Atrial fibrillation: inflammation in disguise?

abstract：:Chronic hepatitis B virus (HBV) infection affects millions of people worldwide and about half a million people die every year. India represents the second largest pool of chronic HBV infections with an estimated 40 million chronically infected patients. Persistence or clearance of HBV infection mainly depends upon hos...

journal_title：Scandinavian journal of immunology

authors： Vyas AK,Jindal A,Hissar S,Ramakrishna G,Trehanpati N

更新日期：2017-07-01 00:00:00

abstract：:The production of antibody by human colostral cells was assayed by the hemolysis in-gel technique. When sheep erythrocytes coated with O antigens from frequently encountered Escherichia coli bacteria were used as detector cells and anti-IgA serum was added for development, numerous plaque-forming cells (PFC) were demo...

journal_title：Scandinavian journal of immunology

authors： Ahlstedt S,Carlsson B,Hanson LA,Goldblum RM

更新日期：1975-09-01 00:00:00

abstract：:Natural killer (NK) cells represent the first line of defence against viral infections but, in the case of hepatitis B virus (HBV), may also be involved in liver injury. We here compared NK-cell activity of 11 patients with acute HBV infection, either HIV-positive or HIV-negative, with that of 11 healthy subjects. One...

journal_title：Scandinavian journal of immunology

authors： Morsica G,Tasca S,Biswas P,Galli A,Malnati M,Paties C,Marinelli M,Bagaglio S,Lazzarin A,Fortis C

更新日期：2005-09-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) participates in innate immunity by detecting lipopolysaccharides (LPS) of Gram-negative bacterial cell walls. TLR4 macrophage expression in mice is modulated by LPS. This fact constitutes, at least partially, the molecular basis for LPS tolerance. Very recently, the effect of interferon-gam...

journal_title：Scandinavian journal of immunology

authors： Moreno C,Merino J,Vázquez B,Ramírez N,Echeverría A,Pastor F,Sánchez-Ibarrola A

更新日期：2004-06-01 00:00:00

abstract：:A method of isolation has been developed to purify mast cells from human lung tissue. The purification steps are: (1) dispersion of human lung tissue in single-cell suspensions by enzymatic digestion, (2) partial purification by counterflow centrifugal elutriation, (3) Percoll gradient centrifugation, and (4) enrichme...

journal_title：Scandinavian journal of immunology

authors： van Overveld FJ,Terpstra GK,Bruijnzeel PL,Raaijmakers JA,Kreukniet J

更新日期：1988-01-01 00:00:00

abstract：:In a prospective clinical study in New Halfa Teaching Hospital, the possible association between FcgammaRIIa-R/H131 polymorphism and anti-malarial antibody responses with clinical outcome of Plasmodium falciparum malaria among Sudanese patients was investigated. A total of 256 individuals were consecutively enrolled, ...

journal_title：Scandinavian journal of immunology

authors： Nasr A,Iriemenam NC,Troye-Blomberg M,Giha HA,Balogun HA,Osman OF,Montgomery SM,ElGhazali G,Berzins K

更新日期：2007-07-01 00:00:00

abstract：:Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease, which is characterized with overactive immune response. It is well established that the imbalance between Tregs and Th17 cells plays a pivotal role in pathogenesis of UC. In this study, we investigated the impact of functional changes in Treg subs...

journal_title：Scandinavian journal of immunology

authors： Long Y,Zhao X,Xia C,Li X,Fan C,Liu C,Wang C

更新日期：2020-06-01 00:00:00

abstract：:In a previous report the authors demonstrated that acute graft-versus-host disease (GVHD) was associated with pathologic amounts of tumour necrosis factor alpha (TNF-alpha) and the appearance of lipopolysaccharide (LPS) in the blood of GVH reactive mice just prior to death. In this study the authors have investigated ...

journal_title：Scandinavian journal of immunology

authors： Price KS,Nestel FP,Lapp WS

更新日期：1997-03-01 00:00:00

abstract：:In a well-established murine abortion model, stress is thought to trigger fetal rejection by inducing a proinflammatory immune response via substance P (SP), being tumour necrosis factor (TNF)-alpha-producing CD8+ T cells involved. Interestingly, the SP metabolite SP5-11 also binds to SP receptors and mediates SP-like...

journal_title：Scandinavian journal of immunology

authors： Fest S,Zenclussen AC,Joachim R,Hagen E,Demuth HU,Hoffmann T

更新日期：2006-01-01 00:00:00

abstract：:Congenital heart block (CHB) is a conduction abnormality that affects hearts of foetuses and/or newborn to mothers with autoantibodies reactive with the intracellular soluble ribonucleoproteins 48-kD La, 52-kD Ro and 60-kD Ro. CHB carries substantial mortality and morbidity, with more than 60% of affected children req...

