Monocyte-T-cell interactions in the regulation of polyclonal B-cell response.

abstract：:The objective of this study was to evaluate whether major abdominal surgery leads to complement activation and interleukin response and whether the kind of anaesthesia influence complement activation and the release of inflammatory interleukins. The study design was prospective and randomised. Fifty patients undergoin...

journal_title：Scandinavian journal of immunology

authors： Kvarnström AL,Sarbinowski RT,Bengtson JP,Jacobsson LM,Bengtsson AL

更新日期：2012-05-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), F10.2 and F10.3, were selected for their ability to interfere in homotypic adhesion of human B cells. Precipitation studies and binding to intercellular adhesion molecule 1 (ICAM-1, CD54) cDNA transfected COS cells revealed that both MoAbs are directed against ICAM-1. The binding of ...

journal_title：Scandinavian journal of immunology

authors： Bloemen P,Moldenhauer G,van Dijk M,Schuurman HJ,Bloem AC

更新日期：1992-05-01 00:00:00

abstract：:We have analysed separately the role of B-cell receptor (BCR) stimulation and the soluble second signal in the T-cell-independent type 2 (TI-2) B-cell response. We were able to show that human B cells and macrophages (Mphi) could function together in TI-type microbial response. Interestingly, BCR cross-linking of peri...

journal_title：Scandinavian journal of immunology

authors： Mättö M,Raunio AR,Postila V,Huttunen K,Hirvonen MR,Pelkonen J

更新日期：2008-03-01 00:00:00

abstract：:During the germinal centre reaction (GC), B cells with non-functional or self-reactive antigen receptors are negatively selected by apoptosis to generate B cell repertoire with appropriate antigen specificities. We studied the molecular mechanism of Fas/CD95- and B cell receptor (BCR)-induced apoptosis to shed light o...

journal_title：Scandinavian journal of immunology

authors： Eeva J,Nuutinen U,Ropponen A,Mättö M,Eray M,Pellinen R,Wahlfors J,Pelkonen J

更新日期：2009-12-01 00:00:00

abstract：:With the aim of producing large quantities of mRNA-transfected monocyte-derived dendritic cells (DCs) to be used as cancer vaccines, a new clinical grade procedure has been developed. Peripheral blood mononuclear cells (PBMCs) obtained by leukapheresis were enriched for monocytes by immunomagnetic depletion of CD19+ B...

journal_title：Scandinavian journal of immunology

authors： Mu LJ,Gaudernack G,Saebøe-Larssen S,Hammerstad H,Tierens A,Kvalheim G

更新日期：2003-11-01 00:00:00

abstract：:The c-Met oncoprotein is a cell-surface receptor for hepatocyte growth factor (HGF). Signals through HGF and c-Met have been appreciated for their crucial roles in the development of many cell types, including liver cells. The present study examined whether c-Met is expressed in the thymus and whether c-Met/HGF signal...

journal_title：Scandinavian journal of immunology

authors： Tamura S,Sugawara T,Tokoro Y,Taniguchi H,Fukao K,Nakauchi H,Takahama Y

更新日期：1998-04-01 00:00:00

abstract：:The study shows that serum from pneumococcal polysaccharide type III (SSSIII)-immunized and nonimmunized mice that has been absorbed until devoid of anti-SSSIII antibodies inhibits anti-SSSIII plaque-forming cells (PFC) but not antisheep red blood PFC in antibody plaque assay. A large fraction of the inhibitions activ...

journal_title：Scandinavian journal of immunology

authors： Pasanen VJ

更新日期：1986-03-01 00:00:00

abstract：:This study investigates local alterations in T-cell and macrophage subsets that occur in cervical epithelial neoplasia (CIN), in the presence and absence of human immunodeficiency virus (HIV) infection. Ectocervical biopsies from 10 women with CIN who were infected with HIV, and 10 women with CIN but no HIV infection ...

journal_title：Scandinavian journal of immunology

authors： Ahmed SM,Al H,Reid WM,Johnson MA,Poulter LW

更新日期：2002-08-01 00:00:00

abstract：:We have previously reported that a cytosolic alkaline fraction (FI) obtained from epimastigotes of Trypanosoma cruzi promotes the activation, proliferation and differentiation of normal murine B cells into antibody-secreting plasmocytes. Neither the mechanism nor the cells involved in the FI-induced polyclonal B-cell ...

journal_title：Scandinavian journal of immunology

authors： Montes CL,Zuñiga E,Minoprio P,Vottero-Cima E,Gruppi A

更新日期：1999-08-01 00:00:00

abstract：:Forty lymphoblast cell lines derived from normal subjects, patients with infectious mononucleosis, leukemia, and Burkitt's lymphoma have been studied for surface receptors including surface Ig, complement receptors by the EAC rosette and fluorescent (Raji cell) techniques, and Fc (aggregate) receptor by direct and ind...

journal_title：Scandinavian journal of immunology

authors： Yount WJ,Utsinger PD,Hutt LM,Buchanan PD,Korn JH,Fuller CR,Logue M,Pagano JS

