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Detection by three cellular immunological techniques of the antigenic determinants of the Ly-Li system, expressed on human B lymphocytes.

Abstract：

:A clear correlation was observed between the presence of an Ia-like antigenic B-cell system Ly-Li, detected serologically, and three cellular immunological techniques: [1] mixed lymphocyte reaction (MLR) inhibition by an anti-Li antiserum; [2] level of restimulation of anti-Ly-Li in-vitro-primed lymphocytes; and [3] detection of HLA-D alleles by homozygous typing cells. These results suggested that the allelic products detected serologically may be identical to those detected by the first two techniques, namely MLR inhibition and in-vitro-primed lymphocyte typing, and, possibly, HLA-D typing using homozygous typing cells, although the correlation was repeatedly found to be less clear for the last technique.

journal_name

Scand J Immunol

journal_title

Scandinavian journal of immunology

authors

Sasportes M,Mawas C,Crosier P,Charmot D,Legrand L,Dausset J

doi

10.1111/j.1365-3083.1977.tb02112.x

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

507-10

issue

5

eissn

0300-9475

issn

1365-3083

journal_volume

6

pub_type

杂志文章

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