journal_title：Scandinavian journal of immunology

authors： Karnabi E,Boutjdir M

更新日期：2010-09-01 00:00:00

abstract：:Neutrophils are essential for the host defence against infection. However, neutrophils may also mediate damage namely during immune mediated pathologies. We therefore tested whether targeting of different cell adhesion molecules with specific monoclonal antibodies might reduce immune mediated neutrophil recruitment bu...

journal_title：Scandinavian journal of immunology

authors： Gonçalves AS,Appelberg R

更新日期：2000-05-01 00:00:00

abstract：:After intravenous injection of 10(5) purified, lymph node (LN)-derived dm2 (H-2d/Ld-) CD4+ T cells into young C.B-17 scid/scid (severe combined immunodeficiency, SCID) mice (H-2d/Ld+), the transplanted Ld-T cells show a selective pattern of engraftment: they repopulate the spleen, the lamina propria of the small intes...

journal_title：Scandinavian journal of immunology

authors： Rudolphi A,Enssle KH,Claesson MH,Reimann J

更新日期：1993-07-01 00:00:00

abstract：:HLA class II determinants were analysed for their role in monocyte-T-cell interactions in the proliferative response to purified protein derivative (PPD). Allogeneic cell combinations of monocytes and T cells were tested with a range of suboptimal PPD concentrations. For each cell combination tested, a summary measure...

journal_title：Scandinavian journal of immunology

authors： van Eden W,Elferink BG,Hermans J,de Vries RR,van Rood JJ

更新日期：1984-12-01 00:00:00

abstract：:The possible immunological relationship between the pattern of Th1/Th2 cytokine production and tuberculin reactivity was assessed in patients with active Mycobacterium tuberculosis infection. The production of the intracellular cytokines interferon (IFN)-gamma and interleukin-4 (IL-4) was measured in CD4(+) and CD8(+)...

journal_title：Scandinavian journal of immunology

authors： Boras Z,Juretić A,Gagro A,Pavelić Lj

更新日期：2007-03-01 00:00:00

abstract：:Inflammatory cytokines appear to be involved in damage to Schwann cells, myelin and axons, although the exact role of the different cytokines is uncertain. The direct injection model offers a new and simplified way of examining the mechanisms of early inflammation in the peripheral nervous system. The present study wa...

journal_title：Scandinavian journal of immunology

authors： Pelidou SH,Deretzi G,Zou LP,Quiding C,Zhu J

更新日期：1999-07-01 00:00:00

abstract：:Exogenously added beta 2-microglobulin (beta 2m) binds to a variety of murine cell types. The 'receptor' for beta 2m has been isolated. The purified 'receptor' comprised a 48,000-dalton chain and occasionally a 25,000-dalton component. Direct crosslinking of beta 2m to the receptor on intact cells gave rise to a singl...

journal_title：Scandinavian journal of immunology

authors： Sege K,Peterson PA

更新日期：1980-01-01 00:00:00

abstract：:Inflammatory infiltrates in sciatic nerves during the acute phase of experimental allergic neuritis in the Lewis rat have been characterized with regard to occurrence and distribution of Ia-expressing cells and T-lymphocyte subsets by the help of an immunohistochemical double-staining technique, enabling the simultane...

journal_title：Scandinavian journal of immunology

authors： Olsson T,Holmdahl R,Klareskog L,Forsum U

更新日期：1983-10-01 00:00:00

abstract：:B-cell-dependent autoantibody production is a hallmark of systemic lupus erythematosus (SLE) which requires costimulatory molecules. The aim of the study was to analyse the expression of costimulatory molecules on B cells in patients with SLE. Twenty-six patients with SLE (four male, 22 female, mean age 46 +/- 15 year...

journal_title：Scandinavian journal of immunology

authors： Dolff S,Wilde B,Patschan S,Dürig J,Specker C,Philipp T,Kribben A,Witzke O

更新日期：2007-11-01 00:00:00

abstract：:Human leucocyte antigen (HLA)-G is an important molecule for maintaining an immunotolerant foetal-maternal relationship. A 14-bp insertion (+14-bp)/deletion (-14-bp) polymorphism in exon 8 of the 3' untranslated region of the HLA-G gene has been proposed to be associated with HLA-G mRNA stability and the expression of...

journal_title：Scandinavian journal of immunology

authors： Zhu Y,Huo Z,Lai J,Li S,Jiao H,Dang J,Jin C

更新日期：2010-01-01 00:00:00

abstract：:Recently, associations were found between several autoimmune diseases and functional variants of interleukin-23 receptor (IL23R) gene; here, we studied the possible association of nine polymorphisms of IL23R with ankylosing spondylitis (AS) and with Sjögren syndrome (SS). In our study, we genotyped groups of patients ...

journal_title：Scandinavian journal of immunology

authors： Sáfrány E,Pazár B,Csöngei V,Járomi L,Polgár N,Sipeky C,Horváth IF,Zeher M,Poór G,Melegh B

