

更新日期：1991-01-01 00:00:00

abstract：:Histoplasma capsulatum is a fungus found intracellularly in neutrophils and peripheral blood mononuclear cells (PBMCs), suggesting that it is capable of evading damage and survives inside these cells. In this study, we report that neutrophils from H. capsulatum-infected mice, and human neutrophils and mononuclear cell...

journal_title：Scandinavian journal of immunology

authors： Medeiros AI,Bonato VL,Malheiro A,Dias AR,Silva CL,Faccioli LH

更新日期：2002-10-01 00:00:00

abstract：:The natural tolerance to alpha-fetoprotein (AFP) was broken in rabbits by immunizations with purified AFP from different species and homologous AFP chemically modified by haptenation. Some of the rabbits were boostered with rabbit AFP. The highest titers were obtained with human AFP, which shows a strong cross-reactio...

journal_title：Scandinavian journal of immunology

authors： Pihko H

更新日期：1976-01-01 00:00:00

abstract：:Leukoplakias (LPLs) are lesions in the oral mucosa that may develop into oral squamous cell carcinoma (OSCC). The objective of this study was to assess presence and distribution of dendritic Langerhans cells (LCs) and T cells in patients with LPLs with or without cell dysplasia and in oral squamous cell carcinoma (OSC...

journal_title：Scandinavian journal of immunology

authors： Öhman J,Magnusson B,Telemo E,Jontell M,Hasséus B

更新日期：2012-07-01 00:00:00

abstract：:Antigen-specific lymphocyte hybridomas have been produced by a simple in vitro immunization procedure. Non-immune spleen cells have been activated in vitro, and the B-cell blasts have subsequently been used for somatic cell hybridization. Hybrids secreting monoclonal antibodies to human myoglobin, pig insulin, and ben...

journal_title：Scandinavian journal of immunology

authors： Borrebaeck CA

更新日期：1983-07-01 00:00:00

abstract：:Coeliac disease probably results from a T-cell response to wheat gliadin and is associated to HLA-DQ2. No gliadin epitopes recognized by intestinal T cells have yet been identified, limiting our understanding of the pathogenesis. Gut-lesion-derived DQ2-restricted T cells from coeliac disease patients were used to iden...

journal_title：Scandinavian journal of immunology

authors： Sjöström H,Lundin KE,Molberg O,Körner R,McAdam SN,Anthonsen D,Quarsten H,Norén O,Roepstorff P,Thorsby E,Sollid LM

更新日期：1998-08-01 00:00:00

abstract：:RUTI is a vaccine consisting of Mycobacterium tuberculosis bacilli grown in stress conditions that is fragmented, detoxified and liposomed. RUTI was designed to shorten the treatment of latent tuberculosis infection (LTBI) with isoniazid from 9 months to just 1 month, by additional treatment with two inoculations of R...

journal_title：Scandinavian journal of immunology

authors： Vilaplana C,Ruiz-Manzano J,Gil O,Cuchillo F,Montané E,Singh M,Spallek R,Ausina V,Cardona PJ

更新日期：2008-06-01 00:00:00

abstract：:There is strong evidence from animal models that placental and/or breast milk-mediated transfer of maternal allergen-specific IgG prevents allergic immune responses in the progeny. Both human and animal data also point to IgA as having an important regulatory role. In contrast, little is known about maternal transfer ...

journal_title：Scandinavian journal of immunology

authors： Macchiaverni P,Arslanian C,Frazão JB,Palmeira P,Russo M,Verhasselt V,Condino-Neto A

更新日期：2011-12-01 00:00:00

abstract：:An immunization protocol that induces antibodies (Abs) directed to cryptic epitopes of a protein antigen (Ag) reduces the efficacy of vaccines that ideally should induce Abs against native epitopes. We have shown earlier that viral infections concomitant with immunization against a protein tend to shift the Ab specifi...

journal_title：Scandinavian journal of immunology

authors： Gómez KA,Longhi SA,Marino VJ,Mathieu PA,Loureiro ME,Coutelier JP,Roguin LP,Retegui LA

更新日期：2003-02-01 00:00:00

abstract：:To study the role of Natural Killer (NK) cells in Leishmania infection, peritoneal macrophages from BALB/c mice were infected with Leishmania (Leishmania) amazonensis promastigotes and incubated with interleukin-2 (IL-2)-activated NK (A-NK) cells at different ratios of A-NK cells to infected macrophages (5:1, 1:1, 0.2...

journal_title：Scandinavian journal of immunology

authors： Aranha FC,Ribeiro U Jr,Basse P,Corbett CE,Laurenti MD

更新日期：2005-10-01 00:00:00