更新日期：1976-01-01 00:00:00

abstract：:Two cytokines, interferon (IFN) and interleukin 2 (IL-2), activate murine natural killer (NK) cells in vitro. Together both factors synergize considerably. Antibody against IFN eliminates the response of NK cells to IFN as well as to IL-2, whereas antibody against IL-2 blocks the effect of IL-2 but not of IFN. These f...

journal_title：Scandinavian journal of immunology

authors： Chun M,Krim M,Granelli-Piperno A,Hirst JA,Hoffmann MK

更新日期：1985-10-01 00:00:00

abstract：:The expression of chemokines and chemokine receptors was studied in Leishmania donovani (LD)-infected human mononuclear phagocytes and the human monocytic cell line THP1. Our studies showed that LD infection caused the upregulation of three beta chemokines (macrophage inflammatory protein-1 alpha (MIP-1alpha), MIP-1be...

journal_title：Scandinavian journal of immunology

authors： Dasgupta B,Roychoudhury K,Ganguly S,Akbar MA,Das P,Roy S

更新日期：2003-04-01 00:00:00

abstract：:Coeliac disease probably results from a T-cell response to wheat gliadin and is associated to HLA-DQ2. No gliadin epitopes recognized by intestinal T cells have yet been identified, limiting our understanding of the pathogenesis. Gut-lesion-derived DQ2-restricted T cells from coeliac disease patients were used to iden...

journal_title：Scandinavian journal of immunology

authors： Sjöström H,Lundin KE,Molberg O,Körner R,McAdam SN,Anthonsen D,Quarsten H,Norén O,Roepstorff P,Thorsby E,Sollid LM

更新日期：1998-08-01 00:00:00

abstract：:Changes in the concentration and composition of serum immunoglobulin A (IgA) and deposits of IgA in tissues are well-known characteristics of alcoholic liver disease. We investigated whether these changes also accompany IgA synthesis by peripheral blood mononuclear cells (MNC), by counting immunoglobulin-producing cel...

journal_title：Scandinavian journal of immunology

authors： Van de Wiel A,Seifert WF,Van der Linden JA,Gmelig-Meyling FH,Kater L,Schuurman HJ

更新日期：1987-02-01 00:00:00

abstract：:Human endothelial cells (EC), cultured serum-free, synthesize de novo protein which increasingly bind to agarose beads (an alternative pathway activator), until a plateau phase is reached after 24-48 h. EC synthesize functional C3, C5, C6, C8 and C9, which were detected on co-cultured agarose beads, using relevant pol...

journal_title：Scandinavian journal of immunology

authors： Johnson E,Hetland G

更新日期：1991-06-01 00:00:00

abstract：:The role of Lyt 1+ T-cell-derived secondard CTL inducing factor allowed the cloning of alloreactive cytotoxic T lymphocytes (CTL) by the limiting dilution approach. Several monoclonal cell lines were established in vitro. The lytic activity of some of the cell lines exceeded that of CTL from bulk cultures; that is, 50...

journal_title：Scandinavian journal of immunology

authors： Schawaller R,Röllinghoff M,Wagner H

更新日期：1980-01-01 00:00:00

abstract：:Immunisation of female mice with the allergen ovalbumin (OVA) during pregnancy reduces the OVA-specific IgE response in adult offspring. To approach primary prevention strategies for allergy, we investigated to what extent genetic, paternal and maternal factors influence this suppressive effect on allergic sensitisati...

journal_title：Scandinavian journal of immunology

authors： Nygaard UC,Hansen JS,Groeng EC,Melkild I,Løvik M

更新日期：2013-02-01 00:00:00

abstract：:The procoagulant activities of non-elicited mouse monocytes/macrophages from four anatomical localizations were compared. These cell populations were further examined for their ability to increase their procoagulant activity on exposure to endotoxin or phytohaemagglutinin (PHA). Peritoneal macrophages exhibited the hi...

journal_title：Scandinavian journal of immunology

authors： Lyberg T,Amlie E,Kaplun A,Prydz H

更新日期：1983-09-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by susceptibility to bacterial and fungal infections resulting from the inadequacy of phagocytic leucocytes to produce reactive oxygen radicals. CGD is a genetically heterogeneous disease with an X-linked recessive (XR-CGD) form caused by ...

journal_title：Scandinavian journal of immunology

authors： Kutukculer N,Aykut A,Karaca NE,Durmaz A,Aksu G,Genel F,Pariltay E,Cogulu Ö,Azarsız E

更新日期：2019-02-01 00:00:00

abstract：:Cockroaches have been identified as one of the major indoor allergens inducing perennial rhinitis and asthma. Per a 1s are a group of the major allergens from American cockroach. Although Per a 1s are major allergens from American cockroach, factors contributing to the allergenicity of Per a 1s are still poorly define...

journal_title：Scandinavian journal of immunology

authors： He S,Zhang Z,Zhang H,Wei J,Yang L,Yang H,Sun W,Zeng X,Yang P

更新日期：2011-09-01 00:00:00

abstract：:The routine availability of nucleated human cells for experimental use in limited in the absence of venipuncture. In this paper we have demonstrated that macrophages may be harvested routinely from the waste dialysis bags of patients undergoing continuous ambulatory peritoneal dialysis. These cells were identified as ...