更新日期：2009-07-01 00:00:00

abstract：:Human peripheral lymphocytes were cultivated in soft agar or agarose, containing 3H-thymidine or bromodeoxyuridine (BrdU), which is an analogue of thymidine readily incorporated into deoxyribonucleic acid by lymphocytes. Colonies were isolated and analysed by autoradiography or stained with the fluorescence-plus-Giems...

journal_title：Scandinavian journal of immunology

authors： Lindahl-Kiessling K,Karlberg I

更新日期：1981-05-01 00:00:00

abstract：:Mice homologous for the alymphoplasia mutation (aly) show the systemic absence of secondary lymphoid tissues, with disorganized splenic architecture, including the absence of the germinal centre and follicular dendritic cells. In this study, we examined the influence of defects of gut-associated lymphoid tissue (GALT)...

journal_title：Scandinavian journal of immunology

authors： Morimoto M,Yamauchi Y,Shinkawa S,Ishiwata K,Hayashi T

更新日期：2006-05-01 00:00:00

abstract：:Rabbit Ig against human beta2-microglobulin was found to be mitogenic for human peripheral lymphocytes, tonsil lymphocytes, and appendix and spleen cells. Anti-beta2-m gave increased DNA synthesis, with peak responses on day 3 or 4 and showed a dose-response effect when diluted. The effect was seen in both serum-free ...

journal_title：Scandinavian journal of immunology

authors： Ringeén O,Möller E

更新日期：1975-01-01 00:00:00

abstract：:As part of an ongoing project aimed at the characterization of the MHC system in bony fishes, we have attempted to identify the class III region in the zebrafish (a teleost), a region that in higher vertebrates contains genes coding for complement proteins C2, Bf and C4. We obtained several genomic PAC clones by hybri...

journal_title：Scandinavian journal of immunology

authors： Gongora R,Figueroa F,Klein J

更新日期：1998-12-01 00:00:00

abstract：:Coeliac disease probably results from a T-cell response to wheat gliadin and is associated to HLA-DQ2. No gliadin epitopes recognized by intestinal T cells have yet been identified, limiting our understanding of the pathogenesis. Gut-lesion-derived DQ2-restricted T cells from coeliac disease patients were used to iden...

journal_title：Scandinavian journal of immunology

authors： Sjöström H,Lundin KE,Molberg O,Körner R,McAdam SN,Anthonsen D,Quarsten H,Norén O,Roepstorff P,Thorsby E,Sollid LM

更新日期：1998-08-01 00:00:00

abstract：:We evaluated the B-cell response in cerebrospinal fluid (CSF) and blood by enumerating cells secreting antibodies to myelin-associated glycoprotein (MAG) and, for reference, to myelin basic protein (MBP), two myelin components which may constitute targets for autoimmune attack in multiple sclerosis (MS). Among 25 untr...

journal_title：Scandinavian journal of immunology

authors： Baig S,Olsson T,Yu-Ping J,Höjeberg B,Cruz M,Link H

更新日期：1991-01-01 00:00:00

abstract：:Mycobacterium tuberculosis (MTB) secretory proteins are generally considered important antigens for immune protection against tuberculosis (TB). An 8.3-kDa secretory antigen of MTB and Mycobacterium bovis bacillus Calmette-Guérin (BCG), called SA5K, was recently identified and cloned in our laboratory. In this report,...

journal_title：Scandinavian journal of immunology

authors： Batoni G,Bottai D,Esin S,Florio W,Pardini M,Maisetta G,Freer G,Senesi S,Campa M

更新日期：2002-07-01 00:00:00

abstract：:Development of type-II collagen (CII)-induced arthritis (CIA) is dependent on a T-cell mediated activation of autoreactive B cells. However, it is still unclear if B cells can present CII to T cells. To investigate the role of B cells as antigen-presenting cells (APCs) for CII, we purified B cells from lymph nodes of ...

journal_title：Scandinavian journal of immunology

authors： Holmdahl M,Vestberg M,Holmdahl R

更新日期：2002-04-01 00:00:00

abstract：:This study describes Leishmania antigen-induced activation of lymphocytes isolated from Kenyan donors, previously treated for visceral leishmaniasis, and from Danish and Kenyan controls. Peripheral blood mononuclear cells (PBMC) from cured Kala-Azar patients proliferated and produced Interferon-gamma in vitro in respo...

journal_title：Scandinavian journal of immunology

authors： Kemp M,Theander TG,Handman E,Hey AS,Kurtzhals JA,Hviid L,Sørensen AL,Were JO,Koech DK,Kharazmi A

更新日期：1991-02-01 00:00:00

abstract：:Antibody formation in rabbits against sheep erythrocytes (SRBC) was suppressed after injection of anti-SRBC IgG. Suppression did not occur, however, if the injected IgG had an allotypic marker to which the rabbits possessed circulating antibody. ...

journal_title：Scandinavian journal of immunology

authors： Jerne D,Aasted B

更新日期：1976-01-01 00:00:00