journal_title：Scandinavian journal of immunology

authors： Maddox Y,Foegh M,Zeligs B,Zmudka M,Bellanti J,Ramwell P

更新日期：1984-01-01 00:00:00

abstract：:Normal mouse spleen cells were cultured in different conditioned media (CM). Mixed lymphocyte culture supernatant (MLC SN) was shown to promote the proliferation of cytotoxic, Thy-1+, Lyt-1+, Lyt-2+, asialo-GM-1+, weakly adherent cells with numerous vacuoles and lysosome-like cytoplasmic granules. In contrast, the Con...

journal_title：Scandinavian journal of immunology

authors： Courtoy R,Schaaf-Lafontaine N,Degiovanni G,Boniver J

更新日期：1983-08-01 00:00:00

abstract：:The pair of microH-chain and kappa L-chain transgenes encoding the Sp6 TNP/DNA-specific IgM was bred onto the rearrangement-deficient genetic background of RAG-2T mice, and onto the kappa L-chain expression-deficient background of iE kappa T mice. Bone marrow of Sp6 transgenic RAG-2T mice contained normal numbers of B...

journal_title：Scandinavian journal of immunology

authors： Andersson J,Melchers F,Rolink A

更新日期：1995-07-01 00:00:00

abstract：:Bone marrow cells from two patients without detectable monoclonal immunoglobulin (Ig) in serum and urine but with the clinical picture of plasma cell myeloma were cultivated in vitro. Immunofluorescence studies of cultured living and fixed bone marrow cells showed no signs of Ig production in one of the cases, whereas...

journal_title：Scandinavian journal of immunology

authors： Nilsson K,Killander D,Killander J,Mellstedt H

更新日期：1976-01-01 00:00:00

abstract：:To examine the possible relationship between the cells mediating resistance to tumour cells and those mediating rejection of foreign bone marrow transplants (BMT), the effect of tumour-bearing on BMT rejection has been measured by means of the spleen colony assay. Moderate doses (less than 5.0 X 10(6] of bone marrow c...

journal_title：Scandinavian journal of immunology

authors： Miller SC,Nguyen D,Bird IA

更新日期：1988-04-01 00:00:00

abstract：:A clear correlation was observed between the presence of an Ia-like antigenic B-cell system Ly-Li, detected serologically, and three cellular immunological techniques: [1] mixed lymphocyte reaction (MLR) inhibition by an anti-Li antiserum; [2] level of restimulation of anti-Ly-Li in-vitro-primed lymphocytes; and [3] d...

journal_title：Scandinavian journal of immunology

authors： Sasportes M,Mawas C,Crosier P,Charmot D,Legrand L,Dausset J

更新日期：1977-01-01 00:00:00

abstract：:Pemphigus vulgaris is a cutaneous autoimmune disease in which the occurrence of autoantibodies directed against desmoglein-3 and other self-antigens has been well established in patient sera. However, V-region interactions (connectivity) of serum IgG and IgM have not been analysed to date. In this report, it has been ...

journal_title：Scandinavian journal of immunology

authors： Pacheco-García U,Tovar-Rivera T,Padierna-Olivos L,Rojas-Espinosa O,Sánchez-Colón S,Gutiérrez-Armenta M,Rivera-Benítez C,Masso-Rojas F,Sánchez-García FJ

更新日期：1999-04-01 00:00:00

abstract：:Normal human B lymphocytes and Epstein-Barr virus-transformed B-cell lines can produce reactive oxygen species such as superoxide if treated with phorbol myristate acetate (PMA) or with the surface immunoglobulin cross-linking agents protein A and anti-immunoglobulin. Here, we investigated under which conditions speci...

journal_title：Scandinavian journal of immunology

authors： Maly FE,Urwyler A,Tengler R,Steinitz M,Golding B,de Weck AL

更新日期：1990-12-01 00:00:00

abstract：:We have depleted lymphocyte subsets in PVG and AO rats with MoAbs 3.2.3 (against NKR-P1 on NK and NK/T cells) and OX-8 (against CD8 on CTL and NK cells), and examined the effect on the killing of YAC-1 target cells in vitro and the effect on the acute rejection of small allogeneic lymphocytes in vivo (allogeneic lymph...

journal_title：Scandinavian journal of immunology

authors： Løvik G,Vaage JT,Rolstad B,Naper C

更新日期：2001-10-01 00:00:00

abstract：:The authors have recently shown that the ability of immune complexes (IC) to trigger Fc gamma R-dependent cell responses can be dramatically enhanced when the isoelectric point (pI) of normal IgG antibodies is increased from 5.8-8.5 to 8.5-9.8 by treatment with 1-ethyl-3-2(3-dimethylaminopropyl) carbodiimide HCl and e...

journal_title：Scandinavian journal of immunology

authors： Trevani AS,Andonegui G,Kempfer C,Malchiodi E,Geffner JR

更新日期：1996-03-01 00:00:00